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The map label for this gene is clpB [H]

Identifier: 146300338

GI number: 146300338

Start: 3072873

End: 3075419

Strand: Reverse

Name: clpB [H]

Synonym: Fjoh_2583

Alternate gene names: 146300338

Gene position: 3075419-3072873 (Counterclockwise)

Preceding gene: 146300341

Following gene: 146300337

Centisome position: 50.44

GC content: 36.4

Gene sequence:

>2547_bases
ATGGATGATAATTTTTCACCAAGAGTAAAAGATGTTATTACGTACAGTAAGGAAGAAGCCCTTCGTTTAGGACACGACTT
TATTGGTACAGAACATCTTATGCTAGGCATTTTAAGAGATGGTAACGGAAAAGCTATTCATATACTTAATAACCTAGCAG
TTGATTTAGATCATTTACGCAGGAAAGTAGAAATACTGAGCCCGGCAAATCACAGCGTTGAGGTAAATACAGAAAAGAAA
AACCTTCATCTTACCCGACAGGCCGAAAGAGCCCTGAAGACCACTTTTCTTGAAGCTAAAGTATTTCAAAGCTCGTCGAT
AAGCACTGCTCACCTGCTTCTGTGTATCTTACGAAACGAAAACGATCCAACAACCAAGCTGCTGAATAAACTTAAAATAG
ATTATGACGTGGCTAAAGAACAATATTTAAATATGACGCCAAACGAAGAAGAATTCTTAGAAAACTTGCCAAGAAACGAA
TCGTATAATGACGATTCAGGACAAGATGACAGTTTAAAGGAAAGTAGTTTTAATAATCCCGCCAATAAGTCAAACAAAAA
ATCTAAGACTCCGGTTTTAGATAATTTTGGGAGAGATTTAACAGAAATGGCTGAGGAAGGAAAACTAGATCCTGTTGTGG
GACGCGAAAAAGAAATTGAACGTGTTTCGCAGATTTTAAGCCGAAGAAAAAAGAACAACCCGCTTCTTATTGGAGAACCC
GGGGTTGGTAAATCTGCAATTACAGAAGGACTTGCATTACGTATTATTCAAAAGAAAGTATCACGTATTCTTTTCCACAA
ACGTGTTGTTACTCTGGATCTGGCTAGTTTAGTTGCCGGAACAAAATACAGAGGACAATTTGAGGAAAGAATGAAAGCCG
TTATGAACGAGCTTGAGAAAAACGACGATATCATTCTTTTTATTGATGAAATCCATACTATTGTAGGAGCTGGAGGAGCA
ACAGGTTCACTTGATGCGTCTAACATGTTCAAACCTGCTTTAGCAAGAGGTGAAATCCAATGTATTGGTGCTACTACTCT
TGATGAGTACAGACAATATATTGAAAAAGACGGTGCATTAGAAAGACGTTTCCAAAAAGTTATTGTAGAACCAACTTCTG
TTGAAGAAACAATCGCTATTTTAAATAACGTAAAAGACAAATACGAAGATCACCACAATGTAACTTATACACAAGAAGCT
ATTGAAGCCTGTGTTAAACTTACAGATCGTTATATGTCTGAGCGTTTCTTACCAGACAAAGCGATTGATGCTCTTGACGA
AGCCGGATCTCGTGTTCACATTACCAATATTGATGTTCCTAAACAAATTTTAGATTTAGAGCGTCAGTTAGAAGAAGTTC
GCGAAATGAAGAATATGGTAGTTAAAAAACAAAAATATGAAGAAGCTGCCAAACTTCGCGATGACGAAAAACGCATAGAA
AAAGATCTTGCTGCTGCACAAGAACAATGGGAAGAAGATTCTAAAAACAACAGAATTGAAGTTACAGAAGATAATGTAGC
CGATGTTGTTTCAATGATGACCGGAATTCCTGTAAACAGAATTGCACAGACAGAAAGCAATAAATTAGCCAAATTACCTG
AATTAATTCAGAACAAAGTAATTGGTCAAAATGATGCCGTTCTTAAAATTGCACGTTCTATTCAGCGTAACAGAGCCGGA
CTTAAAGATCCAAACAAACCAATTGGTTCGTTTATTTTCTTAGGTCAGACTGGTGTTGGTAAAACACAGCTGGCAAAAGT
ATTAGCAAAAGAATTATTCGATTCTGAAGATGCATTGGTTCGTATCGACATGAGTGAATACATGGAAAAATTTGCTATCT
CTCGTTTAGTTGGAGCGCCTCCGGGATATGTTGGGTACGAAGAAGGCGGACAATTGACTGAGAAAGTTCGTAGAAAACCA
TATTGTGTAGTTCTTTTAGATGAGATCGAAAAAGCACACCCAGATGTATTCAATATGATGCTTCAGGTTTTAGATGACGG
ATATTTAACGGATAGTTTAGGTCGTAAAATTGACTTTAAAAACACTATCATTATCATGACTTCTAACGTTGGTGCACGTC
AGTTAAAAGATTTTGGACAAGGTGTTGGATTTGGTACTGCTGCAAGAACAGCTCAGGCTGATGAAAACTCAAAAAGCATT
ATCGAAAATGCATTAAAGAAAACTTTTGCTCCTGAATTCTTAAACAGAATTGATGACGTAATTGTATTTAATGCACTAGA
AAAAGCTGATATCGATTTGATTATCGAAATCGAATTGAAAAAACTATATTCTCGTATTGCAGAGTTAGGCTACAAGTTAA
GCTTAACTGACAAAGCAAAAGCTTTTATTGCTGAAAAAGGTTTCGATAAACAGTTTGGAGCAAGACCGCTTAAAAGAGCA
ATTCAGAAATATGTTGAAGATTTGCTGGCTGAAGAAATCATCACTTCAAAAATACATTCAGGTGATGAAATTATGATGGA
TCTAAAAGATGATTCGCAAGAACTATCAGTAGAAATTCATAAAGCCGAAGAGCCGACTAATCAATAA

Upstream 100 bases:

>100_bases
TGTTATTTTTTTTGTCAATTAGCTGACAGCAGATCTCGATAGGTATGATTTTTGTTTTTCAACCAGTAAATAATTAAATT
TACACTACCAATTATATATT

Downstream 100 bases:

>100_bases
ATTAGTTAAAATTTATAACAAAAATAATTTACCCGTTACGTTTTCATAACATAACGGGTATTTTTTTTGCAAAAATCACT
ATCTTTAGTAAAAGCAAATA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MDDNFSPRVKDVITYSKEEALRLGHDFIGTEHLMLGILRDGNGKAIHILNNLAVDLDHLRRKVEILSPANHSVEVNTEKK
NLHLTRQAERALKTTFLEAKVFQSSSISTAHLLLCILRNENDPTTKLLNKLKIDYDVAKEQYLNMTPNEEEFLENLPRNE
SYNDDSGQDDSLKESSFNNPANKSNKKSKTPVLDNFGRDLTEMAEEGKLDPVVGREKEIERVSQILSRRKKNNPLLIGEP
GVGKSAITEGLALRIIQKKVSRILFHKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEKNDDIILFIDEIHTIVGAGGA
TGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALERRFQKVIVEPTSVEETIAILNNVKDKYEDHHNVTYTQEA
IEACVKLTDRYMSERFLPDKAIDALDEAGSRVHITNIDVPKQILDLERQLEEVREMKNMVVKKQKYEEAAKLRDDEKRIE
KDLAAAQEQWEEDSKNNRIEVTEDNVADVVSMMTGIPVNRIAQTESNKLAKLPELIQNKVIGQNDAVLKIARSIQRNRAG
LKDPNKPIGSFIFLGQTGVGKTQLAKVLAKELFDSEDALVRIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRKP
YCVVLLDEIEKAHPDVFNMMLQVLDDGYLTDSLGRKIDFKNTIIIMTSNVGARQLKDFGQGVGFGTAARTAQADENSKSI
IENALKKTFAPEFLNRIDDVIVFNALEKADIDLIIEIELKKLYSRIAELGYKLSLTDKAKAFIAEKGFDKQFGARPLKRA
IQKYVEDLLAEEIITSKIHSGDEIMMDLKDDSQELSVEIHKAEEPTNQ

Sequences:

