Click here to switch to the map view.

The map label for this gene is aroQ

Identifier: 145294542

GI number: 145294542

Start: 551197

End: 551634

Strand: Direct

Name: aroQ

Synonym: cgR_0494

Alternate gene names: 145294542

Gene position: 551197-551634 (Clockwise)

Preceding gene: 145294541

Following gene: 145294543

Centisome position: 16.63

GC content: 57.31

Gene sequence:

>438_bases
ATGCTTGGAAAAATTCTCCTCCTCAACGGCCCAAACCTGAACATGCTGGGCAAACGCGAGCCTGACATTTACGGACACGA
CACCTTGGAAGACGTCGTCGCGCTGGCAACCGCTGAGGCTGCGAAGCACGGCCTTGAGGTTGAGGCGCTGCAGAGCAATC
ACGAAGGTGAGCTAATCGATGCGCTGCACAACGCTCGCGGCACCCACATCGGTTGCGTGATTAACCCCGGCGGCCTGACT
CACACTTCGGTGGCGCTTTTGGATGCGGTGAAGGCGTCTGAGCTTCCTACCGTTGAGGTGCACATTTCCAATCCGCATGC
CCGTGAAGAGTTCCGCCACCATTCTTACATTTCCCTCGCCGCGGTCTCCGTTATCGCTGGCGCTGGCATCCAGGGTTACC
GTTTCGCGGTCGATATCCTGGCAAATCTCAAAAAGTAG

Upstream 100 bases:

>100_bases
TTAGCGGCGCAGTATCGTGAGGTGCGGGACCTCGAGCGGGGAATCCCCAACTAGCATCCCGAACTAGCCCCCCCAACAAC
AATTAGAAAAGGAACCTAAA

Downstream 100 bases:

>100_bases
AAAGCCCAAAAAATATGAACGACAGTATTCTCCTCGGCCTAATCGGCCAGGGCCTCGACCTATCGCGCACCCCCGCAATG
CACGAGGCGGAAGGCCTCGC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLT
HTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK

Sequences:

>Translated_145_residues
MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLT
HTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK
>Mature_145_residues
MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLT
HTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_CORGB (A4QB64)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137363.1
- ProteinModelPortal:   A4QB64
- SMR:   A4QB64
- STRING:   A4QB64
- GeneID:   4993973
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0494
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   EFRQTNH
- ProtClustDB:   PRK13015
- BioCyc:   MetaCyc:MONOMER-15335
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15464; Mature: 15464

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELID
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
ALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLA
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCHHHHH
AVSVIAGAGIQGYRFAVDILANLKK
HHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELID
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
ALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLA
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCHHHHH
AVSVIAGAGIQGYRFAVDILANLKK
HHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA