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The map label for this gene is fadN [H]

Identifier: 138896597

GI number: 138896597

Start: 3057695

End: 3060037

Strand: Reverse

Name: fadN [H]

Synonym: GTNG_2960

Alternate gene names: 138896597

Gene position: 3060037-3057695 (Counterclockwise)

Preceding gene: 138896599

Following gene: 138896596

Centisome position: 86.19

GC content: 53.22

Gene sequence:

>2343_bases
ATGGGCTCGGGCATTGCCGCTCATTTGGCAAACGTCGGCATCCCAACGCTGTTGCTTGACATTGTGCCGCGGGAATTAAC
GAAGGAAGAAGAAGCGAAAGGATGGACGCTTGAGCATCGACAAGTGCGCAACCGTCTCGCCAATCAAGCGCTGCAAAAAC
TGTTGAAACAAAAACCAGCGCCGCTCATGGCGAAAGACAACATTGCGCTCATCGAAACGGGCAACTTTGAAGATGATCTC
CATCGGCTCGCTGAAGTCGATTGGATTATTGAAGTCGTCGTTGAAAACTTAGACGTGAAAAAAAGTGTGTTGGCCCGCGT
TGATGAAGTGCGGACGCCGGGAACGATCGTCAGCTCGAACACGTCCGGCATCTCGATTGCAGCGATGGCGGAAGGGCGTT
CGGAGGACTTTCAAAAGCATTTTTTAGGCACGCACTTTTTCAACCCACCGCGTTATTTAAAGCTGCTGGAAATTATTCCG
ACCGAGCAGACAGACCCGGATGTCGTCGCCTATATGAAAACGTTCGCCGAGGAGGTGCTCGGCAAAGGCGTCGTCATGGC
GAAAGATACACCGAACTTTATCGCCAACCGGATCGGCACGTATGGGCTGCTTGTCACGGTCCGTGAGATGATGGAAGGCG
GGTATAGCGTCGGTGAAGTCGATTCGGTCACTGGACCGCTGATCGGACGGCCGAAAAGCGCAACGTTCCGCACGCTTGAT
GTTGTCGGACTCGATACGTTTGTACATGTTGCGAACAACGTGTACGAAAACGTCGAGGGAGAAGAAAAAGATGCGTTCCG
CGTGCCGGAGTTCATGAAAGCGATGCTTGGAAACGGCTGGCTCGGCAGCAAATCCGGACAAGGCTTTTTCCTCAAACAAG
GAAAAGACATTCTCGAGCTCAATTACATCACGATGCAATACGAACCACGCAAAAAGTTGGTCACGCCGGCGGTGGAGATG
GCGAAGCAGGCAAAGGGTGCGTCCGCCAAGCTGCAAACGCTCGTGTACGCCGACGGTGACCGCGCAGGCACGCTTTTATG
GAACATCATCGCGCCGACGCTTCTGTATACCGCTCAGCTCGTCGGTGAGATCGCTGATGACATCGTGGCGATCGACCGAG
CGATGAAATGGGGGTTCGGCTGGGAACAAGGCCCGTTTGAATTGTGGGATGCGATCGGATTGGAACGGTCGGTGCGGAAA
ATGCAGGCTGAAGGGCGTGACATCCCGGCATGGATTACAAATATGCTTGCCGATGGCGCCACGGCATTCTATAAAACGGA
GAACGGCCAATTGTTCTATTATGCGCCTGACGGCTATAAAGTAGTGGAAGAAAACGAAAAAATCGTTCATATCCGTCGTC
TGAAAGAGACGCGCGGCGTCATCAAGAAAAACGCCGGCGCAAGCCTCATTGATCTCGGTGATGACGTGGCGCTCCTTGAG
TTCCATTCACCAAACAATGCGATCGGCACCGACATCGTGCAAATGATCAACGAATCGCTTGATGAAGTGAACCGCAACTA
CAAAGGACTTGTCATCGGCAACCAAGGGAAAAACTTCTGCGTCGGCGCGAATCTCGCGATGATGTTGATGGAAGCGCAGG
ACGAAAACTTCTTTGAACTCGAACTGGCGGTTCGGCAGTTCCAGCAAGCGCTTCTCAAGATGAAGTACAATCCGAAGCCG
GTCGTCGTTGCACCGTTTGCCATGACGTTAGGCGGCGGGGCGGAAGTGAGCTTGGCAGCTTCTCACATCCAGGCAGCGGC
CGAGACGTACATGGGGCTTGTGGAAGTCGGCGTCGGTTTGATTCCGGGTGGCGGCGGCAACAAGGAGTTGTACATCAAAC
GGTTGAACAGCCTGCCAAACGGTGCGGATGTCGATTATGTTAAAGTGGCTGCCAAAACGTTTGAAACGATCGCTATGGCG
AAAGTGTCGACGTCAGCGGCTGAAGCGCGTGAGCTCGGCTTCTTAAACAGCCACGATGGCATTACGATAAACAGCGATCA
TCTTCTTTACGAAGCGAAACAAGCGGTGCTCGCCTTATATGAAGACGGCTATCGCCCGCCTGTAAGGAAGAAAGTGCCGG
TGGCCGGCGAAAGCGGCTATGCCGCCATGTTGCTTGGCGCGCAATCGATGTTCCATTCCGGCTACATTAGCGAGCACGAT
TTGAAAATTGCCAAAAAGCTGGCGTACGTCTTGGCTGGCGGCAACGTGCCATACGGAACGGAAGTGGATGAACAATACTT
GCTCGACCTTGAGCGAGAAGCGTTTTTAAGCTTGATCGGCGAGCCAAAGACGCAAGCGAGAATGCAACATATGCTTGTCA
AAGGAAAACCGCTCCGCAACTAA

Upstream 100 bases:

>100_bases
TTTTTTCACCGAAAAATGAATGACGGCTCATTCAATGGTGTAAGGGGGAACAGGAATGGTGAAACGCATTCGGCGCGCTG
CTGTGCTTGGGTCTGGCGTC

Downstream 100 bases:

>100_bases
GGCGGACGAATGTTGAGGGGGGATTGGCGTGAGAGAAGCGGTGATTGTCGCAGGAGCGCGCACACCGGTCGGGAAAGCGA
AAAAAGGGACGCTCGCTCAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHRQVRNRLANQALQKLLKQKPAPLMAKDNIALIETGNFEDDL
HRLAEVDWIIEVVVENLDVKKSVLARVDEVRTPGTIVSSNTSGISIAAMAEGRSEDFQKHFLGTHFFNPPRYLKLLEIIP
TEQTDPDVVAYMKTFAEEVLGKGVVMAKDTPNFIANRIGTYGLLVTVREMMEGGYSVGEVDSVTGPLIGRPKSATFRTLD
VVGLDTFVHVANNVYENVEGEEKDAFRVPEFMKAMLGNGWLGSKSGQGFFLKQGKDILELNYITMQYEPRKKLVTPAVEM
AKQAKGASAKLQTLVYADGDRAGTLLWNIIAPTLLYTAQLVGEIADDIVAIDRAMKWGFGWEQGPFELWDAIGLERSVRK
MQAEGRDIPAWITNMLADGATAFYKTENGQLFYYAPDGYKVVEENEKIVHIRRLKETRGVIKKNAGASLIDLGDDVALLE
FHSPNNAIGTDIVQMINESLDEVNRNYKGLVIGNQGKNFCVGANLAMMLMEAQDENFFELELAVRQFQQALLKMKYNPKP
VVVAPFAMTLGGGAEVSLAASHIQAAAETYMGLVEVGVGLIPGGGGNKELYIKRLNSLPNGADVDYVKVAAKTFETIAMA
KVSTSAAEARELGFLNSHDGITINSDHLLYEAKQAVLALYEDGYRPPVRKKVPVAGESGYAAMLLGAQSMFHSGYISEHD
LKIAKKLAYVLAGGNVPYGTEVDEQYLLDLEREAFLSLIGEPKTQARMQHMLVKGKPLRN

Sequences:

>Translated_780_residues
MGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHRQVRNRLANQALQKLLKQKPAPLMAKDNIALIETGNFEDDL
HRLAEVDWIIEVVVENLDVKKSVLARVDEVRTPGTIVSSNTSGISIAAMAEGRSEDFQKHFLGTHFFNPPRYLKLLEIIP
TEQTDPDVVAYMKTFAEEVLGKGVVMAKDTPNFIANRIGTYGLLVTVREMMEGGYSVGEVDSVTGPLIGRPKSATFRTLD
VVGLDTFVHVANNVYENVEGEEKDAFRVPEFMKAMLGNGWLGSKSGQGFFLKQGKDILELNYITMQYEPRKKLVTPAVEM
AKQAKGASAKLQTLVYADGDRAGTLLWNIIAPTLLYTAQLVGEIADDIVAIDRAMKWGFGWEQGPFELWDAIGLERSVRK
MQAEGRDIPAWITNMLADGATAFYKTENGQLFYYAPDGYKVVEENEKIVHIRRLKETRGVIKKNAGASLIDLGDDVALLE
FHSPNNAIGTDIVQMINESLDEVNRNYKGLVIGNQGKNFCVGANLAMMLMEAQDENFFELELAVRQFQQALLKMKYNPKP
VVVAPFAMTLGGGAEVSLAASHIQAAAETYMGLVEVGVGLIPGGGGNKELYIKRLNSLPNGADVDYVKVAAKTFETIAMA
KVSTSAAEARELGFLNSHDGITINSDHLLYEAKQAVLALYEDGYRPPVRKKVPVAGESGYAAMLLGAQSMFHSGYISEHD
LKIAKKLAYVLAGGNVPYGTEVDEQYLLDLEREAFLSLIGEPKTQARMQHMLVKGKPLRN
>Mature_779_residues
GSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHRQVRNRLANQALQKLLKQKPAPLMAKDNIALIETGNFEDDLH
RLAEVDWIIEVVVENLDVKKSVLARVDEVRTPGTIVSSNTSGISIAAMAEGRSEDFQKHFLGTHFFNPPRYLKLLEIIPT
EQTDPDVVAYMKTFAEEVLGKGVVMAKDTPNFIANRIGTYGLLVTVREMMEGGYSVGEVDSVTGPLIGRPKSATFRTLDV
VGLDTFVHVANNVYENVEGEEKDAFRVPEFMKAMLGNGWLGSKSGQGFFLKQGKDILELNYITMQYEPRKKLVTPAVEMA
KQAKGASAKLQTLVYADGDRAGTLLWNIIAPTLLYTAQLVGEIADDIVAIDRAMKWGFGWEQGPFELWDAIGLERSVRKM
QAEGRDIPAWITNMLADGATAFYKTENGQLFYYAPDGYKVVEENEKIVHIRRLKETRGVIKKNAGASLIDLGDDVALLEF
HSPNNAIGTDIVQMINESLDEVNRNYKGLVIGNQGKNFCVGANLAMMLMEAQDENFFELELAVRQFQQALLKMKYNPKPV
VVAPFAMTLGGGAEVSLAASHIQAAAETYMGLVEVGVGLIPGGGGNKELYIKRLNSLPNGADVDYVKVAAKTFETIAMAK
VSTSAAEARELGFLNSHDGITINSDHLLYEAKQAVLALYEDGYRPPVRKKVPVAGESGYAAMLLGAQSMFHSGYISEHDL
KIAKKLAYVLAGGNVPYGTEVDEQYLLDLEREAFLSLIGEPKTQARMQHMLVKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=291, Percent_Identity=30.9278350515464, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI20127408, Length=295, Percent_Identity=30.8474576271186, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI296179427, Length=308, Percent_Identity=29.2207792207792, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI261878539, Length=246, Percent_Identity=26.4227642276423, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI68989263, Length=427, Percent_Identity=22.7166276346604, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1787661, Length=313, Percent_Identity=28.4345047923323, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790281, Length=209, Percent_Identity=30.622009569378, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788682, Length=410, Percent_Identity=27.0731707317073, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553560, Length=293, Percent_Identity=26.962457337884, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17549919, Length=294, Percent_Identity=29.9319727891156, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17563036, Length=293, Percent_Identity=27.6450511945392, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=416, Percent_Identity=26.6826923076923, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17508953, Length=419, Percent_Identity=26.491646778043, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25144276, Length=296, Percent_Identity=29.0540540540541, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=298, Percent_Identity=31.2080536912752, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71985923, Length=391, Percent_Identity=25.0639386189258, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583077, Length=369, Percent_Identity=28.7262872628726, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583079, Length=369, Percent_Identity=28.7262872628726, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19921000, Length=369, Percent_Identity=28.7262872628726, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45549573, Length=265, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 85761; Mature: 85629

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHRQVRNRLANQALQKLLKQKPA
CCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PLMAKDNIALIETGNFEDDLHRLAEVDWIIEVVVENLDVKKSVLARVDEVRTPGTIVSSN
CCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECC
TSGISIAAMAEGRSEDFQKHFLGTHFFNPPRYLKLLEIIPTEQTDPDVVAYMKTFAEEVL
CCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GKGVVMAKDTPNFIANRIGTYGLLVTVREMMEGGYSVGEVDSVTGPLIGRPKSATFRTLD
CCCEEEECCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEE
VVGLDTFVHVANNVYENVEGEEKDAFRVPEFMKAMLGNGWLGSKSGQGFFLKQGKDILEL
EHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEE
NYITMQYEPRKKLVTPAVEMAKQAKGASAKLQTLVYADGDRAGTLLWNIIAPTLLYTAQL
EEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
VGEIADDIVAIDRAMKWGFGWEQGPFELWDAIGLERSVRKMQAEGRDIPAWITNMLADGA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHCCC
TAFYKTENGQLFYYAPDGYKVVEENEKIVHIRRLKETRGVIKKNAGASLIDLGDDVALLE
EEEEEECCCEEEEECCCCCEEECCCCCEEHHHHHHHHHHHHHCCCCCCEEECCCCEEEEE
FHSPNNAIGTDIVQMINESLDEVNRNYKGLVIGNQGKNFCVGANLAMMLMEAQDENFFEL
EECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCHHHHHHHCCCCCEEHH
ELAVRQFQQALLKMKYNPKPVVVAPFAMTLGGGAEVSLAASHIQAAAETYMGLVEVGVGL
HHHHHHHHHHHHHCCCCCCCEEEECHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCEE
IPGGGGNKELYIKRLNSLPNGADVDYVKVAAKTFETIAMAKVSTSAAEARELGFLNSHDG
ECCCCCCHHHHHEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ITINSDHLLYEAKQAVLALYEDGYRPPVRKKVPVAGESGYAAMLLGAQSMFHSGYISEHD
EEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCHHH
LKIAKKLAYVLAGGNVPYGTEVDEQYLLDLEREAFLSLIGEPKTQARMQHMLVKGKPLRN
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHRQVRNRLANQALQKLLKQKPA
CCCHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PLMAKDNIALIETGNFEDDLHRLAEVDWIIEVVVENLDVKKSVLARVDEVRTPGTIVSSN
CCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECC
TSGISIAAMAEGRSEDFQKHFLGTHFFNPPRYLKLLEIIPTEQTDPDVVAYMKTFAEEVL
CCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GKGVVMAKDTPNFIANRIGTYGLLVTVREMMEGGYSVGEVDSVTGPLIGRPKSATFRTLD
CCCEEEECCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEE
VVGLDTFVHVANNVYENVEGEEKDAFRVPEFMKAMLGNGWLGSKSGQGFFLKQGKDILEL
EHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEE
NYITMQYEPRKKLVTPAVEMAKQAKGASAKLQTLVYADGDRAGTLLWNIIAPTLLYTAQL
EEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
VGEIADDIVAIDRAMKWGFGWEQGPFELWDAIGLERSVRKMQAEGRDIPAWITNMLADGA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHCCC
TAFYKTENGQLFYYAPDGYKVVEENEKIVHIRRLKETRGVIKKNAGASLIDLGDDVALLE
EEEEEECCCEEEEECCCCCEEECCCCCEEHHHHHHHHHHHHHCCCCCCEEECCCCEEEEE
FHSPNNAIGTDIVQMINESLDEVNRNYKGLVIGNQGKNFCVGANLAMMLMEAQDENFFEL
EECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCHHHHHHHCCCCCEEHH
ELAVRQFQQALLKMKYNPKPVVVAPFAMTLGGGAEVSLAASHIQAAAETYMGLVEVGVGL
HHHHHHHHHHHHHCCCCCCCEEEECHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCEE
IPGGGGNKELYIKRLNSLPNGADVDYVKVAAKTFETIAMAKVSTSAAEARELGFLNSHDG
ECCCCCCHHHHHEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ITINSDHLLYEAKQAVLALYEDGYRPPVRKKVPVAGESGYAAMLLGAQSMFHSGYISEHD
EEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCHHH
LKIAKKLAYVLAGGNVPYGTEVDEQYLLDLEREAFLSLIGEPKTQARMQHMLVKGKPLRN
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]