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The map label for this gene is nadA

Identifier: 138896166

GI number: 138896166

Start: 2633971

End: 2635074

Strand: Reverse

Name: nadA

Synonym: GTNG_2529

Alternate gene names: 138896166

Gene position: 2635074-2633971 (Counterclockwise)

Preceding gene: 138896167

Following gene: 138896165

Centisome position: 74.22

GC content: 51.54

Gene sequence:

>1104_bases
ATGAACGTACTCGAACAGTTCAAACAGCTCGATAATATGCCGGAACAGTATAAAACGATGGACAGAGATGAGCTCGAAGC
GCGCGCCCGCGCGGTGAAGGAGCAGCTCGGGCGGCGTCTTTTTATCCCTGGACATCATTACCAAAAAGATGAGGTCATTC
AGTTCGCTGATGCCACCGGCGACTCGCTTCAGCTCGCCCAACTGGCGGCGAAAAACAACGAAGCGGAATATATTGTGTTT
TGCGGCGTCCATTTCATGGCGGAAACCGCGGACATTTTAACGAGTGAGGAGCAGACAGTTATTTTGCCGGACTTGCGCGC
TGGCTGTTCGATGGCCGATATGGCCGATGTTTTTCAAGTTGAGCGGGCATGGGCGGCATTGACGGATCGATTTGGCGAGA
CGATTCTGCCGCTTGTATACGTCAATTCCACAGCGGCGATTAAAGCGTTTGTCGGCCGAAATGGAGGGGCGACGGTTACG
TCGTCCAACGCGCAAAAGATGGTAGCGTGGGCGTTTTCACAAAAAGAACGGATCTTCTTTTTACCGGACCAGCATTTAGG
CCGAAATACGGCCTATGCACTCGGCGTTGGCCTTGACGAGATGGCCGTCTGGGATCCATATGAGGAAACATTGCAAGGCA
ACGGTGACTTTGACAAGGTGAAAGTCATTCTTTGGAAGGGCCATTGCTCGGTGCATGAAAACTTCAATGTCCGGCAAATC
GAGCATATTCGGCAGACGAAACCGGAAACAAAGGTAATCGTCCATCCGGAATGCAGCTGGGACGTCGTCCAGCAAGCCGA
TTACGCCGGTTCAACAAAATACATTATCGAAACGATTCGCAACGCCTCACCCGGTAGCCGATGGGCGATCGGAACAGAAA
TGAATTTGGTGAATCGCCTTATGCATGAGCATCCGGACAAAGAAATCATTTCTCTTAATCCGTATATGTGCCCGTGTTTG
ACGATGAACCGGATCGATTTGCCGCATTTCGTTTGGGCGTTGGAATCGCTCAGTGAAGGAACAGTCGTCAACCGCATTAC
CGTTCCAAAGGAAGTAGCGTTCGAAGCAAAGCTAGCGCTCGAGCGCATGCTTGCCCTTGCCTAG

Upstream 100 bases:

>100_bases
ACGGTGCGACCGGAGTCGACTACATTTCACTTGGGTTTTTAACGCATTCAGCTGCAGCGTTGGACATTAGTTTTTATTTA
CAATGACGGAGGAGAGAATG

Downstream 100 bases:

>100_bases
TTCTCCTCCCTGGCGAAGACGGGATCGCTTCCGTCCGGCCAGGGATTTTTTTATCATAAATCAACAACCATCGTCATACA
TTGTGTTGAAAGATGATAAC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNVLEQFKQLDNMPEQYKTMDRDELEARARAVKEQLGRRLFIPGHHYQKDEVIQFADATGDSLQLAQLAAKNNEAEYIVF
CGVHFMAETADILTSEEQTVILPDLRAGCSMADMADVFQVERAWAALTDRFGETILPLVYVNSTAAIKAFVGRNGGATVT
SSNAQKMVAWAFSQKERIFFLPDQHLGRNTAYALGVGLDEMAVWDPYEETLQGNGDFDKVKVILWKGHCSVHENFNVRQI
EHIRQTKPETKVIVHPECSWDVVQQADYAGSTKYIIETIRNASPGSRWAIGTEMNLVNRLMHEHPDKEIISLNPYMCPCL
TMNRIDLPHFVWALESLSEGTVVNRITVPKEVAFEAKLALERMLALA

Sequences:

>Translated_367_residues
MNVLEQFKQLDNMPEQYKTMDRDELEARARAVKEQLGRRLFIPGHHYQKDEVIQFADATGDSLQLAQLAAKNNEAEYIVF
CGVHFMAETADILTSEEQTVILPDLRAGCSMADMADVFQVERAWAALTDRFGETILPLVYVNSTAAIKAFVGRNGGATVT
SSNAQKMVAWAFSQKERIFFLPDQHLGRNTAYALGVGLDEMAVWDPYEETLQGNGDFDKVKVILWKGHCSVHENFNVRQI
EHIRQTKPETKVIVHPECSWDVVQQADYAGSTKYIIETIRNASPGSRWAIGTEMNLVNRLMHEHPDKEIISLNPYMCPCL
TMNRIDLPHFVWALESLSEGTVVNRITVPKEVAFEAKLALERMLALA
>Mature_367_residues
MNVLEQFKQLDNMPEQYKTMDRDELEARARAVKEQLGRRLFIPGHHYQKDEVIQFADATGDSLQLAQLAAKNNEAEYIVF
CGVHFMAETADILTSEEQTVILPDLRAGCSMADMADVFQVERAWAALTDRFGETILPLVYVNSTAAIKAFVGRNGGATVT
SSNAQKMVAWAFSQKERIFFLPDQHLGRNTAYALGVGLDEMAVWDPYEETLQGNGDFDKVKVILWKGHCSVHENFNVRQI
EHIRQTKPETKVIVHPECSWDVVQQADYAGSTKYIIETIRNASPGSRWAIGTEMNLVNRLMHEHPDKEIISLNPYMCPCL
TMNRIDLPHFVWALESLSEGTVVNRITVPKEVAFEAKLALERMLALA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=352, Percent_Identity=28.9772727272727, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_GEOTN (A4IRC0)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126619.1
- ProteinModelPortal:   A4IRC0
- SMR:   A4IRC0
- STRING:   A4IRC0
- GeneID:   4967455
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2529
- NMPDR:   fig|420246.5.peg.2436
- eggNOG:   COG0379
- HOGENOM:   HBG291157
- OMA:   GTELNLV
- PhylomeDB:   A4IRC0
- ProtClustDB:   PRK09375
- BioCyc:   GTHE420246:GTNG_2529-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 41447; Mature: 41447

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: BINDING 45-45 BINDING 62-62 BINDING 140-140 BINDING 161-161 BINDING 255-255 BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLEQFKQLDNMPEQYKTMDRDELEARARAVKEQLGRRLFIPGHHYQKDEVIQFADATG
CCHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHEEECCCC
DSLQLAQLAAKNNEAEYIVFCGVHFMAETADILTSEEQTVILPDLRAGCSMADMADVFQV
CCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHH
ERAWAALTDRFGETILPLVYVNSTAAIKAFVGRNGGATVTSSNAQKMVAWAFSQKERIFF
HHHHHHHHHHHCCCEEEEEEECCHHHEEHEECCCCCCEEECCCCCEEEHEEECCCCEEEE
LPDQHLGRNTAYALGVGLDEMAVWDPYEETLQGNGDFDKVKVILWKGHCSVHENFNVRQI
CCCHHCCCCCEEEEECCCHHHHCCCCHHHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHH
EHIRQTKPETKVIVHPECSWDVVQQADYAGSTKYIIETIRNASPGSRWAIGTEMNLVNRL
HHHHHCCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHH
MHEHPDKEIISLNPYMCPCLTMNRIDLPHFVWALESLSEGTVVNRITVPKEVAFEAKLAL
HHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHH
ERMLALA
HHHHHCC
>Mature Secondary Structure
MNVLEQFKQLDNMPEQYKTMDRDELEARARAVKEQLGRRLFIPGHHYQKDEVIQFADATG
CCHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHEEECCCC
DSLQLAQLAAKNNEAEYIVFCGVHFMAETADILTSEEQTVILPDLRAGCSMADMADVFQV
CCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHH
ERAWAALTDRFGETILPLVYVNSTAAIKAFVGRNGGATVTSSNAQKMVAWAFSQKERIFF
HHHHHHHHHHHCCCEEEEEEECCHHHEEHEECCCCCCEEECCCCCEEEHEEECCCCEEEE
LPDQHLGRNTAYALGVGLDEMAVWDPYEETLQGNGDFDKVKVILWKGHCSVHENFNVRQI
CCCHHCCCCCEEEEECCCHHHHCCCCHHHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHH
EHIRQTKPETKVIVHPECSWDVVQQADYAGSTKYIIETIRNASPGSRWAIGTEMNLVNRL
HHHHHCCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHHH
MHEHPDKEIISLNPYMCPCLTMNRIDLPHFVWALESLSEGTVVNRITVPKEVAFEAKLAL
HHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHH
ERMLALA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA