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The map label for this gene is rhtC [H]

Identifier: 145294269

GI number: 145294269

Start: 242391

End: 243071

Strand: Direct

Name: rhtC [H]

Synonym: cgR_0225

Alternate gene names: 145294269

Gene position: 242391-243071 (Clockwise)

Preceding gene: 145294268

Following gene: 145294270

Centisome position: 7.31

GC content: 54.19

Gene sequence:

>681_bases
ATGACAACAGCACAGTTTCTAGCGCTTTTTCTGGTGTGGATCGCAGCAATTGCATCCCCCGGGCCAGACCTTTTCCAGAT
CATCAGGCTAGGTGCCAAAAACCGCCGTGATGGCGTACTGACTGCCGTAGGCATCATGGTCGGAAACTCCATCTGGATCA
TAGCCAGCCTCCTCGGGCTCTCGGCACTGATCTCCACGCATCCAGCAATTTTGAACCTGTTGCAGCTCGTCGGCGGCGGT
TATTTGACCTGGATGGGCATCGGGGCAGTGAGGTCATGGTGGACGAAACGCTCCACACAGCAAGCTGCAGCGGATTCTCA
AGCTGTAGAGAATACGTTGGTGACAGCCACGGCTGCATCTGTCGGAGTGTGGCCAGCTATTCGATCTGGCATTGCTACCA
ACTTGTCCAACCCCAAAGCTGTGCTGTTTTTTGGTTCCGTTTTCGCCCAATTTGTTAGACCTGACATGGGAATCGGGTGG
AGTATTTTCATTGGAGTCTTCCTCACCCTCACTGGCCTGCTGTGGTTTGTGGGATTCGCCGTCTTGGTCCGCAAACTAGC
CGTTGGCATCACCCGAAATGGAGCCATCATCGACCTGCTAACGGGGGTGATTTTCATCGGGCTGGGAATGTTCATGATCT
TCGAGGGGGTTGTAGGAATCGGTGGCAGGGTAGTGGGTTAG

Upstream 100 bases:

>100_bases
TAAAGCTTTAGGTTTTACCCATATCGGACTGACCTCTTTGAGCATCCTCCAGCAGGCCATTGGGGTCACAGAGCTGAAAG
CTGCCTAAGATATAACTCCG

Downstream 100 bases:

>100_bases
CCCCGCCCCCAGGACGTCACTAGACTTAGGCACCATGCAACCTGAAGAAGTGCACATCAAGGACGAGACCATCAAGTTAG
GTCAGTTCATCAAATTGGCC

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTTAQFLALFLVWIAAIASPGPDLFQIIRLGAKNRRDGVLTAVGIMVGNSIWIIASLLGLSALISTHPAILNLLQLVGGG
YLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAASVGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGW
SIFIGVFLTLTGLLWFVGFAVLVRKLAVGITRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG

Sequences:

>Translated_226_residues
MTTAQFLALFLVWIAAIASPGPDLFQIIRLGAKNRRDGVLTAVGIMVGNSIWIIASLLGLSALISTHPAILNLLQLVGGG
YLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAASVGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGW
SIFIGVFLTLTGLLWFVGFAVLVRKLAVGITRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG
>Mature_225_residues
TTAQFLALFLVWIAAIASPGPDLFQIIRLGAKNRRDGVLTAVGIMVGNSIWIIASLLGLSALISTHPAILNLLQLVGGGY
LTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAASVGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGWS
IFIGVFLTLTGLLWFVGFAVLVRKLAVGITRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=217, Percent_Identity=34.5622119815668, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786522, Length=132, Percent_Identity=34.0909090909091, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23861; Mature: 23729

Theoretical pI: Translated: 11.73; Mature: 11.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQFLALFLVWIAAIASPGPDLFQIIRLGAKNRRDGVLTAVGIMVGNSIWIIASLLGL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
SALISTHPAILNLLQLVGGGYLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAAS
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGWSIFIGVFLTLTGLLWFVGFA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVRKLAVGITRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure 
TTAQFLALFLVWIAAIASPGPDLFQIIRLGAKNRRDGVLTAVGIMVGNSIWIIASLLGL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
SALISTHPAILNLLQLVGGGYLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAAS
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGWSIFIGVFLTLTGLLWFVGFA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVRKLAVGITRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]