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The map label for this gene is yqkF [H]

Identifier: 138895893

GI number: 138895893

Start: 2368866

End: 2369786

Strand: Direct

Name: yqkF [H]

Synonym: GTNG_2252

Alternate gene names: 138895893

Gene position: 2368866-2369786 (Clockwise)

Preceding gene: 138895871

Following gene: 138895898

Centisome position: 66.72

GC content: 54.61

Gene sequence:

>921_bases
ATGAACAAACGACGCATCGGTACATCGGATTTGTATGTGAGCGAAATCGGACTCGGCTGCATGTCGCTTGGCACCGATGA
ACGCGAGGCGATCCGCCTCATTCACGAAGCGCTTGATCGCGGCATCAACTATTTGGATACAGCCGACTTGTACGACCGTG
GCCTGAACGAAGAATTTGTCGGCAAAGCGGTGAAAGGAAAACGCGATCAAGTGATTATCGCCACCAAAGTAGGCAACCGT
TGGCGACCGGACGGAAGCGGTTGGGATTGGGATCCGTCCAAAGCATATATCAAGCAAGCCGTCAAAGACAGCCTGCGCCG
CCTGCAAACAGACTACATTGACTTATACCAGCTCCACGGTGGCACGATCGACGACCCGATCGACGAGACGATTGCGGCAT
TTGAAGAGTTAAAGCAAGAAGGAGTCATTCGTTGGTACGGCATTTCCTCGATCCGTCCCAACGTCATTCGCGAATATGTG
AAGCGTTCAAATATCGTCAGCGTCATGATGCAATATAGCCTGCTTGACCGCCGTCCGGAAGAGTGGTTCCCTCTCTTGCG
CGAGCATAACATCAGCGTCATCGCCCGCGGTCCGGTCGCTAAAGGCTTGCTTACTGACCGCCCGCTCGAAGCGGCAGGAG
CGGCGGTGAAAGAACACGGCTATCTCGACTACTCGTACAGTGAACTGCAAGCACTCATCCCGAGGCTGAAAGAGAAAACC
GGGGAACGCCGTTCGTTAACTGCGACCGCGCTCCAGTTTTGCTTGTATGATCCGGTCGTTGCTGCCGTCATTCCAGGTGC
GAGCCGGCTTGAGCAGCTGGCGGAAAACATCGCTGCCGCATCCGCGCTGCCGCTTGACGCTGACGAATACAAATGGTTAA
AACAAGCGACGAAGCGCTCGGTGTACGAAATGCACCGATAA

Upstream 100 bases:

>100_bases
TCTCCCCTATCCATTGATAAATTCTTTTCCATTGTACTACATATTTGGCCATTTTTTCGCCCCTGTTGTACAATGATCAT
TAAGAAGGGAGCGTAACGCA

Downstream 100 bases:

>100_bases
GCACAGACGGCGACATAAGAAACCTCCCAACTTAGCTCACGGGAAACAGATTGGCATCACGTTGCCTGCAAAACGAATCG
TACCCCAGTACGAAATGTCC

Product: D-threo-aldose 1-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFVGKAVKGKRDQVIIATKVGNR
WRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHGGTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYV
KRSNIVSVMMQYSLLDRRPEEWFPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEKT
GERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKRSVYEMHR

Sequences:

>Translated_306_residues
MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFVGKAVKGKRDQVIIATKVGNR
WRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHGGTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYV
KRSNIVSVMMQYSLLDRRPEEWFPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEKT
GERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKRSVYEMHR
>Mature_306_residues
MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFVGKAVKGKRDQVIIATKVGNR
WRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHGGTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYV
KRSNIVSVMMQYSLLDRRPEEWFPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEKT
GERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKRSVYEMHR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223718702, Length=306, Percent_Identity=30.3921568627451, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=28.2539682539683, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI27436964, Length=313, Percent_Identity=28.7539936102236, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=28.7539936102236, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436962, Length=313, Percent_Identity=28.4345047923323, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI41327764, Length=302, Percent_Identity=30.1324503311258, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI41152114, Length=306, Percent_Identity=28.7581699346405, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=26.6881028938907, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI87081735, Length=305, Percent_Identity=34.4262295081967, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=32.5878594249201, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789199, Length=322, Percent_Identity=30.4347826086957, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789375, Length=322, Percent_Identity=29.1925465838509, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787674, Length=299, Percent_Identity=27.4247491638796, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788081, Length=210, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87082198, Length=205, Percent_Identity=28.2926829268293, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786400, Length=274, Percent_Identity=26.6423357664234, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=295, Percent_Identity=27.1186440677966, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=26.7647058823529, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646155, Length=221, Percent_Identity=34.3891402714932, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=32.1266968325792, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34685; Mature: 34685

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFV
CCCCCCCCHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHH
GKAVKGKRDQVIIATKVGNRWRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHG
HHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYVKRSNIVSVMMQYSLLDRRPE
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EWFPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEKT
HHHHHHHHCCCEEEECCCCHHCHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKRS
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VYEMHR
HHHHCC
>Mature Secondary Structure
MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFV
CCCCCCCCHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHH
GKAVKGKRDQVIIATKVGNRWRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHG
HHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYVKRSNIVSVMMQYSLLDRRPE
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EWFPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEKT
HHHHHHHHCCCEEEECCCCHHCHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKRS
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VYEMHR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]