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The map label for this gene is nreC [H]

Identifier: 145294782

GI number: 145294782

Start: 790861

End: 791553

Strand: Direct

Name: nreC [H]

Synonym: cgR_0730

Alternate gene names: 145294782

Gene position: 790861-791553 (Clockwise)

Preceding gene: 145294779

Following gene: 145294783

Centisome position: 23.86

GC content: 58.59

Gene sequence:

>693_bases
ATGGTTGATGTGTTTTTGGTCGATGACCACTCCGTGTTTCGCTCCGGCGTCAAAGCAGAACTAGGCAACGCCGTCACAGT
AGTCGGCGAAGCAGGGACGGTGGCCGACGCCGTAGCCGGCATCAAGGCAAGCAAACCAGAGGTCGTGCTTCTCGACGTCC
ACATGCCCGATGGCGGCGGCCTCGCAGTGCTCCAGCAGATCAACGACTCCGATGTGGACACCATCTTCTTGGCACTCAGT
GTCTCTGACGCAGCTGAAGATGTCATCGCTATCATCCGTGGCGGTGCCAGGGGATACGTGACCAAATCGATCTCCGGTGA
AGAACTCGTCGAAGCCATCAACCGCGTGAAATCCGGCGACGCATTCTTCTCACCACGCCTGGCAGGCTTCGTCCTCGACG
CCTTCGCTGCCCCCGACTCCGCAGCTGGCGCCGGTATTGTCGACGCTCCCGAAAAAGACGCCGCCGTAGAATCCGGAAAA
ATCCTCGACGACCCAGTTGTCGACGCCCTCACCCGCCGCGAACTCGAAGTCCTCCGCCTACTAGCCCGCGGCTACACCTA
CAAAGAAATCGGCAAAGAACTGTTCATTTCCGTCAAAACCGTGGAAACCCACGCCTCAAACATTCTGCGAAAAACCCAGC
AATCCAACCGCCACGCACTGACCCGTTGGGCTCACTCGAGGGATCTTGACTGA

Upstream 100 bases:

>100_bases
ACGCATCAAATCTGAAATCGGCGAAGGCACCGAAGTGGCAATCACCATGGATGTGTAGTTGGTCGTACGCGCGTGTCTTC
GGGGCTGTAACCTGAAAGGC

Downstream 100 bases:

>100_bases
TGGCGGCTAAAAAGAGTGGCGCTGGTTCTCGGGGTGGGGCTGGGAGGTCAGCTTCGGCTGATAAACAGATCGATCAAAGC
CAAGCGAAATTCACCTTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MVDVFLVDDHSVFRSGVKAELGNAVTVVGEAGTVADAVAGIKASKPEVVLLDVHMPDGGGLAVLQQINDSDVDTIFLALS
VSDAAEDVIAIIRGGARGYVTKSISGEELVEAINRVKSGDAFFSPRLAGFVLDAFAAPDSAAGAGIVDAPEKDAAVESGK
ILDDPVVDALTRRELEVLRLLARGYTYKEIGKELFISVKTVETHASNILRKTQQSNRHALTRWAHSRDLD

Sequences:

>Translated_230_residues
MVDVFLVDDHSVFRSGVKAELGNAVTVVGEAGTVADAVAGIKASKPEVVLLDVHMPDGGGLAVLQQINDSDVDTIFLALS
VSDAAEDVIAIIRGGARGYVTKSISGEELVEAINRVKSGDAFFSPRLAGFVLDAFAAPDSAAGAGIVDAPEKDAAVESGK
ILDDPVVDALTRRELEVLRLLARGYTYKEIGKELFISVKTVETHASNILRKTQQSNRHALTRWAHSRDLD
>Mature_230_residues
MVDVFLVDDHSVFRSGVKAELGNAVTVVGEAGTVADAVAGIKASKPEVVLLDVHMPDGGGLAVLQQINDSDVDTIFLALS
VSDAAEDVIAIIRGGARGYVTKSISGEELVEAINRVKSGDAFFSPRLAGFVLDAFAAPDSAAGAGIVDAPEKDAAVESGK
ILDDPVVDALTRRELEVLRLLARGYTYKEIGKELFISVKTVETHASNILRKTQQSNRHALTRWAHSRDLD

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=224, Percent_Identity=33.0357142857143, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788521, Length=222, Percent_Identity=35.1351351351351, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=30.0469483568075, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787473, Length=225, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788712, Length=225, Percent_Identity=22.6666666666667, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786747, Length=214, Percent_Identity=23.8317757009346, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24394; Mature: 24394

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVFLVDDHSVFRSGVKAELGNAVTVVGEAGTVADAVAGIKASKPEVVLLDVHMPDGGG
CEEEEEECCHHHHHHCHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCCC
LAVLQQINDSDVDTIFLALSVSDAAEDVIAIIRGGARGYVTKSISGEELVEAINRVKSGD
EEEEECCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCC
AFFSPRLAGFVLDAFAAPDSAAGAGIVDAPEKDAAVESGKILDDPVVDALTRRELEVLRL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LARGYTYKEIGKELFISVKTVETHASNILRKTQQSNRHALTRWAHSRDLD
HHCCCCHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVDVFLVDDHSVFRSGVKAELGNAVTVVGEAGTVADAVAGIKASKPEVVLLDVHMPDGGG
CEEEEEECCHHHHHHCHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCCC
LAVLQQINDSDVDTIFLALSVSDAAEDVIAIIRGGARGYVTKSISGEELVEAINRVKSGD
EEEEECCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCC
AFFSPRLAGFVLDAFAAPDSAAGAGIVDAPEKDAAVESGKILDDPVVDALTRRELEVLRL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LARGYTYKEIGKELFISVKTVETHASNILRKTQQSNRHALTRWAHSRDLD
HHCCCCHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]