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The map label for this gene is murA2 [H]

Identifier: 138896960

GI number: 138896960

Start: 3434668

End: 3435954

Strand: Reverse

Name: murA2 [H]

Synonym: GTNG_3329

Alternate gene names: 138896960

Gene position: 3435954-3434668 (Counterclockwise)

Preceding gene: 138896961

Following gene: 138896959

Centisome position: 96.78

GC content: 54.23

Gene sequence:

>1287_bases
ATGGATAAAATAAAAATTATCGGCGGGGATCGGCTGCAGGGGACGATTAAAGTGAGCGGCGCGAAAAACAGCGCTGTCGC
CTTGATTCCTGCGGCGATTTTAGCCGATTCGCCGGTGACGATCGAAGGGTTGCCGGACATTTCCGACGTGCGCATTTTGG
GAAGCTTGATCGAAGAGATCGGCGGTTCGTTTTGGTTTGACGGCAAAAAGGCGATCATCGATCCGACGAACATGGTTTCT
ATGCCGCTTCCAAACGGAAAAGTAAAAAAACTGCGCGCTTCGTACTATTTGATGGGAGCGATGCTTGGCCGGTTCAAAAA
AGCGGTCGTCGGCCTGCCGGGCGGCTGTCATCTCGGACCGCGCCCGATCGACCAGCACATTAAAGGATTTGAGGCGCTCG
GTGCAACGGTAACGAACGAGCAGGGCGCCATTTACTTGCGCGCTGAGGAGCTCCGCGGGGCCCGCATTTTTTTGGACGTC
GTCAGCGTCGGTGCGACGATCAACATTATGCTGGCGGCGGTGCGCGCCAAAGGGCGGACGATTATCGAAAACGCCGCGAA
AGAGCCGGAAATCATTGATGTGGCAACATTGCTTTCGAATATGGGCGCAAAAATTAAAGGCGCGGGCACCGATGTCATCC
GTATCGACGGCGTCGAAAAATTATCGGGCTGCCGCCATGCCATCATCCCAGATCGGATTGAAGCCGGTACGTATATGATT
GCCGCCGCAGCGACCGGCAACGAAGTTGTCATTGACAACGTTATTCCGCAGCACGTCGAATCACTGACGGCGAAATTGCG
CGAGATGGGCGTGCACGTCGAGACGGGTGCGGATCAAATTTGGATCTGCGGCTCCGATGTTTTGAAAGCGGTTGACGTCA
AAACGCTCGTCTACCCGGGGTTCCCGACCGATTTGCAGCAGCCGTTAACCGCCTTGTTGACGAAAGCAGACGGCACGAGT
GTCGTCACGGATACGATTTACAGCGCACGCTTCAAACATATCGATGAATTGCGGCGCATGAACGCGAACGTGAAAGTCGA
AGGTCGCTCGGCCATTATCACTGGTCCGGTCAATTTGCAAGGCGCAAAAGTAAAAGCGAGCGACTTGCGCGCTGGGGCGG
CGCTCGTTATCGCCGGGCTCATGGCAGAAGGAGTGACCGAAATCACTGGCGTTGAGCATATCGATCGTGGCTACAGTGGG
TTAGTGGAAAAGCTGTCTAAGATCGGCGCCACCATTTGGCGTGAAAAAATGACCGATGAAGAAATTGAACAAGTAAAAAA
TGCGTAA

Upstream 100 bases:

>100_bases
GGCTGACCTTGCCGCGTTCGGGCTGGGGAATTCAGCCCGCCTGACCACTTTCTCGTCCCTAGGGGTGAAGCCAACTTCCG
AGCAAAGAAGGGAGACGACG

Downstream 100 bases:

>100_bases
CGTCAAGTGCAAAGGGGAAGGGGAGAACAGCAATGGAACGAAGCTTGTCAATGGAACTCGTGCGCGTCACTGAAGCGGCC
GCGCTTGCGGCGGCTCGCTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MDKIKIIGGDRLQGTIKVSGAKNSAVALIPAAILADSPVTIEGLPDISDVRILGSLIEEIGGSFWFDGKKAIIDPTNMVS
MPLPNGKVKKLRASYYLMGAMLGRFKKAVVGLPGGCHLGPRPIDQHIKGFEALGATVTNEQGAIYLRAEELRGARIFLDV
VSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLSNMGAKIKGAGTDVIRIDGVEKLSGCRHAIIPDRIEAGTYMI
AAAATGNEVVIDNVIPQHVESLTAKLREMGVHVETGADQIWICGSDVLKAVDVKTLVYPGFPTDLQQPLTALLTKADGTS
VVTDTIYSARFKHIDELRRMNANVKVEGRSAIITGPVNLQGAKVKASDLRAGAALVIAGLMAEGVTEITGVEHIDRGYSG
LVEKLSKIGATIWREKMTDEEIEQVKNA

Sequences:

>Translated_428_residues
MDKIKIIGGDRLQGTIKVSGAKNSAVALIPAAILADSPVTIEGLPDISDVRILGSLIEEIGGSFWFDGKKAIIDPTNMVS
MPLPNGKVKKLRASYYLMGAMLGRFKKAVVGLPGGCHLGPRPIDQHIKGFEALGATVTNEQGAIYLRAEELRGARIFLDV
VSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLSNMGAKIKGAGTDVIRIDGVEKLSGCRHAIIPDRIEAGTYMI
AAAATGNEVVIDNVIPQHVESLTAKLREMGVHVETGADQIWICGSDVLKAVDVKTLVYPGFPTDLQQPLTALLTKADGTS
VVTDTIYSARFKHIDELRRMNANVKVEGRSAIITGPVNLQGAKVKASDLRAGAALVIAGLMAEGVTEITGVEHIDRGYSG
LVEKLSKIGATIWREKMTDEEIEQVKNA
>Mature_428_residues
MDKIKIIGGDRLQGTIKVSGAKNSAVALIPAAILADSPVTIEGLPDISDVRILGSLIEEIGGSFWFDGKKAIIDPTNMVS
MPLPNGKVKKLRASYYLMGAMLGRFKKAVVGLPGGCHLGPRPIDQHIKGFEALGATVTNEQGAIYLRAEELRGARIFLDV
VSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLSNMGAKIKGAGTDVIRIDGVEKLSGCRHAIIPDRIEAGTYMI
AAAATGNEVVIDNVIPQHVESLTAKLREMGVHVETGADQIWICGSDVLKAVDVKTLVYPGFPTDLQQPLTALLTKADGTS
VVTDTIYSARFKHIDELRRMNANVKVEGRSAIITGPVNLQGAKVKASDLRAGAALVIAGLMAEGVTEITGVEHIDRGYSG
LVEKLSKIGATIWREKMTDEEIEQVKNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=44.3127962085308, Blast_Score=345, Evalue=4e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45541; Mature: 45541

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIKIIGGDRLQGTIKVSGAKNSAVALIPAAILADSPVTIEGLPDISDVRILGSLIEEI
CCEEEEEECCCEEEEEEECCCCCCEEEEEEHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
GGSFWFDGKKAIIDPTNMVSMPLPNGKVKKLRASYYLMGAMLGRFKKAVVGLPGGCHLGP
CCCEEECCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RPIDQHIKGFEALGATVTNEQGAIYLRAEELRGARIFLDVVSVGATINIMLAAVRAKGRT
CCHHHHHHHHHHHCCEEECCCCEEEEEHHHCCCCEEEEEHHHCCCHHHHHHEEHHHCCCH
IIENAAKEPEIIDVATLLSNMGAKIKGAGTDVIRIDGVEKLSGCRHAIIPDRIEAGTYMI
HHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCCEEE
AAAATGNEVVIDNVIPQHVESLTAKLREMGVHVETGADQIWICGSDVLKAVDVKTLVYPG
EEECCCCEEEECCHHHHHHHHHHHHHHHCCCEEECCCCEEEEECHHHHHHHCCEEEEECC
FPTDLQQPLTALLTKADGTSVVTDTIYSARFKHIDELRRMNANVKVEGRSAIITGPVNLQ
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCC
GAKVKASDLRAGAALVIAGLMAEGVTEITGVEHIDRGYSGLVEKLSKIGATIWREKMTDE
CCEEEHHHHCCCHHHHHHHHHHHCHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
EIEQVKNA
HHHHHHCC
>Mature Secondary Structure
MDKIKIIGGDRLQGTIKVSGAKNSAVALIPAAILADSPVTIEGLPDISDVRILGSLIEEI
CCEEEEEECCCEEEEEEECCCCCCEEEEEEHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
GGSFWFDGKKAIIDPTNMVSMPLPNGKVKKLRASYYLMGAMLGRFKKAVVGLPGGCHLGP
CCCEEECCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RPIDQHIKGFEALGATVTNEQGAIYLRAEELRGARIFLDVVSVGATINIMLAAVRAKGRT
CCHHHHHHHHHHHCCEEECCCCEEEEEHHHCCCCEEEEEHHHCCCHHHHHHEEHHHCCCH
IIENAAKEPEIIDVATLLSNMGAKIKGAGTDVIRIDGVEKLSGCRHAIIPDRIEAGTYMI
HHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCCEEE
AAAATGNEVVIDNVIPQHVESLTAKLREMGVHVETGADQIWICGSDVLKAVDVKTLVYPG
EEECCCCEEEECCHHHHHHHHHHHHHHHCCCEEECCCCEEEEECHHHHHHHCCEEEEECC
FPTDLQQPLTALLTKADGTSVVTDTIYSARFKHIDELRRMNANVKVEGRSAIITGPVNLQ
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCC
GAKVKASDLRAGAALVIAGLMAEGVTEITGVEHIDRGYSGLVEKLSKIGATIWREKMTDE
CCEEEHHHHCCCHHHHHHHHHHHCHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
EIEQVKNA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA