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The map label for this gene is nuoN [H]

Identifier: 138896923

GI number: 138896923

Start: 3401252

End: 3402745

Strand: Reverse

Name: nuoN [H]

Synonym: GTNG_3292

Alternate gene names: 138896923

Gene position: 3402745-3401252 (Counterclockwise)

Preceding gene: 138896924

Following gene: 138896922

Centisome position: 95.84

GC content: 56.09

Gene sequence:

>1494_bases
ATGAACGATGTGTGGCAAGCAAATTGGAGCATGATGACACCCGAATGGATCGTCCTCGCGGCGGCGATCGTGCTACTATT
GATTGATTTGGTCATGCCGAAGGAACGAAGCCGCCGTCCGCTCGCTTGGGGCGCTGCCGCTGGAGCGGTGCTCGCGCTCA
TTGCGACGGCGGCCATGATTCCGGCTGATCCGGTTTCGATTTTGCACGATACGTTCCGGCTCGATGGCTTTGCGAAAGCG
TTCAAGCTCATCCTATTAGCCGGCGGGGCCCTCGCGCTTCTTCTTGTTGCCGAGTGGGAGCCGAAAGAGGGGAGTCATTA
CCGCGGGGAATTTGCCTATATGATGCTGTTTGCTTTGCTTGGAGCGATGATGACAGCGTCAAGCGGCGATTTGCTTACCT
TGTTCGTCAGCATTGAACTTTTGACGGTATCGTCGTATGTTTTGGCCGGCTTGCGCAAAACCGCAACAGCGTCGAATGAG
GCCGCGCTGAAATACGTCATTAACGGCGGCATCGCCACCGCCATCATGCTGTTTGGCATGAGTTATGTGTTCGGCTTGAC
CGGGACGACGAATCTCGGTGATATCGCACGTGAGCTGCAAGAGACGAACGAGCCGTATATGCTTGCTTTGGCCTTCCTTC
TTTTACTGATTGGCGTTTCGTTTAAGTTAGCGACCGTCCCGTTCCATATGTGGGCGCCGGACGTGTACGAAGGGGCACCC
GTTCCGGCGACGGCGTTTTTCAGCGTCGTGTCGAAAACGGCTGGTTTTGTTCTTCTTCTTCGCCTGTTTGTGACGATCTT
TGCCGCTGCGCCGGCGGAAGGCCGGGATCCATCGTCGCTCTTGTTATCGATGCAGCCAGTGATCACCGTGTTGGCGGGGC
TGACGATGATTATCGGCAACGTTGTGGCGCTCCGGCAGCGGAGCTTAAAACGGCTGCTTGCCTACTCGAGTATCGCCCAT
GCCGGCTATTTGCTCGCCGGGTTTGCCGCGATGTCGTGGGCGATGATCGATTCGCTTTGGATTTACTTGCTTGCTTATGT
GTTTATGAATATCGGGGCATTTGCCATCGTGGCGCATATCGTTAACGAAACTGGCTCTGATGATTTAGCTGGGCTCGCTG
GCTTATACCGACACCGTCCGCTTTTGGCCGCGGCGCTCGGGCTGTTTTTGCTCTCGCTCGCCGGCATTCCGGGGACGGCC
GGATTCATTGCCAAGTTCTATTTGTTCATCGGCCTTGTCGTCACCGAACCGGGTCATTACGTGCTCGCTACGGTGATGGC
GGTAACGACTGTCGTCTCGTACGTCTACTATTTCAACTTGCTCGTCCAGCTCTTTTTCCGTCCGGCTTCTCTCGCGCCGT
TGCGTCGTTTGCCGGCCGGGTTGTCAACTGCCGTAGTTCTTTGCGCGCTCGGGACGCTGGCGATCGGTTGGGTGCCAGAT
CTTGCGTACGATGTGCTCGCCCAGTTCGGACATTTTGGCGATTTTTTGCCGTAA

Upstream 100 bases:

>100_bases
TCGCCTTGATCGTGGCGGTCGGCGTGTACCCGCAGCTATTGGCTGAGCCGCTTGCCACCGTGCTGGAGACGATGATGAAC
GGGTTAGGGGGTTGATCGAC

Downstream 100 bases:

>100_bases
CGGTACAATAAGGGGAGGGGAACACCTCTCCTCTTTTTTATTTCGAATGGGAGTCCATCTCCTCGAAAGCAAGGGGGTGA
ATGGATGATGATGCCTGTTA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNDVWQANWSMMTPEWIVLAAAIVLLLIDLVMPKERSRRPLAWGAAAGAVLALIATAAMIPADPVSILHDTFRLDGFAKA
FKLILLAGGALALLLVAEWEPKEGSHYRGEFAYMMLFALLGAMMTASSGDLLTLFVSIELLTVSSYVLAGLRKTATASNE
AALKYVINGGIATAIMLFGMSYVFGLTGTTNLGDIARELQETNEPYMLALAFLLLLIGVSFKLATVPFHMWAPDVYEGAP
VPATAFFSVVSKTAGFVLLLRLFVTIFAAAPAEGRDPSSLLLSMQPVITVLAGLTMIIGNVVALRQRSLKRLLAYSSIAH
AGYLLAGFAAMSWAMIDSLWIYLLAYVFMNIGAFAIVAHIVNETGSDDLAGLAGLYRHRPLLAAALGLFLLSLAGIPGTA
GFIAKFYLFIGLVVTEPGHYVLATVMAVTTVVSYVYYFNLLVQLFFRPASLAPLRRLPAGLSTAVVLCALGTLAIGWVPD
LAYDVLAQFGHFGDFLP

