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The map label for this gene is ywrC [H]

Identifier: 138896917

GI number: 138896917

Start: 3395397

End: 3395846

Strand: Reverse

Name: ywrC [H]

Synonym: GTNG_3286

Alternate gene names: 138896917

Gene position: 3395846-3395397 (Counterclockwise)

Preceding gene: 138896918

Following gene: 138896916

Centisome position: 95.65

GC content: 46.67

Gene sequence:

>450_bases
GTGAAACTAGACGATATCGACCGCAAAATTCTTGAAATGTTGATTGAAGATGGCCGCATGTCGTATGTCGATATTGGGAA
AAAACTGAATCTCTCCCGTGTTGCTGTCCGCGAACGGGTGAACCAGCTCGTCAAACGTGGAATTATCGAAAAATTCACTG
TTGTCATTAATTCGGAGAAGTTCGGCAAACAAGTGTCAGCGTTTTTCGAAGTCGACTGCGAACCGGCGTATTTAGTCGAA
GTCGCGCAAAAGCTGGCGGAGAATCCGAATGTGGCGAGTTGCTATCAAATGACCGGTCCGAGCACGCTGCATATGCACGT
ACTTGTCGAAGACTTCAACGCCCTCGAGAAATTCATCAACAACGAGTTATACGCACTAGAAGGCATTACGAGAGTGGAAA
GCCATATTTTGCTGCGTCGTTTCAAAAGTCGGACGGGGTTGAAATTGTAG

Upstream 100 bases:

>100_bases
GCATAGGTAGAAGCGGGAGATAAAAAAGAAAGTGGTTTCCAACGCGCCGTTTGAACCGATATAATGATAGAAAACAGGTG
TGAGTCGGGGTGACTTTATC

Downstream 100 bases:

>100_bases
AGATTGACTGAAGCGGAACGGCGAAGCGTCACAAAAACACCTTTTTAAGGGTGTTTCTTTATTTAAATAAAAAATTCATT
TTTTTTAGACAATTGTGTAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKLDDIDRKILEMLIEDGRMSYVDIGKKLNLSRVAVRERVNQLVKRGIIEKFTVVINSEKFGKQVSAFFEVDCEPAYLVE
VAQKLAENPNVASCYQMTGPSTLHMHVLVEDFNALEKFINNELYALEGITRVESHILLRRFKSRTGLKL

Sequences:

>Translated_149_residues
MKLDDIDRKILEMLIEDGRMSYVDIGKKLNLSRVAVRERVNQLVKRGIIEKFTVVINSEKFGKQVSAFFEVDCEPAYLVE
VAQKLAENPNVASCYQMTGPSTLHMHVLVEDFNALEKFINNELYALEGITRVESHILLRRFKSRTGLKL
>Mature_149_residues
MKLDDIDRKILEMLIEDGRMSYVDIGKKLNLSRVAVRERVNQLVKRGIIEKFTVVINSEKFGKQVSAFFEVDCEPAYLVE
VAQKLAENPNVASCYQMTGPSTLHMHVLVEDFNALEKFINNELYALEGITRVESHILLRRFKSRTGLKL

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=28.0821917808219, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013199
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08280 HTH_Mga [H]

EC number: NA

Molecular weight: Translated: 17117; Mature: 17117

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDDIDRKILEMLIEDGRMSYVDIGKKLNLSRVAVRERVNQLVKRGIIEKFTVVINSEK
CCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
FGKQVSAFFEVDCEPAYLVEVAQKLAENPNVASCYQMTGPSTLHMHVLVEDFNALEKFIN
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHEECCCCCEEEEHHHHHHHHHHHHHHC
NELYALEGITRVESHILLRRFKSRTGLKL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLDDIDRKILEMLIEDGRMSYVDIGKKLNLSRVAVRERVNQLVKRGIIEKFTVVINSEK
CCCCHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
FGKQVSAFFEVDCEPAYLVEVAQKLAENPNVASCYQMTGPSTLHMHVLVEDFNALEKFIN
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHEECCCCCEEEEHHHHHHHHHHHHHHC
NELYALEGITRVESHILLRRFKSRTGLKL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]