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The map label for this gene is dhbF [H]

Identifier: 145294363

GI number: 145294363

Start: 348307

End: 352272

Strand: Direct

Name: dhbF [H]

Synonym: cgR_0318

Alternate gene names: 145294363

Gene position: 348307-352272 (Clockwise)

Preceding gene: 145294362

Following gene: 145294364

Centisome position: 10.51

GC content: 57.03

Gene sequence:

>3966_bases
ATGAGCACTCAGGACCATCCGAAGTATGCGGTCTATGGCGTGGAGGCTCCTCCGCCGGAGTGCACTCTGATTGACATTGT
TGATGCCACCGTTGCAATGTACCCGGAAGTTCGTGGACTGGAAGGCACCAACGGCACCTTAACCTACTCAGAGCTACGTG
ACACGATTGAGGTGGAGGTGAGCAGGCTCCGCTCCGCAGGGGTTGGACGTGGAGATCGAGTAGGAATCCGGGTCCCCTCC
GGAACTGTCGATCTTTACGTCGCAATTTTGGCCACCCTCTACGCCGGTGCAGCTTATGTACCTGTGGACTGGGATGAATC
TGATTCCAGAGCTCAGACGGTGTGGGAGGAAGCGGATGTCGCGGTAGTCTACGGTCTAAGCCTTAGCATCGATGTCCGCC
GTCATGAACCTAACACTGATCACAGTCGTGCCACCCTAGATGATGATGCCTGGATAATCTTCACATCTGGAACCACAGGT
AAGCCAAAAGGTGTCGCCATCACGCACCGCTCCGCTGCTGCGCTAGTCGAATCGGAACGGCTGCTTTACCTGGTTGATGC
ACCGCTGGGACCACAAGACCGAGTCATGGGAGGACTCTCGGTAGCCTTCGATGCCTCTTGTGAAGAAATGTGGCTCGCCT
GGCGTAACGGCTCCACACTGGTGGCGGCTCCGCGTGATCTTGTGCGCTCCGGAGAAGAACTAGGACAGTGGATTGTCGAT
GAGAAAATCACCGCGGTGTCTACCGTGCCAACACTCGCGGCGATGTGGGATCCCGATTCCCTCACCGCGGTTCGACTACT
GATCTTTGGGGGGGAGGCATGCCCGCTCCCATTGATCGAAAAGCTCTTCGTGCCAGGTAGAGAACTGTGGAACACCTACG
GGCCGACCGAGACCACAGTGATCGTCAGCGGTCAGCTGATGACTCCGGAACCGCCGGTGCGGATCGGTCGTCCCATCGTT
GGCTGGGAACTCGCGGTGGTCAATGAGGACGGCATTCCGGTGAACTGGGGTGAAACGGGTGAGCTGGTTGTCGGAGGTAT
TGGCCTCGGCCGCTATCTCGATGAAGAGAAGGACCGGGAATCCTACAGGGCTCTGCCAGCCTTAGGGTGGAACCGTTCCT
ATCACACCGGCGACCTGGTAAAAGCCGAGCCAGAGGGGCTCATCTTCGCTGGACGGGTCGACGACCAGATCAAGATCGGT
GGTCGGCGTCTGGAGCTGGGCGAGGTGGATGGCTACCTTAACGACATCCCTGGTGTCGATGCTGCCGCAGCTGCGGTGCG
CACCACCGAGTCCGGTAACGATGTGCTGGTGGGATATCTTTCTGGTGCAGATCCAGATGCAATCGACCTGCAGCAGGCCC
GTAAGTTAGTCGCAGAGAAGATGCCCAAAGGTGTTGTTCCTTTATTGTGCGTTCTCGATGAGCTACCCATGAAGACCTCC
GGCAAGGTGGACCGCAAAGCCCTGCCTTGGCCTTTGGCTACCCAACAGGACACTGGTGGGCTTCCGGAGCGTTACGCTGC
CCTCGGTGAACTTTGGATAGAGCAGCTTGGTCCGGTGTCGCTGACCTCAGACTCCAACTTCTTCGAACTCGGCGGTGGTT
CTGTCGCAGTGGCTCGATTGGCTGCCCGTATCCGCGAGACCCACCCCGGGGCGGAGATCGGTGAGCTTTACCAGAATCCT
TTCCTGGGAAGGATGTCGCACTACCTGGAGAGCCTGGTGTCGGATTCTGAGGAACGACCGATGCCAAAGCGTATCCCGCG
