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The map label for this gene is hemD [H]

Identifier: 138895375

GI number: 138895375

Start: 1817171

End: 1817965

Strand: Reverse

Name: hemD [H]

Synonym: GTNG_1719

Alternate gene names: 138895375

Gene position: 1817965-1817171 (Counterclockwise)

Preceding gene: 138895376

Following gene: 138895374

Centisome position: 51.21

GC content: 53.84

Gene sequence:

>795_bases
ATGCGCGGCAAACGGGTCGCCTTATGCGCTTCGCGCAAGTTAGACGAAATGACAACACTCATTGAAAAGCAAGGAGGAAC
GGCCGTCATCCGCCCGGCGCAAGGGACGGTTTTTTTAAAAGGAAGTGAACTCAGTGAGGAAATGCGCGCGATCATTATGA
TGCGGCCGGACTGGATAGTGTTTACAACGGGCATTGGGGTTGAAGCGCTCTGGAAAACGGCTGAAAGGGAAGGGATCGCG
GTTGAGTGGAAGCGCGTGATCGAGAATGCTGATATCGCTGCGCGCGGCTATAAAACGGTGGCGGCATTGAAAAACATCGG
CGTTATCCCAACAGCGGTGAGCGAAGACGGGACGACGAAGGGATTGATTTCCGCCCTTAACGCGTATGACTTTGCCGGCA
AGAGCGTCGTCGCGCAGCTATACGGTGATACGGCGCCAGTCTTGAAGCAATTTTTCCTTACGCGCGGTGCGTCTTACACA
GAGCTATTCCCGTATCGGCATGTCGCCCCAGATCACGAGATGCTGGAGATGCTATACAACGAAGTCGTCGGGCGCGAAAT
TGATGCGGTCTGTTTTACATCGGCGATACAAGTCCGCTTTTTCTTTTCGTTTGCCCGGGAGAAACAAGATATCACTCCGC
TGCTTGAGGCGTTCTGCACCGATGTCGTCGCCTGTGCTGTCGGGAAAGTGACGAAAGAAGCGCTGGAAGAGGAAGGAGTC
AGCCGCGTCATCACCCCTGAACATGAGCGGATGGGAGCGATGATCGTGACGCTTGCCCGTTATTTTCAACAATAA

Upstream 100 bases:

>100_bases
GGTGACACGCGCCTTTTAGGGTGCGTGTTTTTTCATTGCCTAGGCGGGGGCGATCTTTTAGAATGGAAAGGACGAATGAT
CGACGACGGGAGGGAAACGA

Downstream 100 bases:

>100_bases
GCCCCGTTGGGGCTTTTTGTTTTATATCAATTGTCCCATCTGTTATATAAGAAGTCATCTTGTTATTCACTGTTTTATAT
TACGTGTTTCACCAAAATCT

Product: uroporphyrinogen-III synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MRGKRVALCASRKLDEMTTLIEKQGGTAVIRPAQGTVFLKGSELSEEMRAIIMMRPDWIVFTTGIGVEALWKTAEREGIA
VEWKRVIENADIAARGYKTVAALKNIGVIPTAVSEDGTTKGLISALNAYDFAGKSVVAQLYGDTAPVLKQFFLTRGASYT
ELFPYRHVAPDHEMLEMLYNEVVGREIDAVCFTSAIQVRFFFSFAREKQDITPLLEAFCTDVVACAVGKVTKEALEEEGV
SRVITPEHERMGAMIVTLARYFQQ

Sequences:

>Translated_264_residues
MRGKRVALCASRKLDEMTTLIEKQGGTAVIRPAQGTVFLKGSELSEEMRAIIMMRPDWIVFTTGIGVEALWKTAEREGIA
VEWKRVIENADIAARGYKTVAALKNIGVIPTAVSEDGTTKGLISALNAYDFAGKSVVAQLYGDTAPVLKQFFLTRGASYT
ELFPYRHVAPDHEMLEMLYNEVVGREIDAVCFTSAIQVRFFFSFAREKQDITPLLEAFCTDVVACAVGKVTKEALEEEGV
SRVITPEHERMGAMIVTLARYFQQ
>Mature_264_residues
MRGKRVALCASRKLDEMTTLIEKQGGTAVIRPAQGTVFLKGSELSEEMRAIIMMRPDWIVFTTGIGVEALWKTAEREGIA
VEWKRVIENADIAARGYKTVAALKNIGVIPTAVSEDGTTKGLISALNAYDFAGKSVVAQLYGDTAPVLKQFFLTRGASYT
ELFPYRHVAPDHEMLEMLYNEVVGREIDAVCFTSAIQVRFFFSFAREKQDITPLLEAFCTDVVACAVGKVTKEALEEEGV
SRVITPEHERMGAMIVTLARYFQQ

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003754 [H]

Pfam domain/function: PF02602 HEM4 [H]

EC number: NA

Molecular weight: Translated: 29256; Mature: 29256

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKRVALCASRKLDEMTTLIEKQGGTAVIRPAQGTVFLKGSELSEEMRAIIMMRPDWIV
CCCCEEEHHHHCCHHHHHHHHHHCCCCEEEECCCCEEEEECCHHHHHHHHHEEECCCEEE
FTTGIGVEALWKTAEREGIAVEWKRVIENADIAARGYKTVAALKNIGVIPTAVSEDGTTK
EECCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
GLISALNAYDFAGKSVVAQLYGDTAPVLKQFFLTRGASYTELFPYRHVAPDHEMLEMLYN
HHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHH
EVVGREIDAVCFTSAIQVRFFFSFAREKQDITPLLEAFCTDVVACAVGKVTKEALEEEGV
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRVITPEHERMGAMIVTLARYFQQ
CCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGKRVALCASRKLDEMTTLIEKQGGTAVIRPAQGTVFLKGSELSEEMRAIIMMRPDWIV
CCCCEEEHHHHCCHHHHHHHHHHCCCCEEEECCCCEEEEECCHHHHHHHHHEEECCCEEE
FTTGIGVEALWKTAEREGIAVEWKRVIENADIAARGYKTVAALKNIGVIPTAVSEDGTTK
EECCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
GLISALNAYDFAGKSVVAQLYGDTAPVLKQFFLTRGASYTELFPYRHVAPDHEMLEMLYN
HHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHH
EVVGREIDAVCFTSAIQVRFFFSFAREKQDITPLLEAFCTDVVACAVGKVTKEALEEEGV
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRVITPEHERMGAMIVTLARYFQQ
CCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]