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The map label for this gene is 146284591

Identifier: 146284591

GI number: 146284591

Start: 91470

End: 93563

Strand: Direct

Name: 146284591

Synonym: Ent638_4265

Alternate gene names: NA

Gene position: 91470-93563 (Clockwise)

Preceding gene: 146284590

Following gene: 146284592

Centisome position: 57.98

GC content: 54.2

Gene sequence:

>2094_bases
TTGAGTAATAACACCCCTCTTTATCCGCAACAGCTAACGGTTCATCAGGCTATGGAACTGGCGAATGCACACTGGAATGC
GGGTCAGGCAGCACAGGCAGAGCAGCTTTGTTTGCGTGTTCTTCAGGTTGCCCCTTCGCAGCCCGATGCTCTTAATCTTT
TAGGCTTGATGATGCATGCCTACGGCAAGATGGATCTGGCCCTCGACTACATACGTAAAGCTGGGCAGTCGCCGGGTGCA
CCGGCGATAGTGTTCAGCAATCTGGCCGAGCTTTGCCGCCAAAGGGGGTTATTACAGGAAGCAGAACAAGCCGCCCGGCG
AGCAGTAGAACAAGAGCCGCAACTGGCTTTGGCATGGAATAACCTTGGCATCATTTTGCAGGAGGCAGGGAAATTTAAGG
CCAGCCTTGAGTGCCTGCAATACGTGGCATCGCTGCAACCAGACAATGCTGAGGTGCACAACAATCTGGCCAATACCTGG
AAGCGCCTGGGTGACTTGCAACGCGCTCAGGAAAGTTACCAGCGTGCGCTGAATTTACGACCTGATTACGCAGAGGTCTA
CAGTAATCTCGCCTCGCTGTTAAGTGAGTTGGGATGTATTGATGAGGCTGCGGCTTCTGCCAGACAGGCAATAGATATCA
ACCCGCAACTGGCTGATGCCTACCTGAATCTGGCGGATATTGAATTGTCGCGTATGCGCTACGCAGAAGCATCGCATTGG
GTTAAAGCACTTCTGGAGTTTTCGCCCCGACATGCGGGGGCGCTTATCACTCTTGCCCATATCATGATAGCTAATGAGCA
TTATGAAGAGGCGGCCTTCGAAGCACGCAAGGCGCTGGCCATCGCCCCGGACAGGGCTAATGCGCATATGATCCTGGGTA
AAGCATTGCAGGCGCTTGGGCAGTATGAAGACGCAGACAGAGCTTATAGTAAGGCAGCGGTATTACCAGGCACGGTTGCT
GAAGAGGCCCTGATTGCGCGCGCGGTTTTGCTGATGGAAACCGGTGATAAGCAAGCCGCTACGGCGGCGTTTGAACAGGC
CTTGAAACGTTTTCCAGATTCAGCGCGGATTGTCGCTGCGCGTTGTGACAATAAGTTCTATCGTGCCGGCGACCCTGACA
TTGATGTGATGGAGAGCGCATTGGTCAGCGAGCCAACGCCTCCACTTAATGAAAAAATGATGCTGCATTTTTCGCTGGGC
AAAGCCTGGCTTGATGTTAGCGATTCCGAACGCGCATTTTTTCATCTGAATCAGGGCAACGCCCTCAAGCGTGCCTCTTT
TCATTACGATGCCGCTCAAACCCGTGCGTGGGTGAACAACATTGCGGAGATTTTCACGCCAGCCTTGATGGCGCAGTTCA
ACAACGCGGGCACGGCTTCTGAGCGGTCGGTCTTTGTCGTCGGGATGCCTCGCTCTGGCACCACTCTGGTTGAGCAGATT
CTGGCCTCACATCCCGGTGTTTACGGTGCAGGGGAGTTGCGTGCACTGGATCGGGCTGTGGCACGCGCAGGCCGATTCCC
CGATGATGTACCACGCTGGAATAATGCTGACTTTGCTCGTATTGGGACAGACTATCTGGAGCAGGTGAGTCACCTGGCAC
CGGAGGCATTGCGCGTGATCGACAAGCTGCCTGCGAACTTCTTTTATGCCGGACTGATTCCACTTCTTCTGCCTGGCGCG
CGCATCATCCATTGCCGCCGTAACCCTGTTGATACGTGCTTATCCTGTTACAGCAAGCTGTTTGCTGGCGAACAGACATT
CGCTTATCAACTGGATGAGCTGGGTCAGTTCTACCGTGATTATGAGGCGTTGATGGCCCATTTTCGCCAGATACTGCCAG
CTGACAGCTTCATTGAAGTCGACTATGAGACTGTGGTCGACGATCTTGAAGGGCAGGCGCGGCGCCTGATTGATTTTATC
GCTCTTCCCTGGGACGACGCCTGTCTGACCTTCCACGAAACTCGCCGTATCGTGCGCACGGCAAGCGTTGCCCAGGTGCG
TCAGCCGATCTATACCTCCTCTAAAGGACGCTGGCAACAACATGCTGCACACCTCGGTCCCTTGTTAAAAGCACTGGGGA
TGGAGCAGAAATGA

Upstream 100 bases:

>100_bases
GAGCAATTCAGGTTGAAGCGAAGCACAACGTTTAGAACGCTTTATCGGTCCGCCAGACTACGTATTCAGCGGGCGTTTAC
TTGTTTATCTGAGGAATATC

Downstream 100 bases:

>100_bases
ACCCTGAACCGACAGACAACCAAACCCTTTTCCAGCAGGTTGATGAACTTCTGAAAGCTGAACGCTGGGCACAGGCCGAA
GCGGTGCTGAGTCAAGCGCT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MSNNTPLYPQQLTVHQAMELANAHWNAGQAAQAEQLCLRVLQVAPSQPDALNLLGLMMHAYGKMDLALDYIRKAGQSPGA
PAIVFSNLAELCRQRGLLQEAEQAARRAVEQEPQLALAWNNLGIILQEAGKFKASLECLQYVASLQPDNAEVHNNLANTW
KRLGDLQRAQESYQRALNLRPDYAEVYSNLASLLSELGCIDEAAASARQAIDINPQLADAYLNLADIELSRMRYAEASHW
VKALLEFSPRHAGALITLAHIMIANEHYEEAAFEARKALAIAPDRANAHMILGKALQALGQYEDADRAYSKAAVLPGTVA
EEALIARAVLLMETGDKQAATAAFEQALKRFPDSARIVAARCDNKFYRAGDPDIDVMESALVSEPTPPLNEKMMLHFSLG
KAWLDVSDSERAFFHLNQGNALKRASFHYDAAQTRAWVNNIAEIFTPALMAQFNNAGTASERSVFVVGMPRSGTTLVEQI
LASHPGVYGAGELRALDRAVARAGRFPDDVPRWNNADFARIGTDYLEQVSHLAPEALRVIDKLPANFFYAGLIPLLLPGA
RIIHCRRNPVDTCLSCYSKLFAGEQTFAYQLDELGQFYRDYEALMAHFRQILPADSFIEVDYETVVDDLEGQARRLIDFI
ALPWDDACLTFHETRRIVRTASVAQVRQPIYTSSKGRWQQHAAHLGPLLKALGMEQK

Sequences:

>Translated_697_residues
MSNNTPLYPQQLTVHQAMELANAHWNAGQAAQAEQLCLRVLQVAPSQPDALNLLGLMMHAYGKMDLALDYIRKAGQSPGA
PAIVFSNLAELCRQRGLLQEAEQAARRAVEQEPQLALAWNNLGIILQEAGKFKASLECLQYVASLQPDNAEVHNNLANTW
KRLGDLQRAQESYQRALNLRPDYAEVYSNLASLLSELGCIDEAAASARQAIDINPQLADAYLNLADIELSRMRYAEASHW
VKALLEFSPRHAGALITLAHIMIANEHYEEAAFEARKALAIAPDRANAHMILGKALQALGQYEDADRAYSKAAVLPGTVA
EEALIARAVLLMETGDKQAATAAFEQALKRFPDSARIVAARCDNKFYRAGDPDIDVMESALVSEPTPPLNEKMMLHFSLG
KAWLDVSDSERAFFHLNQGNALKRASFHYDAAQTRAWVNNIAEIFTPALMAQFNNAGTASERSVFVVGMPRSGTTLVEQI
LASHPGVYGAGELRALDRAVARAGRFPDDVPRWNNADFARIGTDYLEQVSHLAPEALRVIDKLPANFFYAGLIPLLLPGA
RIIHCRRNPVDTCLSCYSKLFAGEQTFAYQLDELGQFYRDYEALMAHFRQILPADSFIEVDYETVVDDLEGQARRLIDFI
ALPWDDACLTFHETRRIVRTASVAQVRQPIYTSSKGRWQQHAAHLGPLLKALGMEQK
>Mature_696_residues
SNNTPLYPQQLTVHQAMELANAHWNAGQAAQAEQLCLRVLQVAPSQPDALNLLGLMMHAYGKMDLALDYIRKAGQSPGAP
AIVFSNLAELCRQRGLLQEAEQAARRAVEQEPQLALAWNNLGIILQEAGKFKASLECLQYVASLQPDNAEVHNNLANTWK
RLGDLQRAQESYQRALNLRPDYAEVYSNLASLLSELGCIDEAAASARQAIDINPQLADAYLNLADIELSRMRYAEASHWV
KALLEFSPRHAGALITLAHIMIANEHYEEAAFEARKALAIAPDRANAHMILGKALQALGQYEDADRAYSKAAVLPGTVAE
EALIARAVLLMETGDKQAATAAFEQALKRFPDSARIVAARCDNKFYRAGDPDIDVMESALVSEPTPPLNEKMMLHFSLGK
AWLDVSDSERAFFHLNQGNALKRASFHYDAAQTRAWVNNIAEIFTPALMAQFNNAGTASERSVFVVGMPRSGTTLVEQIL
ASHPGVYGAGELRALDRAVARAGRFPDDVPRWNNADFARIGTDYLEQVSHLAPEALRVIDKLPANFFYAGLIPLLLPGAR
IIHCRRNPVDTCLSCYSKLFAGEQTFAYQLDELGQFYRDYEALMAHFRQILPADSFIEVDYETVVDDLEGQARRLIDFIA
LPWDDACLTFHETRRIVRTASVAQVRQPIYTSSKGRWQQHAAHLGPLLKALGMEQK

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=333, Percent_Identity=31.8318318318318, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI32307148, Length=333, Percent_Identity=31.8318318318318, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI118766330, Length=250, Percent_Identity=25.2, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI118766328, Length=250, Percent_Identity=25.2, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI301336134, Length=298, Percent_Identity=24.1610738255034, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI83415184, Length=298, Percent_Identity=24.1610738255034, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI224809432, Length=347, Percent_Identity=23.9193083573487, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=333, Percent_Identity=31.8318318318318, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI115532690, Length=333, Percent_Identity=31.8318318318318, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI193210476, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647755, Length=333, Percent_Identity=30.9309309309309, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24585827, Length=333, Percent_Identity=30.9309309309309, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24585829, Length=333, Percent_Identity=30.9309309309309, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19920486, Length=333, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI161076610, Length=333, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647123, Length=231, Percent_Identity=25.974025974026, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364285, Length=342, Percent_Identity=26.9005847953216, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581187, Length=342, Percent_Identity=26.9005847953216, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000863
- InterPro:   IPR001440
- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00685 Sulfotransfer_1; PF00515 TPR_1; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 77232; Mature: 77100

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNTPLYPQQLTVHQAMELANAHWNAGQAAQAEQLCLRVLQVAPSQPDALNLLGLMMHA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YGKMDLALDYIRKAGQSPGAPAIVFSNLAELCRQRGLLQEAEQAARRAVEQEPQLALAWN
HCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEC
NLGIILQEAGKFKASLECLQYVASLQPDNAEVHNNLANTWKRLGDLQRAQESYQRALNLR
CCCCEEHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDYAEVYSNLASLLSELGCIDEAAASARQAIDINPQLADAYLNLADIELSRMRYAEASHW
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKALLEFSPRHAGALITLAHIMIANEHYEEAAFEARKALAIAPDRANAHMILGKALQALG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
QYEDADRAYSKAAVLPGTVAEEALIARAVLLMETGDKQAATAAFEQALKRFPDSARIVAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEE
RCDNKFYRAGDPDIDVMESALVSEPTPPLNEKMMLHFSLGKAWLDVSDSERAFFHLNQGN
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHCCCCCCCCEEEEECCCC
ALKRASFHYDAAQTRAWVNNIAEIFTPALMAQFNNAGTASERSVFVVGMPRSGTTLVEQI
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHH
LASHPGVYGAGELRALDRAVARAGRFPDDVPRWNNADFARIGTDYLEQVSHLAPEALRVI
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHCHHHHHHH
DKLPANFFYAGLIPLLLPGARIIHCRRNPVDTCLSCYSKLFAGEQTFAYQLDELGQFYRD
HHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YEALMAHFRQILPADSFIEVDYETVVDDLEGQARRLIDFIALPWDDACLTFHETRRIVRT
HHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASVAQVRQPIYTSSKGRWQQHAAHLGPLLKALGMEQK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNNTPLYPQQLTVHQAMELANAHWNAGQAAQAEQLCLRVLQVAPSQPDALNLLGLMMHA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YGKMDLALDYIRKAGQSPGAPAIVFSNLAELCRQRGLLQEAEQAARRAVEQEPQLALAWN
HCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEC
NLGIILQEAGKFKASLECLQYVASLQPDNAEVHNNLANTWKRLGDLQRAQESYQRALNLR
CCCCEEHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDYAEVYSNLASLLSELGCIDEAAASARQAIDINPQLADAYLNLADIELSRMRYAEASHW
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VKALLEFSPRHAGALITLAHIMIANEHYEEAAFEARKALAIAPDRANAHMILGKALQALG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
QYEDADRAYSKAAVLPGTVAEEALIARAVLLMETGDKQAATAAFEQALKRFPDSARIVAA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEE
RCDNKFYRAGDPDIDVMESALVSEPTPPLNEKMMLHFSLGKAWLDVSDSERAFFHLNQGN
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHCCCCCCCCEEEEECCCC
ALKRASFHYDAAQTRAWVNNIAEIFTPALMAQFNNAGTASERSVFVVGMPRSGTTLVEQI
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHH
LASHPGVYGAGELRALDRAVARAGRFPDDVPRWNNADFARIGTDYLEQVSHLAPEALRVI
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHCHHHHHHH
DKLPANFFYAGLIPLLLPGARIIHCRRNPVDTCLSCYSKLFAGEQTFAYQLDELGQFYRD
HHCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YEALMAHFRQILPADSFIEVDYETVVDDLEGQARRLIDFIALPWDDACLTFHETRRIVRT
HHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASVAQVRQPIYTSSKGRWQQHAAHLGPLLKALGMEQK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]