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The map label for this gene is kdgK [H]

Identifier: 138895424

GI number: 138895424

Start: 1869455

End: 1870408

Strand: Reverse

Name: kdgK [H]

Synonym: GTNG_1768

Alternate gene names: 138895424

Gene position: 1870408-1869455 (Counterclockwise)

Preceding gene: 138895425

Following gene: 138895423

Centisome position: 52.68

GC content: 51.36

Gene sequence:

>954_bases
ATGGACGTCGTCACGATTGGGGAATCGATGGCCGTATTGACACCGACAAGCGGTGGATTCATGAGGCAGGCGATCACCTT
TACAAGACAAATCGGCGGTGCGGAATCGAATGTGGCTGTCGGCCTTGCCCGCTTAGGCCATCGAGTCGGTTGGATTAGCA
AAGTGGGAGACGATGAGTTTGGGAAAGCGATTTTGTCTTTTCTGCAAGGTGAAGGCGTGGATGTCAGCCAGGTGAAAGCC
GATCTGGAAGCGCCAACCGGTATTTACTTTAAGGAAAAAAGACGTCCAGGCGATACTAGGGTGTATTACTATCGCCGGGG
ATCGGCGGCAAGCCGGTTGACGCCTAATGATTTGGATGAGGAATATATCGCTAAGGCGAAGTATTTGCATATTACCGGGA
TTACTCCAGCGCTAAGCAGGAGCTGCCAAGAAACGATTTTGGCGGCAATTGCCATGGCTCGCCGTCACGGAGTGAAAATT
GTCTTTGATCCGAATTTGCGCTTGAAGCTGTGGCGCGAAGCAAATGAAGCGAGAGAGATGCTTCTTCGTATTGCTGTTCA
ATCGGATATCGTTCTCCCTGGGGTTAGTGAAGCTGCGTTTTTGTTCGGTGATCGATCGATTGAAGAGTGGGGGAAACGGT
TGCTCGATGCTGGCGCATCGCTTGTTGTCATTAAACTTGGTGCAAGCGGAGCACATTATTTTACAAGCGGTGCAAATGAA
TATGTTCCTGGATTTCCTGTTGAGCAGATTATTGATCCGGTCGGTGCTGGTGACGGATTTGCAGCTGGATTGTTATCTGG
ATTGCTTGATGGACTCAGTCTGACCGAGGCTGTCCGACGGGGGAATGCAGTCGGGGCGCTAGTAACGATGGTTGAAGGCG
ATGTGGACGGGATGCCGGAGAGGGATGAAGTAAAGCGGCTCATTGACCGCCAAGGGGAAGATGTCACCCGGTAA

Upstream 100 bases:

>100_bases
GGGATGAAACAAGCACCTATATCGGCTTAGATGATAGTGAAATGACATCGTATTCTTCATCTGAATGATATACAACAAAT
CGTTGCAGCGGAGGGATGAG

Downstream 100 bases:

>100_bases
GAAGGAGGAAGATCTTTATGGATGTATTGACAACGATCAAAAAAATTGGCATCGTGCCTGTTGTCCGTGGCGCGACAGTG
GACAATATTCTCCCAATTGC

Product: 2-keto-3-deoxy-gluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDVVTIGESMAVLTPTSGGFMRQAITFTRQIGGAESNVAVGLARLGHRVGWISKVGDDEFGKAILSFLQGEGVDVSQVKA
DLEAPTGIYFKEKRRPGDTRVYYYRRGSAASRLTPNDLDEEYIAKAKYLHITGITPALSRSCQETILAAIAMARRHGVKI
VFDPNLRLKLWREANEAREMLLRIAVQSDIVLPGVSEAAFLFGDRSIEEWGKRLLDAGASLVVIKLGASGAHYFTSGANE
YVPGFPVEQIIDPVGAGDGFAAGLLSGLLDGLSLTEAVRRGNAVGALVTMVEGDVDGMPERDEVKRLIDRQGEDVTR

Sequences:

>Translated_317_residues
MDVVTIGESMAVLTPTSGGFMRQAITFTRQIGGAESNVAVGLARLGHRVGWISKVGDDEFGKAILSFLQGEGVDVSQVKA
DLEAPTGIYFKEKRRPGDTRVYYYRRGSAASRLTPNDLDEEYIAKAKYLHITGITPALSRSCQETILAAIAMARRHGVKI
VFDPNLRLKLWREANEAREMLLRIAVQSDIVLPGVSEAAFLFGDRSIEEWGKRLLDAGASLVVIKLGASGAHYFTSGANE
YVPGFPVEQIIDPVGAGDGFAAGLLSGLLDGLSLTEAVRRGNAVGALVTMVEGDVDGMPERDEVKRLIDRQGEDVTR
>Mature_317_residues
MDVVTIGESMAVLTPTSGGFMRQAITFTRQIGGAESNVAVGLARLGHRVGWISKVGDDEFGKAILSFLQGEGVDVSQVKA
DLEAPTGIYFKEKRRPGDTRVYYYRRGSAASRLTPNDLDEEYIAKAKYLHITGITPALSRSCQETILAAIAMARRHGVKI
VFDPNLRLKLWREANEAREMLLRIAVQSDIVLPGVSEAAFLFGDRSIEEWGKRLLDAGASLVVIKLGASGAHYFTSGANE
YVPGFPVEQIIDPVGAGDGFAAGLLSGLLDGLSLTEAVRRGNAVGALVTMVEGDVDGMPERDEVKRLIDRQGEDVTR

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=288, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082281, Length=311, Percent_Identity=28.6173633440514, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87081971, Length=321, Percent_Identity=28.3489096573209, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790193, Length=285, Percent_Identity=27.0175438596491, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788417, Length=280, Percent_Identity=27.5, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 34239; Mature: 34239

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVTIGESMAVLTPTSGGFMRQAITFTRQIGGAESNVAVGLARLGHRVGWISKVGDDEF
CCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
GKAILSFLQGEGVDVSQVKADLEAPTGIYFKEKRRPGDTRVYYYRRGSAASRLTPNDLDE
HHHHHHHHCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCH
EYIAKAKYLHITGITPALSRSCQETILAAIAMARRHGVKIVFDPNLRLKLWREANEAREM
HHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEHHHHHHHHHH
LLRIAVQSDIVLPGVSEAAFLFGDRSIEEWGKRLLDAGASLVVIKLGASGAHYFTSGANE
HHHHHHHCCEECCCCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCC
YVPGFPVEQIIDPVGAGDGFAAGLLSGLLDGLSLTEAVRRGNAVGALVTMVEGDVDGMPE
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCC
RDEVKRLIDRQGEDVTR
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDVVTIGESMAVLTPTSGGFMRQAITFTRQIGGAESNVAVGLARLGHRVGWISKVGDDEF
CCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
GKAILSFLQGEGVDVSQVKADLEAPTGIYFKEKRRPGDTRVYYYRRGSAASRLTPNDLDE
HHHHHHHHCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCH
EYIAKAKYLHITGITPALSRSCQETILAAIAMARRHGVKIVFDPNLRLKLWREANEAREM
HHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEHHHHHHHHHH
LLRIAVQSDIVLPGVSEAAFLFGDRSIEEWGKRLLDAGASLVVIKLGASGAHYFTSGANE
HHHHHHHCCEECCCCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCC
YVPGFPVEQIIDPVGAGDGFAAGLLSGLLDGLSLTEAVRRGNAVGALVTMVEGDVDGMPE
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCC
RDEVKRLIDRQGEDVTR
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]