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The map label for this gene is aidB [H]

Identifier: 138895000

GI number: 138895000

Start: 1423986

End: 1425695

Strand: Direct

Name: aidB [H]

Synonym: GTNG_1338

Alternate gene names: 138895000

Gene position: 1423986-1425695 (Clockwise)

Preceding gene: 138894999

Following gene: 138895001

Centisome position: 40.11

GC content: 53.98

Gene sequence:

>1710_bases
ATGATGAGAAAAGAGGAAAGGGGAGGGACGATGAAACCGCTTCGTGAAGCCGATCCGAATTTGCTTGCCAATTTGAAACG
GTATTTGGATGATGAATTGTACCAGTATGCTGAAGAAAAAATTGAATCGTTTTACGAATTTTGCTTGACGGAGGTCGACC
GCCGCGCTGTGCATACCGACCGTGAAGGGCAACCGCGTCTAATGAAGTACGACCGTTTTGGAAACGACATTTCCGAAGTG
TGGGTGAATGAAGGATACGAACAGACGGCGAAACAGACGTATGAAACGGGAATCGTCGGCTATGTGCATAAACCGATTCC
CGAGCTCGGGAAACAAGGAAACTATATTTACTCGTACGCCCAAGGATACATCTTATCGCAAGCCGAGCCCGGGTTTTATT
GCCCGGTGACACTGACGATGGCGACGGCGTATGTGCTTGAACATTTCGCTGATCATGAGTTAAAAACTCGGTACTTGCCT
CATGTCATTTCCACCGGTGAGATCGAGCTGTATGAAGGGGCGACGTTTTTAACTGAGCGGCAAGGCGGGTCGGATGTTGG
GGCCAATGCAGTGCGCGCTGTACCGTGCGGGGATCATTATAAACTGTACGGAGAAAAATATTTTGCCAGCAATGCCGGGC
GCTGCGGCGTAGCGCTCGTGTTGGCGCGCATCGACGGGAGCGGGCCAGGGACGAAAGGGTTGAGCTTGTTTCTCGTTCCA
TGGCGCAACGAGGATGGGACGTTAAACGGCATCACCATCCGCCGTTTAAAGGATAAATTAGGTGTGCGCGCCGTGCCGTC
CGCCGAAGTTGTGTTTGATGGAGCCAAGGCTTATGTCGTCGGCGATCCGCGAAAAGGTTTTTATTATATGATGGAAGCGC
TCAATTTGTCTCGTGTTTGCAATGCGATCGCCTCAGTCGGTATCATGAAGCGGGCGCTCGAGGAAGCGAAACAATACGCC
GAGCGGCGCACGGCGTTTGGCCATCAACTGACCGATTACCCAATGGTGCGCGGGACGCTCGCCGACTTGACGGCGCGTCA
AGAAGTGGAAACGAGCGCCTGCTTTGAGATGGTCGCCTTGTTTGACCGCGTCATGACCGCGCCACATGAGGCAGATGAAT
CGGAGAAAGCATGGCTCAGGCTTCTGATTGCCCTTCTTAAGATGCGTACGGCCGAAGAGGCGATCGCGTTTAGCCATGAA
GCGATTGAAATGCACGGTGGCAACGGGTACATTGAGGATTTTGTCACCCCGCGTCTGCTTCGTGACGCCCAAGTGCTGAC
CGTCTGGGAAGGGACAGCCAACATTTTGGCGCTCGAGGTGCTGCGGCTCATGCGCAAATACCGTATCCACGAGCGGTTTG
CCGCCGAGATGAAGGCACGGCTCGAGAGGGTGGCGGACGAGATGAAGTTGCTCGCTCGTCCCGTGGCAGAGGGGCTTAAG
GAATTGGTGGCAGCACTCGCACGTCTTGGCGGCCAGGCGGAGGAAGTGCAGACATTTCATGCGAAAACGGTGGCCAACCG
GATGTGCGATGTGTATTTGAGCATCATTGCTCTCGAGCGCGGGCAAGAAAATGAGCGAAATCGATTGATCGCTGAGCTGT
TTTTGCAACGTGTCTGGGAGCGGGGGCTTGTCGATGAACGGATGACATCGGTGCGTGAGTTTGACTTGATTGTTCAAGCG
AAAGGAGCAGCGCCGCTTTCGCATTCATGA

Upstream 100 bases:

>100_bases
CCCGCTTGTATGAGGCGATTGCTGAATTGCCGCGCAACGCGACGGGAAAAGTGTTGAAACAAGTGCTCCGGGCGCGGGAG
GCGGCGCAGGAAGTACAGGG

Downstream 100 bases:

>100_bases
GCGGATGGCACGCAAGGGATGATGAGCGAAAGAGATGCACGCTCTTTTGCGGGCATCTCTTTTTGCTAGATGGATAGCTG
CCTAAACGAACAAGTGGGTC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MMRKEERGGTMKPLREADPNLLANLKRYLDDELYQYAEEKIESFYEFCLTEVDRRAVHTDREGQPRLMKYDRFGNDISEV
WVNEGYEQTAKQTYETGIVGYVHKPIPELGKQGNYIYSYAQGYILSQAEPGFYCPVTLTMATAYVLEHFADHELKTRYLP
HVISTGEIELYEGATFLTERQGGSDVGANAVRAVPCGDHYKLYGEKYFASNAGRCGVALVLARIDGSGPGTKGLSLFLVP
WRNEDGTLNGITIRRLKDKLGVRAVPSAEVVFDGAKAYVVGDPRKGFYYMMEALNLSRVCNAIASVGIMKRALEEAKQYA
ERRTAFGHQLTDYPMVRGTLADLTARQEVETSACFEMVALFDRVMTAPHEADESEKAWLRLLIALLKMRTAEEAIAFSHE
AIEMHGGNGYIEDFVTPRLLRDAQVLTVWEGTANILALEVLRLMRKYRIHERFAAEMKARLERVADEMKLLARPVAEGLK
ELVAALARLGGQAEEVQTFHAKTVANRMCDVYLSIIALERGQENERNRLIAELFLQRVWERGLVDERMTSVREFDLIVQA
KGAAPLSHS

Sequences:

>Translated_569_residues
MMRKEERGGTMKPLREADPNLLANLKRYLDDELYQYAEEKIESFYEFCLTEVDRRAVHTDREGQPRLMKYDRFGNDISEV
WVNEGYEQTAKQTYETGIVGYVHKPIPELGKQGNYIYSYAQGYILSQAEPGFYCPVTLTMATAYVLEHFADHELKTRYLP
HVISTGEIELYEGATFLTERQGGSDVGANAVRAVPCGDHYKLYGEKYFASNAGRCGVALVLARIDGSGPGTKGLSLFLVP
WRNEDGTLNGITIRRLKDKLGVRAVPSAEVVFDGAKAYVVGDPRKGFYYMMEALNLSRVCNAIASVGIMKRALEEAKQYA
ERRTAFGHQLTDYPMVRGTLADLTARQEVETSACFEMVALFDRVMTAPHEADESEKAWLRLLIALLKMRTAEEAIAFSHE
AIEMHGGNGYIEDFVTPRLLRDAQVLTVWEGTANILALEVLRLMRKYRIHERFAAEMKARLERVADEMKLLARPVAEGLK
ELVAALARLGGQAEEVQTFHAKTVANRMCDVYLSIIALERGQENERNRLIAELFLQRVWERGLVDERMTSVREFDLIVQA
KGAAPLSHS
>Mature_569_residues
MMRKEERGGTMKPLREADPNLLANLKRYLDDELYQYAEEKIESFYEFCLTEVDRRAVHTDREGQPRLMKYDRFGNDISEV
WVNEGYEQTAKQTYETGIVGYVHKPIPELGKQGNYIYSYAQGYILSQAEPGFYCPVTLTMATAYVLEHFADHELKTRYLP
HVISTGEIELYEGATFLTERQGGSDVGANAVRAVPCGDHYKLYGEKYFASNAGRCGVALVLARIDGSGPGTKGLSLFLVP
WRNEDGTLNGITIRRLKDKLGVRAVPSAEVVFDGAKAYVVGDPRKGFYYMMEALNLSRVCNAIASVGIMKRALEEAKQYA
ERRTAFGHQLTDYPMVRGTLADLTARQEVETSACFEMVALFDRVMTAPHEADESEKAWLRLLIALLKMRTAEEAIAFSHE
AIEMHGGNGYIEDFVTPRLLRDAQVLTVWEGTANILALEVLRLMRKYRIHERFAAEMKARLERVADEMKLLARPVAEGLK
ELVAALARLGGQAEEVQTFHAKTVANRMCDVYLSIIALERGQENERNRLIAELFLQRVWERGLVDERMTSVREFDLIVQA
KGAAPLSHS

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=367, Percent_Identity=31.3351498637602, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI226958412, Length=292, Percent_Identity=32.1917808219178, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226958414, Length=292, Percent_Identity=32.1917808219178, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI76496475, Length=297, Percent_Identity=29.6296296296296, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI4557235, Length=297, Percent_Identity=29.6296296296296, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI7656849, Length=310, Percent_Identity=27.0967741935484, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI21361497, Length=344, Percent_Identity=29.0697674418605, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=27.5590551181102, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI4501859, Length=311, Percent_Identity=27.6527331189711, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4557231, Length=275, Percent_Identity=29.0909090909091, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI187960098, Length=275, Percent_Identity=29.0909090909091, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4503943, Length=360, Percent_Identity=25.2777777777778, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7669494, Length=352, Percent_Identity=24.4318181818182, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082384, Length=483, Percent_Identity=29.6066252587992, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081958, Length=263, Percent_Identity=27.3764258555133, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=565, Percent_Identity=30.6194690265487, Blast_Score=228, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI86563383, Length=565, Percent_Identity=30.6194690265487, Blast_Score=228, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17538396, Length=297, Percent_Identity=32.3232323232323, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17533517, Length=310, Percent_Identity=28.3870967741935, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=363, Percent_Identity=26.4462809917355, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=359, Percent_Identity=26.7409470752089, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=313, Percent_Identity=26.8370607028754, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=297, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=354, Percent_Identity=27.1186440677966, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=292, Percent_Identity=26.027397260274, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=243, Percent_Identity=29.2181069958848, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=252, Percent_Identity=29.7619047619048, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=306, Percent_Identity=23.5294117647059, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=201, Percent_Identity=30.8457711442786, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=360, Percent_Identity=21.3888888888889, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=401, Percent_Identity=23.9401496259352, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=352, Percent_Identity=29.8295454545455, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21355753, Length=287, Percent_Identity=30.3135888501742, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646207, Length=277, Percent_Identity=29.9638989169675, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281363737, Length=299, Percent_Identity=31.1036789297659, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=24.585635359116, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24660351, Length=354, Percent_Identity=27.4011299435028, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19920834, Length=312, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 64243; Mature: 64243

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRKEERGGTMKPLREADPNLLANLKRYLDDELYQYAEEKIESFYEFCLTEVDRRAVHTD
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
REGQPRLMKYDRFGNDISEVWVNEGYEQTAKQTYETGIVGYVHKPIPELGKQGNYIYSYA
CCCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCHHHHCCCCCEEEEEC
QGYILSQAEPGFYCPVTLTMATAYVLEHFADHELKTRYLPHVISTGEIELYEGATFLTER
CCEEEECCCCCEECHHHHHHHHHHHHHHHHCCHHHHHHHCHHHCCCCEEEECCCEEEECC
QGGSDVGANAVRAVPCGDHYKLYGEKYFASNAGRCGVALVLARIDGSGPGTKGLSLFLVP
CCCCCCCCCCEEECCCCCCHHHCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEE
WRNEDGTLNGITIRRLKDKLGVRAVPSAEVVFDGAKAYVVGDPRKGFYYMMEALNLSRVC
ECCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
NAIASVGIMKRALEEAKQYAERRTAFGHQLTDYPMVRGTLADLTARQEVETSACFEMVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FDRVMTAPHEADESEKAWLRLLIALLKMRTAEEAIAFSHEAIEMHGGNGYIEDFVTPRLL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHCCHHHH
RDAQVLTVWEGTANILALEVLRLMRKYRIHERFAAEMKARLERVADEMKLLARPVAEGLK
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVAALARLGGQAEEVQTFHAKTVANRMCDVYLSIIALERGQENERNRLIAELFLQRVWE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RGLVDERMTSVREFDLIVQAKGAAPLSHS
CCCHHHHHHHHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure
MMRKEERGGTMKPLREADPNLLANLKRYLDDELYQYAEEKIESFYEFCLTEVDRRAVHTD
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
REGQPRLMKYDRFGNDISEVWVNEGYEQTAKQTYETGIVGYVHKPIPELGKQGNYIYSYA
CCCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCHHHHCCCCCEEEEEC
QGYILSQAEPGFYCPVTLTMATAYVLEHFADHELKTRYLPHVISTGEIELYEGATFLTER
CCEEEECCCCCEECHHHHHHHHHHHHHHHHCCHHHHHHHCHHHCCCCEEEECCCEEEECC
QGGSDVGANAVRAVPCGDHYKLYGEKYFASNAGRCGVALVLARIDGSGPGTKGLSLFLVP
CCCCCCCCCCEEECCCCCCHHHCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEE
WRNEDGTLNGITIRRLKDKLGVRAVPSAEVVFDGAKAYVVGDPRKGFYYMMEALNLSRVC
ECCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
NAIASVGIMKRALEEAKQYAERRTAFGHQLTDYPMVRGTLADLTARQEVETSACFEMVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FDRVMTAPHEADESEKAWLRLLIALLKMRTAEEAIAFSHEAIEMHGGNGYIEDFVTPRLL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHCCHHHH
RDAQVLTVWEGTANILALEVLRLMRKYRIHERFAAEMKARLERVADEMKLLARPVAEGLK
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVAALARLGGQAEEVQTFHAKTVANRMCDVYLSIIALERGQENERNRLIAELFLQRVWE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RGLVDERMTSVREFDLIVQAKGAAPLSHS
CCCHHHHHHHHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]