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The map label for this gene is iolC [H]

Identifier: 145294281

GI number: 145294281

Start: 256033

End: 257013

Strand: Direct

Name: iolC [H]

Synonym: cgR_0237

Alternate gene names: 145294281

Gene position: 256033-257013 (Clockwise)

Preceding gene: 145294279

Following gene: 145294282

Centisome position: 7.73

GC content: 55.76

Gene sequence:

>981_bases
ATGAGTGAAGGGTTGCATCGCCACATGACTAACTTGACGAGCACTCACGAAGTCCTAGCTATCGGCCGCTTGGGCGTAGA
TATTTACCCACTTCAAAGTGGAGTAGGACTGGCCGATGTTCAATCTTTCGGCAAGTACCTCGGCGGAAGCGCAGCGAATG
TTTCTGTTGCAGCCGCTCGCCATGGACACAATTCCGCACTGCTGTCCCGTGTGGGAAATGATCCTTTCGGCGAGTACCTG
CTTGCTGAGCTGGAGCGTTTGGGCGTGGACAACCAGTACGTTGCCACCGATCAGACTTTTAAGACCCCAGTGACCTTCTG
TGAAATTTTCCCACCAGATGATTTCCCACTGTACTTCTACCGCGAACCAAAGGCTCCGGATCTCAATATTGAATCCGCAG
ACGTCAGCCTGGACGATGTGCGCGAAGCCGATATTTTATGGTTCACACTCACTGGTTTCAGTGAAGAGCCAAGCCGCGGC
ACACACCGCGAGATCTTGACTACTCGTGCGAACCGTCGCCACACCATCTTTGATCTGGACTACCGACCAATGTTCTGGGA
ATCCCCAGAAGAGGCCACCAAGCAGGCGGAATGGGCGTTGCAGCATTCCACGGTGGCGGTTGGCAACAAGGAAGAATGCG
AAATCGCAGTGGGCGAGACCGAACCAGAGCGCGCGGGCCGAGCACTGTTGGAACGCGGTGTGGAGTTGGCCATCGTCAAG
CAGGGACCTAAGGGTGTCATGGCGATGACCAAGGACGAAACCGTAGAAGTTCCTCCGTTCTTCGTCGATGTCATCAACGG
TCTTGGTGCCGGCGATGCATTCGGCGGCGCGCTGTGCCACGGTCTGCTCTCTGAATGGCCGTTGGAAAAGGTTCTCCGTT
TTGCCAACACCGCGGGTGCGCTTGTGGCGTCCCGTCTTGAATGCTCCACCGCAATGCCTACTACCGATGAGGTGGAAGCC
TCCCTCAACCAGAAAGTCTGA

Upstream 100 bases:

>100_bases
GTGAATCGTTTTAGAAAATTTTCGGAAATGTATTGCTTTGTCAGGACAATGTGTTATTGTCATGACATGCGATCGTGAGG
GTCGCCACATTCCATCGAAA

Downstream 100 bases:

>100_bases
TATGACTCCTCCGATTATCTCCCCAGAGAGCTTTGAAGCCCTAAGGCGGATGCGTGCGGCTGAACCCACGATGGTGGCGG
AACGTTTCAAGCAGCGCCGT

Product: sugar kinase, ribokinase family

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSALLSRVGNDPFGEYL
LAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRG
THREILTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRALLERGVELAIVK
QGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLECSTAMPTTDEVEA
SLNQKV

Sequences:

>Translated_326_residues
MSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSALLSRVGNDPFGEYL
LAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRG
THREILTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRALLERGVELAIVK
QGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLECSTAMPTTDEVEA
SLNQKV
>Mature_325_residues
SEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSALLSRVGNDPFGEYLL
AELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRGT
HREILTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRALLERGVELAIVKQ
GPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALVASRLECSTAMPTTDEVEAS
LNQKV

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=324, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790193, Length=284, Percent_Identity=26.4084507042254, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 35695; Mature: 35564

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAAR
CCCCHHHHHHHCCCHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEC
HGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFY
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCEEEE
REPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRGTHREILTTRANRRHTIFDLD
ECCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEC
YRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRALLERGVELAIVK
CCCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEE
QGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGA
CCCCCCEEECCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVASRLECSTAMPTTDEVEASLNQKV
HHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SEGLHRHMTNLTSTHEVLAIGRLGVDIYPLQSGVGLADVQSFGKYLGGSAANVSVAAAR
CCCHHHHHHHCCCHHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEC
HGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFY
CCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCCCCEEEE
REPKAPDLNIESADVSLDDVREADILWFTLTGFSEEPSRGTHREILTTRANRRHTIFDLD
ECCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEEC
YRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRALLERGVELAIVK
CCCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEE
QGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGA
CCCCCCEEECCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVASRLECSTAMPTTDEVEASLNQKV
HHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA