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The map label for this gene is cymR [H]

Identifier: 138896135

GI number: 138896135

Start: 2601075

End: 2601494

Strand: Reverse

Name: cymR [H]

Synonym: GTNG_2498

Alternate gene names: 138896135

Gene position: 2601494-2601075 (Counterclockwise)

Preceding gene: 138896136

Following gene: 138896134

Centisome position: 73.27

GC content: 50.48

Gene sequence:

>420_bases
ATGATGAAAATCTCGACGAAGGGCCGGTACGGGTTGACGATTATGATCGAATTAGCCAAAAAATATGGGGATCGTCCGAT
TTCGCTTCGTTCGATCGCCAGGGCGAACAATTTATCCGAACATTATTTGGAACAACTTGTCACGCCGCTGCGCAACGCTG
GGCTCGTCAAAAGCATTCGTGGGGCGTATGGCGGTTACGTGCTTGCCGAGCATCCGGCCAAAATTACGGCCGGCGATATT
CTTCGCGTGCTTGAAGGACCGATTACTCCGGTCGAGGAACTTGAAGAGGAGGAGCCGGCAAAGCGCGAGTTGTGGATCCG
CATCCGTGATGCGGTCGAGGAAGTGCTTGATAGCACGACATTGGAAGATTTGGCGAAGTATAACGACGGAGATGAAGGAG
CATATATGTTTTATATTTAA

Upstream 100 bases:

>100_bases
CGGGGGCCGGCTTGGTGTTGCCGCAATACTGGAAAAATAACCAGCCGTCTGCTTGGAGTGACAAGCGCTCACGTGGAAGG
GTTAAGTCGTTAGGGGGGAT

Downstream 100 bases:

>100_bases
GCGATAGAAAGGAGAATGAGCGTTGGAACGGATTTATTTGGACCATGCCGCCACGGCTCCCGTGCATCCAGATGTGGCAG
CCGGTATGGTCCATTGGATG

Product: RRF2 family protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MMKISTKGRYGLTIMIELAKKYGDRPISLRSIARANNLSEHYLEQLVTPLRNAGLVKSIRGAYGGYVLAEHPAKITAGDI
LRVLEGPITPVEELEEEEPAKRELWIRIRDAVEEVLDSTTLEDLAKYNDGDEGAYMFYI

Sequences:

>Translated_139_residues
MMKISTKGRYGLTIMIELAKKYGDRPISLRSIARANNLSEHYLEQLVTPLRNAGLVKSIRGAYGGYVLAEHPAKITAGDI
LRVLEGPITPVEELEEEEPAKRELWIRIRDAVEEVLDSTTLEDLAKYNDGDEGAYMFYI
>Mature_139_residues
MMKISTKGRYGLTIMIELAKKYGDRPISLRSIARANNLSEHYLEQLVTPLRNAGLVKSIRGAYGGYVLAEHPAKITAGDI
LRVLEGPITPVEELEEEEPAKRELWIRIRDAVEEVLDSTTLEDLAKYNDGDEGAYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=129, Percent_Identity=29.4573643410853, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15655; Mature: 15655

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKISTKGRYGLTIMIELAKKYGDRPISLRSIARANNLSEHYLEQLVTPLRNAGLVKSIR
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
GAYGGYVLAEHPAKITAGDILRVLEGPITPVEELEEEEPAKRELWIRIRDAVEEVLDSTT
HHHCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
LEDLAKYNDGDEGAYMFYI
HHHHHHCCCCCCCEEEEEC
>Mature Secondary Structure
MMKISTKGRYGLTIMIELAKKYGDRPISLRSIARANNLSEHYLEQLVTPLRNAGLVKSIR
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
GAYGGYVLAEHPAKITAGDILRVLEGPITPVEELEEEEPAKRELWIRIRDAVEEVLDSTT
HHHCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
LEDLAKYNDGDEGAYMFYI
HHHHHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]