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The map label for this gene is ptsJ [H]

Identifier: 146284539

GI number: 146284539

Start: 23246

End: 24544

Strand: Direct

Name: ptsJ [H]

Synonym: Ent638_4213

Alternate gene names: 146284539

Gene position: 23246-24544 (Clockwise)

Preceding gene: 146284536

Following gene: 146284540

Centisome position: 14.74

GC content: 47.58

Gene sequence:

>1299_bases
ATGAACATTAACGGTAAAACAGCGGGTGATATTTTCGAACAGATTCGCGCAATGATTCAGGCTGGCGAACTTGTTCCCGG
CATGATGCTTCCCACGCTTCGTGAACTTGCAGGTGAATTGGGTATCAATCGTAATACGGTTGCCCTGGCTTATAAGCGAC
TTACGGACGCAGGTTTTGTCATATCCAGAGGCCGAAATGGAACTATTGTACGTGAACACATTATGCTCACTGATATTGAA
GGTAGTGCGTCTAACCTTGTGCTTCGTGACCTCGCCAGCGGCAACCCTGCAGTCACACTTCTGCCTTCAATGAGCCAACT
TGCCGTGCATATCCAAAACACGCCGGGTCTGTACGGTGAAACCGTGATCCGCCCTGAACTTGAGGCTCTGGGGCTTGAAT
GGTTAAAACAAGATATAGGATCACCTTTTGATTTAAATCTGACTAACGGTGCTGTTGATGCTATTGAAAAGGTACTTACC
AGCTATTTGATTGCTGGAGATCGTGTGGCTGTTGAAGACCCTTGCTTCCTCAGTAGCATCAGCACTCTGCGCCATAACCG
CTTTCAGGTTGCTCCTGTGGAAATAGATGTCGAAGGGATGAAAATTGAGTCGCTTTCACGGCAGCTTTCTGCTGGCGTGA
AAGCGGTGATTATTACTCCACGTGCCCACAATCCTACCGGTTTTAGCCTCAGTTTTAAGCGTGCTGAAGGTATTCGTACT
CTCCTGGCTAGTCATCCTCACGTTCTGGTGATAGTGGATGATCACTTTTCATTGCTCTCAACACATGACTACTACCACAT
TGTTCCGGGAAATACCCGCAACTGGGTACTCATCCGTTCCATGTCAAAGAGCTTGGGACCTGATTTACGTATGGCCTTTG
TCGCAAGCGATGCAGATACCTCACAGCGCTTGCGCCTGCGCCTGAATTCGGGGACTAACTGGGTAAGTCATATTTTGCAG
GATATGGTTGTTGGTCATATGCATTCATCTGGCTTCCAGAAGTCAATCTTGTCCGCACGTGAGAGTTATTTTGAAAAAAG
AGAGTTGATGGTCAATGCGCTAAAACAACATGGCGTCAAAGTTCCAGACCATCATGATGGCCTCAATGTGTGGATTCCGT
TGACACAGAACAGCGCTCCAATTGTTATGCAAATGGCCCAACGGGGTTGGCTTATTCGGGGTGGGGAAGGTTTCAACCTG
AACAATTCTGGCTCCGGGGTGCGAATCACCATTTCAGATCTTGATGCAACGGAAACTAAACTAATCGCGAAATCTCTGGC
TGAGATACTGACACAATAG

Upstream 100 bases:

>100_bases
GTAGTTTGGTGCTGTTTTCTGTATTTTTCATAGCAGATAGACAAGAGCTCCGTACTCAATTAATATTGTCCTAGGCTAAA
CTTAAATTTGAACCAGGTCA

Downstream 100 bases:

>100_bases
TAATAGATTCTCGCCATATAAACGGTCTGAACAGACCTGCATATTGATAATGGAGTTATTTGTAATGCACGTACATTTCA
TCGTACATGAGGATTTTGAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNINGKTAGDIFEQIRAMIQAGELVPGMMLPTLRELAGELGINRNTVALAYKRLTDAGFVISRGRNGTIVREHIMLTDIE
GSASNLVLRDLASGNPAVTLLPSMSQLAVHIQNTPGLYGETVIRPELEALGLEWLKQDIGSPFDLNLTNGAVDAIEKVLT
SYLIAGDRVAVEDPCFLSSISTLRHNRFQVAPVEIDVEGMKIESLSRQLSAGVKAVIITPRAHNPTGFSLSFKRAEGIRT
LLASHPHVLVIVDDHFSLLSTHDYYHIVPGNTRNWVLIRSMSKSLGPDLRMAFVASDADTSQRLRLRLNSGTNWVSHILQ
DMVVGHMHSSGFQKSILSARESYFEKRELMVNALKQHGVKVPDHHDGLNVWIPLTQNSAPIVMQMAQRGWLIRGGEGFNL
NNSGSGVRITISDLDATETKLIAKSLAEILTQ

Sequences:

>Translated_432_residues
MNINGKTAGDIFEQIRAMIQAGELVPGMMLPTLRELAGELGINRNTVALAYKRLTDAGFVISRGRNGTIVREHIMLTDIE
GSASNLVLRDLASGNPAVTLLPSMSQLAVHIQNTPGLYGETVIRPELEALGLEWLKQDIGSPFDLNLTNGAVDAIEKVLT
SYLIAGDRVAVEDPCFLSSISTLRHNRFQVAPVEIDVEGMKIESLSRQLSAGVKAVIITPRAHNPTGFSLSFKRAEGIRT
LLASHPHVLVIVDDHFSLLSTHDYYHIVPGNTRNWVLIRSMSKSLGPDLRMAFVASDADTSQRLRLRLNSGTNWVSHILQ
DMVVGHMHSSGFQKSILSARESYFEKRELMVNALKQHGVKVPDHHDGLNVWIPLTQNSAPIVMQMAQRGWLIRGGEGFNL
NNSGSGVRITISDLDATETKLIAKSLAEILTQ
>Mature_432_residues
MNINGKTAGDIFEQIRAMIQAGELVPGMMLPTLRELAGELGINRNTVALAYKRLTDAGFVISRGRNGTIVREHIMLTDIE
GSASNLVLRDLASGNPAVTLLPSMSQLAVHIQNTPGLYGETVIRPELEALGLEWLKQDIGSPFDLNLTNGAVDAIEKVLT
SYLIAGDRVAVEDPCFLSSISTLRHNRFQVAPVEIDVEGMKIESLSRQLSAGVKAVIITPRAHNPTGFSLSFKRAEGIRT
LLASHPHVLVIVDDHFSLLSTHDYYHIVPGNTRNWVLIRSMSKSLGPDLRMAFVASDADTSQRLRLRLNSGTNWVSHILQ
DMVVGHMHSSGFQKSILSARESYFEKRELMVNALKQHGVKVPDHHDGLNVWIPLTQNSAPIVMQMAQRGWLIRGGEGFNL
NNSGSGVRITISDLDATETKLIAKSLAEILTQ

Specific function: Putative transcriptional regulator of the ptsHI/crr operon [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787710, Length=416, Percent_Identity=26.6826923076923, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790797, Length=317, Percent_Identity=25.8675078864353, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 47384; Mature: 47384

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINGKTAGDIFEQIRAMIQAGELVPGMMLPTLRELAGELGINRNTVALAYKRLTDAGFV
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
ISRGRNGTIVREHIMLTDIEGSASNLVLRDLASGNPAVTLLPSMSQLAVHIQNTPGLYGE
EECCCCCCEEEEEEEEEECCCCCCCEEHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCC
TVIRPELEALGLEWLKQDIGSPFDLNLTNGAVDAIEKVLTSYLIAGDRVAVEDPCFLSSI
EEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHH
STLRHNRFQVAPVEIDVEGMKIESLSRQLSAGVKAVIITPRAHNPTGFSLSFKRAEGIRT
HHHHCCCEEEEEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEHHHHHHHH
LLASHPHVLVIVDDHFSLLSTHDYYHIVPGNTRNWVLIRSMSKSLGPDLRMAFVASDADT
HHHCCCEEEEEECCCCCEEECCCEEEEECCCCCCEEEEEECHHHCCCCEEEEEEECCCCC
SQRLRLRLNSGTNWVSHILQDMVVGHMHSSGFQKSILSARESYFEKRELMVNALKQHGVK
CEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPDHHDGLNVWIPLTQNSAPIVMQMAQRGWLIRGGEGFNLNNSGSGVRITISDLDATETK
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCHHHH
LIAKSLAEILTQ
HHHHHHHHHHCC
>Mature Secondary Structure
MNINGKTAGDIFEQIRAMIQAGELVPGMMLPTLRELAGELGINRNTVALAYKRLTDAGFV
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
ISRGRNGTIVREHIMLTDIEGSASNLVLRDLASGNPAVTLLPSMSQLAVHIQNTPGLYGE
EECCCCCCEEEEEEEEEECCCCCCCEEHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCC
TVIRPELEALGLEWLKQDIGSPFDLNLTNGAVDAIEKVLTSYLIAGDRVAVEDPCFLSSI
EEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHH
STLRHNRFQVAPVEIDVEGMKIESLSRQLSAGVKAVIITPRAHNPTGFSLSFKRAEGIRT
HHHHCCCEEEEEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEHHHHHHHH
LLASHPHVLVIVDDHFSLLSTHDYYHIVPGNTRNWVLIRSMSKSLGPDLRMAFVASDADT
HHHCCCEEEEEECCCCCEEECCCEEEEECCCCCCEEEEEECHHHCCCCEEEEEEECCCCC
SQRLRLRLNSGTNWVSHILQDMVVGHMHSSGFQKSILSARESYFEKRELMVNALKQHGVK
CEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPDHHDGLNVWIPLTQNSAPIVMQMAQRGWLIRGGEGFNLNNSGSGVRITISDLDATETK
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCHHHH
LIAKSLAEILTQ
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7612925; 11677609 [H]