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The map label for this gene is lspA [H]

Identifier: 145296100

GI number: 145296100

Start: 2224934

End: 2225515

Strand: Reverse

Name: lspA [H]

Synonym: cgR_2021

Alternate gene names: 145296100

Gene position: 2225515-2224934 (Counterclockwise)

Preceding gene: 145296103

Following gene: 145296099

Centisome position: 67.15

GC content: 51.03

Gene sequence:

>582_bases
ATGGTCAACGTGACCTCAAAGGATGCAGGGGCAAACATGACCCCCATGAGTAAGAAAGAAAAGAGGACAACCGTTAAACA
GGTGGTTGCCTTGATGGCCGCCATCGTTGTGGTGATTGCGTCCCTAGACCAAATAGTCAAGCAGATTATGCTTAGTTGGT
TGGAACCTGGCGTTCCCGTTCCCATCATTGGGGATTGGTTCCGCTTCTACCTCCTGTTTAACCCCGGAGCCGCATTTTCG
ATGGGTGGGGAAAACAGCACCTGGATCTTTACAACCATCCAGTTGAGCTTCGTCATCGGTATCGCAATCTATGCCCCACG
CATCAAACACAAGTGGATCGCGGCAGGACTTGCCCTTGTTGCCGGTGGAGCCTTGGGAAACGTGTTGGACCGGTTGTTCA
GAGATCCTTCCTTCTTCTTCGGACATGTTGTTGATTACATCTCCGTAGGAAACTTTGCAGTATTTAATATCGCCGATGCC
TCGATTTCTTGCGGCGTCGTGGTGTTCCTGATCGGAATGTTCCTTGAGGACCGTGAAAACGCCCAGCATGCCAAAGCAAC
TGACGAGAAGGATGAGGCCTGA

Upstream 100 bases:

>100_bases
GAATTTTTGCTGCAACTGTGTAAAAACCAGCGCTGAATTAAAGATCACCTTTCACCCTTAATTGAGCCTGGGTGGAAGTT
TCTACCGCTCATGGGGAAAG

Downstream 100 bases:

>100_bases
TGAACAACCGACAAAGCAGAACCCTTCCCGTACCAGAAGGACTGGCAGGCATGCGTGTGGACGCAGCACTGTCCAAGTTG
CTGGGAATTTCACGCACCGT

Product: hypothetical protein

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MVNVTSKDAGANMTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPIIGDWFRFYLLFNPGAAFS
MGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADA
SISCGVVVFLIGMFLEDRENAQHAKATDEKDEA

Sequences:

>Translated_193_residues
MVNVTSKDAGANMTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPIIGDWFRFYLLFNPGAAFS
MGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADA
SISCGVVVFLIGMFLEDRENAQHAKATDEKDEA
>Mature_193_residues
MVNVTSKDAGANMTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPVPIIGDWFRFYLLFNPGAAFS
MGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALVAGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADA
SISCGVVVFLIGMFLEDRENAQHAKATDEKDEA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 21029; Mature: 21029

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00855 SPASE_II ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVTSKDAGANMTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIIGDWFRFYLLFNPGAAFSMGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALV
CCHHHHHHHHHEECCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASISCGVVVFLIGMFLEDREN
HCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCC
AQHAKATDEKDEA
CHHHCCCCCCCCC
>Mature Secondary Structure
MVNVTSKDAGANMTPMSKKEKRTTVKQVVALMAAIVVVIASLDQIVKQIMLSWLEPGVPV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PIIGDWFRFYLLFNPGAAFSMGGENSTWIFTTIQLSFVIGIAIYAPRIKHKWIAAGLALV
CCHHHHHHHHHEECCCCEEECCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AGGALGNVLDRLFRDPSFFFGHVVDYISVGNFAVFNIADASISCGVVVFLIGMFLEDREN
HCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCC
AQHAKATDEKDEA
CHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]