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The map label for this gene is regX3 [H]

Identifier: 145294521

GI number: 145294521

Start: 532265

End: 532963

Strand: Direct

Name: regX3 [H]

Synonym: cgR_0476

Alternate gene names: 145294521

Gene position: 532265-532963 (Clockwise)

Preceding gene: 145294520

Following gene: 145294522

Centisome position: 16.06

GC content: 55.36

Gene sequence:

>699_bases
ATGACGACAATCCTGATCGTTGAAGATGAGGAATCGTTAGCAGATCCTTTGGCCTTTCTTCTTCGCAAAGAAGGTTTTGA
CACCATCATCGCCGGTGATGGCCCAACCGCTCTTGTGGAGTTCAGTCGCAACGAAATCGATATCGTCCTCTTAGACCTCA
TGCTCCCAGGCATGTCTGGCACCGACGTATGCAAAGAACTCCGCAGCGTATCCACTGTTCCCGTCATCATGGTCACCGCC
CGCGACTCCGAGATCGACAAAGTTGTTGGTCTCGAACTCGGCGCCGATGATTATGTAACCAAGCCATATTCTTCCCGCGA
ACTCATCGCCCGCATCCGCGCTGTCCTGCGCCGACGCGGAGTTACTGAAACCGAAGCCGAAGAATTACCACTTGACGATC
AAATCCTCGAAGGCGGCCGCGTCCGCATGGACGTCGATTCCCACACCGTCACCGTCGACGGCGAACCAGTGAGCATGCCA
CTGAAGGAATTCGACCTTCTGGAGTACCTCCTCCGCAACGCCGGCCGAGTCCTCACCCGCGGACAGCTCATCGACCGAAT
TTGGGGCGCAGATTACGTCGGCGACACCAAAACCCTCGACGTTCATGTCAAAAGGTTGCGTTCCAAGATCGAAGAAGAGC
CATCTCGACCTCGTTACCTCGTGACCGTGCGTGGATTGGGCTACAAATTCGAGCTGTAG

Upstream 100 bases:

>100_bases
CAGAGTCCAAGGAACCGGCAGGATCTAAGCAGGGACCTAGTTTGGATTCACCTATTCGTACGACTGCGTCCAAAGCATCT
GGGCGCCGAAAGGAAAAATC

Downstream 100 bases:

>100_bases
GGCTCTGCTGGGCTTAGTTGGGCGCTCAACTTAGTTAAAACCAGACACACGTGCCCGCGGTTCGGGTTTTCCGAGTTGGT
GGGCACTCTGGTTTGGTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTTILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSGTDVCKELRSVSTVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRGVTETEAEELPLDDQILEGGRVRMDVDSHTVTVDGEPVSMP
LKEFDLLEYLLRNAGRVLTRGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKFEL

Sequences:

>Translated_232_residues
MTTILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSGTDVCKELRSVSTVPVIMVTA
RDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRGVTETEAEELPLDDQILEGGRVRMDVDSHTVTVDGEPVSMP
LKEFDLLEYLLRNAGRVLTRGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKFEL
>Mature_231_residues
TTILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSGTDVCKELRSVSTVPVIMVTAR
DSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRGVTETEAEELPLDDQILEGGRVRMDVDSHTVTVDGEPVSMPL
KEFDLLEYLLRNAGRVLTRGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKFEL

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.4347826086956, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=37.9310344827586, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=37.5, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=36.5638766519824, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=37.5, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=35.0877192982456, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=36.5217391304348, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=34.061135371179, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=37.6068376068376, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=36.7256637168142, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=36.8421052631579, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=35.3982300884956, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=31.304347826087, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=30.0429184549356, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=41.5094339622642, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26003; Mature: 25872

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSG
CEEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCEEEEEEEECCCCCCH
TDVCKELRSVSTVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRG
HHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
VTETEAEELPLDDQILEGGRVRMDVDSHTVTVDGEPVSMPLKEFDLLEYLLRNAGRVLTR
CCCCCHHHCCCCHHHHCCCEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHH
GQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKFEL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure 
TTILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSG
EEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCEEEEEEEECCCCCCH
TDVCKELRSVSTVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRG
HHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
VTETEAEELPLDDQILEGGRVRMDVDSHTVTVDGEPVSMPLKEFDLLEYLLRNAGRVLTR
CCCCCHHHCCCCHHHHCCCEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHH
GQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKFEL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA