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The map label for this gene is fbaA [H]

Identifier: 138895457

GI number: 138895457

Start: 1914673

End: 1915560

Strand: Reverse

Name: fbaA [H]

Synonym: GTNG_1805

Alternate gene names: 138895457

Gene position: 1915560-1914673 (Counterclockwise)

Preceding gene: 138895458

Following gene: 138895456

Centisome position: 53.95

GC content: 47.75

Gene sequence:

>888_bases
ATGCCGCTTGTCTCAATGAAGGAAATGTTACAATGTGCTTTACAGGGAAACTATGCTGTCGGCCATTTTAACGTGAACAA
CTTAGAATTCGCCCAAGCCATTCTCCTAGGGGCCGAAGAAGAGGAAGCACCCGTCATTTTGGCTGTGAGTCCGGGATATA
TCGGGCATCTTGGTGGACTCCGGACGGCAGCGGCCATGGTTAAAGAACTCGTGAAAGAATACCGCATTACTGTACCTGTC
GCTCTCCATTTAGACCACGGCTCCTCCTATGAGCAATGCCTCGAAGCGATGGAAGCTGGGTTTACATCCGTGATGATTGA
TGCTTCCCATTTCCCTTTGGAAGAAAATATTTCGATGACAAAAAAAGTTGTTGAGGCGGCTCGGTTTTTTGGTGTCTCCG
TTGAAGCAGAGGTCGGAAGAATCGGAGGGCAAGAGGATGACGTAGTGGTCGATGAAGCGGAAGCGATGTACGCCATTCCG
GAAGAATGTGAGCGGTTAGTCAAAGAAACCGGAGTTGACTGCCTAGCACCGGCATTAGGTTCGGTTCACGGTCCGTATAA
AGGGAAACCGAAATTAGGATTTGCGCAAATGGAACAAATCCAGCGCTTAACTGGCGTGCCGCTTGTGCTGCATGGAGGAA
CAGGAATCCCCTTGGAGGATATTCGCAGAGCCATTTCGTTAGGAACAGCTAAAATTAACGTCAACACGGAAAATCAATTG
GCGTTTACTAGGGGAGTTCGTTCTTTACTCAATGAGAATAACGGCCTGTATGATCCGAGAAAATACCTTGGGGCAGGAAG
AGAAGAAGTAAAACAGACCGTAAGACAAAAAATTCGCGAATTCGGTTCGGTAGGGAAAGCGAAAGAAGGGGTGTTGTCTT
CATTGTAA

Upstream 100 bases:

>100_bases
AATGCTCACTGCTCGCTGGTAAGAGCGATGGAAAAACGATCAGGCGCCTTAGGGCGCTTGATGCTTTTTCACGAATGTGT
AAACAGAAAGGGGAATCGAA

Downstream 100 bases:

>100_bases
CGAGAATGATGCACAAGCTGTCGCGCCGGAAGCCAAGCGGTTCGAACAGGCGCAAAGCCCGCTGAAAAGGGGCCAAGCTT
CATGAGAAAATCACCAACTG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPLVSMKEMLQCALQGNYAVGHFNVNNLEFAQAILLGAEEEEAPVILAVSPGYIGHLGGLRTAAAMVKELVKEYRITVPV
ALHLDHGSSYEQCLEAMEAGFTSVMIDASHFPLEENISMTKKVVEAARFFGVSVEAEVGRIGGQEDDVVVDEAEAMYAIP
EECERLVKETGVDCLAPALGSVHGPYKGKPKLGFAQMEQIQRLTGVPLVLHGGTGIPLEDIRRAISLGTAKINVNTENQL
AFTRGVRSLLNENNGLYDPRKYLGAGREEVKQTVRQKIREFGSVGKAKEGVLSSL

Sequences:

>Translated_295_residues
MPLVSMKEMLQCALQGNYAVGHFNVNNLEFAQAILLGAEEEEAPVILAVSPGYIGHLGGLRTAAAMVKELVKEYRITVPV
ALHLDHGSSYEQCLEAMEAGFTSVMIDASHFPLEENISMTKKVVEAARFFGVSVEAEVGRIGGQEDDVVVDEAEAMYAIP
EECERLVKETGVDCLAPALGSVHGPYKGKPKLGFAQMEQIQRLTGVPLVLHGGTGIPLEDIRRAISLGTAKINVNTENQL
AFTRGVRSLLNENNGLYDPRKYLGAGREEVKQTVRQKIREFGSVGKAKEGVLSSL
>Mature_294_residues
PLVSMKEMLQCALQGNYAVGHFNVNNLEFAQAILLGAEEEEAPVILAVSPGYIGHLGGLRTAAAMVKELVKEYRITVPVA
LHLDHGSSYEQCLEAMEAGFTSVMIDASHFPLEENISMTKKVVEAARFFGVSVEAEVGRIGGQEDDVVVDEAEAMYAIPE
ECERLVKETGVDCLAPALGSVHGPYKGKPKLGFAQMEQIQRLTGVPLVLHGGTGIPLEDIRRAISLGTAKINVNTENQLA
FTRGVRSLLNENNGLYDPRKYLGAGREEVKQTVRQKIREFGSVGKAKEGVLSSL

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=287, Percent_Identity=42.1602787456446, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=42.6573426573427, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1788072, Length=288, Percent_Identity=37.8472222222222, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1789293, Length=342, Percent_Identity=27.4853801169591, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322790, Length=334, Percent_Identity=26.0479041916168, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 31951; Mature: 31820

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMKEMLQCALQGNYAVGHFNVNNLEFAQAILLGAEEEEAPVILAVSPGYIGHLGGL
CCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
RTAAAMVKELVKEYRITVPVALHLDHGSSYEQCLEAMEAGFTSVMIDASHFPLEENISMT
HHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHH
KKVVEAARFFGVSVEAEVGRIGGQEDDVVVDEAEAMYAIPEECERLVKETGVDCLAPALG
HHHHHHHHHHCCCEEHHHHHCCCCCCCEEEECCHHHHCCHHHHHHHHHHCCHHHHHHHHH
SVHGPYKGKPKLGFAQMEQIQRLTGVPLVLHGGTGIPLEDIRRAISLGTAKINVNTENQL
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCEEEEECCCHHH
AFTRGVRSLLNENNGLYDPRKYLGAGREEVKQTVRQKIREFGSVGKAKEGVLSSL
HHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
PLVSMKEMLQCALQGNYAVGHFNVNNLEFAQAILLGAEEEEAPVILAVSPGYIGHLGGL
CCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHH
RTAAAMVKELVKEYRITVPVALHLDHGSSYEQCLEAMEAGFTSVMIDASHFPLEENISMT
HHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHH
KKVVEAARFFGVSVEAEVGRIGGQEDDVVVDEAEAMYAIPEECERLVKETGVDCLAPALG
HHHHHHHHHHCCCEEHHHHHCCCCCCCEEEECCHHHHCCHHHHHHHHHHCCHHHHHHHHH
SVHGPYKGKPKLGFAQMEQIQRLTGVPLVLHGGTGIPLEDIRRAISLGTAKINVNTENQL
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCEEEEECCCHHH
AFTRGVRSLLNENNGLYDPRKYLGAGREEVKQTVRQKIREFGSVGKAKEGVLSSL
HHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA