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The map label for this gene is qoxB [H]

Identifier: 138897019

GI number: 138897019

Start: 3496298

End: 3498244

Strand: Reverse

Name: qoxB [H]

Synonym: GTNG_3390

Alternate gene names: 138897019

Gene position: 3498244-3496298 (Counterclockwise)

Preceding gene: 138897020

Following gene: 138897018

Centisome position: 98.53

GC content: 48.79

Gene sequence:

>1947_bases
ATGAAATGGAGCGAGTTTTTCGTCACGGGTGAGCCGTTGATTTATGCGGCTGATGTCGCGATCGTCTTAACGATGGTCGG
CATTGTGTTCGTATTGACGTATTTTAAAAAGTGGAAATGGATTTGGAATGAATGGCTTACGACTGTCGACCATAAAAAAA
TTGGCGTCATGTACATTATTTGCGCGGTGCTCATGCTCTTCCGCGGCGGCGTCGATGCCCTTTTAATGCGGGCACAGTTG
ACAGCTCCTAATATGAATTTTCTTGATGCCCAGCATTATAATGAAATTTTCACTACGCACGGGACGATTATGATTTTGTT
TATGGCGATGCCGTTTATTATCGGTTTGATGAACATTGTCGTTCCGCTGCAAATCGGGGCGCGCGATGTCGCGTTTCCAT
ACTTGAATGCGTTAAGTTTTTGGCTCTTTTTCTTCGGTGCAATGTTGTTTAACATTTCGTTTGTCATTGGCGGTTCGCCG
GATGCTGGTTGGACGGCGTACTTTCCGCTCGCTGGCAATGAGTTCAGCCCTGGCGTCGGCAACAACTATTACGCTGTTTC
CTTGCAAATTTCCGGGATCGGAACGTTAATGACCGGAATCAACTTCCTTGTGACGATTTTGAAAATGCGCGCGCCAGGCA
TGACGTTGATGCGCATGCCAATGTTTACGTGGACGATTCTCATTACGTGCGTTTTGATTGTGTTCGCTTTCCCAGTGTTG
ACAGTTGCGTTGGCGTTAATGACGTTCGACCGCTTATTTGATACACAGTTTTTCACGATGGCGAATGGCGGTATGTCGAT
GCTGTGGGCGAACTTGTTCTGGATTTGGGGACATCCGGAAGTATATATTGTGATTTTGCCAGCGTTCGGCATTTTCTCGG
AAATCGTCAGTACGTTTGCGCAGAAACGGCTGTTTGGCTATAAAGCGATGGTTTACTCGATCGTCGGTATCGCCTTTTTA
AGCTTTATTGTTTGGGTGCACCATTTCTTTACGATGGGCGCCGGACCAGAGGTTAACTCGGTATTCTCGATTACGACGAT
GGCTGTTGCCATCCCAACCGGGGTGAAAATTTTCAACTGGTTGTTTACGCTCCGGAAAGGGAAGATCCGTTTTACGACGG
CGATGCTTTGGTCGCTGGCATTCATTCCGAACTTTGTCATCGGCGGTGTGACGGGCGTTATGTTGGCGATGGCAGCGGCT
GATTACCAATATCATAACAGCTATTTCTTGATTGCCCACTTCCATTATGTGTTAATCGCGGGTGTGGTGTTTGCCTGCTT
TGCCGGCTTGCATTACTGGTATCCGAAGATGTTCGGCCATATGTTAAACGAGCGGCTCGGCAAATGGACGTTTTGGCTAT
TTATGATCGGCTTTAACGTCTGTTTCTTCCCGATGTATTTCCTCGGACTTATGGGAATGACGCGCCGCATGTACACATAT
TCGGACGGTCTCGGCTGGACGCCGCTCAACGTCGTTGCGACCGTTGGGGCGGTGCTGATGGGAATCGGATTTATTGTACT
TTGCTATAACATTTATTACAGCGCTCGCTATGGCGAACGTGACATGACCGGCGACCCGTGGAATGGACGGACGCTTGAGT
GGGCGACTGCGTCGCCACCGGTGCACTACAATTTCCCGGTCACTCCGATTGTTGACGATTTGGATGCGTACTGGGTAATG
AAGAAAAAACAAGGCGGTTTCCAAGTGAAAGAGGAGGAATTGAAGCCGATCCATATGCCAAGCAATTCGGGGCGTCCGTT
TTGGATCTCGGTCGCATTCTTTGTCGCAGGGTTTGGTCTTGTGTTCAAATGGTTTGCATTAGCGATTGCCGGTGCGTTGT
TCATTGTGCTCGGGCTCATTCTCCGCTCGTTTGAAAATGATGACGGCTATCATATTGGCGTCGATGAAATTAAACGGACT
GAGCGAGCGGCGCGAAAGGGGGCGTGA

Upstream 100 bases:

>100_bases
ATCATGTCGAGAGGAAATCAGCAGGTAACCATGGCAACCCAGACCATGACATGGCGAAAGACAGTCATCATCACGGAGAA
TAAGAAGGGGGGAACGGGCG

Downstream 100 bases:

>100_bases
CGAATGGGAGAAGCAGTACATCGTTATGATGAAACGATGCCGCTTGAGTATCGGACAGAGGAAAATCGGCTCAACATTTT
AGGATTTTGGATTTTTTTAG

Product: quinol oxidase subunit I

Products: Ubiquinone-8; H2O. [C]

Alternate protein names: Oxidase aa(3)-600 subunit 1; Quinol oxidase aa3-600, subunit qoxB; Quinol oxidase polypeptide I [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MKWSEFFVTGEPLIYAADVAIVLTMVGIVFVLTYFKKWKWIWNEWLTTVDHKKIGVMYIICAVLMLFRGGVDALLMRAQL
TAPNMNFLDAQHYNEIFTTHGTIMILFMAMPFIIGLMNIVVPLQIGARDVAFPYLNALSFWLFFFGAMLFNISFVIGGSP
DAGWTAYFPLAGNEFSPGVGNNYYAVSLQISGIGTLMTGINFLVTILKMRAPGMTLMRMPMFTWTILITCVLIVFAFPVL
TVALALMTFDRLFDTQFFTMANGGMSMLWANLFWIWGHPEVYIVILPAFGIFSEIVSTFAQKRLFGYKAMVYSIVGIAFL
SFIVWVHHFFTMGAGPEVNSVFSITTMAVAIPTGVKIFNWLFTLRKGKIRFTTAMLWSLAFIPNFVIGGVTGVMLAMAAA
DYQYHNSYFLIAHFHYVLIAGVVFACFAGLHYWYPKMFGHMLNERLGKWTFWLFMIGFNVCFFPMYFLGLMGMTRRMYTY
SDGLGWTPLNVVATVGAVLMGIGFIVLCYNIYYSARYGERDMTGDPWNGRTLEWATASPPVHYNFPVTPIVDDLDAYWVM
KKKQGGFQVKEEELKPIHMPSNSGRPFWISVAFFVAGFGLVFKWFALAIAGALFIVLGLILRSFENDDGYHIGVDEIKRT
ERAARKGA

Sequences:

>Translated_648_residues
MKWSEFFVTGEPLIYAADVAIVLTMVGIVFVLTYFKKWKWIWNEWLTTVDHKKIGVMYIICAVLMLFRGGVDALLMRAQL
TAPNMNFLDAQHYNEIFTTHGTIMILFMAMPFIIGLMNIVVPLQIGARDVAFPYLNALSFWLFFFGAMLFNISFVIGGSP
DAGWTAYFPLAGNEFSPGVGNNYYAVSLQISGIGTLMTGINFLVTILKMRAPGMTLMRMPMFTWTILITCVLIVFAFPVL
TVALALMTFDRLFDTQFFTMANGGMSMLWANLFWIWGHPEVYIVILPAFGIFSEIVSTFAQKRLFGYKAMVYSIVGIAFL
SFIVWVHHFFTMGAGPEVNSVFSITTMAVAIPTGVKIFNWLFTLRKGKIRFTTAMLWSLAFIPNFVIGGVTGVMLAMAAA
DYQYHNSYFLIAHFHYVLIAGVVFACFAGLHYWYPKMFGHMLNERLGKWTFWLFMIGFNVCFFPMYFLGLMGMTRRMYTY
SDGLGWTPLNVVATVGAVLMGIGFIVLCYNIYYSARYGERDMTGDPWNGRTLEWATASPPVHYNFPVTPIVDDLDAYWVM
KKKQGGFQVKEEELKPIHMPSNSGRPFWISVAFFVAGFGLVFKWFALAIAGALFIVLGLILRSFENDDGYHIGVDEIKRT
ERAARKGA
>Mature_648_residues
MKWSEFFVTGEPLIYAADVAIVLTMVGIVFVLTYFKKWKWIWNEWLTTVDHKKIGVMYIICAVLMLFRGGVDALLMRAQL
TAPNMNFLDAQHYNEIFTTHGTIMILFMAMPFIIGLMNIVVPLQIGARDVAFPYLNALSFWLFFFGAMLFNISFVIGGSP
DAGWTAYFPLAGNEFSPGVGNNYYAVSLQISGIGTLMTGINFLVTILKMRAPGMTLMRMPMFTWTILITCVLIVFAFPVL
TVALALMTFDRLFDTQFFTMANGGMSMLWANLFWIWGHPEVYIVILPAFGIFSEIVSTFAQKRLFGYKAMVYSIVGIAFL
SFIVWVHHFFTMGAGPEVNSVFSITTMAVAIPTGVKIFNWLFTLRKGKIRFTTAMLWSLAFIPNFVIGGVTGVMLAMAAA
DYQYHNSYFLIAHFHYVLIAGVVFACFAGLHYWYPKMFGHMLNERLGKWTFWLFMIGFNVCFFPMYFLGLMGMTRRMYTY
SDGLGWTPLNVVATVGAVLMGIGFIVLCYNIYYSARYGERDMTGDPWNGRTLEWATASPPVHYNFPVTPIVDDLDAYWVM
KKKQGGFQVKEEELKPIHMPSNSGRPFWISVAFFVAGFGLVFKWFALAIAGALFIVLGLILRSFENDDGYHIGVDEIKRT
ERAARKGA

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=507, Percent_Identity=40.6311637080868, Blast_Score=360, Evalue=3e-99,
Organism=Escherichia coli, GI1786634, Length=637, Percent_Identity=54.6310832025118, Blast_Score=684, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=474, Percent_Identity=40.5063291139241, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=38.8198757763975, Blast_Score=240, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=245, Percent_Identity=33.0612244897959, Blast_Score=133, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.10.3.- [C]

Molecular weight: Translated: 73361; Mature: 73361

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEFFVTGEPLIYAADVAIVLTMVGIVFVLTYFKKWKWIWNEWLTTVDHKKIGVMYII
CCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CAVLMLFRGGVDALLMRAQLTAPNMNFLDAQHYNEIFTTHGTIMILFMAMPFIIGLMNIV
HHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VPLQIGARDVAFPYLNALSFWLFFFGAMLFNISFVIGGSPDAGWTAYFPLAGNEFSPGVG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCCCC
NNYYAVSLQISGIGTLMTGINFLVTILKMRAPGMTLMRMPMFTWTILITCVLIVFAFPVL
CCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVALALMTFDRLFDTQFFTMANGGMSMLWANLFWIWGHPEVYIVILPAFGIFSEIVSTFA
HHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHEEEECCCEEEEEEECHHHHHHHHHHHHH
QKRLFGYKAMVYSIVGIAFLSFIVWVHHFFTMGAGPEVNSVFSITTMAVAIPTGVKIFNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
LFTLRKGKIRFTTAMLWSLAFIPNFVIGGVTGVMLAMAAADYQYHNSYFLIAHFHYVLIA
HHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEHHHHHHHHHH
GVVFACFAGLHYWYPKMFGHMLNERLGKWTFWLFMIGFNVCFFPMYFLGLMGMTRRMYTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
SDGLGWTPLNVVATVGAVLMGIGFIVLCYNIYYSARYGERDMTGDPWNGRTLEWATASPP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCC
VHYNFPVTPIVDDLDAYWVMKKKQGGFQVKEEELKPIHMPSNSGRPFWISVAFFVAGFGL
EEECCCCCCHHHCCCHHEEEEECCCCCCCCHHCCCCEECCCCCCCCEEEEHHHHHHHHHH
VFKWFALAIAGALFIVLGLILRSFENDDGYHIGVDEIKRTERAARKGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKWSEFFVTGEPLIYAADVAIVLTMVGIVFVLTYFKKWKWIWNEWLTTVDHKKIGVMYII
CCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CAVLMLFRGGVDALLMRAQLTAPNMNFLDAQHYNEIFTTHGTIMILFMAMPFIIGLMNIV
HHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VPLQIGARDVAFPYLNALSFWLFFFGAMLFNISFVIGGSPDAGWTAYFPLAGNEFSPGVG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCCCCCC
NNYYAVSLQISGIGTLMTGINFLVTILKMRAPGMTLMRMPMFTWTILITCVLIVFAFPVL
CCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVALALMTFDRLFDTQFFTMANGGMSMLWANLFWIWGHPEVYIVILPAFGIFSEIVSTFA
HHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHEEEECCCEEEEEEECHHHHHHHHHHHHH
QKRLFGYKAMVYSIVGIAFLSFIVWVHHFFTMGAGPEVNSVFSITTMAVAIPTGVKIFNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
LFTLRKGKIRFTTAMLWSLAFIPNFVIGGVTGVMLAMAAADYQYHNSYFLIAHFHYVLIA
HHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEHHHHHHHHHH
GVVFACFAGLHYWYPKMFGHMLNERLGKWTFWLFMIGFNVCFFPMYFLGLMGMTRRMYTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
SDGLGWTPLNVVATVGAVLMGIGFIVLCYNIYYSARYGERDMTGDPWNGRTLEWATASPP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCC
VHYNFPVTPIVDDLDAYWVMKKKQGGFQVKEEELKPIHMPSNSGRPFWISVAFFVAGFGL
EEECCCCCCHHHCCCHHEEEEECCCCCCCCHHCCCCEECCCCCCCCEEEEHHHHHHHHHH
VFKWFALAIAGALFIVLGLILRSFENDDGYHIGVDEIKRTERAARKGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ubiquinol-8; O(2) [C]

Specific reaction: Ubiquinol-8 + O(2) = Ubiquinone-8 + H2O. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7575098 [H]