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The map label for this gene is pksA [H]

Identifier: 138895162

GI number: 138895162

Start: 1585506

End: 1586096

Strand: Reverse

Name: pksA [H]

Synonym: GTNG_1500

Alternate gene names: 138895162

Gene position: 1586096-1585506 (Counterclockwise)

Preceding gene: 138895177

Following gene: 138895143

Centisome position: 44.67

GC content: 48.05

Gene sequence:

>591_bases
ATGCCTAAAATCGTGGATCATGAAAAGCAGAGGGAACGAATCGCAGAAGCGACATGGGCCGTGATCATGCGGGACGGTAT
CGAAAAAGCAACCGTACGAAATATCGCTAAAGAGGCAGGGATGTCTGCAGGGGCGCTACGCTATTACTTTTCTTCCCAAT
CGGAGTTGTTAGCCTTTTCGATGAAGCTTGTCTCCGAACGGGTGCGGAAACGGATTGAAGCCATCCCTCGCTCCACTCCG
CCTCTTGAAGGAATCAAACGTTGTCTCCTTGAAATTTTGCCGTTAACCGATGAAACGAAAAAAGAAATGGAGGTGTGGCT
TGTTTTTACACAAAGGGCGCTTTGGGATTCCGAACTTCAACCGCTGAGCGAGCAAATCTATAACGAGTTGCAAACGGCAA
TAAAGAGGTTGCTTGAACTGTTACGTAATCTCGGGTTGTTAAGACCCGACGTGTCGATTGAGTTGGAAACAGAGCGCCTA
TACGCTTTGGTTGACGGTTTGGCCATGCACGGCATCATGCAACCTGACAAGCTATCTCCTTCACAAATGGAAGAAATCAT
CGAGTATCACTTACGCTCCATCTGCCGCTAA

Upstream 100 bases:

>100_bases
TCAACCACCCAATCATATCAGCCGCCCCTTTTTAATACAATTGTATCAAAAAAATAGTAACACAATTGTATCAAAAAAAC
AACTGTGTTACACTAGATAC

Downstream 100 bases:

>100_bases
GGCAAATGGAGCGTCCCTACCTTTACTACCTAAAAAACCACCAACAATCAACGGCGACAGGCAAAAGACAGATGATTTTG
CCACTTCCTCGTTGATGGAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MPKIVDHEKQRERIAEATWAVIMRDGIEKATVRNIAKEAGMSAGALRYYFSSQSELLAFSMKLVSERVRKRIEAIPRSTP
PLEGIKRCLLEILPLTDETKKEMEVWLVFTQRALWDSELQPLSEQIYNELQTAIKRLLELLRNLGLLRPDVSIELETERL
YALVDGLAMHGIMQPDKLSPSQMEEIIEYHLRSICR

Sequences:

>Translated_196_residues
MPKIVDHEKQRERIAEATWAVIMRDGIEKATVRNIAKEAGMSAGALRYYFSSQSELLAFSMKLVSERVRKRIEAIPRSTP
PLEGIKRCLLEILPLTDETKKEMEVWLVFTQRALWDSELQPLSEQIYNELQTAIKRLLELLRNLGLLRPDVSIELETERL
YALVDGLAMHGIMQPDKLSPSQMEEIIEYHLRSICR
>Mature_195_residues
PKIVDHEKQRERIAEATWAVIMRDGIEKATVRNIAKEAGMSAGALRYYFSSQSELLAFSMKLVSERVRKRIEAIPRSTPP
LEGIKRCLLEILPLTDETKKEMEVWLVFTQRALWDSELQPLSEQIYNELQTAIKRLLELLRNLGLLRPDVSIELETERLY
ALVDGLAMHGIMQPDKLSPSQMEEIIEYHLRSICR

Specific function: Transcriptional regulation of the polyketide synthase operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22677; Mature: 22546

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIVDHEKQRERIAEATWAVIMRDGIEKATVRNIAKEAGMSAGALRYYFSSQSELLAFS
CCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
MKLVSERVRKRIEAIPRSTPPLEGIKRCLLEILPLTDETKKEMEVWLVFTQRALWDSELQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
PLSEQIYNELQTAIKRLLELLRNLGLLRPDVSIELETERLYALVDGLAMHGIMQPDKLSP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCH
SQMEEIIEYHLRSICR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKIVDHEKQRERIAEATWAVIMRDGIEKATVRNIAKEAGMSAGALRYYFSSQSELLAFS
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
MKLVSERVRKRIEAIPRSTPPLEGIKRCLLEILPLTDETKKEMEVWLVFTQRALWDSELQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
PLSEQIYNELQTAIKRLLELLRNLGLLRPDVSIELETERLYALVDGLAMHGIMQPDKLSP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCH
SQMEEIIEYHLRSICR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]