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The map label for this gene is fabZ [H]

Identifier: 138896902

GI number: 138896902

Start: 3381622

End: 3382059

Strand: Reverse

Name: fabZ [H]

Synonym: GTNG_3271

Alternate gene names: 138896902

Gene position: 3382059-3381622 (Counterclockwise)

Preceding gene: 138896903

Following gene: 138896901

Centisome position: 95.26

GC content: 56.16

Gene sequence:

>438_bases
ATGCTCGACATCCAACAAATTCAAGCGATCATCCCGCACCGTTATCCGTTTTTGCTTGTCGACCGCATTCTTGAAATCGA
AGAAGGCAAACGCGCGGTCGGCATCAAAAACGTGAGCGCCAACGAATCGTTTTTCGCCGGCCATTTCCCGGAATACCCGG
TGATGCCCGGTGTTCTCATCGTCGAGGCGCTCGCCCAAGTCGGCGCTGTCGTCCTCCTGCAAAGTGAGGAAAACCGCGGT
CGCCTCGCCTTTTTCGCCGGCATCGACAACTGCCGCTTTAAAAAGCAAGTCCAACCAGGCGACCAACTCCGCCTCGAAGT
CGAAATTCTCCGCGCTCGTGGCTCCATCGGTAAAGGCAAAGGCGTCGCCACCGTCAACGGCGAACTTGTCTGCGAAACGG
AGCTCATGTTCGCCCTAGGCGATAAACCAGCCAACTAA

Upstream 100 bases:

>100_bases
TGGCAACACATCCTTGACGTTGTGGAAAAAGGAACATAGAAACTGAGCGGCTTGCCGCAGAACATCAACATTCTTGACTC
TAATGGAAAGGAGTGTCGCT

Downstream 100 bases:

>100_bases
CCAACACGCGCCCCGTAAAGGGCGCGTGTTTTTCGTTTCTCCCTCTGAAAAAATCCCTCCCAATTGCCAGCATGCATGAA
ATGTGTGTTTCTGGGAAAGA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLDIQQIQAIIPHRYPFLLVDRILEIEEGKRAVGIKNVSANESFFAGHFPEYPVMPGVLIVEALAQVGAVVLLQSEENRG
RLAFFAGIDNCRFKKQVQPGDQLRLEVEILRARGSIGKGKGVATVNGELVCETELMFALGDKPAN

Sequences:

>Translated_145_residues
MLDIQQIQAIIPHRYPFLLVDRILEIEEGKRAVGIKNVSANESFFAGHFPEYPVMPGVLIVEALAQVGAVVLLQSEENRG
RLAFFAGIDNCRFKKQVQPGDQLRLEVEILRARGSIGKGKGVATVNGELVCETELMFALGDKPAN
>Mature_145_residues
MLDIQQIQAIIPHRYPFLLVDRILEIEEGKRAVGIKNVSANESFFAGHFPEYPVMPGVLIVEALAQVGAVVLLQSEENRG
RLAFFAGIDNCRFKKQVQPGDQLRLEVEILRARGSIGKGKGVATVNGELVCETELMFALGDKPAN

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=49.6402877697842, Blast_Score=142, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 15946; Mature: 15946

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIQQIQAIIPHRYPFLLVDRILEIEEGKRAVGIKNVSANESFFAGHFPEYPVMPGVLI
CCCHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHH
VEALAQVGAVVLLQSEENRGRLAFFAGIDNCRFKKQVQPGDQLRLEVEILRARGSIGKGK
HHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEECCCCCCCCEEEEEEEEECCCCCCCCC
GVATVNGELVCETELMFALGDKPAN
CEEEECCCEEEEEEEEEEECCCCCC
>Mature Secondary Structure
MLDIQQIQAIIPHRYPFLLVDRILEIEEGKRAVGIKNVSANESFFAGHFPEYPVMPGVLI
CCCHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHH
VEALAQVGAVVLLQSEENRGRLAFFAGIDNCRFKKQVQPGDQLRLEVEILRARGSIGKGK
HHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEECCCCCCCCEEEEEEEEECCCCCCCCC
GVATVNGELVCETELMFALGDKPAN
CEEEECCCEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA