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The map label for this gene is relB

Identifier: 146284552

GI number: 146284552

Start: 38858

End: 39097

Strand: Direct

Name: relB

Synonym: Ent638_4226

Alternate gene names: 146284552

Gene position: 38858-39097 (Clockwise)

Preceding gene: 146284550

Following gene: 146284553

Centisome position: 24.63

GC content: 48.33

Gene sequence:

>240_bases
ATGGGTAGCATCAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCTGCGCTCGAAAAAATGGGTGTAACTCC
CTCTGAAGCGCTTCGCCTCATGCTTGAATATATTGCTGACAATGAACGTTTGCCGTTCAAACAGACACTCCTGAGTGATG
AGGATGCTGAGCTCGTGGAGATAGTGAAAGAACGTCTTCGCAATCCTAAGCCAGTACGTGTGACGCTGGATGAGCTCTGA

Upstream 100 bases:

>100_bases
CCTTCTGACGTCTTGTTTTCTGGCTTCCTTCGTGACTTGCCCTAAGCATGTTGTAGTGCGATACTTGTAATGACATTTGT
ATTTACAAGAGGTGTGAGAC

Downstream 100 bases:

>100_bases
TGGCATATTTTCTGGATTTTGACGAGCGTGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAAA
AAGAAGCTGGCTGAAGTGCT

Product: bifunctional antitoxin/transcriptional repressor RelB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL

Sequences:

>Translated_79_residues
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL
>Mature_78_residues
GSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL

Specific function: Counteracts the effect of relE by means of direct protein-protein interaction, enabling the reversion of translation inhibition. Also acts as an autorepressor of relBE transcription. Increased transcription rate of relBE and activation of relE is consiste

COG id: COG3077

COG function: function code L; DNA-damage-inducible protein J

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787847, Length=79, Percent_Identity=100, Blast_Score=156, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RELB_ECOLI (P0C079)

Other databases:

- EMBL:   X02405
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   A22830
- RefSeq:   AP_002186.1
- RefSeq:   NP_416082.1
- PDB:   2K29
- PDB:   2KC8
- PDBsum:   2K29
- PDBsum:   2KC8
- ProteinModelPortal:   P0C079
- SMR:   P0C079
- DIP:   DIP-48258N
- STRING:   P0C079
- EnsemblBacteria:   EBESCT00000000676
- EnsemblBacteria:   EBESCT00000015556
- GeneID:   948308
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1556
- KEGG:   eco:b1564
- EchoBASE:   EB0829
- EcoGene:   EG10836
- eggNOG:   COG3077
- GeneTree:   EBGT00050000012035
- HOGENOM:   HBG519852
- OMA:   MSAVTFR
- ProtClustDB:   PRK11235
- BioCyc:   EcoCyc:EG10836-MONOMER
- Genevestigator:   P0C079
- GO:   GO:0006350
- InterPro:   IPR007337
- TIGRFAMs:   TIGR02384

Pfam domain/function: PF04221 RelB

EC number: NA

Molecular weight: Translated: 9072; Mature: 8940

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVE
CCCCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHH
IVKERLRNPKPVRVTLDEL
HHHHHCCCCCCEEEEECCC
>Mature Secondary Structure 
GSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVE
CCCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHH
IVKERLRNPKPVRVTLDEL
HHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2990907; 9097039; 9278503; 9767574