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The map label for this gene is estR [H]

Identifier: 145299773

GI number: 145299773

Start: 3072985

End: 3073893

Strand: Direct

Name: estR [H]

Synonym: ASA_2853

Alternate gene names: 145299773

Gene position: 3072985-3073893 (Clockwise)

Preceding gene: 145299772

Following gene: 145299775

Centisome position: 65.35

GC content: 60.4

Gene sequence:

>909_bases
ATGCAACGTTGGCCCAGCCTGAAACAGCTGCAATATCTGGTCGCTCTCGACGAGCACAAGAACTTCAATCGCGCCGCCAA
GGCCTGTCATGTCAGCCAGTCCACCCTGAGTACCGGGATCCAGACGCTGGAAGACATGATGAACCTGCAACTGGTGGAGC
GGGACCACAAGAGCTTCATTATGACCCCGGTCGGCATGGAAATCGTCGAGCGAGCTCGCAATTTGCTCTCGGATGCGCGA
GATCTGATGGAGCTGGGGCAACATCAGGGCGGCGTCATGCACGGCACAGTCCGGCTCGGCTGCATCCCCACCATAGCCCC
CTTCCTGCTCAGCAAGCTGCTGCAGGAGTGCGGCAAGGCTTATCCTGAACTGGAATTGTTGCTGCGTGAAGACACCACCA
CCAACCTGCTCAAGCAACTGGAGCAGGGTCAGCTCGACTTGCTGATCCTGGCGTTGCCGGTGGAGATCGGCGGCTTCCAC
TGCAAGATGGTTGGCCAGGATCCCTTCCACATGGTGATGCCCGCCAGCATGGCGGCCGGTCTGCATACGCCGTTCGACTA
CAAGGAGCTGCCCAACCAGAGCATCTTCCTGCTGGAACGGGAGCACTGCCTCACCGAACATGCGGTCAGCGCCTGTCGGC
TGCGGGACAAGAGCAAGATAAACCCCTTTGCCGCCACCAGCCTGCACACCCTGGTACAGATGGTCGGTGCCGGGCTTGGC
ACCACCTTCCTGCCCCAGATGGCAATAGATTCCGGCATTCTCGACAACACCGACCTGGTGGCCATTCCCCTGCCGGGTGA
AAAGCCGTATCGCGAGATAGGCCTGGTGTGGCGCCCCAGCACCACCCGGGTACAGACCTTCTACAAGCTGGCCGAGCTGC
TCACTCCGCTCATAGAGCCCAAGACCTGA

Upstream 100 bases:

>100_bases
TTATTTAGAGCCAAGTCCGTCTAATTCAAGCGACAAACCCTATACCCAGTGGTAGATTAGTTAAATCAAATTAAATAGAT
AGCATTCATCGGGTTTTCCT

Downstream 100 bases:

>100_bases
GTCACATTTTGACCCACAAAAACGCCGGCAGCTTGCCGGCGTTTTCATTGGTTCAGACACATCGGCAGATCAGTTGCCGG
CCGGTGGCCCGAAGATGCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Esterase operon transcriptional regulator [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFIMTPVGMEIVERARNLLSDAR
DLMELGQHQGGVMHGTVRLGCIPTIAPFLLSKLLQECGKAYPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFH
CKMVGQDPFHMVMPASMAAGLHTPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLG
TTFLPQMAIDSGILDNTDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKLAELLTPLIEPKT

Sequences:

>Translated_302_residues
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFIMTPVGMEIVERARNLLSDAR
DLMELGQHQGGVMHGTVRLGCIPTIAPFLLSKLLQECGKAYPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFH
CKMVGQDPFHMVMPASMAAGLHTPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLG
TTFLPQMAIDSGILDNTDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKLAELLTPLIEPKT
>Mature_302_residues
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFIMTPVGMEIVERARNLLSDAR
DLMELGQHQGGVMHGTVRLGCIPTIAPFLLSKLLQECGKAYPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFH
CKMVGQDPFHMVMPASMAAGLHTPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLG
TTFLPQMAIDSGILDNTDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKLAELLTPLIEPKT

Specific function: Transcriptional regulator of the esterase operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=287, Percent_Identity=36.2369337979094, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=25.3012048192771, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787879, Length=281, Percent_Identity=27.4021352313167, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=24.6963562753036, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367136, Length=239, Percent_Identity=23.8493723849372, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=277, Percent_Identity=23.4657039711191, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788887, Length=284, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=24.901185770751, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33747; Mature: 33747

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFI
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEE
MTPVGMEIVERARNLLSDARDLMELGQHQGGVMHGTVRLGCIPTIAPFLLSKLLQECGKA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHH
YPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFHCKMVGQDPFHMVMPASMAAG
CCHHHHHHHCCCHHHHHHHHHCCCEEEEEEEEEHHHCCEEEEEECCCCCHHHHHHHHHHC
LHTPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLG
CCCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
TTFLPQMAIDSGILDNTDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKLAELLTPLIEP
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCCCEECCCCHHHHHHHHHHHHHHHHCCC
KT
CC
>Mature Secondary Structure
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFI
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEE
MTPVGMEIVERARNLLSDARDLMELGQHQGGVMHGTVRLGCIPTIAPFLLSKLLQECGKA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHH
YPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFHCKMVGQDPFHMVMPASMAAG
CCHHHHHHHCCCHHHHHHHHHCCCEEEEEEEEEHHHCCEEEEEECCCCCHHHHHHHHHHC
LHTPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLG
CCCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
TTFLPQMAIDSGILDNTDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKLAELLTPLIEP
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCCCEECCCCHHHHHHHHHHHHHHHHCCC
KT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA