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The map label for this gene is pheA [H]

Identifier: 138896171

GI number: 138896171

Start: 2639579

End: 2640427

Strand: Reverse

Name: pheA [H]

Synonym: GTNG_2534

Alternate gene names: 138896171

Gene position: 2640427-2639579 (Counterclockwise)

Preceding gene: 138896172

Following gene: 138896168

Centisome position: 74.37

GC content: 52.65

Gene sequence:

>849_bases
ATGAGAATCGGCTATTTAGGACCGAAGGCGACGTTTACTGAAGCGGCCGTTGCGGCGCTATTTCCATCAGAGCCGCGACA
GCCGTACGCCACGATTCCCGACTGCATCGATGCTGTCGCTGCTGGGGAAATTGAGGCAGCGGTTGTGCCGCTTGAGAATG
CGTTGGAAGGGTCGGTCAATTTAACGCTCGATTATTTAATCCATGAACAGCCGTTGCCGATCATCGGTGAAATCGTTGTT
CCGATTGAGCAGCATTTCATGGTGCATCCGTACTATGCACCGCATTGGCGGGAGATTAAAGAAGTGTATTCACATTCGCA
TGCCATTGCTCAGTGCCGCAAATTTTTACATACGGTGCTCAAAGGCGCAAAGCAAGTGCCCACGACGTCAACGAGCGCCG
CTGCCAAATTTGTCAGCGAACATCCGCACTTGCCAGTGGCGGCGATTGCCAATCGGCTCGCAGCGAGCGAATACGGCTTG
ACGATTGTGCAGGAAAATATTCATGATTATGATTACAACCATACGCGCTTTATCGTCGTCAGCCGAAGCAGGCAGCCGCT
TTCGCCTGATTCGCCGCTTTATGCCGGCGACAAAACGACCATTGTTGTCATGTTGCCGCAAGATCAGCCTGGTGCGCTCC
ACCAAGTGCTGTCGGCGTTTGCTTGGCGGCGGCTGAACTTGACGAAAATCGAGTCGCGCCCAGCGAAAACAGGGCTTGGC
AACTACTTTTTTATCATTGATATTGACGCACCGATGGATGATGTCCTCATCCCGGGAGCGATCGCCGAAATCGAAGCGCT
CGGCTGTACGGTGCAACTGTTAGGCAGCTATCCATATTACTTTGTCTAA

Upstream 100 bases:

>100_bases
CATTGATGAACTGTTGGCAAAACTTAGGGGGCTTGAATTTGTCGAAAAAGTTGAAATTGTCGGCTCGGGAGTGTATTAAA
GCAAGGGAGAGGCAAACGAG

Downstream 100 bases:

>100_bases
AACACCAGGGTGTCCCAAAACTAGGAGGACACCCTTTCCTATCATGGCATATGTGTACTAGGTCATTTTATGAGAGACGA
GATGTTATCTCCCTCGTAAA

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRIGYLGPKATFTEAAVAALFPSEPRQPYATIPDCIDAVAAGEIEAAVVPLENALEGSVNLTLDYLIHEQPLPIIGEIVV
PIEQHFMVHPYYAPHWREIKEVYSHSHAIAQCRKFLHTVLKGAKQVPTTSTSAAAKFVSEHPHLPVAAIANRLAASEYGL
TIVQENIHDYDYNHTRFIVVSRSRQPLSPDSPLYAGDKTTIVVMLPQDQPGALHQVLSAFAWRRLNLTKIESRPAKTGLG
NYFFIIDIDAPMDDVLIPGAIAEIEALGCTVQLLGSYPYYFV

Sequences:

>Translated_282_residues
MRIGYLGPKATFTEAAVAALFPSEPRQPYATIPDCIDAVAAGEIEAAVVPLENALEGSVNLTLDYLIHEQPLPIIGEIVV
PIEQHFMVHPYYAPHWREIKEVYSHSHAIAQCRKFLHTVLKGAKQVPTTSTSAAAKFVSEHPHLPVAAIANRLAASEYGL
TIVQENIHDYDYNHTRFIVVSRSRQPLSPDSPLYAGDKTTIVVMLPQDQPGALHQVLSAFAWRRLNLTKIESRPAKTGLG
NYFFIIDIDAPMDDVLIPGAIAEIEALGCTVQLLGSYPYYFV
>Mature_282_residues
MRIGYLGPKATFTEAAVAALFPSEPRQPYATIPDCIDAVAAGEIEAAVVPLENALEGSVNLTLDYLIHEQPLPIIGEIVV
PIEQHFMVHPYYAPHWREIKEVYSHSHAIAQCRKFLHTVLKGAKQVPTTSTSAAAKFVSEHPHLPVAAIANRLAASEYGL
TIVQENIHDYDYNHTRFIVVSRSRQPLSPDSPLYAGDKTTIVVMLPQDQPGALHQVLSAFAWRRLNLTKIESRPAKTGLG
NYFFIIDIDAPMDDVLIPGAIAEIEALGCTVQLLGSYPYYFV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=281, Percent_Identity=30.9608540925267, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324013, Length=275, Percent_Identity=28, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31096; Mature: 31096

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGYLGPKATFTEAAVAALFPSEPRQPYATIPDCIDAVAAGEIEAAVVPLENALEGSVN
CEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECHHHCCCCEE
LTLDYLIHEQPLPIIGEIVVPIEQHFMVHPYYAPHWREIKEVYSHSHAIAQCRKFLHTVL
EEEEEEECCCCCCCHHHEEECCHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KGAKQVPTTSTSAAAKFVSEHPHLPVAAIANRLAASEYGLTIVQENIHDYDYNHTRFIVV
HCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEE
SRSRQPLSPDSPLYAGDKTTIVVMLPQDQPGALHQVLSAFAWRRLNLTKIESRPAKTGLG
ECCCCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
NYFFIIDIDAPMDDVLIPGAIAEIEALGCTVQLLGSYPYYFV
CEEEEEEECCCCCCEECCCHHHHHHHHCHHEEECCCCCCEEC
>Mature Secondary Structure
MRIGYLGPKATFTEAAVAALFPSEPRQPYATIPDCIDAVAAGEIEAAVVPLENALEGSVN
CEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECHHHCCCCEE
LTLDYLIHEQPLPIIGEIVVPIEQHFMVHPYYAPHWREIKEVYSHSHAIAQCRKFLHTVL
EEEEEEECCCCCCCHHHEEECCHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KGAKQVPTTSTSAAAKFVSEHPHLPVAAIANRLAASEYGLTIVQENIHDYDYNHTRFIVV
HCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEE
SRSRQPLSPDSPLYAGDKTTIVVMLPQDQPGALHQVLSAFAWRRLNLTKIESRPAKTGLG
ECCCCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
NYFFIIDIDAPMDDVLIPGAIAEIEALGCTVQLLGSYPYYFV
CEEEEEEECCCCCCEECCCHHHHHHHHCHHEEECCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]