GATAGGAGTTCTGTTCCAGGGCTTTTGGGTGTTATTCCTCTACCTGATTAATGCGCTGCGCTACGTCACTGGCGTCCTAA
TTGTGGTGTGGCTCTTGGAGCGGTTCTTCGATGCAGGCTGGGTTCCTGGAATCTCCGGATTCCCGCTGTTGATTGCCTGG
CTGGTGCTGTATTCATTGCCTGGCAAGGTGATGATTACGGCTCTGATCACTCGTCCGCTGACATTCCGGATGAAGGCGGG
TCGTTACCGGCGCGGCGGATGGACGCACCTGAGGCTATGGGCGTCGCAACGCACTCTGACTTTCATGCAGTTGGAGAACC
TGAACGGCACACCCTTCGCGCCGATGATGCACCGTCTTTTGGGAACGAAAGTGGGACGGAATACCAGCCTCTCCCATTCT
CCTTCGGTCACTGGACTGCTGACCATCGAGAAAGGAGCGACGGTCGAGTTTGAAGCGGATCTGGAAGGGTACTGGATTGA
TGGTGACACTCTAATTGTGGACACCATCACGATCGGAGAAAATGTACGTGTCGGTGCACGCAGCATCATCCAACCTGGGG
TGCGAATCGCGCCGGGGGCGGAGATCCTGCCAGGCACCAACGTGGACCGTGACATCGAAGGCCCTGAAACGTGGAGTGGC
TCTCCGATGACCTATCAAGGGCCAGCAGGTGAAACCTGGCCTGCGACCACCCCAAGCAACACCCGGGAAACTCCGGTGAT
GGGTAGGCTTCGTTCTGGACTGACTTACGGTGGTGGTCTGCTGGTGCTTCGAATACTTCAGGTGGCGGCGCTAGTTCCGG
GGTTCATGCTGGTTTTCCCATTTGTCTCCCGTCTAGAGTTCTATGAACTGGTGTTCCCAATCCTGATAGTGTGGGTGCCT
GTTTTCACTATTCTCATGGTGTTCACCTGGCTTCTGGGCGTGGTGATAGTTATTCGGATACTGTCTGTGTTCATTCGGCC
TGGATATTTCCCACAGCGCAGTTTTACCGGATTTGCGGTTTGGCTCACGCACACCCTGATGCAGCGCACGCTGATTTCCA
CGTATCCAATCTATGCTTCCAGTTTCACTCCGCTGTGGTTCCGCTTGCTAGGCGCCCGGGTAGGCAAAAACGTTGAGATC
TCCACTGTGGAGACGATCCCGCACCTAACCTGGATCCGAAGTGGCAGTTTTCTGGCTGACCATGCGCTGGCTAATTCCAC
ACGGATGTGTCGGGGCTGGTTGCATGTTGGCACAACAGTGATTGGTGAAGGCAGCTTCGTCGGTAATTCAGCAATTGTTG
GCCCGGACCGTGATGTGTCCGACGGAGCCTTGATGGCGGTGCTGTCCACGGCACCGTACCATCCGGAAGCTGGAAGCTCG
TGGTTGGGACGACATCCGATGCAGATCACCCGGCAACGAGTCAAGGGCGAGGACAGCCTGACATATAAGCCGCCATTTCA
GAGGAAGGTGCTGCGGGCGGGGGTTGAACTCTGCCGAATTATACCAGCGATGATCAGTAACTGGATGGATCTACTGAGTG
TGTACATCCTCACCTCCATCTACATGTACTACTGGCTGGGTGGGGAGACTCAACTTGATTCTCTGATGTTCGCGTCTTTG
TGGTCGTGGCCGGTGCTGGTGGCTTCAGGATCTCTTGCCGCGTTGGTTGCGCTGATCGCTAAATGGCTGCTCGTAGGCAG
ATTCCGGGAACGTAGCGTGCCGCTGTTCAGTTCACTGGTGTGGCGCGGGGAGCTCGCTGATGTCTTCATCGAGTCCCTCG
CAATTCCTGGATTCGTCCGGATGAGTCTGGGCACTCCGATGCTCAATCTGTGGCACCGCTGTCTGGGCGTGAAGATCGGC
CGGAGCGTGTGGTGTGAGACCTGGTGGCTTCCAGAATTTGATCTCATCAGAATCTCAGACCTCGCTTCCGTCAACCGTGG
CACTGTGCTGCAGACCCATCTTTTTCATGACCGCGTCATGTCCATGGAACCCGTCGTCTTGGAGGATGGTGCGACGTTGG
GGCCCAACAGTTTTGTTCTTCCGGGTGCTGTGATCGGGGAGTGCACGACAGTGAGGACGGGGTCATTAGTGCAACGTCAG
GAAGCCCTCCCTGATAACAGTGAGTGGGCAGGTAACCCCGTGCGTTATCTCGGCAGCACATCCAGTAACGCCGGTAGAGC
AGAAACCGGGCAGGAAACCCTAGTTATGGAAGGTGAAGATCAATGA

Upstream 100 bases:

>100_bases
CAATTACCCAGGGTGACCAGGCAGGGAACTCCTACCAAAGTGCTCCTCGTGGCCTCGGATTCCGACAAAACGCTCTGGTT
GCGATCGCGACGAGGGAATC

Downstream 100 bases:

>100_bases
CGAGCCATTTGGAAGAGAAACAGGTGCGAGTCCTGGAAGGAGACCTTCCGGTAGATGTTCGACCTCATTCTGGCTGGAGT
GAAGAACGTTCGGTATGGAC

Product: hypothetical protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1321; Mature: 1320

Protein sequence:

>1321_residues
MSTQDHPKYAVYGVEAPPPECTLIDIVDATVAMYPEVRGLEGTNGTLTYSELRDTIEVEVSRLRSAGVGRGDRVGIRVPS
GTVDLYVAILATLYAGAAYVPVDWDESDSRAQTVWEEADVAVVYGLSLSIDVRRHEPNTDHSRATLDDDAWIIFTSGTTG
KPKGVAITHRSAAALVESERLLYLVDAPLGPQDRVMGGLSVAFDASCEEMWLAWRNGSTLVAAPRDLVRSGEELGQWIVD
EKITAVSTVPTLAAMWDPDSLTAVRLLIFGGEACPLPLIEKLFVPGRELWNTYGPTETTVIVSGQLMTPEPPVRIGRPIV
GWELAVVNEDGIPVNWGETGELVVGGIGLGRYLDEEKDRESYRALPALGWNRSYHTGDLVKAEPEGLIFAGRVDDQIKIG
GRRLELGEVDGYLNDIPGVDAAAAAVRTTESGNDVLVGYLSGADPDAIDLQQARKLVAEKMPKGVVPLLCVLDELPMKTS
GKVDRKALPWPLATQQDTGGLPERYAALGELWIEQLGPVSLTSDSNFFELGGGSVAVARLAARIRETHPGAEIGELYQNP
FLGRMSHYLESLVSDSEERPMPKRIPRIGVLFQGFWVLFLYLINALRYVTGVLIVVWLLERFFDAGWVPGISGFPLLIAW
LVLYSLPGKVMITALITRPLTFRMKAGRYRRGGWTHLRLWASQRTLTFMQLENLNGTPFAPMMHRLLGTKVGRNTSLSHS
PSVTGLLTIEKGATVEFEADLEGYWIDGDTLIVDTITIGENVRVGARSIIQPGVRIAPGAEILPGTNVDRDIEGPETWSG
SPMTYQGPAGETWPATTPSNTRETPVMGRLRSGLTYGGGLLVLRILQVAALVPGFMLVFPFVSRLEFYELVFPILIVWVP
VFTILMVFTWLLGVVIVIRILSVFIRPGYFPQRSFTGFAVWLTHTLMQRTLISTYPIYASSFTPLWFRLLGARVGKNVEI
STVETIPHLTWIRSGSFLADHALANSTRMCRGWLHVGTTVIGEGSFVGNSAIVGPDRDVSDGALMAVLSTAPYHPEAGSS
WLGRHPMQITRQRVKGEDSLTYKPPFQRKVLRAGVELCRIIPAMISNWMDLLSVYILTSIYMYYWLGGETQLDSLMFASL
WSWPVLVASGSLAALVALIAKWLLVGRFRERSVPLFSSLVWRGELADVFIESLAIPGFVRMSLGTPMLNLWHRCLGVKIG
RSVWCETWWLPEFDLIRISDLASVNRGTVLQTHLFHDRVMSMEPVVLEDGATLGPNSFVLPGAVIGECTTVRTGSLVQRQ
EALPDNSEWAGNPVRYLGSTSSNAGRAETGQETLVMEGEDQ

Sequences:

>Translated_1321_residues
MSTQDHPKYAVYGVEAPPPECTLIDIVDATVAMYPEVRGLEGTNGTLTYSELRDTIEVEVSRLRSAGVGRGDRVGIRVPS
GTVDLYVAILATLYAGAAYVPVDWDESDSRAQTVWEEADVAVVYGLSLSIDVRRHEPNTDHSRATLDDDAWIIFTSGTTG
KPKGVAITHRSAAALVESERLLYLVDAPLGPQDRVMGGLSVAFDASCEEMWLAWRNGSTLVAAPRDLVRSGEELGQWIVD
EKITAVSTVPTLAAMWDPDSLTAVRLLIFGGEACPLPLIEKLFVPGRELWNTYGPTETTVIVSGQLMTPEPPVRIGRPIV
GWELAVVNEDGIPVNWGETGELVVGGIGLGRYLDEEKDRESYRALPALGWNRSYHTGDLVKAEPEGLIFAGRVDDQIKIG
GRRLELGEVDGYLNDIPGVDAAAAAVRTTESGNDVLVGYLSGADPDAIDLQQARKLVAEKMPKGVVPLLCVLDELPMKTS
GKVDRKALPWPLATQQDTGGLPERYAALGELWIEQLGPVSLTSDSNFFELGGGSVAVARLAARIRETHPGAEIGELYQNP
FLGRMSHYLESLVSDSEERPMPKRIPRIGVLFQGFWVLFLYLINALRYVTGVLIVVWLLERFFDAGWVPGISGFPLLIAW
LVLYSLPGKVMITALITRPLTFRMKAGRYRRGGWTHLRLWASQRTLTFMQLENLNGTPFAPMMHRLLGTKVGRNTSLSHS
PSVTGLLTIEKGATVEFEADLEGYWIDGDTLIVDTITIGENVRVGARSIIQPGVRIAPGAEILPGTNVDRDIEGPETWSG
SPMTYQGPAGETWPATTPSNTRETPVMGRLRSGLTYGGGLLVLRILQVAALVPGFMLVFPFVSRLEFYELVFPILIVWVP
VFTILMVFTWLLGVVIVIRILSVFIRPGYFPQRSFTGFAVWLTHTLMQRTLISTYPIYASSFTPLWFRLLGARVGKNVEI
STVETIPHLTWIRSGSFLADHALANSTRMCRGWLHVGTTVIGEGSFVGNSAIVGPDRDVSDGALMAVLSTAPYHPEAGSS
WLGRHPMQITRQRVKGEDSLTYKPPFQRKVLRAGVELCRIIPAMISNWMDLLSVYILTSIYMYYWLGGETQLDSLMFASL
WSWPVLVASGSLAALVALIAKWLLVGRFRERSVPLFSSLVWRGELADVFIESLAIPGFVRMSLGTPMLNLWHRCLGVKIG
RSVWCETWWLPEFDLIRISDLASVNRGTVLQTHLFHDRVMSMEPVVLEDGATLGPNSFVLPGAVIGECTTVRTGSLVQRQ
EALPDNSEWAGNPVRYLGSTSSNAGRAETGQETLVMEGEDQ
>Mature_1320_residues
STQDHPKYAVYGVEAPPPECTLIDIVDATVAMYPEVRGLEGTNGTLTYSELRDTIEVEVSRLRSAGVGRGDRVGIRVPSG
TVDLYVAILATLYAGAAYVPVDWDESDSRAQTVWEEADVAVVYGLSLSIDVRRHEPNTDHSRATLDDDAWIIFTSGTTGK
PKGVAITHRSAAALVESERLLYLVDAPLGPQDRVMGGLSVAFDASCEEMWLAWRNGSTLVAAPRDLVRSGEELGQWIVDE
KITAVSTVPTLAAMWDPDSLTAVRLLIFGGEACPLPLIEKLFVPGRELWNTYGPTETTVIVSGQLMTPEPPVRIGRPIVG
WELAVVNEDGIPVNWGETGELVVGGIGLGRYLDEEKDRESYRALPALGWNRSYHTGDLVKAEPEGLIFAGRVDDQIKIGG
RRLELGEVDGYLNDIPGVDAAAAAVRTTESGNDVLVGYLSGADPDAIDLQQARKLVAEKMPKGVVPLLCVLDELPMKTSG
KVDRKALPWPLATQQDTGGLPERYAALGELWIEQLGPVSLTSDSNFFELGGGSVAVARLAARIRETHPGAEIGELYQNPF
LGRMSHYLESLVSDSEERPMPKRIPRIGVLFQGFWVLFLYLINALRYVTGVLIVVWLLERFFDAGWVPGISGFPLLIAWL
VLYSLPGKVMITALITRPLTFRMKAGRYRRGGWTHLRLWASQRTLTFMQLENLNGTPFAPMMHRLLGTKVGRNTSLSHSP
SVTGLLTIEKGATVEFEADLEGYWIDGDTLIVDTITIGENVRVGARSIIQPGVRIAPGAEILPGTNVDRDIEGPETWSGS
PMTYQGPAGETWPATTPSNTRETPVMGRLRSGLTYGGGLLVLRILQVAALVPGFMLVFPFVSRLEFYELVFPILIVWVPV
FTILMVFTWLLGVVIVIRILSVFIRPGYFPQRSFTGFAVWLTHTLMQRTLISTYPIYASSFTPLWFRLLGARVGKNVEIS
TVETIPHLTWIRSGSFLADHALANSTRMCRGWLHVGTTVIGEGSFVGNSAIVGPDRDVSDGALMAVLSTAPYHPEAGSSW
LGRHPMQITRQRVKGEDSLTYKPPFQRKVLRAGVELCRIIPAMISNWMDLLSVYILTSIYMYYWLGGETQLDSLMFASLW
SWPVLVASGSLAALVALIAKWLLVGRFRERSVPLFSSLVWRGELADVFIESLAIPGFVRMSLGTPMLNLWHRCLGVKIGR
SVWCETWWLPEFDLIRISDLASVNRGTVLQTHLFHDRVMSMEPVVLEDGATLGPNSFVLPGAVIGECTTVRTGSLVQRQE
ALPDNSEWAGNPVRYLGSTSSNAGRAETGQETLVMEGEDQ

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=465, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI38505220, Length=381, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1786801, Length=583, Percent_Identity=29.3310463121784, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17556356, Length=504, Percent_Identity=26.3888888888889, Blast_Score=110, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32564422, Length=518, Percent_Identity=25.4826254826255, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564420, Length=518, Percent_Identity=25.4826254826255, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=375, Percent_Identity=25.3333333333333, Blast_Score=84, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=474, Percent_Identity=22.9957805907173, Blast_Score=78, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=498, Percent_Identity=23.6947791164659, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648676, Length=549, Percent_Identity=24.408014571949, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24648260, Length=356, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 145155; Mature: 145024

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50075 ACP_DOMAIN ; PS00101 HEXAPEP_TRANSFERASES ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQDHPKYAVYGVEAPPPECTLIDIVDATVAMYPEVRGLEGTNGTLTYSELRDTIEVEV
CCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHH
SRLRSAGVGRGDRVGIRVPSGTVDLYVAILATLYAGAAYVPVDWDESDSRAQTVWEEADV
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCE
AVVYGLSLSIDVRRHEPNTDHSRATLDDDAWIIFTSGTTGKPKGVAITHRSAAALVESER
EEEEEEEEEEEEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCEEEECCHHHHHHCCCC
LLYLVDAPLGPQDRVMGGLSVAFDASCEEMWLAWRNGSTLVAAPRDLVRSGEELGQWIVD
EEEEEECCCCCHHHHHCCEEEEECCCHHHHEEEECCCCEEEECCHHHHHCHHHHHHHHHH
EKITAVSTVPTLAAMWDPDSLTAVRLLIFGGEACPLPLIEKLFVPGRELWNTYGPTETTV
CCHHHHHHHHHHHEECCCCCHHHEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCCCEEE
IVSGQLMTPEPPVRIGRPIVGWELAVVNEDGIPVNWGETGELVVGGIGLGRYLDEEKDRE
EEECEEECCCCCHHHCCCEECEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHCCHHHHH
SYRALPALGWNRSYHTGDLVKAEPEGLIFAGRVDDQIKIGGRRLELGEVDGYLNDIPGVD
HHHHCCCCCCCCCCCCCCCEEECCCCEEEECCCCCEEEECCEEEEECCCCCHHHCCCCCC
AAAAAVRTTESGNDVLVGYLSGADPDAIDLQQARKLVAEKMPKGVVPLLCVLDELPMKTS
HHHHHHEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GKVDRKALPWPLATQQDTGGLPERYAALGELWIEQLGPVSLTSDSNFFELGGGSVAVARL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCHHHHHHH
AARIRETHPGAEIGELYQNPFLGRMSHYLESLVSDSEERPMPKRIPRIGVLFQGFWVLFL
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHH
YLINALRYVTGVLIVVWLLERFFDAGWVPGISGFPLLIAWLVLYSLPGKVMITALITRPL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCE
TFRMKAGRYRRGGWTHLRLWASQRTLTFMQLENLNGTPFAPMMHRLLGTKVGRNTSLSHS
EEEECCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCC
PSVTGLLTIEKGATVEFEADLEGYWIDGDTLIVDTITIGENVRVGARSIIQPGVRIAPGA
CCCEEEEEECCCCEEEEEECCCEEEECCCEEEEEEEEECCCCCCCHHHHHCCCCEECCCC
EILPGTNVDRDIEGPETWSGSPMTYQGPAGETWPATTPSNTRETPVMGRLRSGLTYGGGL
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHH
LVLRILQVAALVPGFMLVFPFVSRLEFYELVFPILIVWVPVFTILMVFTWLLGVVIVIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVFIRPGYFPQRSFTGFAVWLTHTLMQRTLISTYPIYASSFTPLWFRLLGARVGKNVEI
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEE
STVETIPHLTWIRSGSFLADHALANSTRMCRGWLHVGTTVIGEGSFVGNSAIVGPDRDVS
EEHHHCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCC
DGALMAVLSTAPYHPEAGSSWLGRHPMQITRQRVKGEDSLTYKPPFQRKVLRAGVELCRI
CCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHH
IPAMISNWMDLLSVYILTSIYMYYWLGGETQLDSLMFASLWSWPVLVASGSLAALVALIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEECCCHHHHHHHHH
KWLLVGRFRERSVPLFSSLVWRGELADVFIESLAIPGFVRMSLGTPMLNLWHRCLGVKIG
HHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHC
RSVWCETWWLPEFDLIRISDLASVNRGTVLQTHLFHDRVMSMEPVVLEDGATLGPNSFVL
CHHHEEECCCCCCCEEEEHHHHCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCCCCEEC
PGAVIGECTTVRTGSLVQRQEALPDNSEWAGNPVRYLGSTSSNAGRAETGQETLVMEGED
CCHHHCCCCEECCCHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEECCCC
Q
C
>Mature Secondary Structure 
STQDHPKYAVYGVEAPPPECTLIDIVDATVAMYPEVRGLEGTNGTLTYSELRDTIEVEV
CCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHH
SRLRSAGVGRGDRVGIRVPSGTVDLYVAILATLYAGAAYVPVDWDESDSRAQTVWEEADV
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCE
AVVYGLSLSIDVRRHEPNTDHSRATLDDDAWIIFTSGTTGKPKGVAITHRSAAALVESER
EEEEEEEEEEEEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCEEEECCHHHHHHCCCC
LLYLVDAPLGPQDRVMGGLSVAFDASCEEMWLAWRNGSTLVAAPRDLVRSGEELGQWIVD
EEEEEECCCCCHHHHHCCEEEEECCCHHHHEEEECCCCEEEECCHHHHHCHHHHHHHHHH
EKITAVSTVPTLAAMWDPDSLTAVRLLIFGGEACPLPLIEKLFVPGRELWNTYGPTETTV
CCHHHHHHHHHHHEECCCCCHHHEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCCCEEE
IVSGQLMTPEPPVRIGRPIVGWELAVVNEDGIPVNWGETGELVVGGIGLGRYLDEEKDRE
EEECEEECCCCCHHHCCCEECEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHCCHHHHH
SYRALPALGWNRSYHTGDLVKAEPEGLIFAGRVDDQIKIGGRRLELGEVDGYLNDIPGVD
HHHHCCCCCCCCCCCCCCCEEECCCCEEEECCCCCEEEECCEEEEECCCCCHHHCCCCCC
AAAAAVRTTESGNDVLVGYLSGADPDAIDLQQARKLVAEKMPKGVVPLLCVLDELPMKTS
HHHHHHEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GKVDRKALPWPLATQQDTGGLPERYAALGELWIEQLGPVSLTSDSNFFELGGGSVAVARL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCHHHHHHH
AARIRETHPGAEIGELYQNPFLGRMSHYLESLVSDSEERPMPKRIPRIGVLFQGFWVLFL
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHH
YLINALRYVTGVLIVVWLLERFFDAGWVPGISGFPLLIAWLVLYSLPGKVMITALITRPL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCE
TFRMKAGRYRRGGWTHLRLWASQRTLTFMQLENLNGTPFAPMMHRLLGTKVGRNTSLSHS
EEEECCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCC
PSVTGLLTIEKGATVEFEADLEGYWIDGDTLIVDTITIGENVRVGARSIIQPGVRIAPGA
CCCEEEEEECCCCEEEEEECCCEEEECCCEEEEEEEEECCCCCCCHHHHHCCCCEECCCC
EILPGTNVDRDIEGPETWSGSPMTYQGPAGETWPATTPSNTRETPVMGRLRSGLTYGGGL
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHH
LVLRILQVAALVPGFMLVFPFVSRLEFYELVFPILIVWVPVFTILMVFTWLLGVVIVIRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSVFIRPGYFPQRSFTGFAVWLTHTLMQRTLISTYPIYASSFTPLWFRLLGARVGKNVEI
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEE
STVETIPHLTWIRSGSFLADHALANSTRMCRGWLHVGTTVIGEGSFVGNSAIVGPDRDVS
EEHHHCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCC
DGALMAVLSTAPYHPEAGSSWLGRHPMQITRQRVKGEDSLTYKPPFQRKVLRAGVELCRI
CCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHH
IPAMISNWMDLLSVYILTSIYMYYWLGGETQLDSLMFASLWSWPVLVASGSLAALVALIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEECCCHHHHHHHHH
KWLLVGRFRERSVPLFSSLVWRGELADVFIESLAIPGFVRMSLGTPMLNLWHRCLGVKIG
HHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHC
RSVWCETWWLPEFDLIRISDLASVNRGTVLQTHLFHDRVMSMEPVVLEDGATLGPNSFVL
CHHHEEECCCCCCCEEEEHHHHCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCCCCEEC
PGAVIGECTTVRTGSLVQRQEALPDNSEWAGNPVRYLGSTSSNAGRAETGQETLVMEGED
CCHHHCCCCEECCCHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEECCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]