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The map label for this gene is php [C]

Identifier: 138895019

GI number: 138895019

Start: 1444422

End: 1445402

Strand: Direct

Name: php [C]

Synonym: GTNG_1357

Alternate gene names: 138895019

Gene position: 1444422-1445402 (Clockwise)

Preceding gene: 138895018

Following gene: 138895020

Centisome position: 40.68

GC content: 53.21

Gene sequence:

>981_bases
ATGGCAAGGATGGTGGAGACGGTCGTTGGCCCTGTGGCGGCGGATCAGCTTGGCAAAACGCTCATCCATGAACATTTTCT
TTTCGGCTATCCGGGATTTCAAGGCGATGTGACACATGGCCCATTCCGCGAGAACGAAGCACTTTGCGTGGCGATAGAAG
TGGCGGAGAAAATGAAACGGCACGGCATCCAAACGGTCGTCGACCCAACGCCGAACGACTGCGGGCGCAACCCGGCGTTT
TTGCGACGTGTCGCTGAAGAAACTGGACTGAACATCATTTGCGCCACCGGCTATTACTATCAAGGGGAAGGGGCGCCTCC
GTATTTCAAATTTCGCCAGCTGCTCGGGACGGCCGAGGACGATATTTATGGCATGTTTATGACCGAATTGACAGAAGGGA
TTGCCGATACGGGAATCAAAGCCGGTGTCATCAAGCTAGCCTCGAGCAAAGGGCGCATTACCGAGTATGAGAAACTGTTT
TTCCGCGCCGCCGCCCGCGCGCAAAAAGAAACGGGTGCGGTCATCATCACCCACACGCAAGAAGGAACGATGGGGCCGGA
ACAAGCCGCCTATCTGCTTGAGCATGGCGCCGATCCGAAAAAAATTGTCATCGGCCATATGTGTGGCAATACCGACTTAG
ATTACCACCGTCAGACGCTTGCTTACGGCGTATACATTGCTTTTGACCGTTTCGGCATTCAAGGGATGGTCGGCGCTCCG
ATGGATGAAGAACGGGTTCGTACTTTGCTTGCTTTGCTGCGCGATGGGTATGCTCATCAAATCATGCTGTCACACGATAC
GGTCAATCTTTGGCTCGGTCGACCGTTTGCGCTGCCGGAGCCGTTTGCCGAGATGATGAAAAACTGGCATGTGGAGCATT
TGTTTGTGAACATCCTCCCTATATTGAAAAAAGAAGGAATCCGTGACGAAGAGCTTGAGCAAATGTTTGTCCGCAATCCG
GCTGCCTTGTTCTCCGCTTAG

Upstream 100 bases:

>100_bases
AGTTCCGCACATCGCTGCCGATGACATCAAGTGGCAAGCTGCTTTGGCGGAAATTGCAGGAAGAAGAATATGAAAAAGCG
GGGAAAGGGGCGAACACCTA

Downstream 100 bases:

>100_bases
ATGGTCAAAAAGCGCTGCTTTTAATCATGCGGCGGCACAGCTGAACTAACAGTTCGTCTGTCTTCAACAGAGATACAAAG
GGAACCCTCATACGGTCGTT

Product: phosphotriesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MARMVETVVGPVAADQLGKTLIHEHFLFGYPGFQGDVTHGPFRENEALCVAIEVAEKMKRHGIQTVVDPTPNDCGRNPAF
LRRVAEETGLNIICATGYYYQGEGAPPYFKFRQLLGTAEDDIYGMFMTELTEGIADTGIKAGVIKLASSKGRITEYEKLF
FRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDLDYHRQTLAYGVYIAFDRFGIQGMVGAP
MDEERVRTLLALLRDGYAHQIMLSHDTVNLWLGRPFALPEPFAEMMKNWHVEHLFVNILPILKKEGIRDEELEQMFVRNP
AALFSA

Sequences:

>Translated_326_residues
MARMVETVVGPVAADQLGKTLIHEHFLFGYPGFQGDVTHGPFRENEALCVAIEVAEKMKRHGIQTVVDPTPNDCGRNPAF
LRRVAEETGLNIICATGYYYQGEGAPPYFKFRQLLGTAEDDIYGMFMTELTEGIADTGIKAGVIKLASSKGRITEYEKLF
FRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDLDYHRQTLAYGVYIAFDRFGIQGMVGAP
MDEERVRTLLALLRDGYAHQIMLSHDTVNLWLGRPFALPEPFAEMMKNWHVEHLFVNILPILKKEGIRDEELEQMFVRNP
AALFSA
>Mature_325_residues
ARMVETVVGPVAADQLGKTLIHEHFLFGYPGFQGDVTHGPFRENEALCVAIEVAEKMKRHGIQTVVDPTPNDCGRNPAFL
RRVAEETGLNIICATGYYYQGEGAPPYFKFRQLLGTAEDDIYGMFMTELTEGIADTGIKAGVIKLASSKGRITEYEKLFF
RAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDLDYHRQTLAYGVYIAFDRFGIQGMVGAPM
DEERVRTLLALLRDGYAHQIMLSHDTVNLWLGRPFALPEPFAEMMKNWHVEHLFVNILPILKKEGIRDEELEQMFVRNPA
ALFSA

Specific function: Its Real Enzymatic Activity Is Not Yet Known. It Was Tested For General Esterase, Aminopeptidase, Sulfatase, Phosphatase, Carbonic Anhydrase, Phosphodiesterase, And Phosphotriesterase Activities With The Following Substrates: P- Nitrophenyl Acetate, L-Ala

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=360, Percent_Identity=25, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI47933341, Length=360, Percent_Identity=25, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1789780, Length=314, Percent_Identity=30.5732484076433, Blast_Score=136, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645325, Length=358, Percent_Identity=25.9776536312849, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017947
- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 36379; Mature: 36248

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMVETVVGPVAADQLGKTLIHEHFLFGYPGFQGDVTHGPFRENEALCVAIEVAEKMKR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
HGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYQGEGAPPYFKFRQLLGTAED
CCCEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEECCEEECCCCCCHHHHHHHHHCCCCC
DIYGMFMTELTEGIADTGIKAGVIKLASSKGRITEYEKLFFRAAARAQKETGAVIITHTQ
HHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
EGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDLDYHRQTLAYGVYIAFDRFGIQGMVGAP
CCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCC
MDEERVRTLLALLRDGYAHQIMLSHDTVNLWLGRPFALPEPFAEMMKNWHVEHLFVNILP
CCHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHH
ILKKEGIRDEELEQMFVRNPAALFSA
HHHHCCCCHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
ARMVETVVGPVAADQLGKTLIHEHFLFGYPGFQGDVTHGPFRENEALCVAIEVAEKMKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
HGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYQGEGAPPYFKFRQLLGTAED
CCCEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEECCEEECCCCCCHHHHHHHHHCCCCC
DIYGMFMTELTEGIADTGIKAGVIKLASSKGRITEYEKLFFRAAARAQKETGAVIITHTQ
HHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
EGTMGPEQAAYLLEHGADPKKIVIGHMCGNTDLDYHRQTLAYGVYIAFDRFGIQGMVGAP
CCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCC
MDEERVRTLLALLRDGYAHQIMLSHDTVNLWLGRPFALPEPFAEMMKNWHVEHLFVNILP
CCHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHH
ILKKEGIRDEELEQMFVRNPAALFSA
HHHHCCCCHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]