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The map label for this gene is aldH [H]

Identifier: 145294574

GI number: 145294574

Start: 584437

End: 585999

Strand: Reverse

Name: aldH [H]

Synonym: cgR_0525

Alternate gene names: 145294574

Gene position: 585999-584437 (Counterclockwise)

Preceding gene: 145294575

Following gene: 145294573

Centisome position: 17.68

GC content: 55.6

Gene sequence:

>1563_bases
ATGATTACCGCAACCGCACTGCATGGGTGTTCACTGATTGATGGCGAGTGGGTCGCTGGAAAAAATGGTGAGATTACAGG
ATTCGATCCGCGCACCAATGCGAGCCTGAACCCTTCCTACTCTTTAGCAAACCGCGCACAGCTGCGCGCCGCCACAACAT
CGGCGAAGCGAGCGTTTGAAAGCTACCGCCTCACTACTCCAGAGGTCAGAGCAGATTTCCTGGATTCCATCGCGGACAAC
ATCGATGACTTAACCGAAGAGATCGTGCAACGGGCGAGCCTGGAGACAGGTTTGGGAACCACCCGACTCACAGGCGAAGT
AGCCCGCACCAGCAACCAGCTCCGCCTGTTTGCAGAAACCGTGAGAAGCGGACAGTTCCACCGAGTACGCATTGAACGAG
GACCGCGGATTGATCTTCGCCAGCGTCAGGTTCCGTTGGGACCAGTCGCGGTATTCGGGGCAAGCAACTTCCCCCTCGCT
TTCTCTACTGCAGGTGGCGATACAGCATCAGCGTTGGCTGCAGGCTGCCCTGTGGTTTTTAAGGCGCATAATGCGCACCC
TGGAACCGCTGAGCTCGTCGGGCAAGCGGTGCGGGGAGCCGTCGAAAAGCATGAGTTTGATGCTGGTGTGTTTAACCTTG
TCTACGGCCGTGGCGTGGAAATTGGCCAGGAGCTGGCTGCGGATCCGAATATCACGGCAATCGGTTTTACCGGTTCACGC
CAGGGTGGTTTGGCACTGTCACAGACTGCGTTTAGCCGCCCAGTTCCCGTTCCAGTCTTTGCAGAAATGAGTGCCACCAA
CCCTGTGTTCGTCTTCCCCGGCGCGCTGGCGGATTTGGATGCATCGAGTTCCTTGGCTGAGGCGTTTACCGCTTCTGTCA
CAGGCAGCTCTGGGCAATTGTGTACAAAACCCGGTCTAGTTTTTATCCCGCGCGGTGTTGCTGGCGATGCTTTTGTAGAG
CTTGTGGCTGCCAAATTTAAAGAAACCACGGGTCAAACGATGCTCACGCAAGGCATTGCCCAGGCGTGGCAGCGCGGAGT
GGACAACCTTGCAGCACAACCAAGCGTAAAAATCCTCGCCCAAGGCACCCCCGGAGATGGAGAGAACGCGCCGGGCCCGG
TGGTGTTTGAAAGCGATGTGCAAGCTTTGTTAAATAATGCGGTGTTGCAGGAGGAAATCTTCGGCGCAGCATCCCTGGTG
GTGCGTTATGATTCCCCGGATCAACTTCACCAAGTAGCCAATTCACTCGAGGGACAATTAACTGCCACGATTCACGCATC
CCAGGATGATTTCCAGGAAGTCTCGGAAATTATCCCCCTCTTGGAGGATCTCGCGGGCCGTGTTCTTTATGGCGGCTGGC
CAACGGGTGTGGAAGTTGGGCACACGGTTATCCATGGAGGCCCTTATCCGGCGACCTCAAATGCGCAGTCGACAAGTGTT
GGAACCCTGGCAATCGAGAGATTTATGCGCCCGGTTTCTTATCAAACTTTCCCGGCTGAGCTGCTTCCAGATCCAGTTTC
TGAGGTAAATAAATGGGCTGTACCTCGGGAAATAGACCGTTAA

Upstream 100 bases:

>100_bases
CACCACTGCGTAACCTCTCCGAACAAGACATTGCAGATCTCTCCGACTTGCTCGCCACCTCTGGCGCAGGTTCTTACCGC
CTTCCAGTTGAGGTGAAAGC

Downstream 100 bases:

>100_bases
TAGCTGGTCTTTACATTTGACAGAAACCTCCGACAAAACCCCAATAGTTGACACGGAAACCAATTCATTCTAGCTTTAGT
GACCATGTCAACTACCAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MITATALHGCSLIDGEWVAGKNGEITGFDPRTNASLNPSYSLANRAQLRAATTSAKRAFESYRLTTPEVRADFLDSIADN
IDDLTEEIVQRASLETGLGTTRLTGEVARTSNQLRLFAETVRSGQFHRVRIERGPRIDLRQRQVPLGPVAVFGASNFPLA
FSTAGGDTASALAAGCPVVFKAHNAHPGTAELVGQAVRGAVEKHEFDAGVFNLVYGRGVEIGQELAADPNITAIGFTGSR
QGGLALSQTAFSRPVPVPVFAEMSATNPVFVFPGALADLDASSSLAEAFTASVTGSSGQLCTKPGLVFIPRGVAGDAFVE
LVAAKFKETTGQTMLTQGIAQAWQRGVDNLAAQPSVKILAQGTPGDGENAPGPVVFESDVQALLNNAVLQEEIFGAASLV
VRYDSPDQLHQVANSLEGQLTATIHASQDDFQEVSEIIPLLEDLAGRVLYGGWPTGVEVGHTVIHGGPYPATSNAQSTSV
GTLAIERFMRPVSYQTFPAELLPDPVSEVNKWAVPREIDR

Sequences:

>Translated_520_residues
MITATALHGCSLIDGEWVAGKNGEITGFDPRTNASLNPSYSLANRAQLRAATTSAKRAFESYRLTTPEVRADFLDSIADN
IDDLTEEIVQRASLETGLGTTRLTGEVARTSNQLRLFAETVRSGQFHRVRIERGPRIDLRQRQVPLGPVAVFGASNFPLA
FSTAGGDTASALAAGCPVVFKAHNAHPGTAELVGQAVRGAVEKHEFDAGVFNLVYGRGVEIGQELAADPNITAIGFTGSR
QGGLALSQTAFSRPVPVPVFAEMSATNPVFVFPGALADLDASSSLAEAFTASVTGSSGQLCTKPGLVFIPRGVAGDAFVE
LVAAKFKETTGQTMLTQGIAQAWQRGVDNLAAQPSVKILAQGTPGDGENAPGPVVFESDVQALLNNAVLQEEIFGAASLV
VRYDSPDQLHQVANSLEGQLTATIHASQDDFQEVSEIIPLLEDLAGRVLYGGWPTGVEVGHTVIHGGPYPATSNAQSTSV
GTLAIERFMRPVSYQTFPAELLPDPVSEVNKWAVPREIDR
>Mature_520_residues
MITATALHGCSLIDGEWVAGKNGEITGFDPRTNASLNPSYSLANRAQLRAATTSAKRAFESYRLTTPEVRADFLDSIADN
IDDLTEEIVQRASLETGLGTTRLTGEVARTSNQLRLFAETVRSGQFHRVRIERGPRIDLRQRQVPLGPVAVFGASNFPLA
FSTAGGDTASALAAGCPVVFKAHNAHPGTAELVGQAVRGAVEKHEFDAGVFNLVYGRGVEIGQELAADPNITAIGFTGSR
QGGLALSQTAFSRPVPVPVFAEMSATNPVFVFPGALADLDASSSLAEAFTASVTGSSGQLCTKPGLVFIPRGVAGDAFVE
LVAAKFKETTGQTMLTQGIAQAWQRGVDNLAAQPSVKILAQGTPGDGENAPGPVVFESDVQALLNNAVLQEEIFGAASLV
VRYDSPDQLHQVANSLEGQLTATIHASQDDFQEVSEIIPLLEDLAGRVLYGGWPTGVEVGHTVIHGGPYPATSNAQSTSV
GTLAIERFMRPVSYQTFPAELLPDPVSEVNKWAVPREIDR

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=439, Percent_Identity=24.1457858769932, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI25952152, Length=424, Percent_Identity=24.7641509433962, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4507229, Length=369, Percent_Identity=25.2032520325203, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI153266822, Length=442, Percent_Identity=25.3393665158371, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI25777721, Length=374, Percent_Identity=24.0641711229947, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI115387104, Length=440, Percent_Identity=23.1818181818182, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI21614513, Length=417, Percent_Identity=25.6594724220624, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789015, Length=434, Percent_Identity=26.9585253456221, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788042, Length=457, Percent_Identity=28.0087527352298, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081896, Length=424, Percent_Identity=29.0094339622642, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787558, Length=504, Percent_Identity=26.3888888888889, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787715, Length=436, Percent_Identity=27.5229357798165, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786504, Length=451, Percent_Identity=26.3858093126386, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787684, Length=388, Percent_Identity=27.0618556701031, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082295, Length=436, Percent_Identity=26.3761467889908, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787250, Length=387, Percent_Identity=27.1317829457364, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133930964, Length=327, Percent_Identity=27.5229357798165, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562198, Length=422, Percent_Identity=25.3554502369668, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25143874, Length=408, Percent_Identity=22.3039215686275, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25143876, Length=410, Percent_Identity=22.6829268292683, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71995613, Length=429, Percent_Identity=25.8741258741259, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71995606, Length=385, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115534176, Length=322, Percent_Identity=25.776397515528, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=441, Percent_Identity=26.0770975056689, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319478, Length=447, Percent_Identity=25.0559284116331, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323822, Length=317, Percent_Identity=29.3375394321767, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=25, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24666674, Length=427, Percent_Identity=25.0585480093677, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650465, Length=432, Percent_Identity=24.537037037037, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24585660, Length=436, Percent_Identity=23.6238532110092, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54960; Mature: 54960

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITATALHGCSLIDGEWVAGKNGEITGFDPRTNASLNPSYSLANRAQLRAATTSAKRAFE
CCEEEEECCCEEECCCEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SYRLTTPEVRADFLDSIADNIDDLTEEIVQRASLETGLGTTRLTGEVARTSNQLRLFAET
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHCCHHHHHHHHH
VRSGQFHRVRIERGPRIDLRQRQVPLGPVAVFGASNFPLAFSTAGGDTASALAAGCPVVF
HHCCCEEEEEECCCCCCCHHHCCCCCCCEEEECCCCCCEEEECCCCCHHHHHHHCCCEEE
KAHNAHPGTAELVGQAVRGAVEKHEFDAGVFNLVYGRGVEIGQELAADPNITAIGFTGSR
EECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCEEEEEECCCC
QGGLALSQTAFSRPVPVPVFAEMSATNPVFVFPGALADLDASSSLAEAFTASVTGSSGQL
CCCEEEEHHHCCCCCCCCEEEECCCCCCEEECCCCHHCCCCCHHHHHHHHHCCCCCCCCE
CTKPGLVFIPRGVAGDAFVELVAAKFKETTGQTMLTQGIAQAWQRGVDNLAAQPSVKILA
ECCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
QGTPGDGENAPGPVVFESDVQALLNNAVLQEEIFGAASLVVRYDSPDQLHQVANSLEGQL
ECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCEE
TATIHASQDDFQEVSEIIPLLEDLAGRVLYGGWPTGVEVGHTVIHGGPYPATSNAQSTSV
EEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCEEEECCCCCCCCCCCCCCH
GTLAIERFMRPVSYQTFPAELLPDPVSEVNKWAVPREIDR
HHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHCCCCHHCCC
>Mature Secondary Structure
MITATALHGCSLIDGEWVAGKNGEITGFDPRTNASLNPSYSLANRAQLRAATTSAKRAFE
CCEEEEECCCEEECCCEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SYRLTTPEVRADFLDSIADNIDDLTEEIVQRASLETGLGTTRLTGEVARTSNQLRLFAET
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHCCHHHHHHHHH
VRSGQFHRVRIERGPRIDLRQRQVPLGPVAVFGASNFPLAFSTAGGDTASALAAGCPVVF
HHCCCEEEEEECCCCCCCHHHCCCCCCCEEEECCCCCCEEEECCCCCHHHHHHHCCCEEE
KAHNAHPGTAELVGQAVRGAVEKHEFDAGVFNLVYGRGVEIGQELAADPNITAIGFTGSR
EECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCEEEEEECCCC
QGGLALSQTAFSRPVPVPVFAEMSATNPVFVFPGALADLDASSSLAEAFTASVTGSSGQL
CCCEEEEHHHCCCCCCCCEEEECCCCCCEEECCCCHHCCCCCHHHHHHHHHCCCCCCCCE
CTKPGLVFIPRGVAGDAFVELVAAKFKETTGQTMLTQGIAQAWQRGVDNLAAQPSVKILA
ECCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
QGTPGDGENAPGPVVFESDVQALLNNAVLQEEIFGAASLVVRYDSPDQLHQVANSLEGQL
ECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCEE
TATIHASQDDFQEVSEIIPLLEDLAGRVLYGGWPTGVEVGHTVIHGGPYPATSNAQSTSV
EEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCEEEECCCCCCCCCCCCCCH
GTLAIERFMRPVSYQTFPAELLPDPVSEVNKWAVPREIDR
HHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]