>Translated_848_residues
MDDNFSPRVKDVITYSKEEALRLGHDFIGTEHLMLGILRDGNGKAIHILNNLAVDLDHLRRKVEILSPANHSVEVNTEKK
NLHLTRQAERALKTTFLEAKVFQSSSISTAHLLLCILRNENDPTTKLLNKLKIDYDVAKEQYLNMTPNEEEFLENLPRNE
SYNDDSGQDDSLKESSFNNPANKSNKKSKTPVLDNFGRDLTEMAEEGKLDPVVGREKEIERVSQILSRRKKNNPLLIGEP
GVGKSAITEGLALRIIQKKVSRILFHKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEKNDDIILFIDEIHTIVGAGGA
TGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALERRFQKVIVEPTSVEETIAILNNVKDKYEDHHNVTYTQEA
IEACVKLTDRYMSERFLPDKAIDALDEAGSRVHITNIDVPKQILDLERQLEEVREMKNMVVKKQKYEEAAKLRDDEKRIE
KDLAAAQEQWEEDSKNNRIEVTEDNVADVVSMMTGIPVNRIAQTESNKLAKLPELIQNKVIGQNDAVLKIARSIQRNRAG
LKDPNKPIGSFIFLGQTGVGKTQLAKVLAKELFDSEDALVRIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRKP
YCVVLLDEIEKAHPDVFNMMLQVLDDGYLTDSLGRKIDFKNTIIIMTSNVGARQLKDFGQGVGFGTAARTAQADENSKSI
IENALKKTFAPEFLNRIDDVIVFNALEKADIDLIIEIELKKLYSRIAELGYKLSLTDKAKAFIAEKGFDKQFGARPLKRA
IQKYVEDLLAEEIITSKIHSGDEIMMDLKDDSQELSVEIHKAEEPTNQ
>Mature_848_residues
MDDNFSPRVKDVITYSKEEALRLGHDFIGTEHLMLGILRDGNGKAIHILNNLAVDLDHLRRKVEILSPANHSVEVNTEKK
NLHLTRQAERALKTTFLEAKVFQSSSISTAHLLLCILRNENDPTTKLLNKLKIDYDVAKEQYLNMTPNEEEFLENLPRNE
SYNDDSGQDDSLKESSFNNPANKSNKKSKTPVLDNFGRDLTEMAEEGKLDPVVGREKEIERVSQILSRRKKNNPLLIGEP
GVGKSAITEGLALRIIQKKVSRILFHKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEKNDDIILFIDEIHTIVGAGGA
TGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALERRFQKVIVEPTSVEETIAILNNVKDKYEDHHNVTYTQEA
IEACVKLTDRYMSERFLPDKAIDALDEAGSRVHITNIDVPKQILDLERQLEEVREMKNMVVKKQKYEEAAKLRDDEKRIE
KDLAAAQEQWEEDSKNNRIEVTEDNVADVVSMMTGIPVNRIAQTESNKLAKLPELIQNKVIGQNDAVLKIARSIQRNRAG
LKDPNKPIGSFIFLGQTGVGKTQLAKVLAKELFDSEDALVRIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRKP
YCVVLLDEIEKAHPDVFNMMLQVLDDGYLTDSLGRKIDFKNTIIIMTSNVGARQLKDFGQGVGFGTAARTAQADENSKSI
IENALKKTFAPEFLNRIDDVIVFNALEKADIDLIIEIELKKLYSRIAELGYKLSLTDKAKAFIAEKGFDKQFGARPLKRA
IQKYVEDLLAEEIITSKIHSGDEIMMDLKDDSQELSVEIHKAEEPTNQ

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=336, Percent_Identity=33.3333333333333, Blast_Score=182, Evalue=8e-46,
Organism=Escherichia coli, GI1788943, Length=884, Percent_Identity=42.7601809954751, Blast_Score=661, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=826, Percent_Identity=36.4406779661017, Blast_Score=522, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6320464, Length=714, Percent_Identity=42.8571428571429, Blast_Score=554, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6323002, Length=716, Percent_Identity=39.5251396648045, Blast_Score=493, Evalue=1e-140,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 95643; Mature: 95643

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50151 UVR ; PS00675 SIGMA54_INTERACT_1 ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNFSPRVKDVITYSKEEALRLGHDFIGTEHLMLGILRDGNGKAIHILNNLAVDLDHLR
CCCCCCCHHHHHHHHCHHHHHHHHHHHHCHHHHHEEEEECCCCCEEEEHHHHHHHHHHHH
RKVEILSPANHSVEVNTEKKNLHLTRQAERALKTTFLEAKVFQSSSISTAHLLLCILRNE
HHHHHCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
NDPTTKLLNKLKIDYDVAKEQYLNMTPNEEEFLENLPRNESYNDDSGQDDSLKESSFNNP
CCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCC
ANKSNKKSKTPVLDNFGRDLTEMAEEGKLDPVVGREKEIERVSQILSRRKKNNPLLIGEP
CCCCCCCCCCCCHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECC
GVGKSAITEGLALRIIQKKVSRILFHKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NDDIILFIDEIHTIVGAGGATGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGAL
CCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHH
ERRFQKVIVEPTSVEETIAILNNVKDKYEDHHNVTYTQEAIEACVKLTDRYMSERFLPDK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
AIDALDEAGSRVHITNIDVPKQILDLERQLEEVREMKNMVVKKQKYEEAAKLRDDEKRIE
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KDLAAAQEQWEEDSKNNRIEVTEDNVADVVSMMTGIPVNRIAQTESNKLAKLPELIQNKV
HHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHC
IGQNDAVLKIARSIQRNRAGLKDPNKPIGSFIFLGQTGVGKTQLAKVLAKELFDSEDALV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEE
RIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRKPYCVVLLDEIEKAHPDVFNMM
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHHCCHHHHHH
LQVLDDGYLTDSLGRKIDFKNTIIIMTSNVGARQLKDFGQGVGFGTAARTAQADENSKSI
HHHHCCCCHHHHHCCEECCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHCCCCCCCHHHH
IENALKKTFAPEFLNRIDDVIVFNALEKADIDLIIEIELKKLYSRIAELGYKLSLTDKAK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCEEEECHHHH
AFIAEKGFDKQFGARPLKRAIQKYVEDLLAEEIITSKIHSGDEIMMDLKDDSQELSVEIH
HHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEE
KAEEPTNQ
ECCCCCCC
>Mature Secondary Structure
MDDNFSPRVKDVITYSKEEALRLGHDFIGTEHLMLGILRDGNGKAIHILNNLAVDLDHLR
CCCCCCCHHHHHHHHCHHHHHHHHHHHHCHHHHHEEEEECCCCCEEEEHHHHHHHHHHHH
RKVEILSPANHSVEVNTEKKNLHLTRQAERALKTTFLEAKVFQSSSISTAHLLLCILRNE
HHHHHCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
NDPTTKLLNKLKIDYDVAKEQYLNMTPNEEEFLENLPRNESYNDDSGQDDSLKESSFNNP
CCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCC
ANKSNKKSKTPVLDNFGRDLTEMAEEGKLDPVVGREKEIERVSQILSRRKKNNPLLIGEP
CCCCCCCCCCCCHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECC
GVGKSAITEGLALRIIQKKVSRILFHKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
NDDIILFIDEIHTIVGAGGATGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGAL
CCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHH
ERRFQKVIVEPTSVEETIAILNNVKDKYEDHHNVTYTQEAIEACVKLTDRYMSERFLPDK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
AIDALDEAGSRVHITNIDVPKQILDLERQLEEVREMKNMVVKKQKYEEAAKLRDDEKRIE
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KDLAAAQEQWEEDSKNNRIEVTEDNVADVVSMMTGIPVNRIAQTESNKLAKLPELIQNKV
HHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHC
IGQNDAVLKIARSIQRNRAGLKDPNKPIGSFIFLGQTGVGKTQLAKVLAKELFDSEDALV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEE
RIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRKPYCVVLLDEIEKAHPDVFNMM
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHHCCHHHHHH
LQVLDDGYLTDSLGRKIDFKNTIIIMTSNVGARQLKDFGQGVGFGTAARTAQADENSKSI
HHHHCCCCHHHHHCCEECCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHCCCCCCCHHHH
IENALKKTFAPEFLNRIDDVIVFNALEKADIDLIIEIELKKLYSRIAELGYKLSLTDKAK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCEEEECHHHH
AFIAEKGFDKQFGARPLKRAIQKYVEDLLAEEIITSKIHSGDEIMMDLKDDSQELSVEIH
HHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEE
KAEEPTNQ
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]