Click here to switch to the map view.

The map label for this gene is ywlE [H]

Identifier: 138896949

GI number: 138896949

Start: 3424559

End: 3425005

Strand: Reverse

Name: ywlE [H]

Synonym: GTNG_3318

Alternate gene names: 138896949

Gene position: 3425005-3424559 (Counterclockwise)

Preceding gene: 138896950

Following gene: 138896948

Centisome position: 96.47

GC content: 53.91

Gene sequence:

>447_bases
ATGCCGTACCGCATTTTGTTCGTCTGCACCGGCAATACGTGCCGGAGCCCGATGGCCGCCGCGCTTCTTGAGAGCAAGCA
GCTGCCCGGTGTCGAGGTGAAATCGGCCGGTGTATTCGCTGCGGAAGGAAGCGAAGCGTCCACCCATGCAAAAACGGTAT
TGAAAGAAAAGGGGATTGACGCGTCCCACCGTTCTTCGCTATTAAAAAAAGAACATATTGACTGGGCAACGCACGTGCTG
GCGATGACGTCCGGACATAAAGAGATGATCGTCGGACGTTTTCCGGAGGCGAAAGATAAAACATTTACGTTAAAACAGTT
CGCTTCAGGAACAGACGGTGACATCGCCGACCCGTTCGGCGGCTCGGTTGAGGTGTACCGGGCAGCTCGCGATGAGTTAG
CGGCGCTTATTGACCGCCTGGCGGAAAAATTGCAAGAGAAACAATAA

Upstream 100 bases:

>100_bases
TGGGAAAAAGTGGACTGCCCGCTTTTTTTTGTTCTTTTCCCTATGGTATATTGTTGATAAGCCATTGTTATGGTAAGCCA
TTGTTGAAGAGGTGGTTGTC

Downstream 100 bases:

>100_bases
TATCACGTGGTTAATGAGGGGGAAAACAATGGGGGGAAAACGCCGTTCGTTTGGCTTGCGTCTGAAGCTTGTCGTCTTTA
CAACAGTGCTAGCAATTATT

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MPYRILFVCTGNTCRSPMAAALLESKQLPGVEVKSAGVFAAEGSEASTHAKTVLKEKGIDASHRSSLLKKEHIDWATHVL
AMTSGHKEMIVGRFPEAKDKTFTLKQFASGTDGDIADPFGGSVEVYRAARDELAALIDRLAEKLQEKQ

Sequences:

>Translated_148_residues
MPYRILFVCTGNTCRSPMAAALLESKQLPGVEVKSAGVFAAEGSEASTHAKTVLKEKGIDASHRSSLLKKEHIDWATHVL
AMTSGHKEMIVGRFPEAKDKTFTLKQFASGTDGDIADPFGGSVEVYRAARDELAALIDRLAEKLQEKQ
>Mature_147_residues
PYRILFVCTGNTCRSPMAAALLESKQLPGVEVKSAGVFAAEGSEASTHAKTVLKEKGIDASHRSSLLKKEHIDWATHVLA
MTSGHKEMIVGRFPEAKDKTFTLKQFASGTDGDIADPFGGSVEVYRAARDELAALIDRLAEKLQEKQ

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI87081812, Length=123, Percent_Identity=36.5853658536585, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16061; Mature: 15929

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRILFVCTGNTCRSPMAAALLESKQLPGVEVKSAGVFAAEGSEASTHAKTVLKEKGID
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEECCCCEEEECCCCCHHHHHHHHHHCCCC
ASHRSSLLKKEHIDWATHVLAMTSGHKEMIVGRFPEAKDKTFTLKQFASGTDGDIADPFG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCEEEHHHHCCCCCCCCCCCCC
GSVEVYRAARDELAALIDRLAEKLQEKQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PYRILFVCTGNTCRSPMAAALLESKQLPGVEVKSAGVFAAEGSEASTHAKTVLKEKGID
CEEEEEEECCCCCCHHHHHHHHHHCCCCCCEECCCCEEEECCCCCHHHHHHHHHHCCCC
ASHRSSLLKKEHIDWATHVLAMTSGHKEMIVGRFPEAKDKTFTLKQFASGTDGDIADPFG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCCEEEHHHHCCCCCCCCCCCCC
GSVEVYRAARDELAALIDRLAEKLQEKQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798145; 9384377 [H]