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The map label for this gene is cobT [H]

Identifier: 138895339

GI number: 138895339

Start: 1772449

End: 1773507

Strand: Reverse

Name: cobT [H]

Synonym: GTNG_1683

Alternate gene names: 138895339

Gene position: 1773507-1772449 (Counterclockwise)

Preceding gene: 138895340

Following gene: 138895338

Centisome position: 49.95

GC content: 58.55

Gene sequence:

>1059_bases
GTGATGAACAGTTCGATTCCACCGTTTTGCCACGAAATGGTCGAGGAAGCGCGCGCTTATCTTGATCAATTGACGAAGCC
GCCCGGCAGCCTGGGACGATTGGAAGAAGTGGCGGTTGAGCTTGCTGGTATGACGGGAGAGCTGCACCCGCGCGTCACGC
CGCCGGGTGTTTTAGTGTTTGCGGCTGATCATGGCATCGCGGAAGAAGGGGTGTCTGCCTATCCAGCCGAAGTGACGGCG
CAGATGGTGTATAACTTTGCCAATGGCGGGGCGGCGATCAACGTCTTTAGCCGTCGAATCGATGCGCTTCTTGAGATCGT
CGACGTCGGGGTGGCCGTGCCGATTGAGGACGAACGGGTCATTGTGAAAAAGGTTCGTCACGGAACCGGCAATTTTGCCA
AAACGGAAGCGATGACGCCCGAAGAAGCCGAACAAGCGCTTCACGTTGGCTATGAGCGAGCGGCACGCATCATCGGACAG
GGTGCCCGTACGTTCATTGCTGGTGAGATGGGAATCGGCAATACGACGGCAGCCAGTGCCTTATTAGCCACGTTGACCGA
TGAACCGCTCGAACACATTGTCGGCAAAGGAACCGGCATCGCTGCTGAAAGGCTGGTTCATAAACAGGAAGTCATCCGTC
AGGCGCTGGCGCTCCACCGGCCCGACCCGGCGAAGCCGATCGAGTGGCTGGCGAAAATCGGCGGACTTGAGATTGCCGCG
ATGGCCGGTGCCATGCTGGCAGCCGCCGAACGGCGCATCCCGATTTTGCTTGACGGTTTTATTTGCACGGTGGCTGCCCT
TGTGGCCCGCCAGTTTGCCGTGAACGTCACAGACTATATGATTGCCGGCCATCGTTCGCAAGAGCCGGGGCACAGTATAG
CCCTTCGTTTGCTAGAGAAGGATCCGCTTTTGGATCTCGGCATGCGCCTTGGCGAAGGAAGCGGCGCGGCGGTAGCGTTT
CCGCTCTTGATTTCAGCAATGGCGATGGTGAACGAAATGGCGACGTTCGCCTCGGCGGGCATTTCCACGGCCAATGCGAA
AGGGGAGAAGGGGCGATGA

Upstream 100 bases:

>100_bases
CAAGTAAATAGACTGTTCCTAGCTGTGGAAAATAGAGGGAGATCATAGATGGAAAGGGGGAAAGCACCTATTCCTGCCGG
ATGAGGGATATGGTGCATCT

Downstream 100 bases:

>100_bases
CCGTCGGCAAAGTGTATTTAGTCGGCGCTGGGCCGGGTGATGAAAAGCTCATCACGGTTTACGGCCGCGAATGCCTAGAA
CGGGCGGATGTCATTATTTA

Product: nicotinate-nucleotide- dimethylbenzimidazolephosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MMNSSIPPFCHEMVEEARAYLDQLTKPPGSLGRLEEVAVELAGMTGELHPRVTPPGVLVFAADHGIAEEGVSAYPAEVTA
QMVYNFANGGAAINVFSRRIDALLEIVDVGVAVPIEDERVIVKKVRHGTGNFAKTEAMTPEEAEQALHVGYERAARIIGQ
GARTFIAGEMGIGNTTAASALLATLTDEPLEHIVGKGTGIAAERLVHKQEVIRQALALHRPDPAKPIEWLAKIGGLEIAA
MAGAMLAAAERRIPILLDGFICTVAALVARQFAVNVTDYMIAGHRSQEPGHSIALRLLEKDPLLDLGMRLGEGSGAAVAF
PLLISAMAMVNEMATFASAGISTANAKGEKGR

Sequences:

>Translated_352_residues
MMNSSIPPFCHEMVEEARAYLDQLTKPPGSLGRLEEVAVELAGMTGELHPRVTPPGVLVFAADHGIAEEGVSAYPAEVTA
QMVYNFANGGAAINVFSRRIDALLEIVDVGVAVPIEDERVIVKKVRHGTGNFAKTEAMTPEEAEQALHVGYERAARIIGQ
GARTFIAGEMGIGNTTAASALLATLTDEPLEHIVGKGTGIAAERLVHKQEVIRQALALHRPDPAKPIEWLAKIGGLEIAA
MAGAMLAAAERRIPILLDGFICTVAALVARQFAVNVTDYMIAGHRSQEPGHSIALRLLEKDPLLDLGMRLGEGSGAAVAF
PLLISAMAMVNEMATFASAGISTANAKGEKGR
>Mature_352_residues
MMNSSIPPFCHEMVEEARAYLDQLTKPPGSLGRLEEVAVELAGMTGELHPRVTPPGVLVFAADHGIAEEGVSAYPAEVTA
QMVYNFANGGAAINVFSRRIDALLEIVDVGVAVPIEDERVIVKKVRHGTGNFAKTEAMTPEEAEQALHVGYERAARIIGQ
GARTFIAGEMGIGNTTAASALLATLTDEPLEHIVGKGTGIAAERLVHKQEVIRQALALHRPDPAKPIEWLAKIGGLEIAA
MAGAMLAAAERRIPILLDGFICTVAALVARQFAVNVTDYMIAGHRSQEPGHSIALRLLEKDPLLDLGMRLGEGSGAAVAF
PLLISAMAMVNEMATFASAGISTANAKGEKGR

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=339, Percent_Identity=38.6430678466077, Blast_Score=227, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37206; Mature: 37206

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNSSIPPFCHEMVEEARAYLDQLTKPPGSLGRLEEVAVELAGMTGELHPRVTPPGVLVF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
AADHGIAEEGVSAYPAEVTAQMVYNFANGGAAINVFSRRIDALLEIVDVGVAVPIEDERV
ECCCCCHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHH
IVKKVRHGTGNFAKTEAMTPEEAEQALHVGYERAARIIGQGARTFIAGEMGIGNTTAASA
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
LLATLTDEPLEHIVGKGTGIAAERLVHKQEVIRQALALHRPDPAKPIEWLAKIGGLEIAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHH
MAGAMLAAAERRIPILLDGFICTVAALVARQFAVNVTDYMIAGHRSQEPGHSIALRLLEK
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
DPLLDLGMRLGEGSGAAVAFPLLISAMAMVNEMATFASAGISTANAKGEKGR
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MMNSSIPPFCHEMVEEARAYLDQLTKPPGSLGRLEEVAVELAGMTGELHPRVTPPGVLVF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
AADHGIAEEGVSAYPAEVTAQMVYNFANGGAAINVFSRRIDALLEIVDVGVAVPIEDERV
ECCCCCHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEECCCCCCHH
IVKKVRHGTGNFAKTEAMTPEEAEQALHVGYERAARIIGQGARTFIAGEMGIGNTTAASA
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
LLATLTDEPLEHIVGKGTGIAAERLVHKQEVIRQALALHRPDPAKPIEWLAKIGGLEIAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHH
MAGAMLAAAERRIPILLDGFICTVAALVARQFAVNVTDYMIAGHRSQEPGHSIALRLLEK
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
DPLLDLGMRLGEGSGAAVAFPLLISAMAMVNEMATFASAGISTANAKGEKGR
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]