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The map label for this gene is cbaA [H]

Identifier: 138895056

GI number: 138895056

Start: 1485511

End: 1487160

Strand: Reverse

Name: cbaA [H]

Synonym: GTNG_1394

Alternate gene names: 138895056

Gene position: 1487160-1485511 (Counterclockwise)

Preceding gene: 138895057

Following gene: 138895039

Centisome position: 41.89

GC content: 52.36

Gene sequence:

>1650_bases
ATGGTACAACCGTTGGAAAAAGTCGATCGCCGCGACGCCAAACTGGCGTTGGCGCATTTATTTGTCGCTTTTATCGCTCT
CGGATTAGGCGGCTTTGCCGGCTTATTGCAAACGCTCGTCCGTTCCGGCAAGTTTGAATTGCCGGGTGGCATCAGCTACT
ATACGATTTTAACAACGCACGGCGTCTTGCTCGGGCTTGTACTGACGACCTTTTTCATTATCGGCTTTCAGTTTGCTGCT
GTCAGCCGCACGGCTGGGACATTCACGGACAGCACGCGCCGGGTCGGATGGATTGGTTTTTGGCTGATGACGATTGGAAC
AGCCATGAGCGCCTTTTTCATCCTCACGGGGCAAGCGGCTGTATTGTATACATTTTATGCCCCGCTGCAAGCGCATGCCG
GCTTTTACATCGGTTTAGCGCTTGTTGTCGTCGGCAGCTGGGTGAGCGGTTTTGCAATGTTTGCCCATTATGCGCGCTGG
CGGAAAGCGCATCGCGGCCAGGCGAGCCCGTTGTTGACATTCATGTCAGTAACGAATATGGCGCTATGGCTCATCTGTAC
GCTCGGTGTTGCCGCAACCGTCGTCTTTCAGCTTATCCCATGGTCGCTCGGGCTCTCTGAACGGGTGAACGTGCTGTTAA
GCCGGACGCTGTTTTGGTATTTCGGGCATCCGCTCGTTTACTTCTGGCTGTTGCCGGCGTATATGGTTTGGTACGCCGTC
ATTCCGAAAGTGATCGGGGGCAAAATGTTCTCCGATTCGCTCGCACGGTTAGCGTTTATCTTGTTCTTGCTGTTTTCGAT
TCCGGTCGGTTTCCACCATCAATTGCTTGAGCCGGGGATTTCACCGTTTTGGAAATACGTGCAAGTCGTCTTGACGTTTA
TGGTCATCATTCCATCATTGATGACGGCGTTCTCCATGTTTGCGACATTTGAATCATACGGCCGCTCGCAAGGAGCAAAA
GGCTTGTTTGGCTGGCTGCGGAAACTGCCGTGGGGAGATGCGCGCTTTTTCGCACCGTTTGTCGGAATGCTGTTTTTCAT
TCCGGCCGGTACAGGCGGGATTATTAACGCCTCGCATCAGCTCAACCAAGTCGTCCATAATACGATTTGGGTGACTGGGC
ACTTCCATCTGACGGTGGCGACAACCGTTGTCTTAACATTTTTCGGTGCATCGTACTGGCTCATCCCGCATTTGACCGGT
CGGGTGCTGACGAAGGCGATGAACCGCCTTGCCATCATTCAAACGATCGTTTGGGCCGTCGGGATGACATTTATGTCCGG
CTCGATGCATTTTGCCGGTTTGCTTGGGGCACCGAGACGTTCAGCGTTCTCAACGTACGGCAATTCGCCGCAAGCACTTG
AATGGATTCCGTACCAAATCGCACAAGCTGTCGGCGGAACGATCTTGTTTATCGGCATTATTCTCATGCTCGTCATCGTC
ATCAATTTGGCGTTTTTCGCTCCGAAAGGCGAAACAGAATTTCCAGTCGCCGAAGCGGCCACCCCGCAGGAACGGGTCGT
GTTGGTGTTTGAAAACTGGAAACTTTGGATCGGCATTGTCGTTGCGCTTATTTTGATCGCATATACCGTTCCGCTCATCG
ACATTATTCAAAACGCCCCGCCAGGGTCGAAAGGATATAAATTATGGTAA

Upstream 100 bases:

>100_bases
GCTACGTTTGATGAACCGGGCGAATATACGATCCTTTGTAATGAATATTGCGGCGCCGGCCATCATATGATGACGGCACG
CATTAAGGTGGTGGAGTAAC

Downstream 100 bases:

>100_bases
AAGCTATCCCCCTCTTCACACCGAAGAGGGGGATATTGTTTGAGCTGCTTCCACGTCGTCTCGCTTGAATCCGAAGACTT
CCTCAGCAACGATGTTACAG

Product: subunit I of b(o/a)3-type cytochrome c oxidase

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MVQPLEKVDRRDAKLALAHLFVAFIALGLGGFAGLLQTLVRSGKFELPGGISYYTILTTHGVLLGLVLTTFFIIGFQFAA
VSRTAGTFTDSTRRVGWIGFWLMTIGTAMSAFFILTGQAAVLYTFYAPLQAHAGFYIGLALVVVGSWVSGFAMFAHYARW
RKAHRGQASPLLTFMSVTNMALWLICTLGVAATVVFQLIPWSLGLSERVNVLLSRTLFWYFGHPLVYFWLLPAYMVWYAV
IPKVIGGKMFSDSLARLAFILFLLFSIPVGFHHQLLEPGISPFWKYVQVVLTFMVIIPSLMTAFSMFATFESYGRSQGAK
GLFGWLRKLPWGDARFFAPFVGMLFFIPAGTGGIINASHQLNQVVHNTIWVTGHFHLTVATTVVLTFFGASYWLIPHLTG
RVLTKAMNRLAIIQTIVWAVGMTFMSGSMHFAGLLGAPRRSAFSTYGNSPQALEWIPYQIAQAVGGTILFIGIILMLVIV
INLAFFAPKGETEFPVAEAATPQERVVLVFENWKLWIGIVVALILIAYTVPLIDIIQNAPPGSKGYKLW

Sequences:

>Translated_549_residues
MVQPLEKVDRRDAKLALAHLFVAFIALGLGGFAGLLQTLVRSGKFELPGGISYYTILTTHGVLLGLVLTTFFIIGFQFAA
VSRTAGTFTDSTRRVGWIGFWLMTIGTAMSAFFILTGQAAVLYTFYAPLQAHAGFYIGLALVVVGSWVSGFAMFAHYARW
RKAHRGQASPLLTFMSVTNMALWLICTLGVAATVVFQLIPWSLGLSERVNVLLSRTLFWYFGHPLVYFWLLPAYMVWYAV
IPKVIGGKMFSDSLARLAFILFLLFSIPVGFHHQLLEPGISPFWKYVQVVLTFMVIIPSLMTAFSMFATFESYGRSQGAK
GLFGWLRKLPWGDARFFAPFVGMLFFIPAGTGGIINASHQLNQVVHNTIWVTGHFHLTVATTVVLTFFGASYWLIPHLTG
RVLTKAMNRLAIIQTIVWAVGMTFMSGSMHFAGLLGAPRRSAFSTYGNSPQALEWIPYQIAQAVGGTILFIGIILMLVIV
INLAFFAPKGETEFPVAEAATPQERVVLVFENWKLWIGIVVALILIAYTVPLIDIIQNAPPGSKGYKLW
>Mature_549_residues
MVQPLEKVDRRDAKLALAHLFVAFIALGLGGFAGLLQTLVRSGKFELPGGISYYTILTTHGVLLGLVLTTFFIIGFQFAA
VSRTAGTFTDSTRRVGWIGFWLMTIGTAMSAFFILTGQAAVLYTFYAPLQAHAGFYIGLALVVVGSWVSGFAMFAHYARW
RKAHRGQASPLLTFMSVTNMALWLICTLGVAATVVFQLIPWSLGLSERVNVLLSRTLFWYFGHPLVYFWLLPAYMVWYAV
IPKVIGGKMFSDSLARLAFILFLLFSIPVGFHHQLLEPGISPFWKYVQVVLTFMVIIPSLMTAFSMFATFESYGRSQGAK
GLFGWLRKLPWGDARFFAPFVGMLFFIPAGTGGIINASHQLNQVVHNTIWVTGHFHLTVATTVVLTFFGASYWLIPHLTG
RVLTKAMNRLAIIQTIVWAVGMTFMSGSMHFAGLLGAPRRSAFSTYGNSPQALEWIPYQIAQAVGGTILFIGIILMLVIV
INLAFFAPKGETEFPVAEAATPQERVVLVFENWKLWIGIVVALILIAYTVPLIDIIQNAPPGSKGYKLW

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=278, Percent_Identity=24.4604316546763, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6226519, Length=238, Percent_Identity=25.6302521008403, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60745; Mature: 60745

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCC
>Mature Secondary Structure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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]