Sequences:

>Translated_497_residues
MNDVWQANWSMMTPEWIVLAAAIVLLLIDLVMPKERSRRPLAWGAAAGAVLALIATAAMIPADPVSILHDTFRLDGFAKA
FKLILLAGGALALLLVAEWEPKEGSHYRGEFAYMMLFALLGAMMTASSGDLLTLFVSIELLTVSSYVLAGLRKTATASNE
AALKYVINGGIATAIMLFGMSYVFGLTGTTNLGDIARELQETNEPYMLALAFLLLLIGVSFKLATVPFHMWAPDVYEGAP
VPATAFFSVVSKTAGFVLLLRLFVTIFAAAPAEGRDPSSLLLSMQPVITVLAGLTMIIGNVVALRQRSLKRLLAYSSIAH
AGYLLAGFAAMSWAMIDSLWIYLLAYVFMNIGAFAIVAHIVNETGSDDLAGLAGLYRHRPLLAAALGLFLLSLAGIPGTA
GFIAKFYLFIGLVVTEPGHYVLATVMAVTTVVSYVYYFNLLVQLFFRPASLAPLRRLPAGLSTAVVLCALGTLAIGWVPD
LAYDVLAQFGHFGDFLP
>Mature_497_residues
MNDVWQANWSMMTPEWIVLAAAIVLLLIDLVMPKERSRRPLAWGAAAGAVLALIATAAMIPADPVSILHDTFRLDGFAKA
FKLILLAGGALALLLVAEWEPKEGSHYRGEFAYMMLFALLGAMMTASSGDLLTLFVSIELLTVSSYVLAGLRKTATASNE
AALKYVINGGIATAIMLFGMSYVFGLTGTTNLGDIARELQETNEPYMLALAFLLLLIGVSFKLATVPFHMWAPDVYEGAP
VPATAFFSVVSKTAGFVLLLRLFVTIFAAAPAEGRDPSSLLLSMQPVITVLAGLTMIIGNVVALRQRSLKRLLAYSSIAH
AGYLLAGFAAMSWAMIDSLWIYLLAYVFMNIGAFAIVAHIVNETGSDDLAGLAGLYRHRPLLAAALGLFLLSLAGIPGTA
GFIAKFYLFIGLVVTEPGHYVLATVMAVTTVVSYVYYFNLLVQLFFRPASLAPLRRLPAGLSTAVVLCALGTLAIGWVPD
LAYDVLAQFGHFGDFLP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=421, Percent_Identity=34.916864608076, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788831, Length=317, Percent_Identity=28.7066246056782, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788613, Length=379, Percent_Identity=24.5382585751979, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788614, Length=381, Percent_Identity=23.6220472440945, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788827, Length=284, Percent_Identity=24.6478873239437, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53289; Mature: 53289

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVWQANWSMMTPEWIVLAAAIVLLLIDLVMPKERSRRPLAWGAAAGAVLALIATAAMI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
PADPVSILHDTFRLDGFAKAFKLILLAGGALALLLVAEWEPKEGSHYRGEFAYMMLFALL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
GAMMTASSGDLLTLFVSIELLTVSSYVLAGLRKTATASNEAALKYVINGGIATAIMLFGM
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
SYVFGLTGTTNLGDIARELQETNEPYMLALAFLLLLIGVSFKLATVPFHMWAPDVYEGAP
HHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCCCC
VPATAFFSVVSKTAGFVLLLRLFVTIFAAAPAEGRDPSSLLLSMQPVITVLAGLTMIIGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVALRQRSLKRLLAYSSIAHAGYLLAGFAAMSWAMIDSLWIYLLAYVFMNIGAFAIVAHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNETGSDDLAGLAGLYRHRPLLAAALGLFLLSLAGIPGTAGFIAKFYLFIGLVVTEPGHY
HHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHH
VLATVMAVTTVVSYVYYFNLLVQLFFRPASLAPLRRLPAGLSTAVVLCALGTLAIGWVPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LAYDVLAQFGHFGDFLP
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDVWQANWSMMTPEWIVLAAAIVLLLIDLVMPKERSRRPLAWGAAAGAVLALIATAAMI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
PADPVSILHDTFRLDGFAKAFKLILLAGGALALLLVAEWEPKEGSHYRGEFAYMMLFALL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
GAMMTASSGDLLTLFVSIELLTVSSYVLAGLRKTATASNEAALKYVINGGIATAIMLFGM
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
SYVFGLTGTTNLGDIARELQETNEPYMLALAFLLLLIGVSFKLATVPFHMWAPDVYEGAP
HHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCCCC
VPATAFFSVVSKTAGFVLLLRLFVTIFAAAPAEGRDPSSLLLSMQPVITVLAGLTMIIGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVALRQRSLKRLLAYSSIAHAGYLLAGFAAMSWAMIDSLWIYLLAYVFMNIGAFAIVAHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNETGSDDLAGLAGLYRHRPLLAAALGLFLLSLAGIPGTAGFIAKFYLFIGLVVTEPGHY
HHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHH
VLATVMAVTTVVSYVYYFNLLVQLFFRPASLAPLRRLPAGLSTAVVLCALGTLAIGWVPD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LAYDVLAQFGHFGDFLP
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA