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The map label for this gene is dapB

Identifier: 145295877

GI number: 145295877

Start: 2000214

End: 2000960

Strand: Reverse

Name: dapB

Synonym: cgR_1802

Alternate gene names: 145295877

Gene position: 2000960-2000214 (Counterclockwise)

Preceding gene: 145295879

Following gene: 145295876

Centisome position: 60.38

GC content: 54.22

Gene sequence:

>747_bases
ATGGGAATCAAGGTTGGCGTTCTCGGAGCCAAAGGCCGTGTTGGTCAAACTATTGTGGCAGCAGTCAATGAGTCCGATGA
TCTGGAGCTTGTTGCAGAGATCGGCGTCGACGATGATTTGAGCCTTCTGGTAGACAACGGCGCTGAAGTTGTCGTTGACT
TCACCACTCCTAACGCTGTGATGGGCAACCTGGAGTTCTGCATCAACAACGGCATTTCTGCGGTTGTTGGAACCACGGGC
TTCGATGATGCTCGTTTGGAGCAGGTTCGCGCTTGGCTTGAAGGAAAAGACAATGTCGGTGTTCTGATCGCACCTAACTT
TGCTATCTCTGCGGTGTTGACCATGGTCTTTTCCAAGCAGGCTGCCCGCTTCTTCGAATCAGCTGAAGTTATTGAGCTGC
ACCACCCCAACAAGCTGGATGCACCTTCAGGCACCGCGATCCACACTGCTCAAGGCATTGCTGCGGCACGCAAAGAAGCA
GGCATGGACGCACAGCCAGATGCGACCGAGCAGGCACTTGAGGGTTCCCGTGGCGCAAGCGTAGATGGAATCCCAGTTCA
CGCAGTCCGCATGTCCGGCATGGTTGCTCACGAGCAAGTTATCTTTGGCACCCAGGGTCAGACCTTGACCATCAAGCAGG
ACTCCTATGATCGCAACTCATTTGCACCAGGTGTCTTGGTGGGTGTGCGCAACATTGCACAGCACCCAGGCCTAGTCGTA
GGACTTGAGCATTACCTAGGCCTGTAA

Upstream 100 bases:

>100_bases
AACGGTCAGTTAGGTATGGATATCAGCACCTTCTGAACGGGTACGTCTAGACTGGTGGGCGTTTGAAAAACTCTTCGCCC
CACGAAAATGAAGGAGCATA

Downstream 100 bases:

>100_bases
AGGCTCATTTCAGCAGCGGGTGGAATTTTTTAAAAGGAGCGTTTAAAGGCTGTGGCCGAACAAGTTAAATTGAGCGTGGA
GTTGATAGCGTGCAGTTCTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MGIKVGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDDDLSLLVDNGAEVVVDFTTPNAVMGNLEFCINNGISAVVGTTG
FDDARLEQVRAWLEGKDNVGVLIAPNFAISAVLTMVFSKQAARFFESAEVIELHHPNKLDAPSGTAIHTAQGIAAARKEA
GMDAQPDATEQALEGSRGASVDGIPVHAVRMSGMVAHEQVIFGTQGQTLTIKQDSYDRNSFAPGVLVGVRNIAQHPGLVV
GLEHYLGL

Sequences:

>Translated_248_residues
MGIKVGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDDDLSLLVDNGAEVVVDFTTPNAVMGNLEFCINNGISAVVGTTG
FDDARLEQVRAWLEGKDNVGVLIAPNFAISAVLTMVFSKQAARFFESAEVIELHHPNKLDAPSGTAIHTAQGIAAARKEA
GMDAQPDATEQALEGSRGASVDGIPVHAVRMSGMVAHEQVIFGTQGQTLTIKQDSYDRNSFAPGVLVGVRNIAQHPGLVV
GLEHYLGL
>Mature_247_residues
GIKVGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDDDLSLLVDNGAEVVVDFTTPNAVMGNLEFCINNGISAVVGTTGF
DDARLEQVRAWLEGKDNVGVLIAPNFAISAVLTMVFSKQAARFFESAEVIELHHPNKLDAPSGTAIHTAQGIAAARKEAG
MDAQPDATEQALEGSRGASVDGIPVHAVRMSGMVAHEQVIFGTQGQTLTIKQDSYDRNSFAPGVLVGVRNIAQHPGLVVG
LEHYLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=251, Percent_Identity=29.0836653386454, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CORGB (A4QEY0)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138698.1
- ProteinModelPortal:   A4QEY0
- SMR:   A4QEY0
- STRING:   A4QEY0
- GeneID:   4993262
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1802
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 25981; Mature: 25850

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKVGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDDDLSLLVDNGAEVVVDFTTPNAV
CCEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCEEEEEECCCCCC
MGNLEFCINNGISAVVGTTGFDDARLEQVRAWLEGKDNVGVLIAPNFAISAVLTMVFSKQ
CCCHHEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
AARFFESAEVIELHHPNKLDAPSGTAIHTAQGIAAARKEAGMDAQPDATEQALEGSRGAS
HHHHHCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCC
VDGIPVHAVRMSGMVAHEQVIFGTQGQTLTIKQDSYDRNSFAPGVLVGVRNIAQHPGLVV
CCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEE
GLEHYLGL
EHHHHHCC
>Mature Secondary Structure 
GIKVGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDDDLSLLVDNGAEVVVDFTTPNAV
CEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCEEEEEECCCCCC
MGNLEFCINNGISAVVGTTGFDDARLEQVRAWLEGKDNVGVLIAPNFAISAVLTMVFSKQ
CCCHHEEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
AARFFESAEVIELHHPNKLDAPSGTAIHTAQGIAAARKEAGMDAQPDATEQALEGSRGAS
HHHHHCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCC
VDGIPVHAVRMSGMVAHEQVIFGTQGQTLTIKQDSYDRNSFAPGVLVGVRNIAQHPGLVV
CCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEE
GLEHYLGL
EHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA