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The map label for this gene is trpC [H]

Identifier: 145296053

GI number: 145296053

Start: 2174037

End: 2174822

Strand: Reverse

Name: trpC [H]

Synonym: cgR_1975

Alternate gene names: 145296053

Gene position: 2174822-2174037 (Counterclockwise)

Preceding gene: 145296054

Following gene: 145296052

Centisome position: 65.62

GC content: 50.51

Gene sequence:

>786_bases
ATGGTTGCAACAGAGAACCGCATGTTGATGGAAATCGCTGCGGAAATATCGACTCGGGAAGCAACGCTTGGTTTTCAAGA
AGTCAAAACTAAATCTCGATCAGCAGGTCTCACGGCGGCTTTCGATATCGCTTCAGTCTTTTTTTCGTCTGGATGTAATG
TCGTAGTCGCCTTTGATCGTTTTGCATCCAATTGGTCTGATCATTCGGATCATGTGGACTACGCTGCACAGGTTGCGGGT
TTTGGCGCATCAATGCTTGCATATACGGTGCGCAGGGGACAGTTTGATACCGCAGTACGCGATATCAGGGACATCAAATC
TGAAGTAGACATTCCCATTCTGCTTCATGATCCCATCATCGATCCGTATCAAATTCACGAAGCCCGCGTCATGGGCATCG
ACGCTCTTCAATTCCCCGTATGGGCGATGGAACAAGCTCGACTGGAATCTTTGGTGGACCGCACCGAATCATTGGGCATG
ACAGCCATCGTGTCTGTGCGAAACCACGAAGAAGCGCATCGTGCTGTGGACGCAGGAGCGACAGTGGTAGCAATTGATAT
TACTGGTTATACCGGCTCACTCACTTTGCCTGAAGCGTTTTCGGGTATCACCCAATTCATGCCCAAAGAGGTAGCCCGCA
TTGTGCTCGGAGGTTGCAGCAGCCCTAAAGAACTCATGCGGTTTGCACGACATTCTGCAGACGCCATCTTTGTTCCACAT
GCAGACCTGGCCACCACAAAATCTCTTGTGACAGCAGGTATGCATCCAGCGTGCCCATCGCGTTGA

Upstream 100 bases:

>100_bases
GAAACCCCAGGTCAAAGCTAGGGTGTGGCACCCTGATTTCTTTCGCCATGTGTGTTCGGGATAACCTTAAACACAGCATT
GGTTGGAAGGAGGTTGGGGC

Downstream 100 bases:

>100_bases
AGAGGTGCTCTGTGGTCAGCTGACCGGGGTAGCGGGCGGTGGGCGGACAAGTCTTGCTAGATTGAAGTGCATTACTTGTC
GCCTGACTGTTAGGTTTACG

Product: hypothetical protein

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MVATENRMLMEIAAEISTREATLGFQEVKTKSRSAGLTAAFDIASVFFSSGCNVVVAFDRFASNWSDHSDHVDYAAQVAG
FGASMLAYTVRRGQFDTAVRDIRDIKSEVDIPILLHDPIIDPYQIHEARVMGIDALQFPVWAMEQARLESLVDRTESLGM
TAIVSVRNHEEAHRAVDAGATVVAIDITGYTGSLTLPEAFSGITQFMPKEVARIVLGGCSSPKELMRFARHSADAIFVPH
ADLATTKSLVTAGMHPACPSR

Sequences:

>Translated_261_residues
MVATENRMLMEIAAEISTREATLGFQEVKTKSRSAGLTAAFDIASVFFSSGCNVVVAFDRFASNWSDHSDHVDYAAQVAG
FGASMLAYTVRRGQFDTAVRDIRDIKSEVDIPILLHDPIIDPYQIHEARVMGIDALQFPVWAMEQARLESLVDRTESLGM
TAIVSVRNHEEAHRAVDAGATVVAIDITGYTGSLTLPEAFSGITQFMPKEVARIVLGGCSSPKELMRFARHSADAIFVPH
ADLATTKSLVTAGMHPACPSR
>Mature_261_residues
MVATENRMLMEIAAEISTREATLGFQEVKTKSRSAGLTAAFDIASVFFSSGCNVVVAFDRFASNWSDHSDHVDYAAQVAG
FGASMLAYTVRRGQFDTAVRDIRDIKSEVDIPILLHDPIIDPYQIHEARVMGIDALQFPVWAMEQARLESLVDRTESLGM
TAIVSVRNHEEAHRAVDAGATVVAIDITGYTGSLTLPEAFSGITQFMPKEVARIVLGGCSSPKELMRFARHSADAIFVPH
ADLATTKSLVTAGMHPACPSR

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322638, Length=197, Percent_Identity=24.8730964467005, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 28360; Mature: 28360

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATENRMLMEIAAEISTREATLGFQEVKTKSRSAGLTAAFDIASVFFSSGCNVVVAFDR
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEHH
FASNWSDHSDHVDYAAQVAGFGASMLAYTVRRGQFDTAVRDIRDIKSEVDIPILLHDPII
HHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCC
DPYQIHEARVMGIDALQFPVWAMEQARLESLVDRTESLGMTAIVSVRNHEEAHRAVDAGA
CCHHHHHHHEECCHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCC
TVVAIDITGYTGSLTLPEAFSGITQFMPKEVARIVLGGCSSPKELMRFARHSADAIFVPH
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECC
ADLATTKSLVTAGMHPACPSR
CCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVATENRMLMEIAAEISTREATLGFQEVKTKSRSAGLTAAFDIASVFFSSGCNVVVAFDR
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEHH
FASNWSDHSDHVDYAAQVAGFGASMLAYTVRRGQFDTAVRDIRDIKSEVDIPILLHDPII
HHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCC
DPYQIHEARVMGIDALQFPVWAMEQARLESLVDRTESLGMTAIVSVRNHEEAHRAVDAGA
CCHHHHHHHEECCHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCC
TVVAIDITGYTGSLTLPEAFSGITQFMPKEVARIVLGGCSSPKELMRFARHSADAIFVPH
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEECC
ADLATTKSLVTAGMHPACPSR
CCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA