Click here to switch to the map view.

The map label for this gene is gerXA [H]

Identifier: 138895127

GI number: 138895127

Start: 1546911

End: 1548446

Strand: Reverse

Name: gerXA [H]

Synonym: GTNG_1465

Alternate gene names: 138895127

Gene position: 1548446-1546911 (Counterclockwise)

Preceding gene: 138895128

Following gene: 138895126

Centisome position: 43.61

GC content: 49.02

Gene sequence:

>1536_bases
ATGAAACCGATTATGCGCGCCGCCCAAGGCAAGCGGCTGAACGACGATTACACCGGATTAGAGACTGTGATCATCTCCGA
AGAGGCATTACAGATGATGTACGCGAAATGCAGCGACGTCATCATGACAGAGACGGTCGTTCCATCGCTGCTCTCTGATG
GGTCATCAAAAACTGTACACTTGTTATTTATTTATTGTGAGGAATTGTGCGATGTACAAATGTTGCAAAAGACCATCTAC
CCAATGTTCCGCAAGATTTGTGAACAGCATTCGTGCTTCTCGCACGCTGATATCGAAACTTGCAAACCACCCGCGCTCGA
ATACATGGGGCACGAAGTGCGAATCGATGATCTCAACTTAAGACTGTTTAGCGGCGATTTGCTCATTTATTTCCGCGAAG
CCGACGCCTTATACGCAATGCCGCTTGCGAGTCCGCCCAACCGTGACCCAGAGGAGCCAAACACGGAAGTGTCGATTCGC
GGACCAAAAGACGGATTTATTGAAGAGATCAACAAGAACGTGGCGCTCATCCGCAAACGGCTGCGCTCAAATTGTCTCGC
CTATGAGTCGTTCATTATCGGCACACGCAGCCAGACAAAAGTTGCGCTGCTCTACGTCGAAGATATTGCCAACACAGCCA
TCATCGATGAGGTGAGAAGACGGCTGCTCAGCTTATACATTGACTCGGTAACAAGCACCTCTCAAATTGAAGAGTGGCTG
TCCGACACCAAGATTGCTTTGTTTCCAATGTTCGGTTATACCGGGCGCCCTGATTTTGCCGTCAATTCGCTTCTCAATGG
CCGTTTTATCATCTTAGTGGACGGGTCACCGACCGCCTTGATTGGACCGGGCAATTTAACGTTTTTGCTAAACACATCGG
AAGATAATAACACATTTTTCCTATTTGTTGTATTTCAGCGTCTGCTTCGGCTTGTTGGCACCTCGGTCGCCATTTATTTG
CCAGGCGCCTGGATCGCACTCACTTCGTTCCATCCAGATCAGCTGCCATTCACCTTACTCGCAACGCTCATTTTGTCGCG
CCAAGGAGTGCCACTTCCGGTGCCGCTTGAAATGTTTATCATGATGATTTTGTTTGAAGTGTTTAAAGAAGCTGGGATGC
GACTGCCAATCGCCATCGGGCAGACGCTGTCGGTTGTTGGCGGTTTGATTATCGGACAAGCGGCGATCAACGCCGGGCTC
GCGGCCCCGGCCACACTCGTTGTTGCCGCTATTTCTGTCATCTCGACATTTACGCTTGTCAATCAAAACATCGCCGGCAG
CGTCACTTTGCTGCGCTTTATTGTTCTCATTTTCGCTTCCTCCCTTGGTTTGTTTGGGTTTATTTTGTCGCTGTTTTTCT
TTTTGACCTATATCGTCAACTTGCACATTTTTGGCATTCCGTACTTGACACCGCTAGCACCGCCTTCAAAAGATATCGGG
AAAGTATTTATTCCAAGCACGTGGAAACAGTTCCGCACGCGCGACCGCATTGTGCGTCCAAAAGATCTCATTGCAAAAGA
GAGGGAACGGCAATGA

Upstream 100 bases:

>100_bases
GGGTACTACCATCGTCGCTGCTGTTTAGTCTTGCGCTGTCTGTTTTGTTAGGCGGTTTGGCTTTATTGACGCACCGTAAA
AAGAAAAGAGGGATGGCATC

Downstream 100 bases:

>100_bases
GGAATCGGGTCATTCCCATCATCGTCTCTGTCCTGTTGCTTGGCGGTTGCTGGGATACACGCAATATCGATCAAACTGTC
TACGTCCATTCCATCGGGGT

Product: spore germination protein XA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MKPIMRAAQGKRLNDDYTGLETVIISEEALQMMYAKCSDVIMTETVVPSLLSDGSSKTVHLLFIYCEELCDVQMLQKTIY
PMFRKICEQHSCFSHADIETCKPPALEYMGHEVRIDDLNLRLFSGDLLIYFREADALYAMPLASPPNRDPEEPNTEVSIR
GPKDGFIEEINKNVALIRKRLRSNCLAYESFIIGTRSQTKVALLYVEDIANTAIIDEVRRRLLSLYIDSVTSTSQIEEWL
SDTKIALFPMFGYTGRPDFAVNSLLNGRFIILVDGSPTALIGPGNLTFLLNTSEDNNTFFLFVVFQRLLRLVGTSVAIYL
PGAWIALTSFHPDQLPFTLLATLILSRQGVPLPVPLEMFIMMILFEVFKEAGMRLPIAIGQTLSVVGGLIIGQAAINAGL
AAPATLVVAAISVISTFTLVNQNIAGSVTLLRFIVLIFASSLGLFGFILSLFFFLTYIVNLHIFGIPYLTPLAPPSKDIG
KVFIPSTWKQFRTRDRIVRPKDLIAKERERQ

Sequences:

>Translated_511_residues
MKPIMRAAQGKRLNDDYTGLETVIISEEALQMMYAKCSDVIMTETVVPSLLSDGSSKTVHLLFIYCEELCDVQMLQKTIY
PMFRKICEQHSCFSHADIETCKPPALEYMGHEVRIDDLNLRLFSGDLLIYFREADALYAMPLASPPNRDPEEPNTEVSIR
GPKDGFIEEINKNVALIRKRLRSNCLAYESFIIGTRSQTKVALLYVEDIANTAIIDEVRRRLLSLYIDSVTSTSQIEEWL
SDTKIALFPMFGYTGRPDFAVNSLLNGRFIILVDGSPTALIGPGNLTFLLNTSEDNNTFFLFVVFQRLLRLVGTSVAIYL
PGAWIALTSFHPDQLPFTLLATLILSRQGVPLPVPLEMFIMMILFEVFKEAGMRLPIAIGQTLSVVGGLIIGQAAINAGL
AAPATLVVAAISVISTFTLVNQNIAGSVTLLRFIVLIFASSLGLFGFILSLFFFLTYIVNLHIFGIPYLTPLAPPSKDIG
KVFIPSTWKQFRTRDRIVRPKDLIAKERERQ
>Mature_511_residues
MKPIMRAAQGKRLNDDYTGLETVIISEEALQMMYAKCSDVIMTETVVPSLLSDGSSKTVHLLFIYCEELCDVQMLQKTIY
PMFRKICEQHSCFSHADIETCKPPALEYMGHEVRIDDLNLRLFSGDLLIYFREADALYAMPLASPPNRDPEEPNTEVSIR
GPKDGFIEEINKNVALIRKRLRSNCLAYESFIIGTRSQTKVALLYVEDIANTAIIDEVRRRLLSLYIDSVTSTSQIEEWL
SDTKIALFPMFGYTGRPDFAVNSLLNGRFIILVDGSPTALIGPGNLTFLLNTSEDNNTFFLFVVFQRLLRLVGTSVAIYL
PGAWIALTSFHPDQLPFTLLATLILSRQGVPLPVPLEMFIMMILFEVFKEAGMRLPIAIGQTLSVVGGLIIGQAAINAGL
AAPATLVVAAISVISTFTLVNQNIAGSVTLLRFIVLIFASSLGLFGFILSLFFFLTYIVNLHIFGIPYLTPLAPPSKDIG
KVFIPSTWKQFRTRDRIVRPKDLIAKERERQ

Specific function: May allow B.anthracis to germinate within phagocytic cells and therefore involved in virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gerABKA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004995 [H]

Pfam domain/function: PF03323 GerA [H]

EC number: NA

Molecular weight: Translated: 57083; Mature: 57083

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIMRAAQGKRLNDDYTGLETVIISEEALQMMYAKCSDVIMTETVVPSLLSDGSSKTVH
CCCHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LLFIYCEELCDVQMLQKTIYPMFRKICEQHSCFSHADIETCKPPALEYMGHEVRIDDLNL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEEEEEEEE
RLFSGDLLIYFREADALYAMPLASPPNRDPEEPNTEVSIRGPKDGFIEEINKNVALIRKR
EEEECCEEEEEEECCCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCHHHHHHH
LRSNCLAYESFIIGTRSQTKVALLYVEDIANTAIIDEVRRRLLSLYIDSVTSTSQIEEWL
HHHHHHHHHHHEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SDTKIALFPMFGYTGRPDFAVNSLLNGRFIILVDGSPTALIGPGNLTFLLNTSEDNNTFF
CCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCEEE
LFVVFQRLLRLVGTSVAIYLPGAWIALTSFHPDQLPFTLLATLILSRQGVPLPVPLEMFI
EHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
MMILFEVFKEAGMRLPIAIGQTLSVVGGLIIGQAAINAGLAAPATLVVAAISVISTFTLV
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
NQNIAGSVTLLRFIVLIFASSLGLFGFILSLFFFLTYIVNLHIFGIPYLTPLAPPSKDIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KVFIPSTWKQFRTRDRIVRPKDLIAKERERQ
EEECCCHHHHHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKPIMRAAQGKRLNDDYTGLETVIISEEALQMMYAKCSDVIMTETVVPSLLSDGSSKTVH
CCCHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LLFIYCEELCDVQMLQKTIYPMFRKICEQHSCFSHADIETCKPPALEYMGHEVRIDDLNL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEEEEEEEE
RLFSGDLLIYFREADALYAMPLASPPNRDPEEPNTEVSIRGPKDGFIEEINKNVALIRKR
EEEECCEEEEEEECCCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCHHHHHHH
LRSNCLAYESFIIGTRSQTKVALLYVEDIANTAIIDEVRRRLLSLYIDSVTSTSQIEEWL
HHHHHHHHHHHEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SDTKIALFPMFGYTGRPDFAVNSLLNGRFIILVDGSPTALIGPGNLTFLLNTSEDNNTFF
CCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCEEE
LFVVFQRLLRLVGTSVAIYLPGAWIALTSFHPDQLPFTLLATLILSRQGVPLPVPLEMFI
EHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
MMILFEVFKEAGMRLPIAIGQTLSVVGGLIIGQAAINAGLAAPATLVVAAISVISTFTLV
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
NQNIAGSVTLLRFIVLIFASSLGLFGFILSLFFFLTYIVNLHIFGIPYLTPLAPPSKDIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KVFIPSTWKQFRTRDRIVRPKDLIAKERERQ
EEECCCHHHHHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10411756; 10515943; 12004073; 12067380 [H]