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The map label for this gene is dnaX [H]

Identifier: 145294443

GI number: 145294443

Start: 433424

End: 434683

Strand: Direct

Name: dnaX [H]

Synonym: cgR_0398

Alternate gene names: 145294443

Gene position: 433424-434683 (Clockwise)

Preceding gene: 145294441

Following gene: 145294445

Centisome position: 13.08

GC content: 57.86

Gene sequence:

>1260_bases
GTGACTAATTCGAGTGTGTTTGACAGTCTCGCCGGCTCCAAAACAGTGTCCAAGACGCTTTTCGACGCGGCCTCCAGCGC
GCGTGCCCTTGTCCGCGCCCGAACCACAGAACGTGCCCGCGCCCGGGCAGAACACCAAAACCCTGCAATGATCCACGACT
CCGGCTTCGCCCAGTCATGGCTGTTTACAGGCCCTCCCGGATCGGGACGTTCTGTGGCAGCCAAGGTTTTCGCCGCTACG
CTCGTATGTTCGAATCCGGATGTTGTGGGCTGTGGACAATGCGAGGATTGCCGCGCCGCCATGGGAGGCAGCCACCCCGA
TATTGAACACATCGTCCCGCAGCAACTGTCCATCGGTGTTGATGCAGCTAGAGAGGTCATCAAAGCCGCAGCGGTCAGTC
CTGTTGCAGGAAACTGGCGAGTCGTCATCTTCGAAAACGCCGACCGACTCACCATGCAAGCCGCCAACGCCTTGCTGAAA
ACCGTGGAGGAACCAACCGAAAGCACCGTGATGATTCTGTGCGCACCCACCACAGACCCCCGCGACATTGCGATCACCCT
CCGCTCCCGCTGCAGGCACCTCTACATTCCCACCCCCTCCATCGCGGAAGTCGCACGAATCCTCGTAGCTGAAGGCAACG
TCAGCCAAGCGGATGCAGAATTAGCGGCGGCTGCTTCAGGAGCTCACATCGGCAGGGCTCGATACTTAGCCCACAACAAC
GCCGCCCAACGCAGACGCGCCAGCATCCTCAACCTGGCTGAATTAATCTTCCACGGCGATGTCGCCTTCCGCTCCGTAAA
CACCTTGGTCAAAATGGTGGAAACCGAAGCCAAAGACAGCAACAAAGAAAAAGAAGAAGCCGAACTCGAAGCCGTAAGAA
TCTCACTCGGCATGGGAGCCAAAGGCAAAGGTGTCCACAAAGCAGTACGTGGAGGAGCGGGAGATTTCAAAGCACTCGAA
GACCAACAAAAACTCCGACGCACCCGATTCCTCCGCGACAGCCTCGACCTCGCACTCGTCGACCTAGCCGGCATCTACCG
CGATGCCATCATCATTTCCTCCCAAGCCCAAGTCGGACTCACACACCCCGATATGGAAGGCCTCTCCCAAGAACTCGCAA
CAAAAGTAAGCCAAGAAGGACTCCTGGCATGCCTCGACGCGATCTCCAAATGCCGCGAATCCTTCGGCTTCAATGTACGA
CCCATCGTGGCCATGGACGCCCTGGTAGGACGCCTGCGCAAAGCCTATAAAGTGTCCTAA

Upstream 100 bases:

>100_bases
CCACAGCCATTTCAATGCTCTAAGCAATCGACTCATGCTCAATACTCTAACGTGCCGGTGCGACATCGCGAGGATGTAGT
GAGGAAGTAGTGTAGAGATC

Downstream 100 bases:

>100_bases
ACACCCCAAATTATTGAAGTCAAGAACACATCAGGTAAAGTAGCCAATCGGTAAATAGTGAAGTTAAATTTCCACAGTAT
TTCCGTGCCGCTTTAGCTCA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTNSSVFDSLAGSKTVSKTLFDAASSARALVRARTTERARARAEHQNPAMIHDSGFAQSWLFTGPPGSGRSVAAKVFAAT
LVCSNPDVVGCGQCEDCRAAMGGSHPDIEHIVPQQLSIGVDAAREVIKAAAVSPVAGNWRVVIFENADRLTMQAANALLK
TVEEPTESTVMILCAPTTDPRDIAITLRSRCRHLYIPTPSIAEVARILVAEGNVSQADAELAAAASGAHIGRARYLAHNN
AAQRRRASILNLAELIFHGDVAFRSVNTLVKMVETEAKDSNKEKEEAELEAVRISLGMGAKGKGVHKAVRGGAGDFKALE
DQQKLRRTRFLRDSLDLALVDLAGIYRDAIIISSQAQVGLTHPDMEGLSQELATKVSQEGLLACLDAISKCRESFGFNVR
PIVAMDALVGRLRKAYKVS

Sequences:

>Translated_419_residues
MTNSSVFDSLAGSKTVSKTLFDAASSARALVRARTTERARARAEHQNPAMIHDSGFAQSWLFTGPPGSGRSVAAKVFAAT
LVCSNPDVVGCGQCEDCRAAMGGSHPDIEHIVPQQLSIGVDAAREVIKAAAVSPVAGNWRVVIFENADRLTMQAANALLK
TVEEPTESTVMILCAPTTDPRDIAITLRSRCRHLYIPTPSIAEVARILVAEGNVSQADAELAAAASGAHIGRARYLAHNN
AAQRRRASILNLAELIFHGDVAFRSVNTLVKMVETEAKDSNKEKEEAELEAVRISLGMGAKGKGVHKAVRGGAGDFKALE
DQQKLRRTRFLRDSLDLALVDLAGIYRDAIIISSQAQVGLTHPDMEGLSQELATKVSQEGLLACLDAISKCRESFGFNVR
PIVAMDALVGRLRKAYKVS
>Mature_418_residues
TNSSVFDSLAGSKTVSKTLFDAASSARALVRARTTERARARAEHQNPAMIHDSGFAQSWLFTGPPGSGRSVAAKVFAATL
VCSNPDVVGCGQCEDCRAAMGGSHPDIEHIVPQQLSIGVDAAREVIKAAAVSPVAGNWRVVIFENADRLTMQAANALLKT
VEEPTESTVMILCAPTTDPRDIAITLRSRCRHLYIPTPSIAEVARILVAEGNVSQADAELAAAASGAHIGRARYLAHNNA
AQRRRASILNLAELIFHGDVAFRSVNTLVKMVETEAKDSNKEKEEAELEAVRISLGMGAKGKGVHKAVRGGAGDFKALED
QQKLRRTRFLRDSLDLALVDLAGIYRDAIIISSQAQVGLTHPDMEGLSQELATKVSQEGLLACLDAISKCRESFGFNVRP
IVAMDALVGRLRKAYKVS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=148, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787341, Length=198, Percent_Identity=33.8383838383838, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44863; Mature: 44732

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSSVFDSLAGSKTVSKTLFDAASSARALVRARTTERARARAEHQNPAMIHDSGFAQSW
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
LFTGPPGSGRSVAAKVFAATLVCSNPDVVGCGQCEDCRAAMGGSHPDIEHIVPQQLSIGV
EEECCCCCCHHHHHHHHHHHHEECCCCEEECCCCHHHHHHHCCCCCCHHHHCCHHHHCCH
DAAREVIKAAAVSPVAGNWRVVIFENADRLTMQAANALLKTVEEPTESTVMILCAPTTDP
HHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
RDIAITLRSRCRHLYIPTPSIAEVARILVAEGNVSQADAELAAAASGAHIGRARYLAHNN
CCEEEEEHHCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCC
AAQRRRASILNLAELIFHGDVAFRSVNTLVKMVETEAKDSNKEKEEAELEAVRISLGMGA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCCC
KGKGVHKAVRGGAGDFKALEDQQKLRRTRFLRDSLDLALVDLAGIYRDAIIISSQAQVGL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
THPDMEGLSQELATKVSQEGLLACLDAISKCRESFGFNVRPIVAMDALVGRLRKAYKVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNSSVFDSLAGSKTVSKTLFDAASSARALVRARTTERARARAEHQNPAMIHDSGFAQSW
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
LFTGPPGSGRSVAAKVFAATLVCSNPDVVGCGQCEDCRAAMGGSHPDIEHIVPQQLSIGV
EEECCCCCCHHHHHHHHHHHHEECCCCEEECCCCHHHHHHHCCCCCCHHHHCCHHHHCCH
DAAREVIKAAAVSPVAGNWRVVIFENADRLTMQAANALLKTVEEPTESTVMILCAPTTDP
HHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
RDIAITLRSRCRHLYIPTPSIAEVARILVAEGNVSQADAELAAAASGAHIGRARYLAHNN
CCEEEEEHHCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCC
AAQRRRASILNLAELIFHGDVAFRSVNTLVKMVETEAKDSNKEKEEAELEAVRISLGMGA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCCC
KGKGVHKAVRGGAGDFKALEDQQKLRRTRFLRDSLDLALVDLAGIYRDAIIISSQAQVGL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
THPDMEGLSQELATKVSQEGLLACLDAISKCRESFGFNVRPIVAMDALVGRLRKAYKVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]