Click here to switch to the map view.

The map label for this gene is 138895030

Identifier: 138895030

GI number: 138895030

Start: 1453589

End: 1455130

Strand: Reverse

Name: 138895030

Synonym: GTNG_1368

Alternate gene names: NA

Gene position: 1455130-1453589 (Counterclockwise)

Preceding gene: 138895031

Following gene: 138895025

Centisome position: 40.99

GC content: 54.15

Gene sequence:

>1542_bases
ATGTCCAAGAGCAGCTGCGTCTGGATATACAAGCAGCACAACAAATGGTGCAATCGGCCGGTCACTAAATGGATTCATGG
GATTCCCCTGTCAAAGGGAGAATCCCATTTTTCATCATTTGCCCGTCATTCGCCCATCCTAACAAAAAAGGAGGTGAACA
TGGTGAAACGCCGATCGACAATATGGATAGCCATCAGTGCAGTCGTCGTCTTGATTGTCGTCGCTGCCGTTAGTTTCAGC
CGGCCGGCGACCGAAAAAAACGCTCCTGTCCCTCCGCGGCTTAAGCCGTTTGACACCAAAGACGCGCACACGCATCCGAC
TGTCGTCACCCTAGACAGCCTTAGCGCAGGGGAACAGCTGAAACAACGATTAAACGAGCATCCACGCATCCAAGAAATCC
GCCATAACCGCCGCGGCGACCGAAGCCACTACTTTTATAATGAAATTATCGTCCGTTTCCGGACAACACCTGCGAACCAT
GACATTCGGCAAATGGAGGCGGCCATTGCCGGACGGCTGGTCAAACGGTTGAATCAGGCGTTTGTGTTCCGTTCGCACAA
ACGAACGTACGAGGAAATGCGCCGCTATTTCCGTACGCTTCCGACAGTTGATTATTGCGAGCCGAACTACATTTACATGC
AAAACGACCTTCCGCGGCAAACGGATGTGCCGAACGACTCGTTTTACGCCCGTTACCAATGGAATTTGCCCGCCATTGAT
ACAGAAGCCGGCTGGACGTTGTCACGCGGCAAACAAACCGTACCTGTCGCCATCATCGACAGCGGGGTCGACCTAACTCA
CCCTGATTTAGCCCATCGACTCAGCCACGGATACAACGTGTTGGCTGATAACCGCTCTCCGGATGACGAAAACGGCCATG
GCACCCATGTGGCCGGCATTATCGCCTCACAACCAAACAATGGGGAAGGGATCGCCGGCATCACATGGTTCAACCCAATC
ATGGCAGTCAAGGTGTTAAACGCTGACGGCTACGGGACGAGCATCGATGTAGCCAAAGGCATCTATTGGGCGGTTGACCG
CGGGGCGAAAGTCATTAATTTAAGCCTCGGCAATTACCAGCCATCTTCGGTGCTCGAGGAAGCGATCCGATACGCTGATG
CCCATGACGTCGTGCTTGTGGCGGCTTCCGGCAATGACAGCACGTCCCAGCCGAGCTTTCCGGCCGCTTACCCGGAAGTG
ATCAGTGTTGGGGCTGTAGACCCTGATCTTTCGTACGCATTGTACTCTAACTATGGCGATTATGTAGACGTCGTCGCGCC
TGGAACAAACATTGCCAGCACGTTTACCGGACATCGGTACGCCGCCCTTTCCGGCACGTCAATGGCTGCGCCGCACGTCA
CCGCACTCGCTGCCTTAATTCGCTCGGTCAACCCGCGCCTCACCAATGACGAAGTGCGCAATATTATTATTCAAAGTGCT
GACGATTTGGGCGACCGCGGAAAAGACCCGCATTACGGCTATGGGCTCATTAACGTCTACCGCGCGCTCGAGTTGGCTAA
ATCCGCAGCCGCTTCGTCATAA

Upstream 100 bases:

>100_bases
GAAGTGCGCAACATACTGAAACAACATTTAAATGACGCGATTGCATTTCATGAACAAATTAGCCAATATATGGTCAACAA
AGGATACTATCATCCGACCA

Downstream 100 bases:

>100_bases
GCCATTCTCTCGCTCCATTGACATGGTGTACGTTTTTCCGCCTCCAAACGTCAAAGTGGCTCGACATAGTCTTCGCCCAT
AAGAAGAGCTGCCGTGAAAA

Product: protease

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSKSSCVWIYKQHNKWCNRPVTKWIHGIPLSKGESHFSSFARHSPILTKKEVNMVKRRSTIWIAISAVVVLIVVAAVSFS
RPATEKNAPVPPRLKPFDTKDAHTHPTVVTLDSLSAGEQLKQRLNEHPRIQEIRHNRRGDRSHYFYNEIIVRFRTTPANH
DIRQMEAAIAGRLVKRLNQAFVFRSHKRTYEEMRRYFRTLPTVDYCEPNYIYMQNDLPRQTDVPNDSFYARYQWNLPAID
TEAGWTLSRGKQTVPVAIIDSGVDLTHPDLAHRLSHGYNVLADNRSPDDENGHGTHVAGIIASQPNNGEGIAGITWFNPI
MAVKVLNADGYGTSIDVAKGIYWAVDRGAKVINLSLGNYQPSSVLEEAIRYADAHDVVLVAASGNDSTSQPSFPAAYPEV
ISVGAVDPDLSYALYSNYGDYVDVVAPGTNIASTFTGHRYAALSGTSMAAPHVTALAALIRSVNPRLTNDEVRNIIIQSA
DDLGDRGKDPHYGYGLINVYRALELAKSAAASS

Sequences:

>Translated_513_residues
MSKSSCVWIYKQHNKWCNRPVTKWIHGIPLSKGESHFSSFARHSPILTKKEVNMVKRRSTIWIAISAVVVLIVVAAVSFS
RPATEKNAPVPPRLKPFDTKDAHTHPTVVTLDSLSAGEQLKQRLNEHPRIQEIRHNRRGDRSHYFYNEIIVRFRTTPANH
DIRQMEAAIAGRLVKRLNQAFVFRSHKRTYEEMRRYFRTLPTVDYCEPNYIYMQNDLPRQTDVPNDSFYARYQWNLPAID
TEAGWTLSRGKQTVPVAIIDSGVDLTHPDLAHRLSHGYNVLADNRSPDDENGHGTHVAGIIASQPNNGEGIAGITWFNPI
MAVKVLNADGYGTSIDVAKGIYWAVDRGAKVINLSLGNYQPSSVLEEAIRYADAHDVVLVAASGNDSTSQPSFPAAYPEV
ISVGAVDPDLSYALYSNYGDYVDVVAPGTNIASTFTGHRYAALSGTSMAAPHVTALAALIRSVNPRLTNDEVRNIIIQSA
DDLGDRGKDPHYGYGLINVYRALELAKSAAASS
>Mature_512_residues
SKSSCVWIYKQHNKWCNRPVTKWIHGIPLSKGESHFSSFARHSPILTKKEVNMVKRRSTIWIAISAVVVLIVVAAVSFSR
PATEKNAPVPPRLKPFDTKDAHTHPTVVTLDSLSAGEQLKQRLNEHPRIQEIRHNRRGDRSHYFYNEIIVRFRTTPANHD
IRQMEAAIAGRLVKRLNQAFVFRSHKRTYEEMRRYFRTLPTVDYCEPNYIYMQNDLPRQTDVPNDSFYARYQWNLPAIDT
EAGWTLSRGKQTVPVAIIDSGVDLTHPDLAHRLSHGYNVLADNRSPDDENGHGTHVAGIIASQPNNGEGIAGITWFNPIM
AVKVLNADGYGTSIDVAKGIYWAVDRGAKVINLSLGNYQPSSVLEEAIRYADAHDVVLVAASGNDSTSQPSFPAAYPEVI
SVGAVDPDLSYALYSNYGDYVDVVAPGTNIASTFTGHRYAALSGTSMAAPHVTALAALIRSVNPRLTNDEVRNIIIQSAD
DLGDRGKDPHYGYGLINVYRALELAKSAAASS

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI31317307, Length=306, Percent_Identity=29.7385620915033, Blast_Score=77, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324576, Length=258, Percent_Identity=36.4341085271318, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320775, Length=297, Percent_Identity=33.6700336700337, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319893, Length=237, Percent_Identity=32.9113924050633, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45550681, Length=298, Percent_Identity=25.8389261744966, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 56930; Mature: 56798

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSSCVWIYKQHNKWCNRPVTKWIHGIPLSKGESHFSSFARHSPILTKKEVNMVKRRST
CCCCCEEEEEECCCCHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCE
IWIAISAVVVLIVVAAVSFSRPATEKNAPVPPRLKPFDTKDAHTHPTVVTLDSLSAGEQL
EEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHH
KQRLNEHPRIQEIRHNRRGDRSHYFYNEIIVRFRTTPANHDIRQMEAAIAGRLVKRLNQA
HHHHCCCCCHHHHHHCCCCCCCHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FVFRSHKRTYEEMRRYFRTLPTVDYCEPNYIYMQNDLPRQTDVPNDSFYARYQWNLPAID
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCC
TEAGWTLSRGKQTVPVAIIDSGVDLTHPDLAHRLSHGYNVLADNRSPDDENGHGTHVAGI
CCCCCEECCCCCEEEEEEEECCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEE
IASQPNNGEGIAGITWFNPIMAVKVLNADGYGTSIDVAKGIYWAVDRGAKVINLSLGNYQ
EEECCCCCCCEEEEHHHCCEEEEEEECCCCCCCEEHHHCCEEEEECCCCEEEEEECCCCC
PSSVLEEAIRYADAHDVVLVAASGNDSTSQPSFPAAYPEVISVGAVDPDLSYALYSNYGD
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCCCCHHHHCCCCC
YVDVVAPGTNIASTFTGHRYAALSGTSMAAPHVTALAALIRSVNPRLTNDEVRNIIIQSA
EEEEEECCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
DDLGDRGKDPHYGYGLINVYRALELAKSAAASS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKSSCVWIYKQHNKWCNRPVTKWIHGIPLSKGESHFSSFARHSPILTKKEVNMVKRRST
CCCCEEEEEECCCCHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCE
IWIAISAVVVLIVVAAVSFSRPATEKNAPVPPRLKPFDTKDAHTHPTVVTLDSLSAGEQL
EEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHH
KQRLNEHPRIQEIRHNRRGDRSHYFYNEIIVRFRTTPANHDIRQMEAAIAGRLVKRLNQA
HHHHCCCCCHHHHHHCCCCCCCHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FVFRSHKRTYEEMRRYFRTLPTVDYCEPNYIYMQNDLPRQTDVPNDSFYARYQWNLPAID
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCC
TEAGWTLSRGKQTVPVAIIDSGVDLTHPDLAHRLSHGYNVLADNRSPDDENGHGTHVAGI
CCCCCEECCCCCEEEEEEEECCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEE
IASQPNNGEGIAGITWFNPIMAVKVLNADGYGTSIDVAKGIYWAVDRGAKVINLSLGNYQ
EEECCCCCCCEEEEHHHCCEEEEEEECCCCCCCEEHHHCCEEEEECCCCEEEEEECCCCC
PSSVLEEAIRYADAHDVVLVAASGNDSTSQPSFPAAYPEVISVGAVDPDLSYALYSNYGD
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCCCCHHHHCCCCC
YVDVVAPGTNIASTFTGHRYAALSGTSMAAPHVTALAALIRSVNPRLTNDEVRNIIIQSA
EEEEEECCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
DDLGDRGKDPHYGYGLINVYRALELAKSAAASS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]