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The map label for this gene is ygcA [C]

Identifier: 145295807

GI number: 145295807

Start: 1924563

End: 1925801

Strand: Reverse

Name: ygcA [C]

Synonym: cgR_1732

Alternate gene names: 145295807

Gene position: 1925801-1924563 (Counterclockwise)

Preceding gene: 145295808

Following gene: 145295806

Centisome position: 58.11

GC content: 57.14

Gene sequence:

>1239_bases
ATGACTGACACCGTCGAACTCGCCAAAGGCGACATCATCTCCGTTGAGGTGCTAAGGCCGGCTCACGGCGGCGAAGGCAT
CGGACACCACGATGGCCGCGTCATCTTCGTGAAAGGTGGCATTCCCGGCGATGTCGTGGATGTAGAAATCGCACAGTTGA
AGAAGAAGTGGGCACGCGGTGAAGTGGTTAAGGTAACCACCGCGTCTGCTGATCGTGTCGATTCCCGTTGCCCAGCAGCG
GCAGCAGGTGCTGGTTGCTGTGACTATGCAGAACTCAACCCAACTGTGGAACTTGAGATCAAGTCCCGCGTGCTTCGTGA
TCAGTTGGAACGCATCGGTGGAATCGATGAGCTTCCTGAATTTGAGCTTCATGATCTGGAGCCGACAGCTGGTTGGCGTA
CCCGTGTCCGCCTCGGCGTTGATGCGTCTGGTCGCGCCGGGTTCCGCAAGCTGAAGTCCAATGAGTTGGTTACTGAGGTT
GCGTGTTCTCAGGTTGTGCCAGAGCTTCTTGAGGGCCTTGTGGGTGAGGGCGCTCGTCGTTTCACCCCTGGCGTGGAGAT
CATTGCAGCTATTGATGATGCGGGTCAGCGCCACGTTGTGGAATCCCGTAAGGCTCCTCGTGGTCGTCGTACTGAAACTG
TGTTGAAGGTGCTGGAAGGCACTGGCGAGGTGGAGCAGAAGGTAGGCGATTACACCTGGAAGTTCCCAGTTTCTTCCTTC
TGGCAGGCGCACACCAAGGCCCCTGCGGCGTATTCAGAGTTCATCGCCGAAGCGTTAACCGGATTGGAACTGGTTGACGT
CGATAAGCGTGGCCCTGTTGCGTGGGACCTTTATGGCGGCGTCGGCCTGTTCGCGCCGATTATCACCAGCAAGCTGCAGG
CAGCTGTCCACTCTGTGGAGCTGTCCCCAGGGTCAGCGGAGGCTGGCGAAGAGGCGTTGGCTGGTTTGCCTGTCACTTTC
CACACTGGTCGGGTAGAGGGCATGGCGTCCCAGCTGCCTTCGCCAAACGTGGTTGTTTTGGATCCTCCTCGCACCGGTGC
AGGCAGTGACGTGTTGAAGAGCATCGCGGAGGCTAAGCCTCAGCTGGTTATCCACATTGGTTGTGACCCAGCGACTTTCG
CTCGCGACGTTGCCGATTGGAAGCTCAACGGCTACGAAATGGATCAATTGGCTGTTTTTAACGCGTTCCCTGGAACTCAC
CACTTTGAGACGATTGGTGTATTTGTCCGCGTTTCCTAA

Upstream 100 bases:

>100_bases
GGAAATACCCCCAACGCAGAGTAGGGTTAAACTCTTTGCGCTGTCCCGCTCCAAGCAACGGGACAGAAACTTTTTCAAGT
GAAACGAGGACTACACTCAC

Downstream 100 bases:

>100_bases
GGCGGATTAAGCCTTGGCTATCGAGACAGAGTAATATAGCTCCAACACCGTAGGTGCACATTTGTTTTGTCACCTGCACA
AAAGTGTCGCCAGCCCGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARGEVVKVTTASADRVDSRCPAA
AAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPEFELHDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEV
ACSQVVPELLEGLVGEGARRFTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVELSPGSAEAGEEALAGLPVTF
HTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKPQLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTH
HFETIGVFVRVS

Sequences:

>Translated_412_residues
MTDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARGEVVKVTTASADRVDSRCPAA
AAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPEFELHDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEV
ACSQVVPELLEGLVGEGARRFTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVELSPGSAEAGEEALAGLPVTF
HTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKPQLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTH
HFETIGVFVRVS
>Mature_411_residues
TDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARGEVVKVTTASADRVDSRCPAAA
AGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPEFELHDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEVA
CSQVVPELLEGLVGEGARRFTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSFW
QAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVELSPGSAEAGEEALAGLPVTFH
TGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKPQLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTHH
FETIGVFVRVS

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=442, Percent_Identity=27.3755656108597, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787083, Length=208, Percent_Identity=23.5576923076923, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 44130; Mature: 43998

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARG
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCC
EVVKVTTASADRVDSRCPAAAAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPE
CEEEEEECCCHHHHCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCC
FELHDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEVACSQVVPELLEGLVGEGARR
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
FTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
CCCCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCEEEECCHHHH
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVE
HHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEE
LSPGSAEAGEEALAGLPVTFHTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKP
CCCCCCCCCHHHHHCCCEEEECCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCC
QLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTHHFETIGVFVRVS
EEEEEECCCHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
TDTVELAKGDIISVEVLRPAHGGEGIGHHDGRVIFVKGGIPGDVVDVEIAQLKKKWARG
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCC
EVVKVTTASADRVDSRCPAAAAGAGCCDYAELNPTVELEIKSRVLRDQLERIGGIDELPE
CEEEEEECCCHHHHCCCCCHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCC
FELHDLEPTAGWRTRVRLGVDASGRAGFRKLKSNELVTEVACSQVVPELLEGLVGEGARR
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
FTPGVEIIAAIDDAGQRHVVESRKAPRGRRTETVLKVLEGTGEVEQKVGDYTWKFPVSSF
CCCCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCEEEECCHHHH
WQAHTKAPAAYSEFIAEALTGLELVDVDKRGPVAWDLYGGVGLFAPIITSKLQAAVHSVE
HHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEE
LSPGSAEAGEEALAGLPVTFHTGRVEGMASQLPSPNVVVLDPPRTGAGSDVLKSIAEAKP
CCCCCCCCCHHHHHCCCEEEECCCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCC
QLVIHIGCDPATFARDVADWKLNGYEMDQLAVFNAFPGTHHFETIGVFVRVS
EEEEEECCCHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]