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The map label for this gene is fba [H]

Identifier: 138896962

GI number: 138896962

Start: 3436819

End: 3437682

Strand: Reverse

Name: fba [H]

Synonym: GTNG_3331

Alternate gene names: 138896962

Gene position: 3437682-3436819 (Counterclockwise)

Preceding gene: 138896963

Following gene: 138896961

Centisome position: 96.83

GC content: 53.01

Gene sequence:

>864_bases
ATGCCGTTAGTATCGATGAAAGAGATGCTCAACGAGGCGCTGCGCGGCAAATACGCGGTCGGCCAATTTAACATTAACAA
CTTAGAGTGGACGCAAGCCATTTTAGCGGCGGCTGAAGAGGAAAAATCGCCGGTTATTCTCGGCGTTTCCGAAGGGGCAG
CTCGCTATATGGGTGGCTTTAAAACGGTCGTCAACATGGTGAAAGGCTTAATGGAAGACATGAACATTACGGTTCCAGTT
GCCATTCACCTTGACCATGGTTCGAGCTTTGAAAAATGTAAAGCGGCAATCGACGCCGGATTCACCTCGGTCATGATTGA
CGCCTCCCACCACCCGTTTGAAGAGAACGTCCGCATCACCTCGCAAGTCGTTGAATACGCCCATGCGCGCGGCGTTTCTG
TTGAGGCCGAGCTTGGCATCGTCGGCGGGCAAGAGGACGATGTCATCGGTGAAGGTGTCATTTACGCTGATCCGAAAGAA
TGTGAAGAGCTTGTCAAGCGGACAGGCATCGACTGCCTTGCTCCGGCGCTCGGTTCGGTGCATGGCCCTTACAAAGGGGA
GCCAAAACTCGGATTTGCGGAAATGGAACAAATCCGCGACTTAACCGGCATTCCGCTTGTGCTTCACGGCGGCACCGGCA
TCCCAACTGAGCAAATCCAGCGCGCGATTTCCCTTGGCACATCGAAAATCAACGTCAATACGGAAAACCAAATCGCCTTT
ACGAAAGTCGTTCGCGAGTTGCTTGCGAAAGATGCAAACGTTTATGACCCGCGCAAAATTATCGGCCCAGGCCGCGATGC
GATCAAAGCGACGGTCATCGGCAAAATGCGCGAGTTCGGTTCGTCCGGAAAAGCGGCACAATAA

Upstream 100 bases:

>100_bases
TGACAAGTTGGTATGCTTATAACGTAGATGTATTTTGCGCCTGTGGGCCTACGTTCCGCCATGGCGACAAAGACGACGAT
CAGCTAAGGAGGATGTAACC

Downstream 100 bases:

>100_bases
CGCGAAAACGGCAAGATCGGCTCAGCAGGCGGCTTTCAGCCGCCGCCCGGGCTTGCCTGCTTGCGCCCAAATCATGGCAA
GGAGGGTCACTTATGAAATT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPLVSMKEMLNEALRGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARYMGGFKTVVNMVKGLMEDMNITVPV
AIHLDHGSSFEKCKAAIDAGFTSVMIDASHHPFEENVRITSQVVEYAHARGVSVEAELGIVGGQEDDVIGEGVIYADPKE
CEELVKRTGIDCLAPALGSVHGPYKGEPKLGFAEMEQIRDLTGIPLVLHGGTGIPTEQIQRAISLGTSKINVNTENQIAF
TKVVRELLAKDANVYDPRKIIGPGRDAIKATVIGKMREFGSSGKAAQ

Sequences:

>Translated_287_residues
MPLVSMKEMLNEALRGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARYMGGFKTVVNMVKGLMEDMNITVPV
AIHLDHGSSFEKCKAAIDAGFTSVMIDASHHPFEENVRITSQVVEYAHARGVSVEAELGIVGGQEDDVIGEGVIYADPKE
CEELVKRTGIDCLAPALGSVHGPYKGEPKLGFAEMEQIRDLTGIPLVLHGGTGIPTEQIQRAISLGTSKINVNTENQIAF
TKVVRELLAKDANVYDPRKIIGPGRDAIKATVIGKMREFGSSGKAAQ
>Mature_286_residues
PLVSMKEMLNEALRGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARYMGGFKTVVNMVKGLMEDMNITVPVA
IHLDHGSSFEKCKAAIDAGFTSVMIDASHHPFEENVRITSQVVEYAHARGVSVEAELGIVGGQEDDVIGEGVIYADPKEC
EELVKRTGIDCLAPALGSVHGPYKGEPKLGFAEMEQIRDLTGIPLVLHGGTGIPTEQIQRAISLGTSKINVNTENQIAFT
KVVRELLAKDANVYDPRKIIGPGRDAIKATVIGKMREFGSSGKAAQ

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=287, Percent_Identity=40.418118466899, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=39.8601398601399, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1788072, Length=287, Percent_Identity=39.0243902439024, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1789293, Length=333, Percent_Identity=26.4264264264264, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322790, Length=336, Percent_Identity=25.297619047619, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30845; Mature: 30714

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMKEMLNEALRGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARYMGGF
CCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
KTVVNMVKGLMEDMNITVPVAIHLDHGSSFEKCKAAIDAGFTSVMIDASHHPFEENVRIT
HHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHCHHHH
SQVVEYAHARGVSVEAELGIVGGQEDDVIGEGVIYADPKECEELVKRTGIDCLAPALGSV
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCCCHHHHHHHHCC
HGPYKGEPKLGFAEMEQIRDLTGIPLVLHGGTGIPTEQIQRAISLGTSKINVNTENQIAF
CCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHH
TKVVRELLAKDANVYDPRKIIGPGRDAIKATVIGKMREFGSSGKAAQ
HHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PLVSMKEMLNEALRGKYAVGQFNINNLEWTQAILAAAEEEKSPVILGVSEGAARYMGGF
CCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
KTVVNMVKGLMEDMNITVPVAIHLDHGSSFEKCKAAIDAGFTSVMIDASHHPFEENVRIT
HHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCHHCHHHH
SQVVEYAHARGVSVEAELGIVGGQEDDVIGEGVIYADPKECEELVKRTGIDCLAPALGSV
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCCCHHHHHHHHCC
HGPYKGEPKLGFAEMEQIRDLTGIPLVLHGGTGIPTEQIQRAISLGTSKINVNTENQIAF
CCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHH
TKVVRELLAKDANVYDPRKIIGPGRDAIKATVIGKMREFGSSGKAAQ
HHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA