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The map label for this gene is mreD [H]

Identifier: 138896182

GI number: 138896182

Start: 2647835

End: 2648353

Strand: Reverse

Name: mreD [H]

Synonym: GTNG_2545

Alternate gene names: 138896182

Gene position: 2648353-2647835 (Counterclockwise)

Preceding gene: 138896183

Following gene: 138896181

Centisome position: 74.59

GC content: 47.78

Gene sequence:

>519_bases
GTGAAAAAGTGGCAGCTCCCTTTCCTTGCGGTGTTATGTTTTGTCAGCGAAAGCATTTTTGTTGATGTATGGCCGAAGGG
TGACTTATATATTCGCTATTTTTTTGTGCCCCGTTTTTTTCTCGTTTTTTTAGTGCTAATGGCTGTTTACCTTGGCGGGA
CGCGGGCGATGGGCTACGGCTTCATTTTCGGGTTCCTATATGATTGCATCTATACGGAACTGCTCGGTGTTAACGCCTTT
GCCTATACGCTCATCGCCTATATAGCGGGCAAAGCAACAAAATGGTTTCACCAGAGCTGGGCGGTTGCGTTTTTGTTATC
GGTGTTGGCTATTGCCCTGCTTGACAGTTATGTGTACGGCATTCAGCTGTTGATCGGGCGGACAGATTGGTCGTTTTCTG
TTTTTTGGGATCGCCGGTTATGGCCGACGCTGCTGTTAAACATCGCATTTTTGCTCATCTTCTCGTACCCGCTCGGACGG
TGGCTGACCAAAATTCGCCGATTGGAGCAGGAAGAATAA

Upstream 100 bases:

>100_bases
TCGTCTATGTCAAACCGTTTGCCAACTTGTATGATATTGACGATGTAATGATTGTGAAACGAAAAATCGATAAGACACTG
CAAGAAGAGGAGGAGGCAAA

Downstream 100 bases:

>100_bases
AAGAGGAAAAACGGCCCGTTCTGTAGAATTATTCGTTGGGGTGAACGTTGTGGCAAAACAAAAGCAGCAGTACGTGACGA
TTAAAGGGACGAAAGATGGG

Product: cell-shape determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKKWQLPFLAVLCFVSESIFVDVWPKGDLYIRYFFVPRFFLVFLVLMAVYLGGTRAMGYGFIFGFLYDCIYTELLGVNAF
AYTLIAYIAGKATKWFHQSWAVAFLLSVLAIALLDSYVYGIQLLIGRTDWSFSVFWDRRLWPTLLLNIAFLLIFSYPLGR
WLTKIRRLEQEE

Sequences:

>Translated_172_residues
MKKWQLPFLAVLCFVSESIFVDVWPKGDLYIRYFFVPRFFLVFLVLMAVYLGGTRAMGYGFIFGFLYDCIYTELLGVNAF
AYTLIAYIAGKATKWFHQSWAVAFLLSVLAIALLDSYVYGIQLLIGRTDWSFSVFWDRRLWPTLLLNIAFLLIFSYPLGR
WLTKIRRLEQEE
>Mature_172_residues
MKKWQLPFLAVLCFVSESIFVDVWPKGDLYIRYFFVPRFFLVFLVLMAVYLGGTRAMGYGFIFGFLYDCIYTELLGVNAF
AYTLIAYIAGKATKWFHQSWAVAFLLSVLAIALLDSYVYGIQLLIGRTDWSFSVFWDRRLWPTLLLNIAFLLIFSYPLGR
WLTKIRRLEQEE

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 20197; Mature: 20197

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWQLPFLAVLCFVSESIFVDVWPKGDLYIRYFFVPRFFLVFLVLMAVYLGGTRAMGYG
CCCCCHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FIFGFLYDCIYTELLGVNAFAYTLIAYIAGKATKWFHQSWAVAFLLSVLAIALLDSYVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQLLIGRTDWSFSVFWDRRLWPTLLLNIAFLLIFSYPLGRWLTKIRRLEQEE
HHHHEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKWQLPFLAVLCFVSESIFVDVWPKGDLYIRYFFVPRFFLVFLVLMAVYLGGTRAMGYG
CCCCCHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FIFGFLYDCIYTELLGVNAFAYTLIAYIAGKATKWFHQSWAVAFLLSVLAIALLDSYVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQLLIGRTDWSFSVFWDRRLWPTLLLNIAFLLIFSYPLGRWLTKIRRLEQEE
HHHHEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]