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The map label for this gene is degA [H]

Identifier: 138895464

GI number: 138895464

Start: 1923236

End: 1924246

Strand: Reverse

Name: degA [H]

Synonym: GTNG_1812

Alternate gene names: 138895464

Gene position: 1924246-1923236 (Counterclockwise)

Preceding gene: 138895465

Following gene: 138895463

Centisome position: 54.2

GC content: 41.25

Gene sequence:

>1011_bases
ATGAGACCTACTATTTACGATGTAGCTGAACGAGCAGGTGTATCGATAGCGACCGTATCAAAAGTACTTAATAATACGGG
GAATATTAGTGATCGAACCAAAAAAAAGGTTATAAAGGTCATGCAGGAGCTTGGATACCACCCGAACAGTTTGGCTGCAG
CGTTAACCGGTAAAAAAACATTTACAATTGGTGTGTTAGTTCCTGATATCGCTAACCCATTTTTTGCTGAGGTCTCCCGG
GCATTAGAGAATTATGCCCGGGAAACCGGATATGCGATTATATTGTGCAGTACTGACTATCAGCTCGAACGGGAACAGTA
TTATCTTGATCTTCTTATGAAAAAACAGGTGGATGGCATTATCATTGCTACAGAACCAAAGGATCTAAATGCCTTCCAGA
CACTCCAATCAAGAAATATTCCATTTTTGATGTTTTCTATTGATCATCTCGCCTTATCTTCGCATGTAGTTACTACTGAT
GATATAAGGGGAGGGTATCTTGCCGGGCGTTATCTACTAGATAAAGGGCATCGCCGTTTGGCCATCATTGCAGAGTTAAA
TCGCCCGAGTGGACGCCTGAGATTGGAAGGGTTTAGAAGAGCTCTTTCTGATCATGGAATTGAATTGGATCAACGTTTCA
TTATTGACTCTATTTCTAAAATTGAAGATGCAAAGATAGCGTCACAAAAAATTCTTCATCTGCCGGAAAGACCGACAGCT
GTCTTTGCGACAACAGATTTAATTGCTGTGGTTTTTATGAACGAAGCTCGAAAGACAAATGTATCAGTTCCGGAAGATAT
TTCTGTCATTGGGTTTGATAATACGATCCATGCAGAAATTGCAGATCCCGGGTTAACGACGATTGCCCAGCCGATTGATG
AGTTGGCTCGCTATGCTATCTATAAGTTACTCGAGTCCATTGAAAACCCTCAAATCCCAAGTCATCGGATTATGCTGACA
CCATCTCTAATTGAACGGGAGTCAGTAAAGGATTTAAACGGTCATTGTTAG

Upstream 100 bases:

>100_bases
CACGAAAGACAACGCTCAAGAGAAATTAGAATTTCTCAAAACGATATCAAAATAGGTATATTTGGAAGGGAAAGGATTAT
CTAAGGGGTTTGAACATATT

Downstream 100 bases:

>100_bases
TACCATGAAAATAGCACCGATATGTATATTCGGTGTCTTTATTTTCACAAATAAGTAAAGCGCTTACCCTTTGTTCCCTC
CCTCGATCTGTTTAAAAGAA

Product: transcriptional regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRPTIYDVAERAGVSIATVSKVLNNTGNISDRTKKKVIKVMQELGYHPNSLAAALTGKKTFTIGVLVPDIANPFFAEVSR
ALENYARETGYAIILCSTDYQLEREQYYLDLLMKKQVDGIIIATEPKDLNAFQTLQSRNIPFLMFSIDHLALSSHVVTTD
DIRGGYLAGRYLLDKGHRRLAIIAELNRPSGRLRLEGFRRALSDHGIELDQRFIIDSISKIEDAKIASQKILHLPERPTA
VFATTDLIAVVFMNEARKTNVSVPEDISVIGFDNTIHAEIADPGLTTIAQPIDELARYAIYKLLESIENPQIPSHRIMLT
PSLIERESVKDLNGHC

Sequences:

>Translated_336_residues
MRPTIYDVAERAGVSIATVSKVLNNTGNISDRTKKKVIKVMQELGYHPNSLAAALTGKKTFTIGVLVPDIANPFFAEVSR
ALENYARETGYAIILCSTDYQLEREQYYLDLLMKKQVDGIIIATEPKDLNAFQTLQSRNIPFLMFSIDHLALSSHVVTTD
DIRGGYLAGRYLLDKGHRRLAIIAELNRPSGRLRLEGFRRALSDHGIELDQRFIIDSISKIEDAKIASQKILHLPERPTA
VFATTDLIAVVFMNEARKTNVSVPEDISVIGFDNTIHAEIADPGLTTIAQPIDELARYAIYKLLESIENPQIPSHRIMLT
PSLIERESVKDLNGHC
>Mature_336_residues
MRPTIYDVAERAGVSIATVSKVLNNTGNISDRTKKKVIKVMQELGYHPNSLAAALTGKKTFTIGVLVPDIANPFFAEVSR
ALENYARETGYAIILCSTDYQLEREQYYLDLLMKKQVDGIIIATEPKDLNAFQTLQSRNIPFLMFSIDHLALSSHVVTTD
DIRGGYLAGRYLLDKGHRRLAIIAELNRPSGRLRLEGFRRALSDHGIELDQRFIIDSISKIEDAKIASQKILHLPERPTA
VFATTDLIAVVFMNEARKTNVSVPEDISVIGFDNTIHAEIADPGLTTIAQPIDELARYAIYKLLESIENPQIPSHRIMLT
PSLIERESVKDLNGHC

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=36.4457831325301, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1790194, Length=327, Percent_Identity=36.085626911315, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=34.441087613293, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=31.1526479750779, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=29.5180722891566, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789202, Length=333, Percent_Identity=29.1291291291291, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=28.955223880597, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=28.955223880597, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI48994940, Length=311, Percent_Identity=25.4019292604502, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786268, Length=317, Percent_Identity=29.0220820189274, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787906, Length=332, Percent_Identity=25, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790715, Length=309, Percent_Identity=24.5954692556634, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789456, Length=310, Percent_Identity=24.5161290322581, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37527; Mature: 37527

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTIYDVAERAGVSIATVSKVLNNTGNISDRTKKKVIKVMQELGYHPNSLAAALTGKKT
CCCHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHEECCCCE
FTIGVLVPDIANPFFAEVSRALENYARETGYAIILCSTDYQLEREQYYLDLLMKKQVDGI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEE
IIATEPKDLNAFQTLQSRNIPFLMFSIDHLALSSHVVTTDDIRGGYLAGRYLLDKGHRRL
EEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCEE
AIIAELNRPSGRLRLEGFRRALSDHGIELDQRFIIDSISKIEDAKIASQKILHLPERPTA
EEEEECCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VFATTDLIAVVFMNEARKTNVSVPEDISVIGFDNTIHAEIADPGLTTIAQPIDELARYAI
EEEHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHH
YKLLESIENPQIPSHRIMLTPSLIERESVKDLNGHC
HHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRPTIYDVAERAGVSIATVSKVLNNTGNISDRTKKKVIKVMQELGYHPNSLAAALTGKKT
CCCHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHEECCCCE
FTIGVLVPDIANPFFAEVSRALENYARETGYAIILCSTDYQLEREQYYLDLLMKKQVDGI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEE
IIATEPKDLNAFQTLQSRNIPFLMFSIDHLALSSHVVTTDDIRGGYLAGRYLLDKGHRRL
EEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCEEECCCCCCCCCCHHHHHHCCCCEE
AIIAELNRPSGRLRLEGFRRALSDHGIELDQRFIIDSISKIEDAKIASQKILHLPERPTA
EEEEECCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VFATTDLIAVVFMNEARKTNVSVPEDISVIGFDNTIHAEIADPGLTTIAQPIDELARYAI
EEEHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHH
YKLLESIENPQIPSHRIMLTPSLIERESVKDLNGHC
HHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]