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The map label for this gene is feoB2 [H]

Identifier: 138894989

GI number: 138894989

Start: 1413145

End: 1414539

Strand: Reverse

Name: feoB2 [H]

Synonym: GTNG_1327

Alternate gene names: 138894989

Gene position: 1414539-1413145 (Counterclockwise)

Preceding gene: 138894990

Following gene: 138894979

Centisome position: 39.84

GC content: 53.55

Gene sequence:

>1395_bases
ATGCATGTTGCGGATCGGTCAAATCTGTTTGATCGTTTAATGGAAGAAGCACAATCGTTGGCACCAGCCGATACGCGCGA
ACAAATCGTCACCGCCATCTTTCAAACATCAGCCGCGCTTTGCCGGGAAACGGTCACAAATGCGCCTAAGGCCGCAAAAG
ACCACACTTTGCAAATCGATCGGATCGTCACATCGCGGCGCTGGGGATTCGTCATCATGCTGGCGATGCTCGCCGCTGTC
CTTTACATGACGATCGCTGGAGCAAACGTATTGTCTGAATCGCTTGCCCACCTGTTCGGATGGGTAGAACAATATTTGAC
CCTGTTGTTTCAAGCCGTTCATGCACCTCACTGGTTGTACGGCCTCCTTGTGCTTGGCTTATACCGCGGCACCGCGTGGG
TCGTCAGCGTGATGTTGCCGCCGATGGCCATTTTCTTTCCAGTGTTCGCCTTGCTCGAGAATTATGGCTATTTGCCACGC
GTCGCCTTCAATCTTGACCGCCTGTTTAAAAAGGCGGGCGCACACGGCAAACAGGCGCTGACGATGGCTATGGGCTTTGG
ATGCAACGCCGCCGCCGTCATCTCAACACGCATTATCGAATCGCCGCGTGAGCGGACGCTCGCCATTTTGACGAACAGTT
TCGTTCCTTGCAACGGACGATGGCCGACGTTGATTTTGCTCTCTTCCTTATTTATGGCAGCTGGTTATACAGGGAGCTGG
AACACACTCGTCACTGCCGCGGTGGTCGTCGCCATGGTACTGTTTGGCATCATTGTCACGTTAACCGTTTCATGGGTCCT
ATCCAAGACAGCCTTGCGCGGCATCCCAACCCATTACACTTTGGAACTGCCGCCATATCGGCGCCCGAAAATCGCTGAGA
CCGTCATTCGCGCCACACTGGATAAAACGTGGTACGTACTCAAACGCGCCGTCACCGTCGCCGCCCCAGCTGGTGTCATC
ACTTGGGTGCTCGGCAACGTCCCCATCGGCGACACAACCGCGCTTTCCGCTTTCGCTAGTTGGCTCGATCCGTTTGCGAA
GACCATCGGACTTGACGGCTATATTTTGATGGCTTTTCTCTTAGGGCTTCCAGCCAACGAAATCGTCTTGCCGGTTTTGT
TGATGGGATATTTATCGGCCGGAGCGTTAACGGAAATCGATAGCCTCCATTCGCTCAAACATATTTTTCTCGCTCATGGA
TGGACGTGGCTGACGGCACTCAATATGATGCTGTTTTCACTTCTCCACTACCCGTGCGGCACGACGCTTGTCAACATTTA
CAAAGAAACGAAAAGCACGAAATGGACGTTCGTTGCCTTTGCCTTGCCGACAGCAATTGCTGTTGCCGTCACCTTTACGA
CCGCTCGGCTAGCGAGATGGCTTGGACTCGTATGA

Upstream 100 bases:

>100_bases
CCGGCTCGCTGGGTCGCACTCCGGCTGCTTGACGGTGATACCTCACTTCTTAGCGCTTTGAACCAGCAGCCGCCACGGCT
CACAAAGGAGGAAGCTCCGT

Downstream 100 bases:

>100_bases
CTATTGTGACGAAGAAATCAAACTATCACGCTACAAAGGAAACGATATACTTCTGCCATGAAGATCGTTCGCTCCCTCTA
TTTTTAGGGACAGAGGCGTT

Product: ferrous iron transport protein

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MHVADRSNLFDRLMEEAQSLAPADTREQIVTAIFQTSAALCRETVTNAPKAAKDHTLQIDRIVTSRRWGFVIMLAMLAAV
LYMTIAGANVLSESLAHLFGWVEQYLTLLFQAVHAPHWLYGLLVLGLYRGTAWVVSVMLPPMAIFFPVFALLENYGYLPR
VAFNLDRLFKKAGAHGKQALTMAMGFGCNAAAVISTRIIESPRERTLAILTNSFVPCNGRWPTLILLSSLFMAAGYTGSW
NTLVTAAVVVAMVLFGIIVTLTVSWVLSKTALRGIPTHYTLELPPYRRPKIAETVIRATLDKTWYVLKRAVTVAAPAGVI
TWVLGNVPIGDTTALSAFASWLDPFAKTIGLDGYILMAFLLGLPANEIVLPVLLMGYLSAGALTEIDSLHSLKHIFLAHG
WTWLTALNMMLFSLLHYPCGTTLVNIYKETKSTKWTFVAFALPTAIAVAVTFTTARLARWLGLV

Sequences:

>Translated_464_residues
MHVADRSNLFDRLMEEAQSLAPADTREQIVTAIFQTSAALCRETVTNAPKAAKDHTLQIDRIVTSRRWGFVIMLAMLAAV
LYMTIAGANVLSESLAHLFGWVEQYLTLLFQAVHAPHWLYGLLVLGLYRGTAWVVSVMLPPMAIFFPVFALLENYGYLPR
VAFNLDRLFKKAGAHGKQALTMAMGFGCNAAAVISTRIIESPRERTLAILTNSFVPCNGRWPTLILLSSLFMAAGYTGSW
NTLVTAAVVVAMVLFGIIVTLTVSWVLSKTALRGIPTHYTLELPPYRRPKIAETVIRATLDKTWYVLKRAVTVAAPAGVI
TWVLGNVPIGDTTALSAFASWLDPFAKTIGLDGYILMAFLLGLPANEIVLPVLLMGYLSAGALTEIDSLHSLKHIFLAHG
WTWLTALNMMLFSLLHYPCGTTLVNIYKETKSTKWTFVAFALPTAIAVAVTFTTARLARWLGLV
>Mature_464_residues
MHVADRSNLFDRLMEEAQSLAPADTREQIVTAIFQTSAALCRETVTNAPKAAKDHTLQIDRIVTSRRWGFVIMLAMLAAV
LYMTIAGANVLSESLAHLFGWVEQYLTLLFQAVHAPHWLYGLLVLGLYRGTAWVVSVMLPPMAIFFPVFALLENYGYLPR
VAFNLDRLFKKAGAHGKQALTMAMGFGCNAAAVISTRIIESPRERTLAILTNSFVPCNGRWPTLILLSSLFMAAGYTGSW
NTLVTAAVVVAMVLFGIIVTLTVSWVLSKTALRGIPTHYTLELPPYRRPKIAETVIRATLDKTWYVLKRAVTVAAPAGVI
TWVLGNVPIGDTTALSAFASWLDPFAKTIGLDGYILMAFLLGLPANEIVLPVLLMGYLSAGALTEIDSLHSLKHIFLAHG
WTWLTALNMMLFSLLHYPCGTTLVNIYKETKSTKWTFVAFALPTAIAVAVTFTTARLARWLGLV

Specific function: Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=327, Percent_Identity=29.3577981651376, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50992; Mature: 50992

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVADRSNLFDRLMEEAQSLAPADTREQIVTAIFQTSAALCRETVTNAPKAAKDHTLQID
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
RIVTSRRWGFVIMLAMLAAVLYMTIAGANVLSESLAHLFGWVEQYLTLLFQAVHAPHWLY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GLLVLGLYRGTAWVVSVMLPPMAIFFPVFALLENYGYLPRVAFNLDRLFKKAGAHGKQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHH
TMAMGFGCNAAAVISTRIIESPRERTLAILTNSFVPCNGRWPTLILLSSLFMAAGYTGSW
HHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
NTLVTAAVVVAMVLFGIIVTLTVSWVLSKTALRGIPTHYTLELPPYRRPKIAETVIRATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH
DKTWYVLKRAVTVAAPAGVITWVLGNVPIGDTTALSAFASWLDPFAKTIGLDGYILMAFL
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGLPANEIVLPVLLMGYLSAGALTEIDSLHSLKHIFLAHGWTWLTALNMMLFSLLHYPCG
HCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
TTLVNIYKETKSTKWTFVAFALPTAIAVAVTFTTARLARWLGLV
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHVADRSNLFDRLMEEAQSLAPADTREQIVTAIFQTSAALCRETVTNAPKAAKDHTLQID
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
RIVTSRRWGFVIMLAMLAAVLYMTIAGANVLSESLAHLFGWVEQYLTLLFQAVHAPHWLY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GLLVLGLYRGTAWVVSVMLPPMAIFFPVFALLENYGYLPRVAFNLDRLFKKAGAHGKQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHH
TMAMGFGCNAAAVISTRIIESPRERTLAILTNSFVPCNGRWPTLILLSSLFMAAGYTGSW
HHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
NTLVTAAVVVAMVLFGIIVTLTVSWVLSKTALRGIPTHYTLELPPYRRPKIAETVIRATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH
DKTWYVLKRAVTVAAPAGVITWVLGNVPIGDTTALSAFASWLDPFAKTIGLDGYILMAFL
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGLPANEIVLPVLLMGYLSAGALTEIDSLHSLKHIFLAHGWTWLTALNMMLFSLLHYPCG
HCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
TTLVNIYKETKSTKWTFVAFALPTAIAVAVTFTTARLARWLGLV
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]