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The map label for this gene is ubiB [C]

Identifier: 138895306

GI number: 138895306

Start: 1741113

End: 1742789

Strand: Reverse

Name: ubiB [C]

Synonym: GTNG_1650

Alternate gene names: 138895306

Gene position: 1742789-1741113 (Counterclockwise)

Preceding gene: 138895307

Following gene: 138895304

Centisome position: 49.09

GC content: 52.65

Gene sequence:

>1677_bases
ATGATCGGAAAGCGGATGCGCCATATTGGTCGATATCATGAAATTGCCGTCGCCTTGCTTCGGCACGGATTCGGGATGAT
CGTCGATGAACTCGGTTTTTCGTCCTTTCTTTCCTTGCCGCCGCGCGGGCGAACCGAACAAGGGAAACGGGAAGGAAAAA
CGGTCGGAGAACGTCTGCGCCTTGTGCTCGAGGAACTCGGTCCGACATTTATTAAGCTTGGGCAAATCGCCAGCACGCGA
CCGGATTTGATCCCTCGATATATCATTTGCGAATTGGAAAAGTTGCAAGATCAAGTTCCACCGTTTCCATTTCCTGAGGT
CCGCCGGATTGTGGAAACAGAATTGGGAGGGCCGCTCGAGGAGCTTTTTCGATCATTTGACGAAATCCCACTAGCAGCCG
CTTCGCTCGGGCAAGTACATCGGGCCGTTCTTCCTTCCGGACAAGCTGTCGTGGTGAAAATACAGCGCCCGCATATTGCA
GCGCGGATTGAGACGGATTTGGATATTTTACAAGACTTAGCAGTGCTCGCGGAACGGCGCTTAGATTGGGCGGCGTCTTA
TCGGCTCACTGAAATCGTTGACGAATTGGCAAAGTCGCTGCGGCAGGAGCTCGATTACACCATCGAGGCGCGCCATGCGG
AAACGTTTGCTAATCAATTTGCCGATGACCCGTCTGTATACGTGCCCGGCGTTTTTTGGGAGTATACGACGAAACTAGTG
CTGACGATGGAATATGTGGAGGGGGTTAAGCTCGGGGAAATCGAGCGCCTGAAAGAGAGCGGTCATTCGTTAAAGACACT
GGCTGAGCGCTTGACTGTCTCGATGTTAAAGCAAATGTTCGAACATGGATTCTTCCATGGCGATCCTCATCCGGGCAATG
TATTCGTTCTCCCCGATGGGATGCTTGCCTTTATTGATTTCGGCTTAATGGGACGCCTCCGTCCGAATGTCAAGCATCAC
CTTTCCTCACTTATCATCGCTTTGATGCGGCAAAACACCGACGGGGTGTTGAACGCCATTTATGGCCTCGGGCTTGTTCC
GGCTGAGGTCGATGAGGGGAAGCTGCGCGACGATATTGACGAGTTGCGCGAGAAGTATTATCGTGTTCCGCTCAGCGAGG
TGAGCCTTGGCGAAGCGATCGGGGATCTTTTAACGGTGGCGTTTCGGCATGGCATTCGCATTCCGAGCGACTTGACGCTG
TTAGGGAAAGCGCTGTTGACGGTTGAAGGAGTGGTGGCGACGCTTGACCCTCAATTTCGCGTAATGGACGTTGCCGAACC
GTTCGGAAGAAAATTGCTGAAAGAGCGGCTTCGACTCGATCGCGTGGCAGAAACGGCGTGGAAGCGTGTGGCGGGTTATG
GCGAAATGCTGCTTCGGCTGCCGGACAGTATCAAAGAACTGACGAAGGTCATGCGGCGCGGCAAACTTCAGCTTGAGATG
ACAGCCTCAGACCTTGAGGCGCTTTTGCGCAAACTCGATCAAATTGGCAACCGATTGTCCATCAGCCTCATCCTTCTTTC
CTTGAGCATCGTCATGGCCGGCATGTTAATCGCTTCATCGCTAGGACGGCAGTCGATGCTCCTATGGAAAATTCCGATTA
TTGAAATTGGATTTGGTGTGGTCGCGCTCATGTTCGGGTGGTTGCTTTATTCGATCTTTCGATCAGGGAAGCTTTAG

Upstream 100 bases:

>100_bases
CGAGGAGCGAATCCGCCGCCTTGAAGAAAAGGAACAAAGCGGGCAGTAAACGAATACGGCCTGTCCGCTCGCTTTTTGCC
GTTGTAAGGGAGATGGTCGG

Downstream 100 bases:

>100_bases
TGCAAAAAAAGGGGGGTGTCCCCTTTTTCTTGTTGTGATTGAACGGTGTTTGTGGTGTCTTAGGCTTGTTGCGGCCATTT
ACGCATCGACTGTTGAATGC

Product: ABC transporter

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MIGKRMRHIGRYHEIAVALLRHGFGMIVDELGFSSFLSLPPRGRTEQGKREGKTVGERLRLVLEELGPTFIKLGQIASTR
PDLIPRYIICELEKLQDQVPPFPFPEVRRIVETELGGPLEELFRSFDEIPLAAASLGQVHRAVLPSGQAVVVKIQRPHIA
ARIETDLDILQDLAVLAERRLDWAASYRLTEIVDELAKSLRQELDYTIEARHAETFANQFADDPSVYVPGVFWEYTTKLV
LTMEYVEGVKLGEIERLKESGHSLKTLAERLTVSMLKQMFEHGFFHGDPHPGNVFVLPDGMLAFIDFGLMGRLRPNVKHH
LSSLIIALMRQNTDGVLNAIYGLGLVPAEVDEGKLRDDIDELREKYYRVPLSEVSLGEAIGDLLTVAFRHGIRIPSDLTL
LGKALLTVEGVVATLDPQFRVMDVAEPFGRKLLKERLRLDRVAETAWKRVAGYGEMLLRLPDSIKELTKVMRRGKLQLEM
TASDLEALLRKLDQIGNRLSISLILLSLSIVMAGMLIASSLGRQSMLLWKIPIIEIGFGVVALMFGWLLYSIFRSGKL

Sequences:

>Translated_558_residues
MIGKRMRHIGRYHEIAVALLRHGFGMIVDELGFSSFLSLPPRGRTEQGKREGKTVGERLRLVLEELGPTFIKLGQIASTR
PDLIPRYIICELEKLQDQVPPFPFPEVRRIVETELGGPLEELFRSFDEIPLAAASLGQVHRAVLPSGQAVVVKIQRPHIA
ARIETDLDILQDLAVLAERRLDWAASYRLTEIVDELAKSLRQELDYTIEARHAETFANQFADDPSVYVPGVFWEYTTKLV
LTMEYVEGVKLGEIERLKESGHSLKTLAERLTVSMLKQMFEHGFFHGDPHPGNVFVLPDGMLAFIDFGLMGRLRPNVKHH
LSSLIIALMRQNTDGVLNAIYGLGLVPAEVDEGKLRDDIDELREKYYRVPLSEVSLGEAIGDLLTVAFRHGIRIPSDLTL
LGKALLTVEGVVATLDPQFRVMDVAEPFGRKLLKERLRLDRVAETAWKRVAGYGEMLLRLPDSIKELTKVMRRGKLQLEM
TASDLEALLRKLDQIGNRLSISLILLSLSIVMAGMLIASSLGRQSMLLWKIPIIEIGFGVVALMFGWLLYSIFRSGKL
>Mature_558_residues
MIGKRMRHIGRYHEIAVALLRHGFGMIVDELGFSSFLSLPPRGRTEQGKREGKTVGERLRLVLEELGPTFIKLGQIASTR
PDLIPRYIICELEKLQDQVPPFPFPEVRRIVETELGGPLEELFRSFDEIPLAAASLGQVHRAVLPSGQAVVVKIQRPHIA
ARIETDLDILQDLAVLAERRLDWAASYRLTEIVDELAKSLRQELDYTIEARHAETFANQFADDPSVYVPGVFWEYTTKLV
LTMEYVEGVKLGEIERLKESGHSLKTLAERLTVSMLKQMFEHGFFHGDPHPGNVFVLPDGMLAFIDFGLMGRLRPNVKHH
LSSLIIALMRQNTDGVLNAIYGLGLVPAEVDEGKLRDDIDELREKYYRVPLSEVSLGEAIGDLLTVAFRHGIRIPSDLTL
LGKALLTVEGVVATLDPQFRVMDVAEPFGRKLLKERLRLDRVAETAWKRVAGYGEMLLRLPDSIKELTKVMRRGKLQLEM
TASDLEALLRKLDQIGNRLSISLILLSLSIVMAGMLIASSLGRQSMLLWKIPIIEIGFGVVALMFGWLLYSIFRSGKL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=272, Percent_Identity=33.4558823529412, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI41393593, Length=267, Percent_Identity=35.5805243445693, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI217035081, Length=227, Percent_Identity=33.4801762114537, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI27363457, Length=284, Percent_Identity=28.8732394366197, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI217416386, Length=248, Percent_Identity=29.8387096774194, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI34147522, Length=309, Percent_Identity=28.8025889967638, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI2367309, Length=508, Percent_Identity=31.8897637795276, Blast_Score=234, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17559152, Length=269, Percent_Identity=33.0855018587361, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32565180, Length=244, Percent_Identity=31.9672131147541, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=247, Percent_Identity=33.6032388663968, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323282, Length=249, Percent_Identity=30.9236947791165, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=451, Percent_Identity=22.6164079822616, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI22024280, Length=327, Percent_Identity=29.3577981651376, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24662575, Length=290, Percent_Identity=33.1034482758621, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI18859849, Length=293, Percent_Identity=30.0341296928328, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62752; Mature: 62752

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKRMRHIGRYHEIAVALLRHGFGMIVDELGFSSFLSLPPRGRTEQGKREGKTVGERLR
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LVLEELGPTFIKLGQIASTRPDLIPRYIICELEKLQDQVPPFPFPEVRRIVETELGGPLE
HHHHHHCHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHH
ELFRSFDEIPLAAASLGQVHRAVLPSGQAVVVKIQRPHIAARIETDLDILQDLAVLAERR
HHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHH
LDWAASYRLTEIVDELAKSLRQELDYTIEARHAETFANQFADDPSVYVPGVFWEYTTKLV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHH
LTMEYVEGVKLGEIERLKESGHSLKTLAERLTVSMLKQMFEHGFFHGDPHPGNVFVLPDG
HHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
MLAFIDFGLMGRLRPNVKHHLSSLIIALMRQNTDGVLNAIYGLGLVPAEVDEGKLRDDID
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
ELREKYYRVPLSEVSLGEAIGDLLTVAFRHGIRIPSDLTLLGKALLTVEGVVATLDPQFR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VMDVAEPFGRKLLKERLRLDRVAETAWKRVAGYGEMLLRLPDSIKELTKVMRRGKLQLEM
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
TASDLEALLRKLDQIGNRLSISLILLSLSIVMAGMLIASSLGRQSMLLWKIPIIEIGFGV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHH
VALMFGWLLYSIFRSGKL
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIGKRMRHIGRYHEIAVALLRHGFGMIVDELGFSSFLSLPPRGRTEQGKREGKTVGERLR
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LVLEELGPTFIKLGQIASTRPDLIPRYIICELEKLQDQVPPFPFPEVRRIVETELGGPLE
HHHHHHCHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHH
ELFRSFDEIPLAAASLGQVHRAVLPSGQAVVVKIQRPHIAARIETDLDILQDLAVLAERR
HHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHH
LDWAASYRLTEIVDELAKSLRQELDYTIEARHAETFANQFADDPSVYVPGVFWEYTTKLV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHH
LTMEYVEGVKLGEIERLKESGHSLKTLAERLTVSMLKQMFEHGFFHGDPHPGNVFVLPDG
HHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
MLAFIDFGLMGRLRPNVKHHLSSLIIALMRQNTDGVLNAIYGLGLVPAEVDEGKLRDDID
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHH
ELREKYYRVPLSEVSLGEAIGDLLTVAFRHGIRIPSDLTLLGKALLTVEGVVATLDPQFR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VMDVAEPFGRKLLKERLRLDRVAETAWKRVAGYGEMLLRLPDSIKELTKVMRRGKLQLEM
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEE
TASDLEALLRKLDQIGNRLSISLILLSLSIVMAGMLIASSLGRQSMLLWKIPIIEIGFGV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHH
VALMFGWLLYSIFRSGKL
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]