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The map label for this gene is arsB [H]

Identifier: 145294384

GI number: 145294384

Start: 376815

End: 377996

Strand: Direct

Name: arsB [H]

Synonym: cgR_0339

Alternate gene names: 145294384

Gene position: 376815-377996 (Clockwise)

Preceding gene: 145294381

Following gene: 145294385

Centisome position: 11.37

GC content: 48.48

Gene sequence:

>1182_bases
GTGGATGGGCGCGGTCATGTCCGTCATTATATATTGACGTACATCGATATCGAAGGTATTTTTATATCGACAAACATCAA
TATGATTGAAAGCTGGCTCATGACCCTTACTAAAGAGCATTCGACACCTCGAGCGGCTGGCTCAATGTCGTTTCTTGACC
GCTGGTTAGCTGCCTGGATTTTCTTGGCTATGGCTGCTGGGTTGTTAATCGGCAAGGTCTTTCCAGGAATTGGGGCGCTT
TTGAGCGCGGTGGAAATTGGTGGAATTTCCATTCCAATTGCTATCGGTTTGATCGTCATGATGTATCCAACTTTGGCCAA
GGTGCGCTACGACAAAACTAAAGAAATCACCACAGACCGCACTCTCATGGTGGTGTCGATTATGTTGAACTGGATCGTTG
GACCAGCACTTATGTTTAGCCTGGCGTGGCTGTTTCTTCCAGATCAACCAGAGCTTCGCACTGGGCTAATTATCGTGGGC
CTTGCGCGCTGTATCGCGATGGTTTTGGTATGGAGTGATCTCGCTTGTGGTGACCGGGAAGCAACTGCTGTGCTGGTTGC
AATCAACTCGGTGTTCCAGATCCTTATGTTCGGTGTGCTTGGTTGGTTTTACCTGCAGATTCTTCCCTCGTGGCTGGGAT
TAGACACCACGTCGGTGACTTTCTCTGTGGTATCAATCGTGACTTCCGTTCTCGTGTTCTTGGGCATGCCACTTGTAGCT
GGAGTTTTATCTCGCGTCATTGGTGAAAAAATAAAGGGACGGCGCTGGTACGAGGACACGTTCCTGCCTAAGATTTCACC
CTTGGCGCTGATTGGCTTGCTATACACAATTGTTCTGCTGTTTTCTTTGCAGGGGGATGAAATCACAGCGCAGCCTTGGA
CAGTAGCTCGTCTTGCATTGCCGCTGCTGATGTACTTTGCGGGCATGTTTTTCATTTCCCTGGTGGTATCCAAACTGTCC
GGGTTAACTTATGAGCGAGCTGCTTCCGTGTCTTTTACTGCAGCAGGAAACAACTTTGACTTAGCGATTGCGGTATCGAT
CGGAACCTTTGGTGCGACATCACCGCAGGCATTAGCTGGAACGATCGGCCCTTTGATTGAAGTCCCAGTATTAGTCGGAT
TGGTTTATGCCATGTTGTGGCTTGGACCAAAAATCTTTAAAAAGGAGAATGCAGGATCATGA

Upstream 100 bases:

>100_bases
TCACCGAGCACTTTGAAAATCTCGGCATAGCGTTCGGCATCGTCCACGCTGAGTGGTTCTGCTGCCAGTGGGCAACACTC
TGCGGAGTTAATGAGCGGTA

Downstream 100 bases:

>100_bases
AATCAGTTTTGTTTGTGTGCGTCGGTAATGGCGGAAAATCACAGATGGCGGCGTCGCTGGCACAGAAGTATGCATCAGAT
TCAGTAGAGATCCATTCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDGRGHVRHYILTYIDIEGIFISTNINMIESWLMTLTKEHSTPRAAGSMSFLDRWLAAWIFLAMAAGLLIGKVFPGIGAL
LSAVEIGGISIPIAIGLIVMMYPTLAKVRYDKTKEITTDRTLMVVSIMLNWIVGPALMFSLAWLFLPDQPELRTGLIIVG
LARCIAMVLVWSDLACGDREATAVLVAINSVFQILMFGVLGWFYLQILPSWLGLDTTSVTFSVVSIVTSVLVFLGMPLVA
GVLSRVIGEKIKGRRWYEDTFLPKISPLALIGLLYTIVLLFSLQGDEITAQPWTVARLALPLLMYFAGMFFISLVVSKLS
GLTYERAASVSFTAAGNNFDLAIAVSIGTFGATSPQALAGTIGPLIEVPVLVGLVYAMLWLGPKIFKKENAGS

Sequences:

>Translated_393_residues
MDGRGHVRHYILTYIDIEGIFISTNINMIESWLMTLTKEHSTPRAAGSMSFLDRWLAAWIFLAMAAGLLIGKVFPGIGAL
LSAVEIGGISIPIAIGLIVMMYPTLAKVRYDKTKEITTDRTLMVVSIMLNWIVGPALMFSLAWLFLPDQPELRTGLIIVG
LARCIAMVLVWSDLACGDREATAVLVAINSVFQILMFGVLGWFYLQILPSWLGLDTTSVTFSVVSIVTSVLVFLGMPLVA
GVLSRVIGEKIKGRRWYEDTFLPKISPLALIGLLYTIVLLFSLQGDEITAQPWTVARLALPLLMYFAGMFFISLVVSKLS
GLTYERAASVSFTAAGNNFDLAIAVSIGTFGATSPQALAGTIGPLIEVPVLVGLVYAMLWLGPKIFKKENAGS
>Mature_393_residues
MDGRGHVRHYILTYIDIEGIFISTNINMIESWLMTLTKEHSTPRAAGSMSFLDRWLAAWIFLAMAAGLLIGKVFPGIGAL
LSAVEIGGISIPIAIGLIVMMYPTLAKVRYDKTKEITTDRTLMVVSIMLNWIVGPALMFSLAWLFLPDQPELRTGLIIVG
LARCIAMVLVWSDLACGDREATAVLVAINSVFQILMFGVLGWFYLQILPSWLGLDTTSVTFSVVSIVTSVLVFLGMPLVA
GVLSRVIGEKIKGRRWYEDTFLPKISPLALIGLLYTIVLLFSLQGDEITAQPWTVARLALPLLMYFAGMFFISLVVSKLS
GLTYERAASVSFTAAGNNFDLAIAVSIGTFGATSPQALAGTIGPLIEVPVLVGLVYAMLWLGPKIFKKENAGS

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=328, Percent_Identity=35.3658536585366, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 42747; Mature: 42747

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRGHVRHYILTYIDIEGIFISTNINMIESWLMTLTKEHSTPRAAGSMSFLDRWLAAWI
CCCCHHHHHHEEEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FLAMAAGLLIGKVFPGIGALLSAVEIGGISIPIAIGLIVMMYPTLAKVRYDKTKEITTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
TLMVVSIMLNWIVGPALMFSLAWLFLPDQPELRTGLIIVGLARCIAMVLVWSDLACGDRE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ATAVLVAINSVFQILMFGVLGWFYLQILPSWLGLDTTSVTFSVVSIVTSVLVFLGMPLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVLSRVIGEKIKGRRWYEDTFLPKISPLALIGLLYTIVLLFSLQGDEITAQPWTVARLAL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
PLLMYFAGMFFISLVVSKLSGLTYERAASVSFTAAGNNFDLAIAVSIGTFGATSPQALAG
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCEEEEEEEEECCCCCCCCHHHHH
TIGPLIEVPVLVGLVYAMLWLGPKIFKKENAGS
HHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCC
>Mature Secondary Structure
MDGRGHVRHYILTYIDIEGIFISTNINMIESWLMTLTKEHSTPRAAGSMSFLDRWLAAWI
CCCCHHHHHHEEEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
FLAMAAGLLIGKVFPGIGALLSAVEIGGISIPIAIGLIVMMYPTLAKVRYDKTKEITTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
TLMVVSIMLNWIVGPALMFSLAWLFLPDQPELRTGLIIVGLARCIAMVLVWSDLACGDRE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ATAVLVAINSVFQILMFGVLGWFYLQILPSWLGLDTTSVTFSVVSIVTSVLVFLGMPLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVLSRVIGEKIKGRRWYEDTFLPKISPLALIGLLYTIVLLFSLQGDEITAQPWTVARLAL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
PLLMYFAGMFFISLVVSKLSGLTYERAASVSFTAAGNNFDLAIAVSIGTFGATSPQALAG
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCEEEEEEEEECCCCCCCCHHHHH
TIGPLIEVPVLVGLVYAMLWLGPKIFKKENAGS
HHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]