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The map label for this gene is xerC [H]

Identifier: 138895282

GI number: 138895282

Start: 1712508

End: 1713413

Strand: Reverse

Name: xerC [H]

Synonym: GTNG_1626

Alternate gene names: 138895282

Gene position: 1713413-1712508 (Counterclockwise)

Preceding gene: 138895284

Following gene: 138895276

Centisome position: 48.26

GC content: 35.87

Gene sequence:

>906_bases
ATGTTGTTTCGACAAGCCATTGATGAATTTGTGTTGTACTTGCAAATTGAAAAAAACTATTCACTTAACACCGTTGATGG
TTATGCTTATGATTTGAGATGTTTCGAGAACTTCTTAGTTCAACATGGTTATTCTGTACAACTTAATAGCATTACAAAAA
CGCATGTTCGTCGCTTCATCCAGCATCAAATTACAAAAGAAAATGTCAAGCCTCGAACGATCTATCGGAGAATTTCTTGC
TTGAAATCGTTCAGTAAATACTGTGTCAAAGAAAATCTAATCGACAACGATTTTATGATCGGAATTGATACTCCTAAAAC
GGATAGTAAATTACCGACTTATATGTCTTTGTCTGAACTACGAAAACTGTTTCATTTTTTGGAGCAAGACAATAGCCGAA
TGGCGATGCGAAACCATCTTCTATTTAAACTGTTAGCCACTACGGGTATGCGAAGATCTGAAATTGTTGAACTAACTTGG
GAACAAATTGATTTATCTAACAACACGATACGTATATATGGGAAAGGAAAAAAAGAGCGCTTACTCCCCCTTCATCCCAT
GGTTGTCCCTTTAATGAAAAGCTATATGGAAAGTTTAGAGGAATATCAGCTCCATCCTTCTCAACCAGTATTTTTAAATA
AAAACGGAAAAAAACTGAATCCGCGTGGTTTACATAAGATATTTAAAGACATCTTACAAAAAGCAGGTCTGCCACCTCAA
CGGTTCTCACTCCACCATTTGCGGCATACGTTTGCTACCTTGTTGATACAAGAAAATAAAGAAAATGTTGATTTGCGTAC
CGTACAAGAACTACTCGGTCATGAAAGTTTAGTCACGACGCAAGTATATACGCATGTTGACTTTGAGCAAAAGAAAAAAG
CGATTGAAACATTTAACATATTTTGA

Upstream 100 bases:

>100_bases
ATAATTTTTTGTGTCTACGAATTATCATTTTTTAAACGAATTATCATTATTTTTTTATCGATTATCATCGGTCGTTGATT
ATCAACTGGAGGTGTTTTTT

Downstream 100 bases:

>100_bases
AACCTGCTTAGTACGGAAATAACTACCCTAGCCGGGTAGTTATTTCCCCATGTGAATATGAGTTGGCGGATACAAAGGCA
CTGAATGCGTGAGATCGTAT

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLFRQAIDEFVLYLQIEKNYSLNTVDGYAYDLRCFENFLVQHGYSVQLNSITKTHVRRFIQHQITKENVKPRTIYRRISC
LKSFSKYCVKENLIDNDFMIGIDTPKTDSKLPTYMSLSELRKLFHFLEQDNSRMAMRNHLLFKLLATTGMRRSEIVELTW
EQIDLSNNTIRIYGKGKKERLLPLHPMVVPLMKSYMESLEEYQLHPSQPVFLNKNGKKLNPRGLHKIFKDILQKAGLPPQ
RFSLHHLRHTFATLLIQENKENVDLRTVQELLGHESLVTTQVYTHVDFEQKKKAIETFNIF

Sequences:

>Translated_301_residues
MLFRQAIDEFVLYLQIEKNYSLNTVDGYAYDLRCFENFLVQHGYSVQLNSITKTHVRRFIQHQITKENVKPRTIYRRISC
LKSFSKYCVKENLIDNDFMIGIDTPKTDSKLPTYMSLSELRKLFHFLEQDNSRMAMRNHLLFKLLATTGMRRSEIVELTW
EQIDLSNNTIRIYGKGKKERLLPLHPMVVPLMKSYMESLEEYQLHPSQPVFLNKNGKKLNPRGLHKIFKDILQKAGLPPQ
RFSLHHLRHTFATLLIQENKENVDLRTVQELLGHESLVTTQVYTHVDFEQKKKAIETFNIF
>Mature_301_residues
MLFRQAIDEFVLYLQIEKNYSLNTVDGYAYDLRCFENFLVQHGYSVQLNSITKTHVRRFIQHQITKENVKPRTIYRRISC
LKSFSKYCVKENLIDNDFMIGIDTPKTDSKLPTYMSLSELRKLFHFLEQDNSRMAMRNHLLFKLLATTGMRRSEIVELTW
EQIDLSNNTIRIYGKGKKERLLPLHPMVVPLMKSYMESLEEYQLHPSQPVFLNKNGKKLNPRGLHKIFKDILQKAGLPPQ
RFSLHHLRHTFATLLIQENKENVDLRTVQELLGHESLVTTQVYTHVDFEQKKKAIETFNIF

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=284, Percent_Identity=30.6338028169014, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789261, Length=289, Percent_Identity=29.0657439446367, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI2367104, Length=210, Percent_Identity=29.0476190476191, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35594; Mature: 35594

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRQAIDEFVLYLQIEKNYSLNTVDGYAYDLRCFENFLVQHGYSVQLNSITKTHVRRFI
CCHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHH
QHQITKENVKPRTIYRRISCLKSFSKYCVKENLIDNDFMIGIDTPKTDSKLPTYMSLSEL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHH
RKLFHFLEQDNSRMAMRNHLLFKLLATTGMRRSEIVELTWEQIDLSNNTIRIYGKGKKER
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEEECCCCCC
LLPLHPMVVPLMKSYMESLEEYQLHPSQPVFLNKNGKKLNPRGLHKIFKDILQKAGLPPQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHH
RFSLHHLRHTFATLLIQENKENVDLRTVQELLGHESLVTTQVYTHVDFEQKKKAIETFNI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCC
F
C
>Mature Secondary Structure
MLFRQAIDEFVLYLQIEKNYSLNTVDGYAYDLRCFENFLVQHGYSVQLNSITKTHVRRFI
CCHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHH
QHQITKENVKPRTIYRRISCLKSFSKYCVKENLIDNDFMIGIDTPKTDSKLPTYMSLSEL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHH
RKLFHFLEQDNSRMAMRNHLLFKLLATTGMRRSEIVELTWEQIDLSNNTIRIYGKGKKER
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEEECCCCCC
LLPLHPMVVPLMKSYMESLEEYQLHPSQPVFLNKNGKKLNPRGLHKIFKDILQKAGLPPQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHH
RFSLHHLRHTFATLLIQENKENVDLRTVQELLGHESLVTTQVYTHVDFEQKKKAIETFNI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]