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The map label for this gene is asnC [H]

Identifier: 145299800

GI number: 145299800

Start: 3105598

End: 3107043

Strand: Direct

Name: asnC [H]

Synonym: ASA_2881

Alternate gene names: 145299800

Gene position: 3105598-3107043 (Clockwise)

Preceding gene: 145299798

Following gene: 145299801

Centisome position: 66.04

GC content: 58.51

Gene sequence:

>1446_bases
GTGTTTCAAATAGCGCTGCAAGAACAAGCTGGAGACAATATTTCGATGACGCACGCATCCGTAGTAGATGTGCTGACCGG
TAAATATGCGGTTGGCACCACCCAGACAGTAAAAGGGTGGATCCGGACTCGCCGTGATTCCAAGGCGGGGATCTCATTTT
TGGCCGTATCCGACGGCTCCTGTTTCCATCCGGTACAGGCAGTTGTCCCCAATACCTTGGCCAATTATGAGAATGAAGTG
CTGCGTCTGACCACAGCTTGCTCCGTGGAAGTGAGCGGTGTGGTTGCCGCCTCCCAGGGCAGCGGTCAGGCTTTCGAACT
GCAAGCCACCGACGTCAAGGTCGTAGGCTGGGTCGAAGATCCGGACACCTACCCCATGGCCGCCAAGCGCCACAGCATAG
AGTACCTGCGTGAACAGGCCCACCTGCGTCCGCGCACCAACATAGTCGGCGCCGTGACCCGGGTGCGCAACTGCCTGGCC
CAGGCCATCCACCGCTTCTTCCATGAAGAGGGTTATCTGTGGATTGCGGCTCCGCTCATCACCGCCTCTGACACCGAAGG
TGCCGGCGAGATGTTCCGCGTCTCCACCCTGGATCTGGAAAACCTGCCGCGCACCGACGCTGGCAAGGTCGATTACGACA
AGGACTTCTTCGGCAAGGAGACCTTCCTGACCGTATCTGGCCAGCTCAACGTCGAAACCTACGCCTGTGCCCTCTCCAAG
GTCTACACCTTCGGGCCCACCTTCCGCGCCGAGAATTCCAACACCAGCCGCCATTTGGCCGAGTTCTGGATGGTTGAGCC
GGAAATTGCCTTCGCCAACCTGGACGATAACGCCGCCCTGGCCGAAGCCATGCTCAAATACGTCTTCAACGCCGTACTGG
CAGAGCGCCGCGACGATCTGGAGTTCTTTGCCCAGCACGTCGACAAGGATGCCATCGGTCGTCTGGAACGCTTCGTCTCC
TCCGACTTTGCCCAGATCGACTACACAGATGCCATCGAAGTGCTGAAAAACTGTGGCAAGAAGTTCGAGTTCCCTGTCTC
CTGGGGCATCGATCTCTCCTCCGAGCACGAGCGCTATCTGGCCGAGGAGCACTTCAAGTCTCCTGTGGTGGTGAAGAACT
ACCCGAAAGACATCAAAGCCTTCTACATGCGTCTCAACGATGACGGCAAGACAGTTGCCGCCATGGACGTATTGGCACCG
GGGATCGGCGAGATCATCGGTGGTGCCCAGCGTGAAGAGCGCCTCGAGGTACTCGATCAGCGCATGGCCGAGATGGGTCT
GAACAAGGAAGATTACTGGTGGTATCGCGATCTGCGCCGCTTCGGCACAGTCCCGCACGCCGGTTTCGGCCTCGGTTTCG
AGCGTCTGGTAGTCTATGTGACTGGTATGGGCAACGTCCGTGACGTTATCCCCTTCCCCCGTACACCCCGTACCGCCGAA
TTCTGA

Upstream 100 bases:

>100_bases
CCAGAGTCCGACATTTTTGCTTGTTTATCAAACCCGCGCGGGTAAGATTGTCGGCTTAGTCTGCCATGATGGGCCAGTGA
ATGCCCGGGCCAGACCCCTA

Downstream 100 bases:

>100_bases
TACGGCCCTTTGCCGACAAAGCCGACCCCAGGGTCGGCTTTTTGTTGCCCGCACCACGGCATTCGCCCCTCGCAGCCACC
ACAATTAATCACACTTCCCC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MFQIALQEQAGDNISMTHASVVDVLTGKYAVGTTQTVKGWIRTRRDSKAGISFLAVSDGSCFHPVQAVVPNTLANYENEV
LRLTTACSVEVSGVVAASQGSGQAFELQATDVKVVGWVEDPDTYPMAAKRHSIEYLREQAHLRPRTNIVGAVTRVRNCLA
QAIHRFFHEEGYLWIAAPLITASDTEGAGEMFRVSTLDLENLPRTDAGKVDYDKDFFGKETFLTVSGQLNVETYACALSK
VYTFGPTFRAENSNTSRHLAEFWMVEPEIAFANLDDNAALAEAMLKYVFNAVLAERRDDLEFFAQHVDKDAIGRLERFVS
SDFAQIDYTDAIEVLKNCGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAP
GIGEIIGGAQREERLEVLDQRMAEMGLNKEDYWWYRDLRRFGTVPHAGFGLGFERLVVYVTGMGNVRDVIPFPRTPRTAE
F

Sequences:

>Translated_481_residues
MFQIALQEQAGDNISMTHASVVDVLTGKYAVGTTQTVKGWIRTRRDSKAGISFLAVSDGSCFHPVQAVVPNTLANYENEV
LRLTTACSVEVSGVVAASQGSGQAFELQATDVKVVGWVEDPDTYPMAAKRHSIEYLREQAHLRPRTNIVGAVTRVRNCLA
QAIHRFFHEEGYLWIAAPLITASDTEGAGEMFRVSTLDLENLPRTDAGKVDYDKDFFGKETFLTVSGQLNVETYACALSK
VYTFGPTFRAENSNTSRHLAEFWMVEPEIAFANLDDNAALAEAMLKYVFNAVLAERRDDLEFFAQHVDKDAIGRLERFVS
SDFAQIDYTDAIEVLKNCGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAP
GIGEIIGGAQREERLEVLDQRMAEMGLNKEDYWWYRDLRRFGTVPHAGFGLGFERLVVYVTGMGNVRDVIPFPRTPRTAE
F
>Mature_481_residues
MFQIALQEQAGDNISMTHASVVDVLTGKYAVGTTQTVKGWIRTRRDSKAGISFLAVSDGSCFHPVQAVVPNTLANYENEV
LRLTTACSVEVSGVVAASQGSGQAFELQATDVKVVGWVEDPDTYPMAAKRHSIEYLREQAHLRPRTNIVGAVTRVRNCLA
QAIHRFFHEEGYLWIAAPLITASDTEGAGEMFRVSTLDLENLPRTDAGKVDYDKDFFGKETFLTVSGQLNVETYACALSK
VYTFGPTFRAENSNTSRHLAEFWMVEPEIAFANLDDNAALAEAMLKYVFNAVLAERRDDLEFFAQHVDKDAIGRLERFVS
SDFAQIDYTDAIEVLKNCGKKFEFPVSWGIDLSSEHERYLAEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAP
GIGEIIGGAQREERLEVLDQRMAEMGLNKEDYWWYRDLRRFGTVPHAGFGLGFERLVVYVTGMGNVRDVIPFPRTPRTAE
F

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=465, Percent_Identity=43.4408602150538, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI4758762, Length=460, Percent_Identity=27.8260869565217, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI45439306, Length=344, Percent_Identity=29.6511627906977, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=79.3991416309013, Blast_Score=798, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=364, Percent_Identity=22.5274725274725, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=434, Percent_Identity=31.5668202764977, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=28.8248337028825, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17551876, Length=345, Percent_Identity=26.9565217391304, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=467, Percent_Identity=36.1884368308351, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6321807, Length=465, Percent_Identity=29.4623655913978, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=354, Percent_Identity=27.4011299435028, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19922416, Length=453, Percent_Identity=35.9823399558499, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19921528, Length=474, Percent_Identity=27.4261603375527, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI17136276, Length=342, Percent_Identity=27.4853801169591, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53883; Mature: 53883

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQIALQEQAGDNISMTHASVVDVLTGKYAVGTTQTVKGWIRTRRDSKAGISFLAVSDGS
CEEEEEECCCCCCEEEHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCEEEEEECCCC
CFHPVQAVVPNTLANYENEVLRLTTACSVEVSGVVAASQGSGQAFELQATDVKVVGWVED
CCCHHHHHHCHHHHHCCCCEEEEEEECEEEEEEEEEECCCCCCEEEEEECCEEEEEEECC
PDTYPMAAKRHSIEYLREQAHLRPRTNIVGAVTRVRNCLAQAIHRFFHEEGYLWIAAPLI
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
TASDTEGAGEMFRVSTLDLENLPRTDAGKVDYDKDFFGKETFLTVSGQLNVETYACALSK
EECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
VYTFGPTFRAENSNTSRHLAEFWMVEPEIAFANLDDNAALAEAMLKYVFNAVLAERRDDL
HHHCCCCEECCCCCCHHHHHHHHEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHH
EFFAQHVDKDAIGRLERFVSSDFAQIDYTDAIEVLKNCGKKFEFPVSWGIDLSSEHERYL
HHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLEVLDQ
HHHHCCCCEEECCCCHHHEEEEEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHH
RMAEMGLNKEDYWWYRDLRRFGTVPHAGFGLGFERLVVYVTGMGNVRDVIPFPRTPRTAE
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
F
C
>Mature Secondary Structure
MFQIALQEQAGDNISMTHASVVDVLTGKYAVGTTQTVKGWIRTRRDSKAGISFLAVSDGS
CEEEEEECCCCCCEEEHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCEEEEEECCCC
CFHPVQAVVPNTLANYENEVLRLTTACSVEVSGVVAASQGSGQAFELQATDVKVVGWVED
CCCHHHHHHCHHHHHCCCCEEEEEEECEEEEEEEEEECCCCCCEEEEEECCEEEEEEECC
PDTYPMAAKRHSIEYLREQAHLRPRTNIVGAVTRVRNCLAQAIHRFFHEEGYLWIAAPLI
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
TASDTEGAGEMFRVSTLDLENLPRTDAGKVDYDKDFFGKETFLTVSGQLNVETYACALSK
EECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
VYTFGPTFRAENSNTSRHLAEFWMVEPEIAFANLDDNAALAEAMLKYVFNAVLAERRDDL
HHHCCCCEECCCCCCHHHHHHHHEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHH
EFFAQHVDKDAIGRLERFVSSDFAQIDYTDAIEVLKNCGKKFEFPVSWGIDLSSEHERYL
HHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AEEHFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLEVLDQ
HHHHCCCCEEECCCCHHHEEEEEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHH
RMAEMGLNKEDYWWYRDLRRFGTVPHAGFGLGFERLVVYVTGMGNVRDVIPFPRTPRTAE
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA