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The map label for this gene is ispG [H]

Identifier: 138896040

GI number: 138896040

Start: 2514145

End: 2515269

Strand: Direct

Name: ispG [H]

Synonym: GTNG_2403

Alternate gene names: 138896040

Gene position: 2514145-2515269 (Clockwise)

Preceding gene: 138896039

Following gene: 138896042

Centisome position: 70.81

GC content: 51.29

Gene sequence:

>1125_bases
GTGAGTGAAATCATCCATCGTTCAAAAACAAGGCCAGTCCGCGTCGGGTCGCTGACGATCGGCGGCAACAATGAAGTCAT
TATCCAAAGCATGACAACGACAAAAACACACGATGTCGACGCGACTGTAGCCCAAATTCATCGGCTTGAGGAAGCGGGCT
GCCAAATCGTCCGCGTTGCCTGTCCGGACGAACGGGCGGCTGATGCCATACCAGAAATTAAAAAGCGAATTAACATCCCG
CTTGTCGCCGACATTCACTTTGACTATAAATTGGCGTTAAAAGCGATCGAAGGCGGCGTCGATAAAATTCGCATCAACCC
GGGCAATATTGGGCGCCGAGAGAAAGTCGAGGCGGTCGTCAAAGCCGCAAAAGAACGCGGCGTGCCCATCCGTATCGGTG
TCAACGCCGGGTCGCTTGAGAAACGCATTTTGGAAAAATACGGATATCCTACAGCCGAAGGCATGGTGGAAAGCGCCTTA
TACCATATCCGCATTTTAGAGGAGCTTGATTTTCACGATATTATTGTCTCGTTAAAAGCGTCCGATGTGCGTCTCGCCAT
TGAAGCATATGAAAAAGCGGCGCGCACGTTTGACTATCCGCTTCACGTCGGCATTACCGAGGCCGGAACACTCTTTTCCG
GTACGATTAAAAGCGCGGTCGGGCTCGGTGCCATTTTAAGCAAAGGCATCGGCAATACGATCCGTATTTCCTTAAGTGCC
GATCCGGTCGAAGAAGTGAAAGTAGCGCGTGAAATTTTAAAAACGTTCGGGCTTGCCTCCAATGCGGCGACGCTCATTTC
CTGCCCGACGTGCGGACGGATTGAGATCGATTTAATCAGCATCGCCAATGAAATCGAGGACTATATCGCCAAAATTAAAG
CACCGATCAAAGTCGCCGTGCTTGGTTGCGCCGTCAACGGACCGGGTGAAGCGCGCGAAGCCGATATCGGCATTGCCGGC
GCCCGTGGCGAAGGCCTGTTGTTCCGCCACGGCAAAATTGTCCGCAAAGTGCCAGAAGAGCAGATGGTCGAAGAATTGAA
GAAAGAAATCGACAAGCTGGCTGAGGAATATTTTGCGAAACAAAAGGAAAAAGAAGCGGCTCTAAAAGGGAATGCCGTGG
AGTAA

Upstream 100 bases:

>100_bases
CGATATACGAAAAATAAACGTGGCGAATTTCTTGTCAATGCCCATCACTATTGATAAACTTAGTGCAGAAAAGCACTCGT
TTTTAAAGGAGCGAATTTCC

Downstream 100 bases:

>100_bases
TCGAAACACGGTCAAAAGAACAAAAAAGGGCGTCCTCGCTTGAGGACACCCTCGCTTTTTTTACGTATAAAACGGCATAA
TGAACAAGCGGACGAGAATG

Product: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

Products: NA

Alternate protein names: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSEIIHRSKTRPVRVGSLTIGGNNEVIIQSMTTTKTHDVDATVAQIHRLEEAGCQIVRVACPDERAADAIPEIKKRINIP
LVADIHFDYKLALKAIEGGVDKIRINPGNIGRREKVEAVVKAAKERGVPIRIGVNAGSLEKRILEKYGYPTAEGMVESAL
YHIRILEELDFHDIIVSLKASDVRLAIEAYEKAARTFDYPLHVGITEAGTLFSGTIKSAVGLGAILSKGIGNTIRISLSA
DPVEEVKVAREILKTFGLASNAATLISCPTCGRIEIDLISIANEIEDYIAKIKAPIKVAVLGCAVNGPGEAREADIGIAG
ARGEGLLFRHGKIVRKVPEEQMVEELKKEIDKLAEEYFAKQKEKEAALKGNAVE

Sequences:

>Translated_374_residues
MSEIIHRSKTRPVRVGSLTIGGNNEVIIQSMTTTKTHDVDATVAQIHRLEEAGCQIVRVACPDERAADAIPEIKKRINIP
LVADIHFDYKLALKAIEGGVDKIRINPGNIGRREKVEAVVKAAKERGVPIRIGVNAGSLEKRILEKYGYPTAEGMVESAL
YHIRILEELDFHDIIVSLKASDVRLAIEAYEKAARTFDYPLHVGITEAGTLFSGTIKSAVGLGAILSKGIGNTIRISLSA
DPVEEVKVAREILKTFGLASNAATLISCPTCGRIEIDLISIANEIEDYIAKIKAPIKVAVLGCAVNGPGEAREADIGIAG
ARGEGLLFRHGKIVRKVPEEQMVEELKKEIDKLAEEYFAKQKEKEAALKGNAVE
>Mature_373_residues
SEIIHRSKTRPVRVGSLTIGGNNEVIIQSMTTTKTHDVDATVAQIHRLEEAGCQIVRVACPDERAADAIPEIKKRINIPL
VADIHFDYKLALKAIEGGVDKIRINPGNIGRREKVEAVVKAAKERGVPIRIGVNAGSLEKRILEKYGYPTAEGMVESALY
HIRILEELDFHDIIVSLKASDVRLAIEAYEKAARTFDYPLHVGITEAGTLFSGTIKSAVGLGAILSKGIGNTIRISLSAD
PVEEVKVAREILKTFGLASNAATLISCPTCGRIEIDLISIANEIEDYIAKIKAPIKVAVLGCAVNGPGEAREADIGIAGA
RGEGLLFRHGKIVRKVPEEQMVEELKKEIDKLAEEYFAKQKEKEAALKGNAVE

Specific function: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate [H]

COG id: COG0821

COG function: function code I; Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispG family [H]

Homologues:

Organism=Escherichia coli, GI1788863, Length=346, Percent_Identity=49.1329479768786, Blast_Score=346, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011005
- InterPro:   IPR016425
- InterPro:   IPR004588 [H]

Pfam domain/function: PF04551 GcpE [H]

EC number: =1.17.7.1 [H]

Molecular weight: Translated: 40581; Mature: 40449

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIIHRSKTRPVRVGSLTIGGNNEVIIQSMTTTKTHDVDATVAQIHRLEEAGCQIVRVA
CCCHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEE
CPDERAADAIPEIKKRINIPLVADIHFDYKLALKAIEGGVDKIRINPGNIGRREKVEAVV
CCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
KAAKERGVPIRIGVNAGSLEKRILEKYGYPTAEGMVESALYHIRILEELDFHDIIVSLKA
HHHHHCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEEC
SDVRLAIEAYEKAARTFDYPLHVGITEAGTLFSGTIKSAVGLGAILSKGIGNTIRISLSA
CCEEHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
DPVEEVKVAREILKTFGLASNAATLISCPTCGRIEIDLISIANEIEDYIAKIKAPIKVAV
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEE
LGCAVNGPGEAREADIGIAGARGEGLLFRHGKIVRKVPEEQMVEELKKEIDKLAEEYFAK
EEEEECCCCCCCCCCCEEECCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QKEKEAALKGNAVE
HHHHHHHCCCCCCC
>Mature Secondary Structure 
SEIIHRSKTRPVRVGSLTIGGNNEVIIQSMTTTKTHDVDATVAQIHRLEEAGCQIVRVA
CCHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEE
CPDERAADAIPEIKKRINIPLVADIHFDYKLALKAIEGGVDKIRINPGNIGRREKVEAVV
CCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
KAAKERGVPIRIGVNAGSLEKRILEKYGYPTAEGMVESALYHIRILEELDFHDIIVSLKA
HHHHHCCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHEEEEEEC
SDVRLAIEAYEKAARTFDYPLHVGITEAGTLFSGTIKSAVGLGAILSKGIGNTIRISLSA
CCEEHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
DPVEEVKVAREILKTFGLASNAATLISCPTCGRIEIDLISIANEIEDYIAKIKAPIKVAV
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEE
LGCAVNGPGEAREADIGIAGARGEGLLFRHGKIVRKVPEEQMVEELKKEIDKLAEEYFAK
EEEEECCCCCCCCCCCEEECCCCCCEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QKEKEAALKGNAVE
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA