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The map label for this gene is kinD [H]

Identifier: 138895034

GI number: 138895034

Start: 1456534

End: 1457637

Strand: Reverse

Name: kinD [H]

Synonym: GTNG_1372

Alternate gene names: 138895034

Gene position: 1457637-1456534 (Counterclockwise)

Preceding gene: 138895038

Following gene: 138895033

Centisome position: 41.06

GC content: 46.01

Gene sequence:

>1104_bases
TTGGTATCTGCCGCACAACAGCTCGTCACCCATTTAGAAGCCCATCTGCCTTGCTTTCTTGCCCATTGGCGGCAACAGAT
GAAAATTGCCGCTGATGATAAATACATTGACCGTGTTGAGCAAAATAGCTTGGCAATGTTTACGCTAGTCAAAGAAGCGT
TGTCGCAGTCGCTGTCCGGTGAGACCGTTGAACGACTAGCCAACAAAGTCGCCAAGGAACGGGCGGAAATGAACGCCGGG
ATCGGAACCCTTGTCTACAACGTTAACTTGGGGCGGCGGTTGATCATTAAGCACGCGTTAACCGCGCCATTGCCGATCAC
CGAGCTAGCTCCGCTCATCGACCATATGAACGAGCTGTTTGACCAATTTTTATTTCATGCCGTCAAGGAATATAACGAAC
TGAAAGAAGCAGAGCTGCGCGAGAAAAATATGTTGATCGCCAGGTCGCACCAAGATCGGCTGACCTTGCTCGGGCAAATG
TCGTCTAGTTTTGTGCACGAATTTCGTAATCCACTGACAGCCATTATCGGTTTTATCCAATTGTTAAAATTTGAGCATCC
TCATTTGCCATATTTAGACATTATCGATCATGAACTGCAGCAGCTGAAATTTCGCATTTCACAATTTTTGCATGCCTCGC
GCAAAGAAATTGTTGAGAGCGAAAAAGAAACATTTTCGCTGCGCCAATTGTTAGAGGAAATCATGGATTTTTTATACGCG
ACGATCGTCGACAGCGATGTCGACATTTCGTTGGCGATCGATGAATCAATACATATTTTTGCCTATAAAGACCAACTTCG
CCAAGTATTAGTAAACATTTTGCTTAACTCGATCGAAGCGGTAAAAGAAAAGGAAAAGCCGCGCCGCATCAAGATTGCTG
CCCGCTCCCAAGAAGGAAGGGTCATCATTGAAATCGCCAACAACGGTCCGGCGATTCCTGCTGATATTGTCGAAACCATT
TTTGAGCCGTTTTTTACGACAAAAAAATTAGGGACGGGCATCGGCCTTTACATTTGTAAAAAAGTGATCGAAGACCACGG
CGGGGAAATCAGCTGTTCGTCTGATGCCAACATGACGACCTTCTCCATCCGGTTGCCTGTATAA

Upstream 100 bases:

>100_bases
AAAACTAGTTTTATCGGATTATATTATGATTTTCCCTCTGTTCTAGTTCGATATTCCCTCTTATAATGATAATAAAAGAT
GGAAAGAGAGGTGGATTTTT

Downstream 100 bases:

>100_bases
TGAGCGGCGGAAACGGGCATGCTGGATGAAAAAAGGTGATGCTGATGAAACTGTCATGGAAAAATTGGATAAAGCAAACA
ACTTCTGCCCTCCATGAATG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Sensor histidine kinase D [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MVSAAQQLVTHLEAHLPCFLAHWRQQMKIAADDKYIDRVEQNSLAMFTLVKEALSQSLSGETVERLANKVAKERAEMNAG
IGTLVYNVNLGRRLIIKHALTAPLPITELAPLIDHMNELFDQFLFHAVKEYNELKEAELREKNMLIARSHQDRLTLLGQM
SSSFVHEFRNPLTAIIGFIQLLKFEHPHLPYLDIIDHELQQLKFRISQFLHASRKEIVESEKETFSLRQLLEEIMDFLYA
TIVDSDVDISLAIDESIHIFAYKDQLRQVLVNILLNSIEAVKEKEKPRRIKIAARSQEGRVIIEIANNGPAIPADIVETI
FEPFFTTKKLGTGIGLYICKKVIEDHGGEISCSSDANMTTFSIRLPV

Sequences:

>Translated_367_residues
MVSAAQQLVTHLEAHLPCFLAHWRQQMKIAADDKYIDRVEQNSLAMFTLVKEALSQSLSGETVERLANKVAKERAEMNAG
IGTLVYNVNLGRRLIIKHALTAPLPITELAPLIDHMNELFDQFLFHAVKEYNELKEAELREKNMLIARSHQDRLTLLGQM
SSSFVHEFRNPLTAIIGFIQLLKFEHPHLPYLDIIDHELQQLKFRISQFLHASRKEIVESEKETFSLRQLLEEIMDFLYA
TIVDSDVDISLAIDESIHIFAYKDQLRQVLVNILLNSIEAVKEKEKPRRIKIAARSQEGRVIIEIANNGPAIPADIVETI
FEPFFTTKKLGTGIGLYICKKVIEDHGGEISCSSDANMTTFSIRLPV
>Mature_367_residues
MVSAAQQLVTHLEAHLPCFLAHWRQQMKIAADDKYIDRVEQNSLAMFTLVKEALSQSLSGETVERLANKVAKERAEMNAG
IGTLVYNVNLGRRLIIKHALTAPLPITELAPLIDHMNELFDQFLFHAVKEYNELKEAELREKNMLIARSHQDRLTLLGQM
SSSFVHEFRNPLTAIIGFIQLLKFEHPHLPYLDIIDHELQQLKFRISQFLHASRKEIVESEKETFSLRQLLEEIMDFLYA
TIVDSDVDISLAIDESIHIFAYKDQLRQVLVNILLNSIEAVKEKEKPRRIKIAARSQEGRVIIEIANNGPAIPADIVETI
FEPFFTTKKLGTGIGLYICKKVIEDHGGEISCSSDANMTTFSIRLPV

Specific function: Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=34.375, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=27.6679841897233, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790300, Length=224, Percent_Identity=27.2321428571429, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=295, Percent_Identity=26.7796610169492, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=27.4193548387097, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=268, Percent_Identity=23.5074626865672, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=212, Percent_Identity=27.8301886792453, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=24.4444444444444, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41795; Mature: 41795

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSAAQQLVTHLEAHLPCFLAHWRQQMKIAADDKYIDRVEQNSLAMFTLVKEALSQSLSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCC
ETVERLANKVAKERAEMNAGIGTLVYNVNLGRRLIIKHALTAPLPITELAPLIDHMNELF
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DQFLFHAVKEYNELKEAELREKNMLIARSHQDRLTLLGQMSSSFVHEFRNPLTAIIGFIQ
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKFEHPHLPYLDIIDHELQQLKFRISQFLHASRKEIVESEKETFSLRQLLEEIMDFLYA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVDSDVDISLAIDESIHIFAYKDQLRQVLVNILLNSIEAVKEKEKPRRIKIAARSQEGR
HHHCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
VIIEIANNGPAIPADIVETIFEPFFTTKKLGTGIGLYICKKVIEDHGGEISCSSDANMTT
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCEEE
FSIRLPV
EEEEECC
>Mature Secondary Structure
MVSAAQQLVTHLEAHLPCFLAHWRQQMKIAADDKYIDRVEQNSLAMFTLVKEALSQSLSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCC
ETVERLANKVAKERAEMNAGIGTLVYNVNLGRRLIIKHALTAPLPITELAPLIDHMNELF
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
DQFLFHAVKEYNELKEAELREKNMLIARSHQDRLTLLGQMSSSFVHEFRNPLTAIIGFIQ
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKFEHPHLPYLDIIDHELQQLKFRISQFLHASRKEIVESEKETFSLRQLLEEIMDFLYA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVDSDVDISLAIDESIHIFAYKDQLRQVLVNILLNSIEAVKEKEKPRRIKIAARSQEGR
HHHCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE
VIIEIANNGPAIPADIVETIFEPFFTTKKLGTGIGLYICKKVIEDHGGEISCSSDANMTT
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCEEE
FSIRLPV
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]