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The map label for this gene is ina [H]

Identifier: 138895377

GI number: 138895377

Start: 1818638

End: 1820893

Strand: Reverse

Name: ina [H]

Synonym: GTNG_1721

Alternate gene names: 138895377

Gene position: 1820893-1818638 (Counterclockwise)

Preceding gene: 138895380

Following gene: 138895376

Centisome position: 51.29

GC content: 52.48

Gene sequence:

>2256_bases
GTGAAGCAAGGCGGGCCAGTCGATTTTGCCATTGCCAACGAAGACAAACTGACGGAAATGTTAAAACGAAACGGAACGCT
TCGCTCCAATGCGACTCCCGCTGAGGCAGAACAGGAGGTGCGCAAGTATTTGCGGCAAAAGGCAGCTCACATGCCGCGGG
CAAAGGGGGAACTGTACGAAAAAGAGAAGAAGCGCACCGAAGTGTTGCGACAAAAATTGCGGACAAACGGCGTGCTGAAT
GGGAAAGGGAAAAAACTAGGGCAATCAAAGACAGCTTCCGTGCCGCCCGTCCATCCGGAGCCGTGGAACGGAGGCAAACG
GGTCGATCGAGTGCTCGTCTTGCTCATTGAATATCCGGATTTTCCGCACAACAGCATTCAACCAAATGAAACAGACATGT
ATTACAAAGATTATACACGCGAGCACTATGAAGACATGATTTTTGGCGGCGATGATGGCTATTACGAAGGGCCAAACGGC
GAAAAACTCATGTCGGTGAAACAATATTACGAAGAACAATCGGGAGGCAGCTATTCGATCGAAGGAAAGGTGGCTGGTTG
GTACAAAGCCAAACATCCTGCCAAATATTACGGCGGCAACGTGCCGGCGCCGGACGGGAACGATGCCAACCCGCGTGAGC
TTGTGCGCGAAGCGCTGATGGCGGCAGCCAACGATCCGACCATTGATTTAAGCGAGTTTGACCAAGAGGATCGGTATGAT
TTGGACGGTGACGGCAATTACCGCGAGCCAGACGGCTTGATCGACCATTTGATGATCATCCACTCGAGCGTCGGTGAAGA
GGCGGGCGGCGGTTCGCTCGGCGGTGATGCTATTTGGTCGCACCGTTGGAATTTAGGATCGGTATACCCGATTCCGAACA
CGACGACTGAGGTGCCGTATTGGAATGGTCAGCTGGCTGCTTATGACTATACGGTCGAGCCGGCCGACGGGGCTGCGGGG
GTGTTCGCCCACGAATACGGTCACGATTTAGGGTTGCCGGATGAATATGATACCATTTACTCCGGCTTGGGCGAACCGAT
TGCGTATTGGTCGATCATGTCGAGCGGCAGCTGGGCGGGGCGCATTCCGGGCACGGAGCCGACCGGTTTCAGCGCCTGGG
CAAAACAGTTTTTGCAGTCAACCATGCCGGGAAGCAACTGGCTGCACGGAACGACCGTGGAATGGGATGAAGTGACGAAA
CAAGGAGTAGAGGTTGTATTGGATGAAGCCAATACGAAAGGAACAAACAACGATGCCGTGCGCATCAACTTGCCGGATAA
GAAAACTACCATCGTTTCTCCAGCCAGCGGCGCCTATGCATACTTCTCCGGCAAAGGGAATAATTTGAACAGCTCTATGT
CCACCACAGTTGATTTGACAGGCGCATCGCAAGCAGTATTGACGTTTGATGCATGGTATGCGATTGAGAAAGATTGGGAT
TACGGGGTGGTTGAAGTGAAGGAACAAAGTTTGAATCAATGGGTAACGGTTTCAGGAAATATTACAACGACCGACGACCC
AAATGGGCAAAACCCAGGCAACGGCATTACCGGCACATCGGACGGTTGGGTGAAAGCCGAGTTTGACTTGTCGGCGTACG
CAGGCCAAACGATTGAGCTGCGTTTCCGTTACGTGACCGATGCGTATGTATCGGAAGCTGGCTGGTATATTGATAATGTT
CAAGTGATGGCAGACAAAACAGCCATACTTACGGACGGAGCGGAAAACGAGAGCATTTTCGTGTTGGATGGTTTTGCGAA
AAGCGACGGTACGCTGCGTTCGAAGCATTACTATTTGTTGGAATGGCGCAACCACCGTGGCGTTGATAAAGGACTGGCGC
ATATTTTGCGCGGCGATCAATTGCTGTCGTACGACCCGGGCCTTGTTGTTTGGTATGTGGATGAGTCATATGACAACAAC
TGGACAGGCGTCCATCCGGGTGAAGGGTTCCTTGGTGTCGTGGATGCTAATCAGCACACGTTGAAATGGTCAGGCAATAC
GGTGGCTTCCACGCGCTATCAAGTGCATGATGCGGCATTTAGTTTGCAAAAAGGCGTGCCGTTTCGCGTTGAAATTGACG
GATCGAAACTGATCGACAACGACACGTCGCCGTTGCCGGTTTTTGATGACAGCCGGTCGTACCGTAACAAAGGAGCGGTT
GATGCGGGGCGGAACGTGCCGACGTACGGTTTAAAAATTCGCGTCGTCGGTGAAAGTGCCGACCGCACTGCGGGACGTGT
GTTGATTTACCGCTAA

Upstream 100 bases:

>100_bases
ATCGATTCTTTCATTGACAGCGGCGCTGTCGCTCGGAATAGGGCTGTGGGCGGCGCCGGCAAAAGCGCCGCAAGCAGCCA
ACACCGCGGCGATCCCGGCG

Downstream 100 bases:

>100_bases
TCGAGCCAAAAGGGTGTTCCAAAATGGGCACCCTTTTTGTATATACGCACGGAACCATTCAAACAGTTTATCTCTTGTGT
CTTTCTTGAAGACAGAAGAT

Product: secreted protease metal-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MKQGGPVDFAIANEDKLTEMLKRNGTLRSNATPAEAEQEVRKYLRQKAAHMPRAKGELYEKEKKRTEVLRQKLRTNGVLN
GKGKKLGQSKTASVPPVHPEPWNGGKRVDRVLVLLIEYPDFPHNSIQPNETDMYYKDYTREHYEDMIFGGDDGYYEGPNG
EKLMSVKQYYEEQSGGSYSIEGKVAGWYKAKHPAKYYGGNVPAPDGNDANPRELVREALMAAANDPTIDLSEFDQEDRYD
LDGDGNYREPDGLIDHLMIIHSSVGEEAGGGSLGGDAIWSHRWNLGSVYPIPNTTTEVPYWNGQLAAYDYTVEPADGAAG
VFAHEYGHDLGLPDEYDTIYSGLGEPIAYWSIMSSGSWAGRIPGTEPTGFSAWAKQFLQSTMPGSNWLHGTTVEWDEVTK
QGVEVVLDEANTKGTNNDAVRINLPDKKTTIVSPASGAYAYFSGKGNNLNSSMSTTVDLTGASQAVLTFDAWYAIEKDWD
YGVVEVKEQSLNQWVTVSGNITTTDDPNGQNPGNGITGTSDGWVKAEFDLSAYAGQTIELRFRYVTDAYVSEAGWYIDNV
QVMADKTAILTDGAENESIFVLDGFAKSDGTLRSKHYYLLEWRNHRGVDKGLAHILRGDQLLSYDPGLVVWYVDESYDNN
WTGVHPGEGFLGVVDANQHTLKWSGNTVASTRYQVHDAAFSLQKGVPFRVEIDGSKLIDNDTSPLPVFDDSRSYRNKGAV
DAGRNVPTYGLKIRVVGESADRTAGRVLIYR

Sequences:

>Translated_751_residues
MKQGGPVDFAIANEDKLTEMLKRNGTLRSNATPAEAEQEVRKYLRQKAAHMPRAKGELYEKEKKRTEVLRQKLRTNGVLN
GKGKKLGQSKTASVPPVHPEPWNGGKRVDRVLVLLIEYPDFPHNSIQPNETDMYYKDYTREHYEDMIFGGDDGYYEGPNG
EKLMSVKQYYEEQSGGSYSIEGKVAGWYKAKHPAKYYGGNVPAPDGNDANPRELVREALMAAANDPTIDLSEFDQEDRYD
LDGDGNYREPDGLIDHLMIIHSSVGEEAGGGSLGGDAIWSHRWNLGSVYPIPNTTTEVPYWNGQLAAYDYTVEPADGAAG
VFAHEYGHDLGLPDEYDTIYSGLGEPIAYWSIMSSGSWAGRIPGTEPTGFSAWAKQFLQSTMPGSNWLHGTTVEWDEVTK
QGVEVVLDEANTKGTNNDAVRINLPDKKTTIVSPASGAYAYFSGKGNNLNSSMSTTVDLTGASQAVLTFDAWYAIEKDWD
YGVVEVKEQSLNQWVTVSGNITTTDDPNGQNPGNGITGTSDGWVKAEFDLSAYAGQTIELRFRYVTDAYVSEAGWYIDNV
QVMADKTAILTDGAENESIFVLDGFAKSDGTLRSKHYYLLEWRNHRGVDKGLAHILRGDQLLSYDPGLVVWYVDESYDNN
WTGVHPGEGFLGVVDANQHTLKWSGNTVASTRYQVHDAAFSLQKGVPFRVEIDGSKLIDNDTSPLPVFDDSRSYRNKGAV
DAGRNVPTYGLKIRVVGESADRTAGRVLIYR
>Mature_751_residues
MKQGGPVDFAIANEDKLTEMLKRNGTLRSNATPAEAEQEVRKYLRQKAAHMPRAKGELYEKEKKRTEVLRQKLRTNGVLN
GKGKKLGQSKTASVPPVHPEPWNGGKRVDRVLVLLIEYPDFPHNSIQPNETDMYYKDYTREHYEDMIFGGDDGYYEGPNG
EKLMSVKQYYEEQSGGSYSIEGKVAGWYKAKHPAKYYGGNVPAPDGNDANPRELVREALMAAANDPTIDLSEFDQEDRYD
LDGDGNYREPDGLIDHLMIIHSSVGEEAGGGSLGGDAIWSHRWNLGSVYPIPNTTTEVPYWNGQLAAYDYTVEPADGAAG
VFAHEYGHDLGLPDEYDTIYSGLGEPIAYWSIMSSGSWAGRIPGTEPTGFSAWAKQFLQSTMPGSNWLHGTTVEWDEVTK
QGVEVVLDEANTKGTNNDAVRINLPDKKTTIVSPASGAYAYFSGKGNNLNSSMSTTVDLTGASQAVLTFDAWYAIEKDWD
YGVVEVKEQSLNQWVTVSGNITTTDDPNGQNPGNGITGTSDGWVKAEFDLSAYAGQTIELRFRYVTDAYVSEAGWYIDNV
QVMADKTAILTDGAENESIFVLDGFAKSDGTLRSKHYYLLEWRNHRGVDKGLAHILRGDQLLSYDPGLVVWYVDESYDNN
WTGVHPGEGFLGVVDANQHTLKWSGNTVASTRYQVHDAAFSLQKGVPFRVEIDGSKLIDNDTSPLPVFDDSRSYRNKGAV
DAGRNVPTYGLKIRVVGESADRTAGRVLIYR

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 83028; Mature: 83028

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQGGPVDFAIANEDKLTEMLKRNGTLRSNATPAEAEQEVRKYLRQKAAHMPRAKGELYE
CCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
KEKKRTEVLRQKLRTNGVLNGKGKKLGQSKTASVPPVHPEPWNGGKRVDRVLVLLIEYPD
HHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEECCC
FPHNSIQPNETDMYYKDYTREHYEDMIFGGDDGYYEGPNGEKLMSVKQYYEEQSGGSYSI
CCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCEECCCCHHHHHHHHHHHHCCCCCEEE
EGKVAGWYKAKHPAKYYGGNVPAPDGNDANPRELVREALMAAANDPTIDLSEFDQEDRYD
ECEEEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHCCCCCCCC
LDGDGNYREPDGLIDHLMIIHSSVGEEAGGGSLGGDAIWSHRWNLGSVYPIPNTTTEVPY
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCC
WNGQLAAYDYTVEPADGAAGVFAHEYGHDLGLPDEYDTIYSGLGEPIAYWSIMSSGSWAG
CCCEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCC
RIPGTEPTGFSAWAKQFLQSTMPGSNWLHGTTVEWDEVTKQGVEVVLDEANTKGTNNDAV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCEE
RINLPDKKTTIVSPASGAYAYFSGKGNNLNSSMSTTVDLTGASQAVLTFDAWYAIEKDWD
EEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEEEEEEEEEECCCC
YGVVEVKEQSLNQWVTVSGNITTTDDPNGQNPGNGITGTSDGWVKAEFDLSAYAGQTIEL
CCEEEEECCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCEEEE
RFRYVTDAYVSEAGWYIDNVQVMADKTAILTDGAENESIFVLDGFAKSDGTLRSKHYYLL
EEEEEEHHHHHHCCCEEECEEEEECCEEEEECCCCCCEEEEEECCCCCCCCEECCEEEEE
EWRNHRGVDKGLAHILRGDQLLSYDPGLVVWYVDESYDNNWTGVHPGEGFLGVVDANQHT
EECCCCCHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCEE
LKWSGNTVASTRYQVHDAAFSLQKGVPFRVEIDGSKLIDNDTSPLPVFDDSRSYRNKGAV
EEECCCEEECCEEEEHHHHHHHHCCCCEEEEECCCEEECCCCCCCCEECCCHHHCCCCCC
DAGRNVPTYGLKIRVVGESADRTAGRVLIYR
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEC
>Mature Secondary Structure
MKQGGPVDFAIANEDKLTEMLKRNGTLRSNATPAEAEQEVRKYLRQKAAHMPRAKGELYE
CCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
KEKKRTEVLRQKLRTNGVLNGKGKKLGQSKTASVPPVHPEPWNGGKRVDRVLVLLIEYPD
HHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEECCC
FPHNSIQPNETDMYYKDYTREHYEDMIFGGDDGYYEGPNGEKLMSVKQYYEEQSGGSYSI
CCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCEECCCCHHHHHHHHHHHHCCCCCEEE
EGKVAGWYKAKHPAKYYGGNVPAPDGNDANPRELVREALMAAANDPTIDLSEFDQEDRYD
ECEEEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHCCCCCCCC
LDGDGNYREPDGLIDHLMIIHSSVGEEAGGGSLGGDAIWSHRWNLGSVYPIPNTTTEVPY
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCC
WNGQLAAYDYTVEPADGAAGVFAHEYGHDLGLPDEYDTIYSGLGEPIAYWSIMSSGSWAG
CCCEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCC
RIPGTEPTGFSAWAKQFLQSTMPGSNWLHGTTVEWDEVTKQGVEVVLDEANTKGTNNDAV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCEE
RINLPDKKTTIVSPASGAYAYFSGKGNNLNSSMSTTVDLTGASQAVLTFDAWYAIEKDWD
EEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEEEEEEEEEECCCC
YGVVEVKEQSLNQWVTVSGNITTTDDPNGQNPGNGITGTSDGWVKAEFDLSAYAGQTIEL
CCEEEEECCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCEEEE
RFRYVTDAYVSEAGWYIDNVQVMADKTAILTDGAENESIFVLDGFAKSDGTLRSKHYYLL
EEEEEEHHHHHHCCCEEECEEEEECCEEEEECCCCCCEEEEEECCCCCCCCEECCEEEEE
EWRNHRGVDKGLAHILRGDQLLSYDPGLVVWYVDESYDNNWTGVHPGEGFLGVVDANQHT
EECCCCCHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCEE
LKWSGNTVASTRYQVHDAAFSLQKGVPFRVEIDGSKLIDNDTSPLPVFDDSRSYRNKGAV
EEECCCEEECCEEEEHHHHHHHHCCCCEEEEECCCEEECCCCCCCCEECCCHHHCCCCCC
DAGRNVPTYGLKIRVVGESADRTAGRVLIYR
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]