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The map label for this gene is pyc [H]

Identifier: 145294862

GI number: 145294862

Start: 893777

End: 897199

Strand: Direct

Name: pyc [H]

Synonym: cgR_0809

Alternate gene names: 145294862

Gene position: 893777-897199 (Clockwise)

Preceding gene: 145294861

Following gene: 145294863

Centisome position: 26.97

GC content: 56.59

Gene sequence:

>3423_bases
GTGTCGACTCACACATCTTCAACGCTTCCAGCATTCAAAAAGATCTTGGTAGCAAACCGCGGCGAAATCGCGGTCCGTGC
TTTCCGTGCAGCACTCGAAACCGGTGCAGCCACGGTAGCTATTTACCCCCGTGAAGATCGGGGATCATTCCACCGCTCTT
TTGCTTCTGAAGCTGTCCGCATTGGTACTGAAGGCTCACCAGTCAAGGCGTACCTGGACATCGATGAAATTATCGGTGCA
GCTAAAAAAGTTAAAGCAGATGCTATTTACCCGGGATATGGCTTCCTGTCTGAAAATGCCCAGCTTGCCCGCGAGTGCGC
GGAAAACGGCATTACTTTTATTGGCCCAACCCCAGAGGTTCTTGATCTCACCGGTGATAAGTCTCGTGCGGTAACCGCCG
CGAAGAAGGCTGGTCTGCCAGTTTTGGCGGAATCCACCCCGAGCAAAAACATCGATGACATCGTTAAAAGCGCTGAAGGC
CAGACTTACCCCATCTTTGTAAAGGCAGTTGCCGGTGGTGGCGGACGCGGTATGCGCTTTGTTTCTTCACCTGATGAGCT
TCGCAAATTGGCAACAGAAGCATCTCGTGAAGCTGAAGCGGCATTCGGCGACGGTTCGGTATATGTCGAGCGTGCTGTGA
TTAACCCCCAGCACATTGAAGTGCAGATCCTTGGCGATCGCACTGGAGAAGTTGTACACCTTTATGAACGTGACTGCTCA
CTGCAGCGTCGTCACCAAAAAGTTGTCGAAATTGCGCCAGCACAGCATTTGGATCCAGAACTGCGTGATCGCATTTGTGC
GGATGCAGTAAAGTTCTGCCGCTCCATTGGTTACCAGGGCGCGGGAACTGTGGAATTCTTGGTCGATGAAAAGGGCAACC
ACGTTTTCATCGAAATGAACCCACGTATCCAGGTTGAGCACACCGTGACTGAAGAAGTCACCGAGGTGGACCTGGTGAAG
GCGCAGATGCGCTTGGCTGCTGGTGCAACCTTGAAGGAATTGGGTCTGACCCAAGATAAGATCAAGACCCACGGTGCGGC
ACTGCAGTGCCGCATCACCACGGAAGATCCAAACAACGGCTTCCGCCCAGATACCGGAACTATCACCGCGTACCGCTCAC
CAGGCGGAGCTGGCGTTCGTCTTGACGGTGCAGCTCAGCTCGGTGGCGAAATCACCGCACACTTTGACTCCATGCTGGTG
AAAATGACCTGCCGTGGTTCCGATTTTGAAACTGCTGTTGCTCGTGCACAGCGCGCGTTGGCTGAGTTCACCGTGTCTGG
TGTTGCAACCAACATTGGTTTCTTGCGTGCGTTGCTGCGTGAAGAGGACTTTACTTCCAAGCGCATCGCCACCGGATTTA
TCGGCGATCACCCACACCTCCTTCAGGCTCCACCTGCGGATGATGAGCAGGGACGCATCCTGGATTACTTGGCAGATGTC
ACCGTGAACAAGCCTCATGGTGTGCGTCCAAAGGATGTTGCAGCACCAATCGATAAGCTGCCCAACATCAAGGATCTGCC
ACTGCCACGCGGTTCCCGTGACCGCCTGAAGCAGCTTGGACCAGCAGCGTTTGCCCGCGATCTCCGTGAGCAGGACGCAC
TGGCAGTTACTGATACCACCTTCCGCGATGCACACCAGTCTTTGCTTGCGACCCGAGTCCGCTCATTCGCACTGAAGCCT
GCGGCAGAGGCCGTCGCAAAGCTGACTCCTGAGCTTTTGTCCGTGGAGGCCTGGGGCGGTGCGACCTACGATGTGGCGAT
GCGTTTCCTCTTTGAGGATCCGTGGGACAGGCTCGACGAGCTGCGCGAGGCGATGCCGAATGTGAACATTCAGATGCTGC
TTCGCGGCCGCAACACCGTGGGATACACCCCATACCCAGACTCCGTCTGTCGCGCGTTTGTTAAGGAAGCTGCCACCTCC
GGCGTGGACATCTTCCGCATCTTCGACGCGCTTAACGACGTCTCCCAGATGCGTCCAGCAATCGACGCAGTCCTGGAGAC
CAACACCGCGGTCGCTGAAGTGGCTATGGCTTATTCTGGTGATCTTTCCGATCCGAATGAAAAGCTCTACACCCTGGATT
ACTACCTGAAGATGGCAGAGGAGATCGTCAAGTCTGGCGCTCACATTCTGGCTATTAAGGATATGGCTGGTCTGCTTCGC
CCAGCTGCAGCCACCAAGCTGGTCACCGCACTGCGCCGTGAATTTGATCTGCCAGTGCACGTGCACACCCACGACACTGC
GGGTGGCCAGCTGGCAACCTACTTTGCTGCAGCTCAAGCTGGTGCAGATGCTGTTGACGGTGCTTCCGCACCACTGTCTG
GCACCACCTCCCAGCCATCCCTGTCTGCCATTGTTGCTGCATTCGCGCACACCCGTCGCGATACCGGTTTGAGCCTCGAG
GCTGTTTCTGACCTCGAGCCATACTGGGAAGCAGTGCGCGGACTGTACCTGCCATTTGAGTCTGGAACCCCAGGCCCAAC
CGGTCGCGTCTACCGCCACGAAATCCCAGGCGGACAGCTGTCCAACCTGCGTGCACAGGCCACCGCACTGGGCCTTGCGG
ATCGTTTCGAACTCATCGAAGACAACTACGCGGCAGTTAATGAGATGCTGGGACGCCCAACCAAGGTCACCCCATCCTCC
AAGGTTGTTGGCGACCTCGCACTCCACCTCGTTGGTGCGGGTGTGGATCCAGCAGACTTTGCTGCAGATCCACAAAAGTA
CGACATCCCAGACTCTGTCATCGCGTTCCTGCGCGGCGAGCTTGGTAACCCTCCAGGTGGCTGGCCAGAGCCACTGCGCA
CCCGCGCACTGGAAGGCCGCTCCGAAGGCAAGGCACCTCTGACGGAAGTTCCTGAGGAAGAGCAGGCGCACCTCGACGCT
GATGATTCCAAGGAACGTCGCAACAGCCTCAACCGCCTGCTGTTCCCGAAGCCAACCGAAGAGTTCCTCGAGCACCGTCG
CCGCTTCGGCAACACCTCTGCGCTGGATGATCGTGAATTCTTCTACGGCCTGGTCGAAGGCCGCGAGACTTTGATCCGCC
TGCCAGATGTGCGCACCCCACTGCTTGTTCGCCTGGATGCGATCTCCGAGCCAGACGATAAGGGTATGCGCAATGTTGTG
GCCAACGTCAACGGCCAGATCCGCCCAATGCGTGTGCGTGACCGCTCCGTTGAGTCTGTCACCGCAACCGCAGAAAAGGC
AGATTCCTCCAACAAGGGCCATGTTGCTGCACCATTCGCTGGTGTTGTCACTGTGACTGTTGCTGAAGGTGATGAGGTCA
AGGCTGGAGATGCAGTCGCAATCATCGAGGCTATGAAGATGGAAGCAACAATCACTGCTTCTGTTGACGGCAAAATCGAT
CGCGTTGTGGTTCCTGCTGCAACGAAGGTGGAAGGTGGCGACTTGATCGTCGTCATTTCCTAA

Upstream 100 bases:

>100_bases
AAAACCGATGTTTGATTGGGGGAATCGGGGGTTACGATACTAGGACGAAGTGACTGCTATCACCCTTGGTGGTCTCTTGT
TGAAAGGAACAATTACTCTA

Downstream 100 bases:

>100_bases
ACCTTTCTGTAAAAAGCCCCGCTTCTTCCTCATGGAGGAGGCGGGGCTTTTTGGGCCAATATGGGAGATGGGGGAGTTGG
ATTTGGTCTGATTCGACACT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1140; Mature: 1139

Protein sequence:

>1140_residues
MSTHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVRIGTEGSPVKAYLDIDEIIGA
AKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEVLDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDDIVKSAEG
QTYPIFVKAVAGGGGRGMRFVSSPDELRKLATEASREAEAAFGDGSVYVERAVINPQHIEVQILGDRTGEVVHLYERDCS
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMNPRIQVEHTVTEEVTEVDLVK
AQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNGFRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLV
KMTCRGSDFETAVARAQRALAEFTVSGVATNIGFLRALLREEDFTSKRIATGFIGDHPHLLQAPPADDEQGRILDYLADV
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTTFRDAHQSLLATRVRSFALKP
AAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDELREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAATS
GVDIFRIFDALNDVSQMRPAIDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
PAAATKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPSLSAIVAAFAHTRRDTGLSLE
AVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQLSNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSS
KVVGDLALHLVGAGVDPADFAADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTPLLVRLDAISEPDDKGMRNVV
ANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFAGVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKID
RVVVPAATKVEGGDLIVVIS

Sequences:

>Translated_1140_residues
MSTHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVRIGTEGSPVKAYLDIDEIIGA
AKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEVLDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDDIVKSAEG
QTYPIFVKAVAGGGGRGMRFVSSPDELRKLATEASREAEAAFGDGSVYVERAVINPQHIEVQILGDRTGEVVHLYERDCS
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMNPRIQVEHTVTEEVTEVDLVK
AQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNGFRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLV
KMTCRGSDFETAVARAQRALAEFTVSGVATNIGFLRALLREEDFTSKRIATGFIGDHPHLLQAPPADDEQGRILDYLADV
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTTFRDAHQSLLATRVRSFALKP
AAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDELREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAATS
GVDIFRIFDALNDVSQMRPAIDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
PAAATKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPSLSAIVAAFAHTRRDTGLSLE
AVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQLSNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSS
KVVGDLALHLVGAGVDPADFAADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTPLLVRLDAISEPDDKGMRNVV
ANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFAGVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKID
RVVVPAATKVEGGDLIVVIS
>Mature_1139_residues
STHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVRIGTEGSPVKAYLDIDEIIGAA
KKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEVLDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDDIVKSAEGQ
TYPIFVKAVAGGGGRGMRFVSSPDELRKLATEASREAEAAFGDGSVYVERAVINPQHIEVQILGDRTGEVVHLYERDCSL
QRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMNPRIQVEHTVTEEVTEVDLVKA
QMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNGFRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLVK
MTCRGSDFETAVARAQRALAEFTVSGVATNIGFLRALLREEDFTSKRIATGFIGDHPHLLQAPPADDEQGRILDYLADVT
VNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTTFRDAHQSLLATRVRSFALKPA
AEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDELREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAATSG
VDIFRIFDALNDVSQMRPAIDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLRP
AAATKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPSLSAIVAAFAHTRRDTGLSLEA
VSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQLSNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSSK
VVGDLALHLVGAGVDPADFAADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDAD
DSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTPLLVRLDAISEPDDKGMRNVVA
NVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFAGVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKIDR
VVVPAATKVEGGDLIVVIS

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1142, Percent_Identity=46.584938704028, Blast_Score=967, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1142, Percent_Identity=46.584938704028, Blast_Score=967, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1142, Percent_Identity=46.584938704028, Blast_Score=967, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=456, Percent_Identity=40.7894736842105, Blast_Score=355, Evalue=2e-97,
Organism=Homo sapiens, GI189095269, Length=458, Percent_Identity=42.5764192139738, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI65506442, Length=454, Percent_Identity=42.511013215859, Blast_Score=328, Evalue=2e-89,
Organism=Homo sapiens, GI295821183, Length=454, Percent_Identity=42.511013215859, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI38679971, Length=507, Percent_Identity=29.7830374753452, Blast_Score=227, Evalue=6e-59,
Organism=Homo sapiens, GI38679960, Length=507, Percent_Identity=29.7830374753452, Blast_Score=227, Evalue=6e-59,
Organism=Homo sapiens, GI38679977, Length=507, Percent_Identity=29.7830374753452, Blast_Score=227, Evalue=6e-59,
Organism=Homo sapiens, GI38679967, Length=507, Percent_Identity=29.7830374753452, Blast_Score=227, Evalue=6e-59,
Organism=Homo sapiens, GI38679974, Length=507, Percent_Identity=29.7830374753452, Blast_Score=226, Evalue=8e-59,
Organism=Homo sapiens, GI134142062, Length=508, Percent_Identity=28.3464566929134, Blast_Score=210, Evalue=6e-54,
Organism=Escherichia coli, GI1789654, Length=434, Percent_Identity=46.7741935483871, Blast_Score=344, Evalue=1e-95,
Organism=Escherichia coli, GI1786216, Length=271, Percent_Identity=23.9852398523985, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1148, Percent_Identity=45.1219512195122, Blast_Score=948, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=466, Percent_Identity=40.7725321888412, Blast_Score=320, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17567343, Length=450, Percent_Identity=39.5555555555556, Blast_Score=314, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI133931226, Length=486, Percent_Identity=29.6296296296296, Blast_Score=216, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI71997168, Length=503, Percent_Identity=27.2365805168986, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71997163, Length=504, Percent_Identity=27.1825396825397, Blast_Score=197, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1166, Percent_Identity=45.5403087478559, Blast_Score=934, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1160, Percent_Identity=46.4655172413793, Blast_Score=930, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=37.1111111111111, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6323863, Length=454, Percent_Identity=31.057268722467, Blast_Score=206, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=28.7109375, Blast_Score=200, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6322569, Length=235, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24652212, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1155, Percent_Identity=44.2424242424242, Blast_Score=936, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=932, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=932, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=932, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=932, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1165, Percent_Identity=44.0343347639485, Blast_Score=932, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=467, Percent_Identity=39.186295503212, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24651759, Length=418, Percent_Identity=38.9952153110048, Blast_Score=296, Evalue=7e-80,
Organism=Drosophila melanogaster, GI161076407, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24586460, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24586458, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=4e-50,
Organism=Drosophila melanogaster, GI161076409, Length=503, Percent_Identity=27.8330019880716, Blast_Score=197, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 123128; Mature: 122996

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVR
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHE
IGTEGSPVKAYLDIDEIIGAAKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEV
ECCCCCCEEEEEEHHHHHCHHHHHCCCEECCCCCCCCCCHHHHHHHHHCCCEEECCCCCE
LDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDDIVKSAEGQTYPIFVKAVAGGGGRGMRF
EECCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCCCEE
VSSPDELRKLATEASREAEAAFGDGSVYVERAVINPQHIEVQILGDRTGEVVHLYERDCS
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCEEEEEHHCCH
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
PRIQVEHTVTEEVTEVDLVKAQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNG
CCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHCCCEEEEEEEECCCCCC
FRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLVKMTCRGSDFETAVARAQRAL
CCCCCCCEEEEECCCCCCEEECCHHHCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHH
AEFTVSGVATNIGFLRALLREEDFTSKRIATGFIGDHPHLLQAPPADDEQGRILDYLADV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCEECCCCCCCCCCHHHHHHHHC
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTT
EECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCEEEECCH
FRDAHQSLLATRVRSFALKPAAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHCCHHHHHHH
LREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAATSGVDIFRIFDALNDVSQMRPA
HHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
HHHHHHCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHH
PAAATKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPS
HHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
LSAIVAAFAHTRRDTGLSLEAVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQL
HHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHCEEEEECCCCCCCCCCEEEEECCCCCH
SNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSSKVVGDLALHLVGAGVDPADF
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTP
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEECCCCCCC
LLVRLDAISEPDDKGMRNVVANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFA
CEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCC
GVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKIDRVVVPAATKVEGGDLIVVIS
CEEEEEEECCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCCEECCCCEEEEEC
>Mature Secondary Structure 
STHTSSTLPAFKKILVANRGEIAVRAFRAALETGAATVAIYPREDRGSFHRSFASEAVR
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHE
IGTEGSPVKAYLDIDEIIGAAKKVKADAIYPGYGFLSENAQLARECAENGITFIGPTPEV
ECCCCCCEEEEEEHHHHHCHHHHHCCCEECCCCCCCCCCHHHHHHHHHCCCEEECCCCCE
LDLTGDKSRAVTAAKKAGLPVLAESTPSKNIDDIVKSAEGQTYPIFVKAVAGGGGRGMRF
EECCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCEEEEEEEEEECCCCCCCEE
VSSPDELRKLATEASREAEAAFGDGSVYVERAVINPQHIEVQILGDRTGEVVHLYERDCS
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCEEEEEHHCCH
LQRRHQKVVEIAPAQHLDPELRDRICADAVKFCRSIGYQGAGTVEFLVDEKGNHVFIEMN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEC
PRIQVEHTVTEEVTEVDLVKAQMRLAAGATLKELGLTQDKIKTHGAALQCRITTEDPNNG
CCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHCCCEEEEEEEECCCCCC
FRPDTGTITAYRSPGGAGVRLDGAAQLGGEITAHFDSMLVKMTCRGSDFETAVARAQRAL
CCCCCCCEEEEECCCCCCEEECCHHHCCCCHHHHHHHEEEEEEECCCCHHHHHHHHHHHH
AEFTVSGVATNIGFLRALLREEDFTSKRIATGFIGDHPHLLQAPPADDEQGRILDYLADV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCEECCCCCCCCCCHHHHHHHHC
TVNKPHGVRPKDVAAPIDKLPNIKDLPLPRGSRDRLKQLGPAAFARDLREQDALAVTDTT
EECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCEEEECCH
FRDAHQSLLATRVRSFALKPAAEAVAKLTPELLSVEAWGGATYDVAMRFLFEDPWDRLDE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHCCHHHHHHH
LREAMPNVNIQMLLRGRNTVGYTPYPDSVCRAFVKEAATSGVDIFRIFDALNDVSQMRPA
HHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IDAVLETNTAVAEVAMAYSGDLSDPNEKLYTLDYYLKMAEEIVKSGAHILAIKDMAGLLR
HHHHHHCCHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHH
PAAATKLVTALRREFDLPVHVHTHDTAGGQLATYFAAAQAGADAVDGASAPLSGTTSQPS
HHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
LSAIVAAFAHTRRDTGLSLEAVSDLEPYWEAVRGLYLPFESGTPGPTGRVYRHEIPGGQL
HHHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHCEEEEECCCCCCCCCCEEEEECCCCCH
SNLRAQATALGLADRFELIEDNYAAVNEMLGRPTKVTPSSKVVGDLALHLVGAGVDPADF
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AADPQKYDIPDSVIAFLRGELGNPPGGWPEPLRTRALEGRSEGKAPLTEVPEEEQAHLDA
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCC
DDSKERRNSLNRLLFPKPTEEFLEHRRRFGNTSALDDREFFYGLVEGRETLIRLPDVRTP
CCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHEEECCCCCCC
LLVRLDAISEPDDKGMRNVVANVNGQIRPMRVRDRSVESVTATAEKADSSNKGHVAAPFA
CEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCC
GVVTVTVAEGDEVKAGDAVAIIEAMKMEATITASVDGKIDRVVVPAATKVEGGDLIVVIS
CEEEEEEECCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCEEEECCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]